Cellular migration and formation of neuronal connections [[electronic resource] /] / editors-in-chief, John L.R. Rubenstein, Pasko Rakic |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier/AP, 2013 |
Descrizione fisica | 1 online resource (1081 p.) |
Disciplina | 612.8 |
Altri autori (Persone) |
RubensteinJohn L. R
RakicPasko |
Collana | Comprehensive developmental neuroscience |
Soggetto topico |
Developmental neurobiology
Neurons - Growth Neurons - Physiology Axons - Growth Axons - Physiology Dendrites - Growth Dendrites - Physiology Cellular signal transduction - Physiology |
Soggetto genere / forma | Electronic books. |
ISBN | 0-12-397347-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | section 1. Formation of axons and dendrites -- section 2. Migration -- section 3. Synaptogenesis -- section 4. Developmental sequences in the maturation of intrinsic and synapse driven patterns. |
Record Nr. | UNINA-9910459131303321 |
Amsterdam ; ; Boston, : Elsevier/AP, 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cellular migration and formation of neuronal connections / / editors-in-chief, Professor John L.R. Rubenstein, Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA, Professor Pasko Rakic, Duberg Professor of Neurobiology and Neurology, Director Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier/AP, 2013 |
Descrizione fisica | 1 online resource (xi, 1068 pages) : illustrations (some color) |
Disciplina | 612.8 |
Collana | Comprehensive developmental neuroscience |
Soggetto topico |
Developmental neurobiology
Neurons - Growth Neurons - Physiology Axons - Growth Axons - Physiology Dendrites - Growth Dendrites - Physiology Cellular signal transduction - Physiology |
ISBN | 0-12-397347-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | section 1. Formation of axons and dendrites -- section 2. Migration -- section 3. Synaptogenesis -- section 4. Developmental sequences in the maturation of intrinsic and synapse driven patterns. |
Record Nr. | UNINA-9910792478403321 |
Amsterdam ; ; Boston, : Elsevier/AP, 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
|
Cellular migration and formation of neuronal connections / / editors-in-chief, Professor John L.R. Rubenstein, Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA, Professor Pasko Rakic, Duberg Professor of Neurobiology and Neurology, Director Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier/AP, 2013 |
Descrizione fisica | 1 online resource (xi, 1068 pages) : illustrations (some color) |
Disciplina | 612.8 |
Collana | Comprehensive developmental neuroscience |
Soggetto topico |
Developmental neurobiology
Neurons - Growth Neurons - Physiology Axons - Growth Axons - Physiology Dendrites - Growth Dendrites - Physiology Cellular signal transduction - Physiology |
ISBN | 0-12-397347-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | section 1. Formation of axons and dendrites -- section 2. Migration -- section 3. Synaptogenesis -- section 4. Developmental sequences in the maturation of intrinsic and synapse driven patterns. |
Record Nr. | UNINA-9910822030603321 |
Amsterdam ; ; Boston, : Elsevier/AP, 2013 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
Lysophospholipid receptors [[electronic resource] ] : signaling and biochemistry / / edited by Jerold Chun ... [et al.] |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2013 |
Descrizione fisica | 1 online resource (813 p.) |
Disciplina | 571.7/4 |
Altri autori (Persone) | ChunJerold <1959-> |
Soggetto topico |
Cell receptors - Physiology
Cell receptors - Metabolism Cellular signal transduction - Physiology |
ISBN |
1-118-53142-6
1-118-53135-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Title page; Copyright page; Contents; Preface; Contributors; CHAPTER 1: Lysophosphatidic Acid (LPA) Receptor Signaling; 1.1. Introduction; 1.2. LPA Metabolism; 1.3. Autotaxin; 1.4. LPA Receptors; 1.4.1. LPA1; 1.4.2. LPA2; 1.4.3. LPA3; 1.4.4. LPA4; 1.4.5. LPA5; 1.4.6. LPA6; 1.5. LPA Receptor Agonists and Antagonists; References; CHAPTER 2: Sphingosine 1-Phosphate (S1P) Receptors; 2.1. Introduction; 2.2. S1P Metabolism/Enzyme, and Transport; 2.2.1. S1P Metabolism and Enzymes; 2.2.2. Sphingosine Kinases; 2.2.3. S1P Phosphatases and S1P Lyase
