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Advances in understanding genetic changes in cancer [[electronic resource] ] : impact on diagnosis and treatment decisions in the 1990s : a research briefing from the Division of Health Sciences Policy, Institute of Medicine
| Advances in understanding genetic changes in cancer [[electronic resource] ] : impact on diagnosis and treatment decisions in the 1990s : a research briefing from the Division of Health Sciences Policy, Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1992 |
| Descrizione fisica | 1 online resource (96 p.) |
| Soggetto topico |
Cancer - Genetic aspects
Cancer - Research - United States |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-20304-8
9786610203048 0-309-57260-6 0-585-08536-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910454865903321 |
| Washington, D.C., : National Academy Press, 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in understanding genetic changes in cancer [[electronic resource] ] : impact on diagnosis and treatment decisions in the 1990s : a research briefing from the Division of Health Sciences Policy, Institute of Medicine
| Advances in understanding genetic changes in cancer [[electronic resource] ] : impact on diagnosis and treatment decisions in the 1990s : a research briefing from the Division of Health Sciences Policy, Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1992 |
| Descrizione fisica | 1 online resource (96 p.) |
| Soggetto topico |
Cancer - Genetic aspects
Cancer - Research - United States |
| ISBN |
1-280-20304-8
9786610203048 0-309-57260-6 0-585-08536-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778880003321 |
| Washington, D.C., : National Academy Press, 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in understanding genetic changes in cancer : impact on diagnosis and treatment decisions in the 1990s : a research briefing from the Division of Health Sciences Policy, Institute of Medicine
| Advances in understanding genetic changes in cancer : impact on diagnosis and treatment decisions in the 1990s : a research briefing from the Division of Health Sciences Policy, Institute of Medicine |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1992 |
| Descrizione fisica | 1 online resource (96 p.) |
| Disciplina | 616.99 |
| Soggetto topico |
Cancer - Genetic aspects
Cancer - Research - United States |
| ISBN |
1-280-20304-8
9786610203048 0-309-57260-6 0-585-08536-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | ADVANCES IN UNDERSTANDING GENETIC CHANGES IN CANCER -- Copyright -- Statement of Purpose -- Contents -- ADVANCES IN UNDERSTANDING GENETIC CHANGES IN CANCER -- 1 Introduction -- OUTLINE OF MOLECULAR GENETICS -- BRIEF OVERVIEW OF CANCER GENETICS -- 2 Testing for Tumor-Specific Genetic Markers -- MICROSCOPIC DETECTION OF ALTERATIONS IN DNA STRUCTURE -- In Situ Hybridization -- Ploidy Analysis -- TECHNIQUES FOR DETECTING CHANGES IN DNA STRUCTURE AT THE SUBMICROSCOPIC LEVEL -- Southern Blot Hybridization -- Pulsed-Field Gel Electrophoresis -- Polymerase Chain Reaction -- TECHNIQUES FOR DETECTION OF POINT MUTATIONS IN DNA -- TECHNIQUES DIRECTED AT ANALYSIS OF RNA -- TECHNIQUES FOR ANALYZING CHANGES AT THE PROTEIN LEVEL -- Immunohistochemistry -- 3 Hematologic Cancer -- CHRONIC MYELOGENOUS LEUKEMIA -- CHRONIC LYMPHOCYTIC LEUKEMIA -- ACUTE LYMPHOCYTIC LEUKEMIA -- ACUTE MYELOGENOUS LEUKEMIA -- MYELODYSPLASTIC SYNDROMES -- LYMPHOMA -- 4 Solid Tumors -- CHROMOSOMAL ABERRATIONS OF DIAGNOSTIC IMPORTANCE -- CHROMOSOMAL ABERRATIONS OF PROGNOSTIC IMPORTANCE -- Neuroblastoma -- Breast Cancer -- Lung Cancer -- Other Solid Tumors -- GENETIC MARKERS OF PREDISPOSITION TO CANCER -- Retinoblastoma -- Mapping of Other Cancer Predisposition Loci -- Li-Fraumeni Syndrome -- Loss of Heterozygosity in Sporadic Solid Tumors -- GENETIC CHANGES AND TUMOR PROGRESSION -- Colorectal Neoplasms -- Glial Tumors -- CANCER-ASSOCIATED GENETIC CHANGES AND ENVIRONMENTAL MUTAGENS -- VIRAL MARKERS IN CANCER DIAGNOSIS -- 5 Summary and Specific Recommendations -- PRACTICAL ASPECTS OF GENETIC ANALYSIS: FROM PATIENT TO DIAGNOSTIC LABORATORY -- THE MOLECULAR DIAGNOSTIC LABORATORY -- IMPLICATIONS OF COMMERCIALIZATION -- FUTURE NEEDS -- 6 References. |
| Record Nr. | UNINA-9910825995603321 |
