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'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine [[electronic resource] /] / edited by Nosheen Masood, Saima Shakil Malik
'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine [[electronic resource] /] / edited by Nosheen Masood, Saima Shakil Malik
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XVIII, 499 p. 59 illus., 50 illus. in color.)
Disciplina 616.994042
Soggetto topico Cancer research
Oncology  
Human genetics
Bioinformatics
Nanotechnology
Genètica humana
Càncer
Oncologia
Bioinformàtica
Nanotecnologia
Cancer Research
Oncology
Human Genetics
Nanotechnology and Microengineering
Soggetto genere / forma Llibres electrònics
ISBN 981-15-1067-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Module 1_ Introduction -- Module 2_ Cancer Metastasis -- Module 3_ Role of Transcriptomics in cancer treatment strategies -- Module 4_Computational approaches -- Module 5_Biostatistics and clinical oncology -- Module 6_Pharmacogenomics in cancer -- Chapter 7_Case studies.
Record Nr. UNINA-9910409704903321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020
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Advanced Concepts in Human Immunology: Prospects for Disease Control / / edited by Pooja Jain, Lishomwa C. Ndhlovu
Advanced Concepts in Human Immunology: Prospects for Disease Control / / edited by Pooja Jain, Lishomwa C. Ndhlovu
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XVIII, 403 p. 16 illus., 5 illus. in color.)
Disciplina 616.079
Soggetto topico Immunology
Vaccines
Infectious diseases
Cancer research
Immunologia
Sistema immunitari
Malalties autoimmunitàries
Càncer
Al·lèrgia
Malalties neurodegeneratives
Malalties infeccioses
Vaccine
Infectious Diseases
Cancer Research
Soggetto genere / forma Llibres electrònics
ISBN 3-030-33946-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Human Chronic Viruses: Pathogenesis, host response, and treatment -- 2. Defining the Role of Immunoproteomics in Human Immunotherapy -- 3. Microbiome and Cellular Players in Type 1 Diabetes: from Pathogenesis to Protection -- 4. Immune Mechanisms, Pathology, and Management of Allergic Ocular Diseases -- 5. Dendritic Cell-regulated T Cell Immunity and Tolerance against Acute Myeloid Leukemia -- 6. Perspectives on the Role of T cell Negative Immune Checkpoint Receptors in Health and Disease -- 7. Neuroprotective Immunity for Neurodegenerative and Neuroinfectious Diseases -- 8. Polycystic Ovary Syndrome: An overview of a complex, heterogeneous genetic condition.
Record Nr. UNINA-9910416101503321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
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Advanced machine learning approaches in cancer prognosis : challenges and applications / / Janmenjoy Nayak [and four others] editors
Advanced machine learning approaches in cancer prognosis : challenges and applications / / Janmenjoy Nayak [and four others] editors
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (461 pages)
Disciplina 006.31
Collana Intelligent systems reference library ; Volume 204.
Soggetto topico Cancer - Prognosis - Technological innovations
Machine learning
Artificial intelligence - Medical applications
Càncer
Pronòstic mèdic
Innovacions tecnològiques
Intel·ligència artificial en medicina
Aprenentatge automàtic
Soggetto genere / forma Llibres electrònics
ISBN 3-030-71975-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910482988603321
Cham, Switzerland : , : Springer, , [2021]
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Antibodies for treating cancer : basics, development, and applications / / Melvyn Little
Antibodies for treating cancer : basics, development, and applications / / Melvyn Little
Autore Little Melvyn <1945->
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (XI, 151 p. 34 illus. in color.)
Disciplina 616.99406
Soggetto topico Antineoplastic antibiotics
Health
Immunoglobulines
Immunoteràpia
Càncer
Soggetto genere / forma Llibres electrònics
ISBN 3-030-72599-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1 Life-saving antibodies – history of immunization -- 2 Current approaches for immunising against cancer -- 3 Function and Structure of antibodies -- 4 Of mice and men - production of therapeutic antibodies -- 5 Novel modular antibodies -- 6 Antibodies as “Magic Bullets” -- 7 Mediation of tumor cell destruction -- 8 Engagement of immune killer cells -- 9 Approved antibodies for cancer therapy -- 10 Bringing therapeutic antibodies on the market -- 11 Future developments – outlook.
