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Cellular migration and formation of neuronal connections [[electronic resource] /] / editors-in-chief, John L.R. Rubenstein, Pasko Rakic
Cellular migration and formation of neuronal connections [[electronic resource] /] / editors-in-chief, John L.R. Rubenstein, Pasko Rakic
Edizione [1st ed.]
Pubbl/distr/stampa Amsterdam ; ; Boston, : Elsevier/AP, 2013
Descrizione fisica 1 online resource (1081 p.)
Disciplina 612.8
Altri autori (Persone) RubensteinJohn L. R
RakicPasko
Collana Comprehensive developmental neuroscience
Soggetto topico Developmental neurobiology
Neurons - Growth
Neurons - Physiology
Axons - Growth
Axons - Physiology
Dendrites - Growth
Dendrites - Physiology
Cellular signal transduction - Physiology
Soggetto genere / forma Electronic books.
ISBN 0-12-397347-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto section 1. Formation of axons and dendrites -- section 2. Migration -- section 3. Synaptogenesis -- section 4. Developmental sequences in the maturation of intrinsic and synapse driven patterns.
Record Nr. UNINA-9910459131303321
Amsterdam ; ; Boston, : Elsevier/AP, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cellular migration and formation of neuronal connections / / editors-in-chief, Professor John L.R. Rubenstein, Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA, Professor Pasko Rakic, Duberg Professor of Neurobiology and Neurology, Director Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA
Cellular migration and formation of neuronal connections / / editors-in-chief, Professor John L.R. Rubenstein, Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA, Professor Pasko Rakic, Duberg Professor of Neurobiology and Neurology, Director Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA
Edizione [1st ed.]
Pubbl/distr/stampa Amsterdam ; ; Boston, : Elsevier/AP, 2013
Descrizione fisica 1 online resource (xi, 1068 pages) : illustrations (some color)
Disciplina 612.8
Collana Comprehensive developmental neuroscience
Soggetto topico Developmental neurobiology
Neurons - Growth
Neurons - Physiology
Axons - Growth
Axons - Physiology
Dendrites - Growth
Dendrites - Physiology
Cellular signal transduction - Physiology
ISBN 0-12-397347-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto section 1. Formation of axons and dendrites -- section 2. Migration -- section 3. Synaptogenesis -- section 4. Developmental sequences in the maturation of intrinsic and synapse driven patterns.
Record Nr. UNINA-9910792478403321
Amsterdam ; ; Boston, : Elsevier/AP, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cellular migration and formation of neuronal connections / / editors-in-chief, Professor John L.R. Rubenstein, Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA, Professor Pasko Rakic, Duberg Professor of Neurobiology and Neurology, Director Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA
Cellular migration and formation of neuronal connections / / editors-in-chief, Professor John L.R. Rubenstein, Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA, Professor Pasko Rakic, Duberg Professor of Neurobiology and Neurology, Director Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA
Edizione [1st ed.]
Pubbl/distr/stampa Amsterdam ; ; Boston, : Elsevier/AP, 2013
Descrizione fisica 1 online resource (xi, 1068 pages) : illustrations (some color)
Disciplina 612.8
Collana Comprehensive developmental neuroscience
Soggetto topico Developmental neurobiology
Neurons - Growth
Neurons - Physiology
Axons - Growth
Axons - Physiology
Dendrites - Growth
Dendrites - Physiology
Cellular signal transduction - Physiology
ISBN 0-12-397347-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto section 1. Formation of axons and dendrites -- section 2. Migration -- section 3. Synaptogenesis -- section 4. Developmental sequences in the maturation of intrinsic and synapse driven patterns.
Record Nr. UNINA-9910822030603321
Amsterdam ; ; Boston, : Elsevier/AP, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Lysophospholipid receptors [[electronic resource] ] : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Lysophospholipid receptors [[electronic resource] ] : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley, c2013
Descrizione fisica 1 online resource (813 p.)