| Washington, D.C., : National Academy Press, 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomolecular therapeutics for human cancer / / edited by Antonio Giordano, Marcella Macaluso
| Biomolecular therapeutics for human cancer / / edited by Antonio Giordano, Marcella Macaluso |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Blackwell, c2011 |
| Descrizione fisica | 1 online resource (420 p.) |
| Disciplina | 616.99/4042 |
| Altri autori (Persone) |
GiordanoAntonio
MacalusoMarcella |
| Collana | Cancer epigenetics |
| Soggetto topico |
Cancer - Genetic aspects
Cancer - Treatment Epigenesis DNA - Methylation |
| ISBN |
1-283-11068-7
9786613110688 1-118-00573-2 1-118-00574-0 1-118-00572-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
(Publisher-supplied data) Section I: Epigenetics and Cell Cycle -- Epigenetic modulation of Cell Cycle: an overview? / by Micaela Montanari, Antonio Giordano, Marcella Cintorino and Marcella Macaluso -- Section II: Epigenetics and Cell Development, Senescence and Differentiation -- Epigenetic in skeletal muscle Development? / by Cristina Giacinti and Antonio Giordano -- Epigenetic control in cellular senescence? / by Heike Helmbold, Wolfgang Deppert, and Wolfgang Bohn -- Epigenetic modulation in cell development and differentiation? / by Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata Vocca and Francesca Pentimalli -- Section III: Epigenetics and Gene Transcription -- Epigenetic control of gene transcription? / by Christian Bronner, Mayada Achour, Thierry Chataigneau and Valerie B. Schini-Kerth -- Epigenetics, microRNAs and cancer: an update? / by Giuseppe Russo1, Andrew Puca, Francesco Masulli, Stefano Rovetta, Letizia Cito, Debora Muresu, Flavio Rizzolio and Antonio Giordano -- Section IV: Epigenetics and Cancer -- Epigenetics and Cancer? by Michael J. Powell, Vladimir M. Popov, Xiang Wang, Steven B. McMahon, Alexander Mazo, and Richard G. Pestell --
The MBD4/MED1 Protein in DNA Repair, DNA Demethylation, Disease and Cancer? / Serena Buontempo, Mara Sannai and Alfonso Bellacosa -- Epigenetics in pediatric cancers? by Roberta Ciarapica, Lavinia Raimondi, Federica Verginelli, Rossella Rota -- Epigenetic mechanisms in cancer formation and progression? by Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral, Michele Maio -- Section V: Epigenetics and Anticancer Drug Development and Therapy -- Recent advances in the field of stem cell research: towards the definition of the epigenetic and genetic codes of pluripotency? / by Gaetano Romano -- Potential of Heat Shock Protein Targeting for Human Therapy? / by Laszlo Otvos, Jr -- Advancements in Stem Cell Therapy & Research? /by Andrew Puca and Antonio Giordano. |
| Record Nr. | UNINA-9910140979703321 |
| Hoboken, N.J., : Wiley-Blackwell, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer . Primer of the molecular biology of cancer : principles & practice of oncology / / editors, Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg
| Cancer . Primer of the molecular biology of cancer : principles & practice of oncology / / editors, Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | Philadelphia : , : Wolters Kluwer, , [2021] |
| Descrizione fisica | 1 online resource (1011 pages) |
| Disciplina | 616.994 |
| Soggetto topico |
Cancer - Molecular aspects
Cancer - Genetic aspects Neoplasms - genetics |
| ISBN | 1-9751-4913-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910795673203321 |
| Philadelphia : , : Wolters Kluwer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer and noncoding RNAs . Volume 1 / / edited by Dr. Jayprokas Chakrabarti, M.Sc., Ph.D., Principal Investigator/Senior Professor, Indian Association for the Cultivation of Sciences (IACS), Kolkata, India, Dr. Sanga Mitra, Visiting Fellow, NIDDK, NIH, Bethesda, MD
| Cancer and noncoding RNAs . Volume 1 / / edited by Dr. Jayprokas Chakrabarti, M.Sc., Ph.D., Principal Investigator/Senior Professor, Indian Association for the Cultivation of Sciences (IACS), Kolkata, India, Dr. Sanga Mitra, Visiting Fellow, NIDDK, NIH, Bethesda, MD |
| Pubbl/distr/stampa | London, [England] : , : Academic Press, , 2018 |
| Descrizione fisica | 1 online resource (578 pages) |
| Disciplina | 572.88 |
| Collana | Translational Epigenetics Series |
| Soggetto topico |
Non-coding RNA
Cancer - Genetic aspects |
| ISBN |
0-12-813437-2
0-12-811022-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910583382503321 |