Record Nr. UNINA-9910482959303321
Little Melvyn <1945->  
Cham, Switzerland : , : Springer, , [2021]
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Assessment of cancer screening : a primer / / Pamela M. Marcus
Assessment of cancer screening : a primer / / Pamela M. Marcus
Autore Marcus Pamela M
Pubbl/distr/stampa Cham, : Springer Nature, 2022
Descrizione fisica 1 online resource (138 p.)
Soggetto topico Early Detection of Cancer
Càncer
Diagnòstic
Cribratge
Soggetto genere / forma Llibres electrònics
Soggetto non controllato Cancer Prevention
Cancer Statistics
Cancer Performance Measures
Cancer Population Measures
Cancer Screening Process
Open Access
ISBN 3-030-94577-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910558694403321
Marcus Pamela M  
Cham, : Springer Nature, 2022
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Atlas of extreme facial cancer : challenges and solutions / / Ian Burton, Michael F. Klaassen, editors
Atlas of extreme facial cancer : challenges and solutions / / Ian Burton, Michael F. Klaassen, editors
Pubbl/distr/stampa Cham, Switzerland : , : Springer International Publishing, , [2022]
Descrizione fisica 1 online resource (467 pages) : color illustrations
Disciplina 616.99492059
Soggetto topico Face - Cancer - Surgery
Face - Surgery
Càncer
Cirurgia
Soggetto genere / forma Atles (Científic)
Llibres electrònics
ISBN 3-030-88334-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910568257803321
Cham, Switzerland : , : Springer International Publishing, , [2022]
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Cancer biology : how science works / / Carsten Carlberg and Eunike Velleuer
Cancer biology : how science works / / Carsten Carlberg and Eunike Velleuer
Autore Carlberg Carsten
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (179 pages)
Disciplina 616.994071
Soggetto topico Carcinogenesis
Cancer - Etiology
Càncer
Etiologia
Soggetto genere / forma Llibres electrònics
ISBN 3-030-75699-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Acknowledgements -- Contents -- Abbreviations -- 1 Introduction to Cancer -- 1.1 The Global Burden of Cancer -- 1.2 Categorization and Diagnosis of Tumors -- 1.3 Crucial Transitions in Cancer -- 1.4 Causes of Cancer -- 1.5 Cancer Prevention -- Further Reading -- 2 Oncogenes and Signal Transduction -- 2.1 Cellular Transformation -- 2.2 Activating Oncogenes in Signal Transduction Pathways -- 2.3 Oncogenic Translocations and Amplifications -- 2.4 The Hallmarks of Cancer Concept -- Further Reading -- 3 Tumor Suppressor Genes and Cell Fate Control -- 3.1 p53 - A Master Example -- 3.2 Tumor Suppressors and Oncogenes in Cell Cycle Control -- 3.3 Tumor Suppressor Inhibition and Cancer Onset -- Further Reading -- 4 Multi-step Tumorigenesis and Genome Instability -- 4.1 Characteristics of Tumor Growth -- 4.2 Multi-step Tumorigenesis -- 4.3 Genome Instability -- 4.4 Cancer Driver Mutations and Genes -- Further Reading -- 5 Cancer Genomics -- 5.1 Human Genetic Variation and Cancer Susceptibility -- 5.2 The Cancer Genome -- 5.3 Cancer Genome Projects -- Further Reading -- 6 Cancer Epigenomics -- 6.1 Epigenetic Mechanisms of Cancer -- 6.2 DNA Methylation and Cancer -- 6.3 Chromatin Changes and Cancer -- 6.4 Epigenetic Reprogramming in Cancer -- Further Reading -- 7 Aging and Cancer -- 7.1 Central Role of Aging During Chronic Diseases -- 7.2 The Hallmarks of Aging -- 7.3 Epigenetics of Aging -- 7.4 Telomeres and Replicative Immortality -- Further Reading -- 8 Tumor Microenvironment -- 8.1 The Impact of the Wound Healing Program for Cancer -- 8.2 Cell Types of the Tumor Microenvironment -- 8.3 Inducing Angiogenesis -- 8.4 Tumor-Promoting Inflammation -- 8.5 Deregulating Cellular Energetics -- Further Reading -- 9 Metastasis and Cachexia -- 9.1 The Metastatic Cascade -- 9.2 Epithelial-Mesenchymal Transition -- 9.3 Metastatic Colonization.