Disciplina 571.7/4
Altri autori (Persone) ChunJerold <1959->
Soggetto topico Cell receptors - Physiology
Cell receptors - Metabolism
Cellular signal transduction - Physiology
ISBN 1-118-53142-6
1-118-53135-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title page; Copyright page; Contents; Preface; Contributors; CHAPTER 1: Lysophosphatidic Acid (LPA) Receptor Signaling; 1.1. Introduction; 1.2. LPA Metabolism; 1.3. Autotaxin; 1.4. LPA Receptors; 1.4.1. LPA1; 1.4.2. LPA2; 1.4.3. LPA3; 1.4.4. LPA4; 1.4.5. LPA5; 1.4.6. LPA6; 1.5. LPA Receptor Agonists and Antagonists; References; CHAPTER 2: Sphingosine 1-Phosphate (S1P) Receptors; 2.1. Introduction; 2.2. S1P Metabolism/Enzyme, and Transport; 2.2.1. S1P Metabolism and Enzymes; 2.2.2. Sphingosine Kinases; 2.2.3. S1P Phosphatases and S1P Lyase
2.3. S1P Receptor Subtypes, and Physiological Functions2.3.1. S1P1; 2.3.2. S1P2; 2.3.3. S1P3; 2.3.4. S1P4; 2.3.5. S1P5; 2.4. Concluding Remarks; References; CHAPTER 3: Global Gene Expression Program of Lysophosphatidic Acid (LPA)-Stimulated Fibroblasts; 3.1. Introduction; 3.2. The Global Transcriptional Response of MEFs to LPA; 3.3. Upregulated Genes; 3.4. Downregulated Genes; 3.5. Induction of Genes that Encode Secreted Factors; 3.6. Overlap between the Expression Profiles of LPA and EGF; 3.7. Conclusions; Acknowledgments; References
CHAPTER 4: Identification of Direct Intracellular Targets of Sphingosine 1-Phosphate (S1P)4.1. Introduction; 4.2. Intracellular Targets for S1P; 4.3. Methods to Identify Intracellular S1P Targets; 4.3.1. S1P Immobilized on Agarose Beads; 4.3.2. Binding of 32P-Labeled S1P to Targets; 4.3.3. Mass Measurement of Endogenous S1P in Immunoprecipitates of Target Proteins; 4.4. Other Potentially Useful Methods to Identify Lipid Binding Proteins; 4.4.1. Lipid Strips for Identification of Binding Proteins (Protein-Lipid Overlay)
4.4.2. Detection of Lipid Binding Proteins by Enzyme-Linked Immunadsorbent Assays4.4.3. Liposome Pull Down; 4.5. Concluding Remarks; Acknowledgments; References; CHAPTER 5: Lysophospholipid Receptor Signaling Platforms: The Receptor Tyrosine Kinase-G Protein-Coupled Receptor Signaling Complex; 5.1. Introduction; 5.2. Lysophospholipid Receptor-Receptor Tyrosine Kinase Complexes; 5.3. Other Lysophospholipid Receptor Signaling Platforms; 5.4. Other Examples of RTK-GPCR Signaling Platforms
5.5. Interaction of RGS Proteins with Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes5.6. S1P and RTK Transactivation; 5.7. Approaches for the Study of Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes; 5.8. Some Useful Protocols for Studying RTK-Lysophospholipid Receptor Signaling Platforms; 5.8.1. Compounds; 5.8.2. Cells; 5.8.3. Immunoprecipitation; 5.8.4. Immunofluorescence; 5.8.5. GTP-γ-S Binding Assay; 5.8.6. Cell Migration; 5.9. Conclusion; Acknowledgment; References
CHAPTER 6: Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions
Record Nr. UNINA-9910141615303321
Hoboken, N.J., : Wiley, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Lysophospholipid receptors : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Lysophospholipid receptors : signaling and biochemistry / / edited by Jerold Chun ... [et al.]