| London, [England] : , : Academic Press, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer and the environment [[electronic resource] ] : gene-environment interaction / / Samuel Wilson [et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine
| Cancer and the environment [[electronic resource] ] : gene-environment interaction / / Samuel Wilson [et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C. (2101 Constitution Ave., N.W. Washington, DC 20418), : National Academy Press, c2002 |
| Descrizione fisica | 1 online resource (160 p.) |
| Disciplina | 616.99/4071 |
| Altri autori (Persone) | WilsonSamuel H. <1939-2021.> |
| Soggetto topico |
Carcinogenesis
Cancer - Genetic aspects Cancer - Environmental aspects |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-18351-9
9786610183517 0-309-50506-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Foreword""; ""Preface""; ""Contents""; ""Summary""; ""1 Charge to Participants and Workshop Objectives""; ""2 Keynote Addresses""; ""3 The Links Between Environmental Factors, Genetics, and the Development of Cancer""; ""4 Gene�Environment Interaction in Special Populations""; ""5 Gene�Environment Interaction in Site-Specific Cancers""; ""6 Special Address: A Novel Approach to Cancer Treatment Based on Immune Stimulation and Other Environmental Approaches""; ""7 Cancer and the Environment: A View from the Hill""; ""8 Moving Forward""; ""Abstracts of Talks""
""References""""Appendix A Glossary""; ""Appendix B Workshop Agenda""; ""Appendix C Speakers and Panelists""; ""Appendix D Workshop Participants"" |
| Record Nr. | UNINA-9910455997203321 |
| Washington, D.C. (2101 Constitution Ave., N.W. Washington, DC 20418), : National Academy Press, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cancer and the environment [[electronic resource] ] : gene-environment interaction / / Samuel Wilson [et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine
| Cancer and the environment [[electronic resource] ] : gene-environment interaction / / Samuel Wilson [et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C. (2101 Constitution Ave., N.W. Washington, DC 20418), : National Academy Press, c2002 |
| Descrizione fisica | 1 online resource (160 p.) |
| Disciplina | 616.99/4071 |
| Altri autori (Persone) | WilsonSamuel H. <1939-2021.> |
| Soggetto topico |
Carcinogenesis
Cancer - Genetic aspects Cancer - Environmental aspects |
| ISBN |
0-309-16924-0
1-280-18351-9 9786610183517 0-309-50506-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Foreword""; ""Preface""; ""Contents""; ""Summary""; ""1 Charge to Participants and Workshop Objectives""; ""2 Keynote Addresses""; ""3 The Links Between Environmental Factors, Genetics, and the Development of Cancer""; ""4 Gene�Environment Interaction in Special Populations""; ""5 Gene�Environment Interaction in Site-Specific Cancers""; ""6 Special Address: A Novel Approach to Cancer Treatment Based on Immune Stimulation and Other Environmental Approaches""; ""7 Cancer and the Environment: A View from the Hill""; ""8 Moving Forward""; ""Abstracts of Talks""
""References""""Appendix A Glossary""; ""Appendix B Workshop Agenda""; ""Appendix C Speakers and Panelists""; ""Appendix D Workshop Participants"" |
| Record Nr. | UNINA-9910780135003321 |
| Washington, D.C. (2101 Constitution Ave., N.W. Washington, DC 20418), : National Academy Press, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cancer and the environment : gene-environment interaction / / Samuel Wilson [et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine
| Cancer and the environment : gene-environment interaction / / Samuel Wilson [et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C. (2101 Constitution Ave., N.W. Washington, DC 20418), : National Academy Press, c2002 |
| Descrizione fisica | 1 online resource (160 p.) |
| Disciplina | 616.99/4071 |
| Altri autori (Persone) | WilsonSamuel H. <1939-> |
| Soggetto topico |
Carcinogenesis
Cancer - Genetic aspects Cancer - Environmental aspects |
| ISBN |
0-309-16924-0