9.4 Cachexia -- Further Reading -- 10 Cancer Immunity -- 10.1 Outline of Cancer Immunity -- 10.2 Recognition of Tumor Antigens -- 10.3 Monoclonal Antibodies in Cancer Immunotherapy -- 10.4 Immune Cell Therapies -- Further Reading -- 11 Architecture of Cancer Therapies -- 11.1 Classical Cancer Treatments -- 11.2 Targeted Therapies -- 11.3 Precision Oncology -- Further Reading -- Glossary.
Record Nr. UNINA-9910490024603321
Carlberg Carsten  
Cham, Switzerland : , : Springer, , [2021]
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Cancer biomarkers in diagnosis and therapeutics / / edited by Adeeb Shehzad
Cancer biomarkers in diagnosis and therapeutics / / edited by Adeeb Shehzad
Pubbl/distr/stampa Singapore : , : Springer, , [2022]
Descrizione fisica 1 online resource (372 pages)
Disciplina 616.994075
Soggetto topico Cancer - Diagnosis
Càncer
Marcadors bioquímics
Diagnòstic
Soggetto genere / forma Llibres electrònics
ISBN 981-16-5758-0
981-16-5759-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910743224703321
Singapore : , : Springer, , [2022]
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Cancer diagnostics and therapeutics : current trends, challenges, and future perspectives / / S. K. Basu, Chinmay Kumar Panda, Subrata Goswami, editors
Cancer diagnostics and therapeutics : current trends, challenges, and future perspectives / / S. K. Basu, Chinmay Kumar Panda, Subrata Goswami, editors
Pubbl/distr/stampa Singapore : , : Springer, , [2022]
Descrizione fisica 1 online resource (525 pages)
Disciplina 616.994075
Soggetto topico Cancer - Diagnosis
Cancer - Treatment
Càncer
Diagnòstic
Soggetto genere / forma Llibres electrònics
ISBN 981-16-4752-6
981-16-4751-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Acknowledgements -- Contents -- Editors and Contributors -- About the Editors -- Contributors -- Part I: Basic Background -- 1: Fighting with Cancer: A Common Man´s Dilemma -- 1.1 Cancer -- 1.2 Types and Terminologies -- 1.3 Some Statistics -- 1.4 Role of Various Physicians and Nursing Care and the Available Treatment Options -- 1.4.1 Surgery -- 1.4.2 Chemotherapy -- 1.4.2.1 Radiotherapy -- 1.4.3 Cancer Pain Management and Palliative Care -- 1.5 Coping with Cancer Diagnosis and Treatments -- 1.6 Rays of Hope -- 1.7 Winning and Fighting Cancer -- 1.8 Conclusion -- References -- 2: Cell Biology and Cell Behavior in Cancer -- 2.1 Introduction -- 2.1.1 Eukaryotic Cell Structure -- 2.1.1.1 Cell Membrane -- 2.1.1.2 Cytoplasm -- Organic Molecules -- Organelles -- Organelles with Double Membranes -- NucleusNucleus -- Nuclear MembraneNuclear Membrane -- NeoplasmNeoplasm -- NucleolusNucleolus -- ChromosomeChromosome -- MitochondrionMitochondrion -- ChloroplastsChloroplasts -- Organelles with Single Membrane -- PeroxisomePeroxisome -- Endoplasmic ReticulumEndoplasmic Reticulum -- Golgi ApparatusGolgi Apparatus -- LysosomeLysosome -- 2.1.2 Cell Cycle -- 2.1.2.1 Basic Structure of DNA and Its Function -- 2.1.2.2 Eukaryotic Chromosome -- 2.1.2.3 Replication and Repairing of DNA -- 2.1.2.4 DNA Recombination -- 2.1.2.5 DNA Transcription -- 2.1.2.6 Cell Division -- Mitosis -- Meiosis -- 2.1.2.7 Basics of Heredity -- 2.1.2.8 Intracellular Signaling -- 2.2 Introduction to Cancer Biology -- 2.2.1 Factors Playing Behind Cancer -- 2.2.2 Hallmarks of Cancer -- 2.2.3 Classification of Cancer -- 2.2.4 Cancer Detection and Diagnosis -- 2.3 Conclusion -- References -- 3: Tumor Biology: An Introduction -- 3.1 Introduction: Cancer Perspective from Fundamental Biology -- 3.2 The Nature of Cancer and Its Types.
