Gluten and celiac disease |
Pubbl/distr/stampa | [Bethesda, Md.] : , : NIH, U.S. National Library of Medicine, , 2017 |
Descrizione fisica | 1 online resource (1 video file (3 min., 00 sec.)) : sound, color |
Soggetto topico |
Celiac disease
Celiac disease - Diagnosis Gluten-free diet - Health aspects |
Soggetto genere / forma |
Internet videos.
Video recordings. |
Formato | Videoregistrazioni ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | MedlinePlus: trusted health information for you |
Record Nr. | UNINA-9910713782203321 |
[Bethesda, Md.] : , : NIH, U.S. National Library of Medicine, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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Refractory celiac disease / / Georgia Malamut and Nadine Cerf-Bensussan, editors |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer International Publishing, , [2022] |
Descrizione fisica | 1 online resource (149 pages) |
Disciplina | 616.399 |
Soggetto topico |
Celiac disease
Celiac disease - Diagnosis |
ISBN | 3-030-90142-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Contents -- Introduction -- References -- Uncomplicated Celiac Disease -- Introduction -- Epidemiology -- Pathogenesis and Risk Factors -- Clinical Presentation -- Physical Examination Findings -- Diagnosis of Celiac Disease -- Video Capsule Endoscopy and Enteroscopy in Celiac Disease -- Follow-Up of Celiac Disease -- Conclusion -- References -- Mechanisms of Lymphomagenesis in Celiac Disease: Lessons for Therapy -- Introduction -- The Long History of Intestinal Lymphoma in Celiac Disease -- The Intraepithelial Origin of Lymphoma Complicating Celiac Disease -- Analysis of the Transition from Uncomplicated CeD to Type 1 and Type 2 Refractory CeD and EATL -- Identification of the Intraepithelial Precursor(s) of RCD2 Lymphocytes from a Subset of Innate-like iCD3+ IEL (Fig. 1) -- JAK1-STAT3 Mutations in RCD2 Link Chronic Inflammation and Lymphomagenesis (Fig. 2) -- EATL Complicating RCD2 or Occurring De Novo in Celiac Disease or RCD1 Share a Mutational Landscape Dominated by JAK1 and STAT3 Mutations (Fig. 2) -- Lessons for Therapy in RCD2 -- Conclusion and Perspectives -- References -- From Unresponsive Celiac Disease to Refractory Celiac Disease: Epidemiological Data -- Introduction -- The Problems with Investigating Compliance -- Mucosal Healing and Outcome -- Epidemiology of RCD1 -- Epidemiology of RCD2 -- Concluding Remarks -- References -- The Role of Endoscopy in Refractory Coeliac Disease -- Introduction -- Upper GI Endoscopy -- Small Bowel Capsule Endoscopy -- Device Assisted Enteroscopy -- Which Patients Should Undergo Endoscopy? -- Conclusions -- References -- The Role of Pathologist in the Diagnosis of Refractory Coeliac Disease-and Enteropathy-Associated T Cell Lymphoma -- Introduction -- Refractory Coeliac Disease (RCD) Diagnosis -- Type 1 RCD (RCD1) -- Type 2 RCD (RCD2) -- Ulcerative Jejunoileitis.
Enteropathy-Associated T-Cell Lymphoma (EATL) -- Conclusion -- References -- Laboratory Findings for the Diagnosis of Celiac Disease Related Complications -- Introduction -- Immunophenotypic Characteristics -- Phenotypical Characteristics of Intestinal Lymphocytes in the Normal Human Intestine, in CD and in RCD. Application for Diagnosis by Flow Cytometry -- Technical Aspects for Flow Immunophenotyping of Duodenal Biopsies -- Value of Flow-Cytometry in the Diagnostic Work-Up: Advantages and Limitations -- Genetic Characteristics of RCDII and EATL. Application for Diagnosis -- Immunogenetic Features: Clonality Assessment -- Rationale -- Clonality Assessment in Clinical Practice and Technical Considerations -- Future Developments -- Oncogenetic Features -- Cytogenetics -- Gene Sequencing -- Rationale -- Molecular Abnormalities in RCD and EATL -- JAK-STAT Pathway -- Other Genes Mutations -- Lessons from the VAFs -- Clinical Significance -- Technical Aspects -- Conclusion and Perspectives -- References -- The Other Causes of Severe Enteropathy with Villous Atrophy Non-Responsive to a Gluten-Free Diet -- Environmental Enteropathy -- Autoimmune Enteropathy -- Common Variable Immunodeficiency Enteropathy -- Lymphoproliferative Disorders -- Drug/Iatrogenic Enteropathy -- Angiotensin Receptor Blockers -- Non-steroidal Anti-Inflammatories -- Mycophenolate Mofetil -- Methotrexate -- Azathioprine -- Monoclonal Antibodies -- Graft-Versus-Host Disease -- Chemotherapy -- Radiation -- Infectious Enteropathy -- Giardiasis -- Whipple's Disease -- Human Immunodeficiency Virus -- Tropical Sprue -- Small Intestinal Bacterial Overgrowth -- Collagenous Sprue -- Eosinophilic Gastroenteritis -- References -- Treatment of Refractory Celiac Disease -- Introduction -- Overview of the Drugs Investigated in Refractory Celiac Disease -- Immunosuppressive and Immunomodulatory Drugs. Systemic Corticosteroids and Budesonide -- Cyclosporin -- Thiopurines -- IL-10 -- Anti-TNF -- Mesalamine -- Cytoreductive Drugs -- Alemtuzumab -- Cladribine -- Stem Cell Transplantation -- Mesenchymal Stem Cell Transplantation -- Novel Approaches -- Conclusion -- Looking Back and Looking Forward: Future Perspectives on Treatment of Refractory Celiac Disease -- References -- Prognosis of Refractory Coeliac Disease: The Prognostic Scores -- Introduction -- Defining Complicated Coeliac Disease -- Mortality in Complicated Coeliac Disease and Refractory Coeliac Disease -- Predictors and Risk Factors for Complicated Coeliac Disease -- Prognostic Score for Complicated Coeliac Disease: The PROCONSUL SCORE -- Predictors and Risk Factors for Poor Outcomes in Refractory Coeliac Disease -- Clinical and Molecular Classification of Refractory Coeliac Disease -- Scores to Predict Survival in Refractory Coeliac Disease -- Conclusions -- References -- Enteropathy-Associated T-Cell Lymphoma -- Definition -- Epidemiology -- Pathology and Genetics -- Clinical Features -- Staging -- Prognosis -- Treatment -- Conclusion and Perspective -- References. |
Record Nr. | UNINA-9910556881403321 |
Cham, Switzerland : , : Springer International Publishing, , [2022] | ||
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Lo trovi qui: Univ. Federico II | ||
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