1-280-18351-9 9786610183517 0-309-50506-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Foreword""; ""Preface""; ""Contents""; ""Summary""; ""1 Charge to Participants and Workshop Objectives""; ""2 Keynote Addresses""; ""3 The Links Between Environmental Factors, Genetics, and the Development of Cancer""; ""4 Gene�Environment Interaction in Special Populations""; ""5 Gene�Environment Interaction in Site-Specific Cancers""; ""6 Special Address: A Novel Approach to Cancer Treatment Based on Immune Stimulation and Other Environmental Approaches""; ""7 Cancer and the Environment: A View from the Hill""; ""8 Moving Forward""; ""Abstracts of Talks""
""References""""Appendix A Glossary""; ""Appendix B Workshop Agenda""; ""Appendix C Speakers and Panelists""; ""Appendix D Workshop Participants"" |
| Record Nr. | UNINA-9910811549903321 |
| Washington, D.C. (2101 Constitution Ave., N.W. Washington, DC 20418), : National Academy Press, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cancer biology review [[electronic resource] ] : a case-based approach / / editor, Walter M. Stadler
| Cancer biology review [[electronic resource] ] : a case-based approach / / editor, Walter M. Stadler |
| Pubbl/distr/stampa | New York, : Demos Medical Publishing, LLC, 2014 |
| Descrizione fisica | 1 online resource (208 p.) |
| Disciplina | 362.19699/40072 |
| Altri autori (Persone) | StadlerWalter Michael |
| Soggetto topico |
Cancer - Genetic aspects
Cancer - Research |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61705-140-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title; Copyright; Contents; Contributors; Preface; 1. DNA Synthesis and Repair; A. Fundamentals of DNA Synthesis; Manish Sharma and Blase Polite; Overview; Clinical Translation: Mechanism of Action for Nucleotide Analog Agents and Antifolates; Clinical Translation: Mechanism of Action for Topoisomerase-Interacting Agents; Key Concepts; References; B. Fundamentals of DNA Damage and Repair; Philip Connell and Rita Nanda; Overview; Clinical Translation: Mechanism of Action for Radiotherapy; Clinical Translation: Mechanism of Action for Platinum Analogs
Clinical Translation: BRCA1/2: Cancer Predisposition and Interaction With PARP InhibitorsClinical Translation: Hereditary Nonpolyposis Colorectal Cancer Predisposition Syndromes; Key Concepts; References; C. DNA Mutations and Alterations: Applications to Cancer Therapy; Amy L. Kaufman and Peter H. O'Donnell; Overview; Clinical Translation: Irinotecan; Clinical Translation: 6-Mercaptopurine; Key Concepts; References; 2. RNA Transcription and Translation; A. Fundamentals of RNA Transcription and Translation; Overview; Clinical Translation: Transcriptional Profiling in Cancer; Key Concepts ReferencesBibliography; B. microRNAs; Overview; Clinical Translation: microRNAs Diagnostics; Key Concepts; References; Bibliography; 3. Chromosomal Dynamics and Stability; A. Fundamentals of Chromosomal Organization and Epigenetic Modification; Christopher J. Mariani, Erika L. Moen, Kelly R. Ostler, and Lucy A. Godley; Overview; Clinical Translation: Mechanism of Action for Histone Deacetylase Inhibitors; Clinical Translation: Mechanism of Action of Hypomethylating Agents; Key Concepts; References; B. Fundamentals of Chromosome Structure and Segregation Christopher J. Mariani, Trisha Macrae, Michael Daunov, and Lucy A. GodleyOverview; Clinical Translation: Cancer Associated Chromosomal Translocations as Diagnostic Markers; Clinical Translation: Mechanism of Tubule Inhibitors; Key Concepts; References; 4. Cell Surface Receptors and Signal Transduction; A. Fundamentals of Growth Factor Receptor Tyrosine Kinase Signaling; Overview; Clinical Translation: Mechanism of Action of EGFR/HER2 and MET Inhibitors; Key Concepts; References; B. Fundamentals of Signal Transduction; Overview Clinical Translation: Clinical Implications for RAF and RAS MutationsClinical Translation: Mechanism of Action for PI3K and AKT Pathway Inhibitors; Clinical Translation: Mechanism of Action of IL6/JAK/STAT Inhibitors; Key Concepts; References; 5. Nuclear Hormone Receptors; A. Overview of Nuclear Hormone Receptors in Malignancy; Russell Z. Szmulewitz; References; B. Androgen Receptor and Estrogen Receptor; Russell Z. Szmulewitz and James E. Ward; Overview; Clinical Translation: Mechanism of Estrogen Receptor (ER) Antagonism in Breast Cancer Clinical Translation: Modulation of the AR Axis in Prostate Cancer |
| Record Nr. | UNINA-9910463775103321 |
| New York, : Demos Medical Publishing, LLC, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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