3.3 Environmental Insults-Mutagens, Carcinogens, and Cancer-Causing Mutations -- 3.4 Infectious Agents, Inflammation, and Cancer -- 3.5 Cellular and Genetic Basis of Cancer -- 3.5.1 Comparison of Cancer Cell and Normal Cell -- 3.5.2 Genetic View of Cancer -- 3.5.3 Tumorigenesis -- 3.5.4 Oncogenes and Tumor Suppressor Genes -- 3.5.5 Genome-Wide Approach -- 3.6 Temporal Variation of Cancer Incidence Rate in Different Populations -- 3.7 Prevention and Early Detection -- 3.8 Conclusion -- References -- 4: Role of Angiogenesis in Tumors -- 4.1 Introduction -- 4.2 Mechanisms of Angiogenesis -- 4.2.1 Angiogenesis from Endothelial Precursor Cells (EPCs) -- 4.2.2 Angiogenic Switch -- 4.3 Angiogenesis in Physiologic Processes -- 4.4 Angiogenesis in the Pathogenesis of Cancer -- 4.5 Angiogenesis: A Network of Signaling Pathways -- 4.5.1 Endogenous Pro-angiogenic Factors -- 4.5.2 VEGF -- 4.6 Angiogenesis Ahead of VEGF/VEGFR Pathway -- 4.6.1 Platelet-Derived Growth Factor (PDGF)/PDGFR -- 4.6.2 Fibroblast Growth Factor (FGF)/FGFR -- 4.6.3 Angiopoietins (Ang)/Tie2 -- 4.6.4 Hepatocyte Growth Factor (HGF)/MET -- 4.7 Inhibitors of Angiogenesis -- 4.7.1 Angiostatin -- 4.7.2 Endostatin -- 4.7.3 Thrombospondins (TSPs) -- 4.8 Angiogenesis and Cancer -- 4.8.1 Anti-Angiogenic Treatment of Cancer -- 4.9 Combinatorial Targeting of Multiple Pro-angiogenic Pathways: An Alternative to Overcome Resistance -- 4.10 Current and Emerging Multi-Targeting Anti-Angiogenic Agents -- 4.11 Our Research Endeavors -- 4.12 Conclusions -- References -- 5: Biology, Chemistry, and Physics of Cancer Cell Motility and Metastasis -- 5.1 Introduction -- 5.2 Biological Background -- 5.2.1 Equilibrium in Cell Population -- 5.2.2 Oncogene and Tumor Suppressor Genes -- 5.2.3 Cellular Adhesion -- 5.2.4 Cell Signaling -- 5.3 Cancer Cell Motility and Metastasis: Biology and Chemistry.
5.3.1 Cancer Cell Motility -- 5.3.1.1 RhoGTPase Family -- 5.3.1.2 Single Cell Motility -- 5.3.1.3 Motility of Collective Cells -- 5.3.2 Metastasis -- 5.3.2.1 Proteolytic Enzymes -- 5.3.2.2 Adhesion Proteins -- 5.4 Physical and Mechanical Processes in Cell Motility and Metastasis -- 5.4.1 Physical Interaction in Cell Motility -- 5.4.2 Cellular Mechanics in Intravasation -- 5.4.3 Forces Acting on the Circulating Tumor Cells -- 5.4.4 Extravasation of Circulating Tumor Cells -- 5.4.4.1 Receptor-Ligand Interactions of Circulating Tumor Cells -- 5.4.4.2 Physics behind the Location of Metastatic Site -- 5.5 Conclusions -- Appendix -- Biological Notes -- References -- Part II: Diagnostics and Theory -- 6: MRI, CT, and PETSCAN: Engineer´s Perspective -- 6.1 Introduction -- 6.2 Tomographic Imaging in Medical Diagnosis: Historical Developments -- 6.3 Magnetic Resonance Imaging (MRI) -- 6.3.1 The Machine: A Gigantic Chamber -- 6.3.2 Magnetic Moment -- 6.3.3 Nuclear Magnetic Moment -- 6.3.4 Classical Precession -- 6.3.5 Total Magnetization -- 6.3.6 Radiofrequency Pulse: Related Magnetization -- 6.4 MR Signal Detection -- 6.4.1 MR Signal Intensity -- 6.4.2 Relaxation: Spin-Lattice (T1) and Spin-Spin (T2) -- 6.4.3 Magnetic Gradient Coils -- 6.4.4 K-Space and Image Formation -- 6.4.5 Pulse Sequence -- 6.5 Computed Tomography -- 6.5.1 Basics of X-ray -- 6.5.2 Diagnostic Application of Radiography -- 6.5.3 Limitations of Radiography -- 6.6 Basic Principle of Computed Tomography -- 6.6.1 Image Viewing System -- 6.7 Components of CT Scanner -- 6.7.1 X-Ray Detector and Data Acquisition System -- 6.8 Reconstruction of CT Image -- 6.9 Evolution of CT Scanning Technology -- 6.9.1 First-Generation CT (Translate-Rotate Mode) -- 6.9.2 Second-Generation CT (Multidetector Translate-Rotate Mode) -- 6.9.3 Third-Generation CT (Rotate-Rotate Mode).
6.9.4 Fourth-Generation CT (Fixed-Rotate) -- 6.9.5 Electron Beam CT (Fixed-Fixed) -- 6.9.6 Helical CT -- 6.10 Clinical Application of CT Scan Image -- 6.11 PET Scan -- 6.12 PET Scan: Basic Principle -- 6.12.1 PET Scan Utilities -- 6.12.2 Early Detection of Malignant Tumors/Cancers -- 6.13 Conclusion -- References -- 7: Diffusion, MRI, and Cancer Diagnosis: Physicist´s Outlook -- 7.1 Introduction -- 7.2 Diffusion -- 7.2.1 Phenomenological Notion and Fick´s Laws of Diffusion -- 7.2.2 Molecular Backgrounds of Diffusion and Random Walk Model -- 7.2.3 Self-Diffusion -- 7.2.3.1 Self-Diffusion and Einstein´s MSD Relation -- 7.2.4 Anisotropic Self-Diffusion -- 7.3 MRI -- 7.3.1 NMR in the Context of MRI -- 7.3.1.1 Relaxation Effects -- 7.3.1.2 The Bloch Equation and Time Evolution of Bulk Magnetization -- 7.3.1.3 An Outline of the Basic Pulsed-NMR Experiment -- 7.3.1.4 Signal-to-Noise Ratio (SNR) -- 7.3.1.5 FID Signal s(t) to NMR Spectrum S(Omega) and Fourier Transformation -- 7.3.1.6 Measurements of Relaxation Times -- 7.3.1.7 Inverse Recovery (IR) Method for Measuring T1 -- 7.3.1.8 Spin-Echo (SE) Method and Measurement of T2 -- 7.3.1.9 Effects of Diffusion on Spin-Echo Signal -- 7.3.2 NMR Imaging: MRI -- 7.3.2.1 MRI of Our Body Organs -- 7.3.2.2 The Gradient Pulses -- 7.3.2.3 The ``Receiver or Detector System´´ of an MRI Unit -- 7.3.2.4 Image Contrast -- 7.3.2.5 Basic Components of a Standard MRI System -- 7.3.3 Diffusion MRI -- 7.3.3.1 Diffusion-Weighted Imaging (DWI) -- 7.3.3.2 The Stejskal and Tanner´s Pulsed-Field Gradient Spin-Echo (PFG-SE) Sequence -- 7.3.3.3 Apparent Diffusion Coefficient Mapping (ADC Mapping): Quantitative Analysis with DWI -- 7.3.3.4 High-Speed Diffusion Imaging: Use of Echo-Planar Imaging (EPI) -- 7.3.3.5 Diffusion Tensor Imaging (DTI) -- 7.3.3.6 Indices of Anisotropic Diffusion -- 7.3.3.7 Application Potential of DTI.