2.3. S1P Receptor Subtypes, and Physiological Functions2.3.1. S1P1; 2.3.2. S1P2; 2.3.3. S1P3; 2.3.4. S1P4; 2.3.5. S1P5; 2.4. Concluding Remarks; References; CHAPTER 3: Global Gene Expression Program of Lysophosphatidic Acid (LPA)-Stimulated Fibroblasts; 3.1. Introduction; 3.2. The Global Transcriptional Response of MEFs to LPA; 3.3. Upregulated Genes; 3.4. Downregulated Genes; 3.5. Induction of Genes that Encode Secreted Factors; 3.6. Overlap between the Expression Profiles of LPA and EGF; 3.7. Conclusions; Acknowledgments; References CHAPTER 4: Identification of Direct Intracellular Targets of Sphingosine 1-Phosphate (S1P)4.1. Introduction; 4.2. Intracellular Targets for S1P; 4.3. Methods to Identify Intracellular S1P Targets; 4.3.1. S1P Immobilized on Agarose Beads; 4.3.2. Binding of 32P-Labeled S1P to Targets; 4.3.3. Mass Measurement of Endogenous S1P in Immunoprecipitates of Target Proteins; 4.4. Other Potentially Useful Methods to Identify Lipid Binding Proteins; 4.4.1. Lipid Strips for Identification of Binding Proteins (Protein-Lipid Overlay) 4.4.2. Detection of Lipid Binding Proteins by Enzyme-Linked Immunadsorbent Assays4.4.3. Liposome Pull Down; 4.5. Concluding Remarks; Acknowledgments; References; CHAPTER 5: Lysophospholipid Receptor Signaling Platforms: The Receptor Tyrosine Kinase-G Protein-Coupled Receptor Signaling Complex; 5.1. Introduction; 5.2. Lysophospholipid Receptor-Receptor Tyrosine Kinase Complexes; 5.3. Other Lysophospholipid Receptor Signaling Platforms; 5.4. Other Examples of RTK-GPCR Signaling Platforms 5.5. Interaction of RGS Proteins with Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes5.6. S1P and RTK Transactivation; 5.7. Approaches for the Study of Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes; 5.8. Some Useful Protocols for Studying RTK-Lysophospholipid Receptor Signaling Platforms; 5.8.1. Compounds; 5.8.2. Cells; 5.8.3. Immunoprecipitation; 5.8.4. Immunofluorescence; 5.8.5. GTP-γ-S Binding Assay; 5.8.6. Cell Migration; 5.9. Conclusion; Acknowledgment; References CHAPTER 6: Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions |
Record Nr. | UNINA-9910141615303321 |
Hoboken, N.J., : Wiley, c2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Lysophospholipid receptors : signaling and biochemistry / / edited by Jerold Chun ... [et al.] |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2013 |
Descrizione fisica | 1 online resource (813 p.) |
Disciplina | 571.7/4 |
Altri autori (Persone) | ChunJerold <1959-> |
Soggetto topico |
Cell receptors - Physiology
Cell receptors - Metabolism Cellular signal transduction - Physiology |
ISBN |
1-118-53142-6
1-118-53135-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Title page; Copyright page; Contents; Preface; Contributors; CHAPTER 1: Lysophosphatidic Acid (LPA) Receptor Signaling; 1.1. Introduction; 1.2. LPA Metabolism; 1.3. Autotaxin; 1.4. LPA Receptors; 1.4.1. LPA1; 1.4.2. LPA2; 1.4.3. LPA3; 1.4.4. LPA4; 1.4.5. LPA5; 1.4.6. LPA6; 1.5. LPA Receptor Agonists and Antagonists; References; CHAPTER 2: Sphingosine 1-Phosphate (S1P) Receptors; 2.1. Introduction; 2.2. S1P Metabolism/Enzyme, and Transport; 2.2.1. S1P Metabolism and Enzymes; 2.2.2. Sphingosine Kinases; 2.2.3. S1P Phosphatases and S1P Lyase
2.3. S1P Receptor Subtypes, and Physiological Functions2.3.1. S1P1; 2.3.2. S1P2; 2.3.3. S1P3; 2.3.4. S1P4; 2.3.5. S1P5; 2.4. Concluding Remarks; References; CHAPTER 3: Global Gene Expression Program of Lysophosphatidic Acid (LPA)-Stimulated Fibroblasts; 3.1. Introduction; 3.2. The Global Transcriptional Response of MEFs to LPA; 3.3. Upregulated Genes; 3.4. Downregulated Genes; 3.5. Induction of Genes that Encode Secreted Factors; 3.6. Overlap between the Expression Profiles of LPA and EGF; 3.7. Conclusions; Acknowledgments; References CHAPTER 4: Identification of Direct Intracellular Targets of Sphingosine 1-Phosphate (S1P)4.1. Introduction; 4.2. Intracellular Targets for S1P; 4.3. Methods to Identify Intracellular S1P Targets; 4.3.1. S1P Immobilized on Agarose Beads; 4.3.2. Binding of 32P-Labeled S1P to Targets; 4.3.3. Mass Measurement of Endogenous S1P in Immunoprecipitates of Target Proteins; 4.4. Other Potentially Useful Methods to Identify Lipid Binding Proteins; 4.4.1. Lipid Strips for Identification of Binding Proteins (Protein-Lipid Overlay) 4.4.2. Detection of Lipid Binding Proteins by Enzyme-Linked Immunadsorbent Assays4.4.3. Liposome Pull Down; 4.5. Concluding Remarks; Acknowledgments; References; CHAPTER 5: Lysophospholipid Receptor Signaling Platforms: The Receptor Tyrosine Kinase-G Protein-Coupled Receptor Signaling Complex; 5.1. Introduction; 5.2. Lysophospholipid Receptor-Receptor Tyrosine Kinase Complexes; 5.3. Other Lysophospholipid Receptor Signaling Platforms; 5.4. Other Examples of RTK-GPCR Signaling Platforms 5.5. Interaction of RGS Proteins with Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes5.6. S1P and RTK Transactivation; 5.7. Approaches for the Study of Receptor Tyrosine Kinase-Lysophospholipid Receptor Signaling Complexes; 5.8. Some Useful Protocols for Studying RTK-Lysophospholipid Receptor Signaling Platforms; 5.8.1. Compounds; 5.8.2. Cells; 5.8.3. Immunoprecipitation; 5.8.4. Immunofluorescence; 5.8.5. GTP-γ-S Binding Assay; 5.8.6. Cell Migration; 5.9. Conclusion; Acknowledgment; References CHAPTER 6: Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions |
Record Nr. | UNINA-9910808700503321 |
Hoboken, N.J., : Wiley, c2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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