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Endocannabinoids / / edited by Loren Parsons, Matthew Hill
| Endocannabinoids / / edited by Loren Parsons, Matthew Hill |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Amsterdam : , : Elsevier Science, , 2015 |
| Descrizione fisica | 1 online resource (368 p.) |
| Collana | International review of neurobiology |
| Soggetto topico |
Cannabinoids
Cannabinoids - Receptors Cannabinoids - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-12-801278-1
0-12-801376-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Endocannabinoids; Copyright; Contents; Contributors; Preface; Chapter One: The Endocannabinoid Signaling System in the CNS: A Primer; 1. Introduction; 2. The Endocannabinoids; 2.1. Definitions; 2.2. Mechanisms of AEA Biosynthesis; 2.2.1. Precursor Synthesis; 2.2.2. NAPE Conversion to NAE: NAPE-PLD; 2.2.3. NAPE Conversion to NAE: Multienzyme Pathways; 2.2.4. AEA Synthesis from AA; 2.2.5. Summary; 2.3. Mechanisms of AEA Hydrolysis; 2.3.1. Fatty Acid Amide Hydrolase; 2.3.2. NAE-Hydrolyzing Acid Amidase: A Peripheral AEA Hydrolase; 2.4. Mechanisms of 2-AG Biosynthesis
2.4.1. Diacylglycerol Lipase2.4.2. Mechanisms of DAG Synthesis; 2.5. Mechanisms of 2-AG Catabolism; 2.5.1. Monoacylglycerol Lipase; 2.5.2. Other Enzymes that Hydrolyze 2-AG in the Brain; 2.5.3. Contribution of 2-AG to AA Concentrations; 2.6. Other Inactivation Mechanisms for AEA and 2-AG; 2.6.1. Uptake, Accumulation, and Sequestration; 2.6.2. Oxygenation of the Arachidonate Backbone; 3. Endocannabinoid Receptors; 3.1. Introduction; 3.2. CB1 Cannabinoid Receptors; 3.2.1. CB1R Signaling; 3.2.2. CB1R Pharmacology; 4. CB1R and Retrograde Regulation of Synaptic Activity; 4.1. The Basic Paradigms 4.1.1. Short-Term Depression of Synaptic Transmission4.1.2. Long-Term Depression of Transmission; 5. Summary; Acknowledgments; References; Chapter Two: Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and E ...; 1. Adolescence and Pubertal Maturation; 2. The Neurobiology of Stress; 3. Adolescent HPA Axis Development; 4. The Developmental Influence of Gonadal Hormones on the HPA Axis; 5. The Endocannabinoid System; 6. Endocannabinoid System Regulation of the HPA Axis in Adulthood; 7. Ontogeny of the Endocannabinoid System 8. Adolescent HPA Axis Function: A Regulatory Role for the Endocannabinoid System?8.1. Adolescent Stress Exposure Modulates Corticolimbic Endocannabinoid Signaling; 8.2. Adolescent Cannabinoid Exposure Modifies Adult Stress-Induced HPA Axis Activity; 8.3. Long-Term Consequences of Adolescent Endocannabinoid System Dysregulation on the Developing Brain and Behavior; 9. Concluding Remarks; Acknowledgments; References; Chapter Three: The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestin...; 1. Introduction 2. The Enteric Nervous System and the Brain-Gut Axis2.1. The Structure of the ENS; 3. The Endocannabinoid System; 3.1. Cannabinoid Receptors and Their Ligands; 3.2. Cannabinoid Receptors in the ENS; 3.3. Endocannabinoid Synthesis; 3.4. 2-AG Synthesis and Degradation; 3.5. Anandamide Synthesis and Degradation; 4. Endocannabinoid Signaling Mechanisms; 4.1. Endocannabinoid Transport Mechanisms; 5. Other Receptors, Agonists, and Antagonists; 5.1. Phytocannabinoids; 5.2. Peptide Endocannabinoids; 5.3. Transient Receptor Potential Vanilloid 1; 5.4. Virodhamine, an Endogenous CB1 Antagonist 5.5. G Protein-Coupled Receptor 55 |
| Record Nr. | UNINA-9910460735003321 |