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley, c2013
Descrizione fisica 1 online resource (813 p.)
Disciplina 571.7/4
Altri autori (Persone) ChunJerold <1959->
Soggetto topico Cell receptors - Physiology
Cell receptors - Metabolism
Cellular signal transduction - Physiology
ISBN 1-118-53142-6
1-118-53135-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title page; Copyright page; Contents; Preface; Contributors; CHAPTER 1: Lysophosphatidic Acid (LPA) Receptor Signaling; 1.1. Introduction; 1.2. LPA Metabolism; 1.3. Autotaxin; 1.4. LPA Receptors; 1.4.1. LPA1; 1.4.2. LPA2; 1.4.3. LPA3; 1.4.4. LPA4; 1.4.5. LPA5; 1.4.6. LPA6; 1.5. LPA Receptor Agonists and Antagonists; References; CHAPTER 2: Sphingosine 1-Phosphate (S1P) Receptors; 2.1. Introduction; 2.2. S1P Metabolism/Enzyme, and Transport; 2.2.1. S1P Metabolism and Enzymes; 2.2.2. Sphingosine Kinases; 2.2.3. S1P Phosphatases and S1P Lyase
2.3. S1P Receptor Subtypes, and Physiological Functions2.3.1. S1P1; 2.3.2. S1P2; 2.3.3. S1P3; 2.3.4. S1P4; 2.3.5. S1P5; 2.4. Concluding Remarks; References; CHAPTER 3: Global Gene Expression Program of Lysophosphatidic Acid (LPA)-Stimulated Fibroblasts; 3.1. Introduction; 3.2. The Global Transcriptional Response of MEFs to LPA; 3.3. Upregulated Genes; 3.4. Downregulated Genes; 3.5. Induction of Genes that Encode Secreted Factors; 3.6. Overlap between the Expression Profiles of LPA and EGF; 3.7. Conclusions; Acknowledgments; References
CHAPTER 4: Identification of Direct Intracellular Targets of Sphingosine 1-Phosphate (S1P)4.1. Introduction; 4.2. Intracellular Targets for S1P; 4.3. Methods to Identify Intracellular S1P Targets; 4.3.1. S1P Immobilized on Agarose Beads; 4.3.2. Binding of 32P-Labeled S1P to Targets; 4.3.3. Mass Measurement of Endogenous S1P in Immunoprecipitates of Target Proteins; 4.4. Other Potentially Useful Methods to Identify Lipid Binding Proteins; 4.4.1. Lipid Strips for Identification of Binding Proteins (Protein-Lipid Overlay)
4.4.2. Detection of Lipid Binding Proteins by Enzyme-Linked Immunadsorbent Assays4.4.3. Liposome Pull Down; 4.5. Concluding Remarks; Acknowledgments; References; CHAPTER 5: Lysophospholipid Receptor Signaling Platforms: The Receptor Tyrosine Kinase-G Protein-Coupled Receptor Signaling Complex; 5.1. Introduction; 5.2. Lysophospholipid Receptor-Receptor Tyrosine Kinase Complexes; 5.3. Other Lysophospholipid Receptor Signaling Platforms; 5.4. Other Examples of RTK-GPCR Signaling Platforms
5.5. Interaction of RGS Proteins with Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes5.6. S1P and RTK Transactivation; 5.7. Approaches for the Study of Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes; 5.8. Some Useful Protocols for Studying RTK-Lysophospholipid Receptor Signaling Platforms; 5.8.1. Compounds; 5.8.2. Cells; 5.8.3. Immunoprecipitation; 5.8.4. Immunofluorescence; 5.8.5. GTP-γ-S Binding Assay; 5.8.6. Cell Migration; 5.9. Conclusion; Acknowledgment; References
CHAPTER 6: Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions
Record Nr. UNINA-9910808700503321
Hoboken, N.J., : Wiley, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui