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Biological Mechanisms of Minimal Residual Disease and Systemic Cancer / / edited by Julio A. Aguirre-Ghiso
Biological Mechanisms of Minimal Residual Disease and Systemic Cancer / / edited by Julio A. Aguirre-Ghiso
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (165 pages)
Disciplina 616.994071
Collana Advances in Experimental Medicine and Biology
Soggetto topico Cancer - Research
Human genetics
Molecular biology
Cytology
Drug resistance
Cancer - Molecular aspects
Human Genetics
Molecular Medicine
Cell Biology
Drug Resistance, Neoplasm
ISBN 3-319-97746-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Foreword. Understanding and targeting minimal residual disease: a path to change cancer patient outcomes -- Epigenetics and Pluripotency Aspects of Disseminated Cancer Cells during Minimal Residual Disease -- Anti-angiogenic therapy-mediated endothelial damage: A driver of breast cancer recurrence?- Minimal Residual Disease in Prostate Cancer -- Minimal Residual Disease in Head and Neck Cancer and Esophageal Cancer -- Detection of Minimal Residual Disease and its Clinical Applications in Melanoma and Breast Cancer Patients Selena -- Preservation of Quiescent Chronic Myelogenous Leukemia Stem Cells by the Bone Marrow Microenvironment.-Minimal Residual Disease in Acute Myeloid leukemia -- Characteristics and therapeutic targeting of minimal residual disease in childhood acute lymphoblastic leukemia -- Minimal Residual Disease in Multiple Myeloma: Impact on response assessment, prognosis and tumor heterogeneity -- Index. .
Record Nr. UNINA-9910298411703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Materiale a stampa
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Cancer : from Genomics to Pharmaceutics
Cancer : from Genomics to Pharmaceutics
Autore Karakas Zeynep
Edizione [1st ed.]
Pubbl/distr/stampa Istanbul, Turkiye : , : Istanbul University Press, , 2024
Descrizione fisica 1 online resource (311 pages)
Altri autori (Persone) ErdalMeryem Sedef
SayitogluMuge
Soluk TekkesinMerva
Soggetto topico Cancer - Genetic aspects
Cancer - Molecular aspects
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FOREWORD -- PREFACE -- ACKNOWLEDGEMENTS -- [-5pt][0.3ex] NEW GENOMIC ERA: WHAT WE HAVE LEARNED FROM THE CANCER GENOME?[0.2ex] Eda SUN, Müge SAYİTOĞLU -- [-5pt][0.3ex] CANCER EVOLUTION: FROM MULTISTEP CARCINOGENESIS TO CHROMOTHRIPSIS[0.2ex] Khusan KHODZHAEV, Özden HATIRNAZ -- [-5pt][0.3ex] EXOSOMES IN CANCER DEVELOPMENT AND METASTASIS[0.2ex] Merve Çiğdem ÖZGEL, Şeref Buğra TUNÇER -- [-5pt][0.3ex] METHYLATION BIOMARKERS AND LIQUID BIOPSY STUDIES IN CANCER[0.2ex] Seval TURNA, Semra DEMOKAN -- [-5pt][0.3ex] THE ROLE OF MIRNAS IN CONTROL OF K-RAS GENE EXPRESSION[0.2ex] Büşra KURT GÜLTAŞLAR, Ebru Esin YÖRÜKER -- [-5pt][0.3ex] GERMLINE PREDISPOSITION TO CHILDHOOD CANCERS[0.2ex] Tuğçe SUDUTAN, Yücel ERBİLGİN -- [-5pt][0.3ex] BIG DATA / MULTIOMIC APPROACHES IN CANCER RESEARCH[0.2ex] Seda SÜSGÜN, Barış SALMAN, Sibel Aylin UĞUR İŞERİ -- [-5pt][0.3ex] NEW THERAPEUTIC APPROACHES IN GENOME[0.2ex] İldeniz USLU- BIÇAK, Büşra YAŞA-ÇEVİK, Selçuk SÖZER TOKDEMİR -- [-5pt][0.3ex] TARGETING STRATEGIES WITH NEW DRUG DELIVERY SYSTEMS IN CANCER THERAPY[0.2ex] Yavuz Selim ÇELİK, Burcu MESUT, Yıldız ÖZSOY -- [-5pt][0.3ex] CURRENT ADVANCES IN MEDICINAL CHEMISTRY OF ANTICANCER AGENTS[0.2ex] Efe Doğukan DİNCEL, Nuray ULUSOY GÜZELDEMİRCİ -- [-5pt][0.3ex] THE ROLE OF PHARMACOGENOMICS IN CHEMOTHERAPEUTIC SUSCEPTIBILITY AND TOXICITY[0.2ex] Özge Sultan ZENGİN, Mahmoud ABUDAYYAK, Gül ÖZHAN
Altri titoli varianti Cancer
Record Nr. UNINA-9910897782903321
Karakas Zeynep  
Istanbul, Turkiye : , : Istanbul University Press, , 2024
Materiale a stampa
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Cancer . Primer of the molecular biology of cancer : principles & practice of oncology / / editors, Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg
Cancer . Primer of the molecular biology of cancer : principles & practice of oncology / / editors, Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg
Edizione [Third edition.]