| Amsterdam : , : Elsevier Science, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Endocannabinoids / / edited by Loren Parsons, Matthew Hill
| Endocannabinoids / / edited by Loren Parsons, Matthew Hill |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Amsterdam : , : Elsevier Science, , 2015 |
| Descrizione fisica | 1 online resource (368 p.) |
| Collana | International review of neurobiology |
| Soggetto topico |
Cannabinoids
Cannabinoids - Receptors Cannabinoids - Physiological effect |
| ISBN |
0-12-801278-1
0-12-801376-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Endocannabinoids; Copyright; Contents; Contributors; Preface; Chapter One: The Endocannabinoid Signaling System in the CNS: A Primer; 1. Introduction; 2. The Endocannabinoids; 2.1. Definitions; 2.2. Mechanisms of AEA Biosynthesis; 2.2.1. Precursor Synthesis; 2.2.2. NAPE Conversion to NAE: NAPE-PLD; 2.2.3. NAPE Conversion to NAE: Multienzyme Pathways; 2.2.4. AEA Synthesis from AA; 2.2.5. Summary; 2.3. Mechanisms of AEA Hydrolysis; 2.3.1. Fatty Acid Amide Hydrolase; 2.3.2. NAE-Hydrolyzing Acid Amidase: A Peripheral AEA Hydrolase; 2.4. Mechanisms of 2-AG Biosynthesis
2.4.1. Diacylglycerol Lipase2.4.2. Mechanisms of DAG Synthesis; 2.5. Mechanisms of 2-AG Catabolism; 2.5.1. Monoacylglycerol Lipase; 2.5.2. Other Enzymes that Hydrolyze 2-AG in the Brain; 2.5.3. Contribution of 2-AG to AA Concentrations; 2.6. Other Inactivation Mechanisms for AEA and 2-AG; 2.6.1. Uptake, Accumulation, and Sequestration; 2.6.2. Oxygenation of the Arachidonate Backbone; 3. Endocannabinoid Receptors; 3.1. Introduction; 3.2. CB1 Cannabinoid Receptors; 3.2.1. CB1R Signaling; 3.2.2. CB1R Pharmacology; 4. CB1R and Retrograde Regulation of Synaptic Activity; 4.1. The Basic Paradigms 4.1.1. Short-Term Depression of Synaptic Transmission4.1.2. Long-Term Depression of Transmission; 5. Summary; Acknowledgments; References; Chapter Two: Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and E ...; 1. Adolescence and Pubertal Maturation; 2. The Neurobiology of Stress; 3. Adolescent HPA Axis Development; 4. The Developmental Influence of Gonadal Hormones on the HPA Axis; 5. The Endocannabinoid System; 6. Endocannabinoid System Regulation of the HPA Axis in Adulthood; 7. Ontogeny of the Endocannabinoid System 8. Adolescent HPA Axis Function: A Regulatory Role for the Endocannabinoid System?8.1. Adolescent Stress Exposure Modulates Corticolimbic Endocannabinoid Signaling; 8.2. Adolescent Cannabinoid Exposure Modifies Adult Stress-Induced HPA Axis Activity; 8.3. Long-Term Consequences of Adolescent Endocannabinoid System Dysregulation on the Developing Brain and Behavior; 9. Concluding Remarks; Acknowledgments; References; Chapter Three: The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestin...; 1. Introduction 2. The Enteric Nervous System and the Brain-Gut Axis2.1. The Structure of the ENS; 3. The Endocannabinoid System; 3.1. Cannabinoid Receptors and Their Ligands; 3.2. Cannabinoid Receptors in the ENS; 3.3. Endocannabinoid Synthesis; 3.4. 2-AG Synthesis and Degradation; 3.5. Anandamide Synthesis and Degradation; 4. Endocannabinoid Signaling Mechanisms; 4.1. Endocannabinoid Transport Mechanisms; 5. Other Receptors, Agonists, and Antagonists; 5.1. Phytocannabinoids; 5.2. Peptide Endocannabinoids; 5.3. Transient Receptor Potential Vanilloid 1; 5.4. Virodhamine, an Endogenous CB1 Antagonist 5.5. G Protein-Coupled Receptor 55 |
| Record Nr. | UNINA-9910797822103321 |
| Amsterdam : , : Elsevier Science, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Endocannabinoids / / edited by Loren Parsons, Matthew Hill
| Endocannabinoids / / edited by Loren Parsons, Matthew Hill |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Amsterdam : , : Elsevier Science, , 2015 |
| Descrizione fisica | 1 online resource (368 p.) |
| Collana | International review of neurobiology |
| Soggetto topico |
Cannabinoids
Cannabinoids - Receptors Cannabinoids - Physiological effect |
| ISBN |
0-12-801278-1
0-12-801376-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Endocannabinoids; Copyright; Contents; Contributors; Preface; Chapter One: The Endocannabinoid Signaling System in the CNS: A Primer; 1. Introduction; 2. The Endocannabinoids; 2.1. Definitions; 2.2. Mechanisms of AEA Biosynthesis; 2.2.1. Precursor Synthesis; 2.2.2. NAPE Conversion to NAE: NAPE-PLD; 2.2.3. NAPE Conversion to NAE: Multienzyme Pathways; 2.2.4. AEA Synthesis from AA; 2.2.5. Summary; 2.3. Mechanisms of AEA Hydrolysis; 2.3.1. Fatty Acid Amide Hydrolase; 2.3.2. NAE-Hydrolyzing Acid Amidase: A Peripheral AEA Hydrolase; 2.4. Mechanisms of 2-AG Biosynthesis
2.4.1. Diacylglycerol Lipase2.4.2. Mechanisms of DAG Synthesis; 2.5. Mechanisms of 2-AG Catabolism; 2.5.1. Monoacylglycerol Lipase; 2.5.2. Other Enzymes that Hydrolyze 2-AG in the Brain; 2.5.3. Contribution of 2-AG to AA Concentrations; 2.6. Other Inactivation Mechanisms for AEA and 2-AG; 2.6.1. Uptake, Accumulation, and Sequestration; 2.6.2. Oxygenation of the Arachidonate Backbone; 3. Endocannabinoid Receptors; 3.1. Introduction; 3.2. CB1 Cannabinoid Receptors; 3.2.1. CB1R Signaling; 3.2.2. CB1R Pharmacology; 4. CB1R and Retrograde Regulation of Synaptic Activity; 4.1. The Basic Paradigms 4.1.1. Short-Term Depression of Synaptic Transmission4.1.2. Long-Term Depression of Transmission; 5. Summary; Acknowledgments; References; Chapter Two: Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and E ...; 1. Adolescence and Pubertal Maturation; 2. The Neurobiology of Stress; 3. Adolescent HPA Axis Development; 4. The Developmental Influence of Gonadal Hormones on the HPA Axis; 5. The Endocannabinoid System; 6. Endocannabinoid System Regulation of the HPA Axis in Adulthood; 7. Ontogeny of the Endocannabinoid System 8. Adolescent HPA Axis Function: A Regulatory Role for the Endocannabinoid System?8.1. Adolescent Stress Exposure Modulates Corticolimbic Endocannabinoid Signaling; 8.2. Adolescent Cannabinoid Exposure Modifies Adult Stress-Induced HPA Axis Activity; 8.3. Long-Term Consequences of Adolescent Endocannabinoid System Dysregulation on the Developing Brain and Behavior; 9. Concluding Remarks; Acknowledgments; References; Chapter Three: The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestin...; 1. Introduction 2. The Enteric Nervous System and the Brain-Gut Axis2.1. The Structure of the ENS; 3. The Endocannabinoid System; 3.1. Cannabinoid Receptors and Their Ligands; 3.2. Cannabinoid Receptors in the ENS; 3.3. Endocannabinoid Synthesis; 3.4. 2-AG Synthesis and Degradation; 3.5. Anandamide Synthesis and Degradation; 4. Endocannabinoid Signaling Mechanisms; 4.1. Endocannabinoid Transport Mechanisms; 5. Other Receptors, Agonists, and Antagonists; 5.1. Phytocannabinoids; 5.2. Peptide Endocannabinoids; 5.3. Transient Receptor Potential Vanilloid 1; 5.4. Virodhamine, an Endogenous CB1 Antagonist 5.5. G Protein-Coupled Receptor 55 |
| Record Nr. | UNINA-9910818525803321 |
| Amsterdam : , : Elsevier Science, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Endocannabinoids : molecular, pharmacological, behavioral and clinical features / / editor, Eric Murillo-Rodr©iguez; co-editors, Emmanuel S. Onaivi, Nissar A. Darmani, Edward Wagner
| Endocannabinoids : molecular, pharmacological, behavioral and clinical features / / editor, Eric Murillo-Rodr©iguez; co-editors, Emmanuel S. Onaivi, Nissar A. Darmani, Edward Wagner |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2013] |
| Descrizione fisica | 1 online resource (223 p.) |
| Disciplina | 615.7827 |
| Altri autori (Persone) |
DarmaniNissar A
Murillo-Rodr©iguezEric OnaiviEmmanuel S WagnerEdward |
| Soggetto topico |
Cannabinoids - Physiological effect
Cannabinoids - Receptors |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60805-028-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; TItle; EUL; Contents; About the ebook; Foreword; Preface; List of Contributors; Part 1; Chapter 01; Chapter 02; Chapter 03; Part II; Chapter 04; Chapter 05; Chapter 06; Index |
| Record Nr. | UNINA-9910462985803321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2013] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Endocannabinoids : molecular, pharmacological, behavioral and clinical features / / editor, Eric Murillo-Rodr©iguez; co-editors, Emmanuel S. Onaivi, Nissar A. Darmani, Edward Wagner
| Endocannabinoids : molecular, pharmacological, behavioral and clinical features / / editor, Eric Murillo-Rodr©iguez; co-editors, Emmanuel S. Onaivi, Nissar A. Darmani, Edward Wagner |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2013] |
| Descrizione fisica | 1 online resource (223 p.) |
| Disciplina | 615.7827 |
| Altri autori (Persone) |
DarmaniNissar A
Murillo-Rodr©iguezEric OnaiviEmmanuel S WagnerEdward |
| Soggetto topico |
Cannabinoids - Physiological effect
Cannabinoids - Receptors |
| ISBN | 1-60805-028-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; TItle; EUL; Contents; About the ebook; Foreword; Preface; List of Contributors; Part 1; Chapter 01; Chapter 02; Chapter 03; Part II; Chapter 04; Chapter 05; Chapter 06; Index |
| Record Nr. | UNINA-9910787504903321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2013] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Endocannabinoids : molecular, pharmacological, behavioral and clinical features / / editor, Eric Murillo-Rodr©iguez; co-editors, Emmanuel S. Onaivi, Nissar A. Darmani, Edward Wagner
| Endocannabinoids : molecular, pharmacological, behavioral and clinical features / / editor, Eric Murillo-Rodr©iguez; co-editors, Emmanuel S. Onaivi, Nissar A. Darmani, Edward Wagner |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2013] |
| Descrizione fisica | 1 online resource (223 p.) |
| Disciplina | 615.7827 |
| Altri autori (Persone) |
DarmaniNissar A
Murillo-Rodr©iguezEric OnaiviEmmanuel S WagnerEdward |
| Soggetto topico |
Cannabinoids - Physiological effect
Cannabinoids - Receptors |
| ISBN | 1-60805-028-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; TItle; EUL; Contents; About the ebook; Foreword; Preface; List of Contributors; Part 1; Chapter 01; Chapter 02; Chapter 03; Part II; Chapter 04; Chapter 05; Chapter 06; Index |
| Record Nr. | UNINA-9910821130803321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2013] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