Pubbl/distr/stampa Philadelphia : , : Wolters Kluwer, , [2021]
Descrizione fisica 1 online resource (1011 pages)
Disciplina 616.994
Soggetto topico Cancer - Molecular aspects
Cancer - Genetic aspects
Neoplasms - genetics
ISBN 1-9751-4913-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910795673203321
Philadelphia : , : Wolters Kluwer, , [2021]
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Cancer cell signalling / / edited by Amanda Harvey
Cancer cell signalling / / edited by Amanda Harvey
Pubbl/distr/stampa Chichester, West Sussex : , : John Wiley & Sons, Inc., , 2013
Descrizione fisica 1 online resource (230 p.)
Disciplina 616.99/4
Altri autori (Persone) HarveyAmanda <1970->
Soggetto topico Cancer - Molecular aspects
Carcinogenesis
Soggetto genere / forma Electronic books.
ISBN 1-119-96756-2
1-118-52775-5
1-118-52782-8
1-118-52783-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Epidermal growth factor receptor family / Amanda Harvey -- Insulin and the insulin-like growth factor (IGF) family / Maria Thorpe, Erald Shehu, and Amanda Harvey -- Transforming growth factor-[beta] receptor signalling / Gudrun Stenbeck -- Wnt signalling / David Tree -- Mammalian target of rapamycin (mTOR) signalling / Maria Thorpe and Emmanouil Karteris -- c-Met receptor signalling / Stephen Hiscox -- Vascular endothelial growth factor and its receptor family / Katarzyna Leszczynska, Christopher Hillyar, and Ester M. Hammond -- Progesterone receptor signalling in breast cancer models / Andrea R. Daniel, Todd P. Knutson, Christy R. Hagan, and Carol A. Lange -- Signalling cross-talk / Amanda Harvey.
Record Nr. UNINA-9910452263203321
Chichester, West Sussex : , : John Wiley & Sons, Inc., , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Cancer cell signalling / / edited by Amanda Harvey
Cancer cell signalling / / edited by Amanda Harvey
Pubbl/distr/stampa Chichester, West Sussex : , : John Wiley & Sons, Inc., , 2013
Descrizione fisica 1 online resource (230 p.)
Disciplina 616.99/4
Altri autori (Persone) HarveyAmanda <1970->
Soggetto topico Cancer - Molecular aspects
Carcinogenesis
ISBN 1-119-96756-2
1-118-52775-5
1-118-52782-8
1-118-52783-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Epidermal growth factor receptor family / Amanda Harvey -- Insulin and the insulin-like growth factor (IGF) family / Maria Thorpe, Erald Shehu, and Amanda Harvey -- Transforming growth factor-[beta] receptor signalling / Gudrun Stenbeck -- Wnt signalling / David Tree -- Mammalian target of rapamycin (mTOR) signalling / Maria Thorpe and Emmanouil Karteris -- c-Met receptor signalling / Stephen Hiscox -- Vascular endothelial growth factor and its receptor family / Katarzyna Leszczynska, Christopher Hillyar, and Ester M. Hammond -- Progesterone receptor signalling in breast cancer models / Andrea R. Daniel, Todd P. Knutson, Christy R. Hagan, and Carol A. Lange -- Signalling cross-talk / Amanda Harvey.
Record Nr. UNINA-9910790545703321
Chichester, West Sussex : , : John Wiley & Sons, Inc., , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cancer cell signalling / / edited by Amanda Harvey
Cancer cell signalling / / edited by Amanda Harvey
Edizione [1st ed.]
Pubbl/distr/stampa Chichester, West Sussex : , : John Wiley & Sons, Inc., , 2013
Descrizione fisica 1 online resource (230 p.)
Disciplina 616.99/4
Altri autori (Persone) HarveyAmanda <1970->
Soggetto topico Cancer - Molecular aspects
Carcinogenesis
ISBN 9781119967569
1119967562
9781118527757
1118527755
9781118527825
1118527828
9781118527832
1118527836
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Epidermal growth factor receptor family / Amanda Harvey -- Insulin and the insulin-like growth factor (IGF) family / Maria Thorpe, Erald Shehu, and Amanda Harvey -- Transforming growth factor-[beta] receptor signalling / Gudrun Stenbeck -- Wnt signalling / David Tree -- Mammalian target of rapamycin (mTOR) signalling / Maria Thorpe and Emmanouil Karteris -- c-Met receptor signalling / Stephen Hiscox -- Vascular endothelial growth factor and its receptor family / Katarzyna Leszczynska, Christopher Hillyar, and Ester M. Hammond -- Progesterone receptor signalling in breast cancer models / Andrea R. Daniel, Todd P. Knutson, Christy R. Hagan, and Carol A. Lange -- Signalling cross-talk / Amanda Harvey.
Record Nr. UNINA-9910955863803321
Chichester, West Sussex : , : John Wiley & Sons, Inc., , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The cancer degradome [[electronic resource] ] : proteases and cancer biology / / edited by Dylan Edwards ... [et al.]
The cancer degradome [[electronic resource] ] : proteases and cancer biology / / edited by Dylan Edwards ... [et al.]
Edizione [1st ed. 2008.]
Pubbl/distr/stampa New York, : Springer, c2008
Descrizione fisica 1 online resource (946 p.)
Disciplina 616.994
Altri autori (Persone) EdwardsDylan R
Soggetto topico Cancer - Molecular aspects
Proteolytic enzymes
Soggetto genere / forma Electronic books.
ISBN 1-281-79189-X
9786611791896
0-387-69057-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto The Degradome and Its Analysis -- Protease Genomics and the Cancer Degradome -- The CLIP-CHIP™: A Focused Oligonucleotide Microarray Platform for Transcriptome Analysis of the Complete Human and Murine Cancer Degradomes -- The Hu/Mu ProtIn Chip: A Custom Dual-Species Oligonucleotide Microarray for Profiling Degradome Gene Expression in Tumors and Their Microenvironment -- Quantitative Real-Time PCR Analysis of Degradome Gene Expression -- Identification of Protease Substrates by Mass Spectrometry Approaches-1 -- Identification of Protease Substrates by Mass Spectrometry Approaches-2 -- Activity-Based Imaging and Biochemical Profiling Tools for Analysis of the Cancer Degradome -- Images of Cleavage: Tumor Proteases in Action -- Insights into Protease Function -- Proteolytic Pathways: Intersecting Cascades in Cancer Development -- Physiological Functions of Plasminogen Activation: Effects of Gene Deficiencies in Humans and Mice -- The Plasminogen Activation System in Tissue Remodeling and Cancer Invasion -- The Urokinase Plasminogen Activator Receptor as a Target for Cancer Therapy -- The Endocytic Collagen Receptor, uPARAP/Endo180, in Cancer Invasion and Tissue Remodeling -- Physiological and Pathological Functions of Type II Transmembrane Serine Proteases: Lessons from Transgenic Mouse Models and Human Disease-Associated Mutations -- Roles of Cysteine Proteases in Tumor Progression: Analysis of Cysteine Cathepsin Knockout Mice in Cancer Models -- In Vitro and In Vivo Models of Angiogenesis to Dissect MMP Functions -- The Surface Transplantation Model to Study the Tumor–Host Interface -- Unravelling the Roles of Proteinases in Cell Migration In Vitro and In Vivo -- New Insights into MMP function in Adipogenesis -- TIMPs: Extracellular Modifiers in Cancer Development -- The Interface Between Proteolysis and Cell Signalling -- Invadopodia: Interface for Invasion -- uPAR and Proteases in Mobilization of Hematopoietic Stem Cells -- The Urokinase Receptor and Integrins Constitute a Cell Migration Signalosome -- Measuring uPAR Dynamics in Live Cells -- Janus-Faced Effects of Broad-Spectrum and Specific MMP Inhibition on Metastasis -- Cytokine Substrates: MMP Regulation of Inflammatory Signaling Molecules -- Matrix Metalloproteinases as Key Regulators of Tumor–Bone Interaction -- The Degradome as Source of Cancer Diagnostic and Markers -- The Plasminogen Activation System as a Source of Prognostic Markers in Cancer -- Cysteine Cathepsins and Cystatins as Cancer Biomarkers -- Novel Degradome Markers in Breast Cancer -- Meta-Analysis of Gene Expression Microarray Data: Degradome Genes in Healthy and Cancer Tissues -- Degradome Gene Polymorphisms -- TIMP-1 as a Prognostic Marker in Colorectal Cancer -- Novel Therapeutic Strategies -- Structure and Inhibition of the Urokinase-Type Plasminogen Activator Receptor -- Engineered Antagonists of uPA and PAI-1 -- MMP Inhibitor Clinical Trials – The Past, Present, and Future -- Tailoring TIMPs for Selective Metalloproteinase Inhibition -- Third-Generation MMP Inhibitors: Recent Advances in the Development of Highly Selective Inhibitors -- Protease-Activated Delivery and Imaging Systems -- Development of Tumour-Selective and Endoprotease-Activated Anticancer Therapeutics -- Targeting Degradome Genes via Engineered Viral Vectors.
Record Nr. UNINA-9910451695603321
New York, : Springer, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The cancer degradome [[electronic resource] ] : proteases and cancer biology / / edited by Dylan Edwards ... [et al.]
The cancer degradome [[electronic resource] ] : proteases and cancer biology / / edited by Dylan Edwards ... [et al.]
Edizione [1st ed. 2008.]
Pubbl/distr/stampa New York, : Springer, c2008
Descrizione fisica 1 online resource (946 p.)
Disciplina 616.994
Altri autori (Persone) EdwardsDylan R
Soggetto topico Cancer - Molecular aspects
Proteolytic enzymes
ISBN 1-281-79189-X
9786611791896
0-387-69057-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto The Degradome and Its Analysis -- Protease Genomics and the Cancer Degradome -- The CLIP-CHIP™: A Focused Oligonucleotide Microarray Platform for Transcriptome Analysis of the Complete Human and Murine Cancer Degradomes -- The Hu/Mu ProtIn Chip: A Custom Dual-Species Oligonucleotide Microarray for Profiling Degradome Gene Expression in Tumors and Their Microenvironment -- Quantitative Real-Time PCR Analysis of Degradome Gene Expression -- Identification of Protease Substrates by Mass Spectrometry Approaches-1 -- Identification of Protease Substrates by Mass Spectrometry Approaches-2 -- Activity-Based Imaging and Biochemical Profiling Tools for Analysis of the Cancer Degradome -- Images of Cleavage: Tumor Proteases in Action -- Insights into Protease Function -- Proteolytic Pathways: Intersecting Cascades in Cancer Development -- Physiological Functions of Plasminogen Activation: Effects of Gene Deficiencies in Humans and Mice -- The Plasminogen Activation System in Tissue Remodeling and Cancer Invasion -- The Urokinase Plasminogen Activator Receptor as a Target for Cancer Therapy -- The Endocytic Collagen Receptor, uPARAP/Endo180, in Cancer Invasion and Tissue Remodeling -- Physiological and Pathological Functions of Type II Transmembrane Serine Proteases: Lessons from Transgenic Mouse Models and Human Disease-Associated Mutations -- Roles of Cysteine Proteases in Tumor Progression: Analysis of Cysteine Cathepsin Knockout Mice in Cancer Models -- In Vitro and In Vivo Models of Angiogenesis to Dissect MMP Functions -- The Surface Transplantation Model to Study the Tumor–Host Interface -- Unravelling the Roles of Proteinases in Cell Migration In Vitro and In Vivo -- New Insights into MMP function in Adipogenesis -- TIMPs: Extracellular Modifiers in Cancer Development -- The Interface Between Proteolysis and Cell Signalling -- Invadopodia: Interface for Invasion -- uPAR and Proteases in Mobilization of Hematopoietic Stem Cells -- The Urokinase Receptor and Integrins Constitute a Cell Migration Signalosome -- Measuring uPAR Dynamics in Live Cells -- Janus-Faced Effects of Broad-Spectrum and Specific MMP Inhibition on Metastasis -- Cytokine Substrates: MMP Regulation of Inflammatory Signaling Molecules -- Matrix Metalloproteinases as Key Regulators of Tumor–Bone Interaction -- The Degradome as Source of Cancer Diagnostic and Markers -- The Plasminogen Activation System as a Source of Prognostic Markers in Cancer -- Cysteine Cathepsins and Cystatins as Cancer Biomarkers -- Novel Degradome Markers in Breast Cancer -- Meta-Analysis of Gene Expression Microarray Data: Degradome Genes in Healthy and Cancer Tissues -- Degradome Gene Polymorphisms -- TIMP-1 as a Prognostic Marker in Colorectal Cancer -- Novel Therapeutic Strategies -- Structure and Inhibition of the Urokinase-Type Plasminogen Activator Receptor -- Engineered Antagonists of uPA and PAI-1 -- MMP Inhibitor Clinical Trials – The Past, Present, and Future -- Tailoring TIMPs for Selective Metalloproteinase Inhibition -- Third-Generation MMP Inhibitors: Recent Advances in the Development of Highly Selective Inhibitors -- Protease-Activated Delivery and Imaging Systems -- Development of Tumour-Selective and Endoprotease-Activated Anticancer Therapeutics -- Targeting Degradome Genes via Engineered Viral Vectors.
Record Nr. UNINA-9910782094903321
New York, : Springer, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Cancer metabolomics : methods and applications / / Shen Hu. Editor
Cancer metabolomics : methods and applications / / Shen Hu. Editor
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (317 pages) : illustrations
Disciplina 616.994
Collana Advances in Experimental Medicine and Biology
Soggetto topico Cell metabolism
Metabolites
Cancer - Molecular aspects
Càncer
Metabolisme cel·lular
Soggetto genere / forma Llibres electrònics
ISBN 3-030-51652-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910483495703321
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cancer therapeutic targets / / edited by John L. Marshall
Cancer therapeutic targets / / edited by John L. Marshall
Edizione [1st ed. 2017.]
Pubbl/distr/stampa New York : , : Springer, , [2017]
Descrizione fisica 1 online resource (51 illus., 42 illus. in color. eReference.)
Disciplina 616.994
Soggetto topico Cancer - Molecular aspects
Cancer - Genetic aspects
Cancer - Treatment
ISBN 1-4419-0717-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto AKT -- Anti-4-1BB/4-1BBL -- Anti-B7-H4 -- Anti-CD40/Anti CD40L -- Anti-Idiotype antibodies -- Anti-Programmed Death 1 (PD1) -- B7.1 -- Bacterial Vaccines -- Brachyury -- CCL21 -- CD4+ T Cells -- CD8 T Cells -- CEA -- CTLA-4 -- Dendritic cells -- DNA Vaccines -- EGFR, Immunology -- Fc Gamma R -- Gangliosides -- Glucocorticoid-Induced TNF Receptor (GITR) -- GM-CSF and Whole Cells -- gp100 -- HER2/neu -- indoleamine 2,3-dioxygenase -- Integrins, Immunology -- Interferon alpha -- Interleukin 2 -- Interleukin 7 -- Interleukin 12 -- Interleukin 15 -- Interleukin 21 -- Lymphocyte Activation Gene 3 (LAG-3) -- MART-1 -- MUC1 -- NK Cells -- P53, Immunology -- PAP -- Peptide Vaccine: Overview -- Proteins (Mesothelin) -- PSA -- Survivin -- Telomerase-related proteins -- TGF Beta Receptors -- TLR7 and TLR8, Resiquimod, and 852A -- TLR9 -- Transforming Growth Factor β -- Tregs -- Tyrosinase: Overview -- VEGF -- Viral-Like Proteins -- Whole-Cell Vaccines -- FGF-FGFR Signaling in Cancer -- MMPs -- PDGF -- TIE -- VEGF A -- VEGF Ligands -- AXL -- B-Raf -- CKIT -- DNA Repair, Overview -- EGFR, Growth factors -- HER3 -- IGF 1 and IGF 2 -- Jak2/Stat5a/b Pathway in Prostate Cancer -- JNK Signaling in Diseases -- K-Ras -- MET -- NEDD9 -- N-Ras -- P38 -- Rac 1 -- Type I Insulin-Like Growth Factor Receptor -- Anti-apoptotic Bcl-2 -- BH3-Only Mimetics -- Caspase -- DR4 and DR5 -- FLIP -- MLH1 -- NF-κB -- PARP -- ROS -- X-Linked IAP -- APC -- AR, Overview -- BRCA 1 and 2 -- Cell Cycle Related Kinases -- ER -- Histone Deacetylases (HDAC) -- Methylation -- PR -- Retinoids -- Topoisomerase 1 -- Topoisomerase 2 -- VDR.
Record Nr. UNINA-9910483378603321
New York : , : Springer, , [2017]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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