7.4 Cancer -- 7.4.1 Interpretation of DWI and Its Assessment -- 7.4.2 Clinical DWI in the Body: Some Technical Issues -- 7.4.3 Applications of DWI-ADC Mapping of Target Organs -- 7.4.3.1 Detection of Tumors -- 7.4.3.2 Characterization of Tumors -- 7.4.4 Distinguishing Tumors from Non-Tumors -- 7.4.4.1 Monitoring Treatment Response -- 7.4.4.2 Predicting Treatment Response -- 7.5 Conclusions -- Appendix -- References -- 8: Oncology: Radiation Oncologist´s View -- 8.1 Introduction -- 8.1.1 Historical Perspectives -- 8.2 Mechanism of Action of Radiation and the Biological Basis of Radiation Therapy -- 8.2.1 DNA Damage -- 8.2.2 Biological Basis for Radiation Therapy -- 8.3 Principles of Radiotherapy -- 8.4 Types of Radiation -- 8.4.1 Ionising Radiation -- 8.4.2 Ionising Electromagnetic Radiation -- 8.4.3 X-Rays -- 8.4.4 Gamma (γ) Rays -- 8.4.5 Ionising Particulate Radiation -- 8.5 Units Used in Radiation Oncology -- 8.6 Basics of Radiation Protection -- 8.7 Techniques of Radiotherapy -- 8.7.1 Conventional Radiotherapy (2D Technique) -- 8.7.2 Three-Dimensional Conformal Radiation Therapy (3DCRT) -- 8.7.2.1 The Planning Process of 3DCRT -- 8.7.3 IMRT: Intensity-Modulated Radiation Therapy (IMRT) -- 8.7.3.1 Planning System of IMRT -- 8.7.4 Image-Guided Radiation Therapy (IGRT) -- 8.7.4.1 Rationale for Image-Guided Radiation Therapy -- 8.7.5 Stereotactic Radiosurgery and Radiotherapy (SRS and SRT) -- 8.7.6 Volumetric Modulated Arc Therapy (VMAT) -- 8.7.7 Surface-Guided Radiation Therapy (SGRT) -- 8.7.8 Brachytherapy -- 8.8 Fractionation in Radiotherapy -- 8.8.1 Types of Fractionation in Radiotherapy -- 8.9 Side Effects of Radiation -- 8.9.1 Early Effects (Acute Effects) -- 8.9.2 Late Effects -- 8.10 Conclusions -- References -- 9: Oncology: Biochemists´ Perspective -- 9.1 Introduction -- 9.2 Causes of Cancer -- 9.3 Development of Cancer -- 9.3.1 Initiation.
9.3.2 Promotion.
Record Nr. UNINA-9910743343503321
Singapore : , : Springer, , [2022]
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Cancer Drug Delivery Systems Based on the Tumor Microenvironment [[electronic resource] /] / edited by Yasuhiro Matsumura, David Tarin
Cancer Drug Delivery Systems Based on the Tumor Microenvironment [[electronic resource] /] / edited by Yasuhiro Matsumura, David Tarin
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Tokyo : , : Springer Japan : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (XI, 325 p. 118 illus., 73 illus. in color.)
Disciplina 615.19
Soggetto topico Pharmaceutical technology
Cancer research
Nanoscale science
Nanoscience
Nanostructures
Pharmaceutical Sciences/Technology
Cancer Research
Nanoscale Science and Technology
Càncer
Tecnologia farmacèutica
Soggetto genere / forma Llibres electrònics
ISBN 4-431-56880-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Part I Cancer pathophysiology -- 1. The Cancer Stroma and its relevance to tumor survival -- 2. Cancer and blood coagulation -- 3. Tumor Blood Vessels as targets for cancer therapy -- 4. Stromal barriers within the tumor microenvironment and obstacles to nanomedicine -- Part II Antibody drug conjugates (ADC) -- 1. Recent progress in linker technology for antibody-drug conjugates: Methods for connection and release -- 2. Preclinical studies of ADC therapy for solid tumors -- 3. ADCs on the market and in clinical development -- Part III Hybrid techniques of active and passive targeting -- 1. Micelles conjugated with a pilot molecule -- 2. Liposomes conjugated with a pilot molecule -- 3. Multifunctional Envelope-type Nano Devices (MEND) for cancer therapy -- Part IV Cancer stromal targeting (CAST) therapy and diagnosis -- 1. Principle of CAST -- 2. CAST therapy -- 3. CAST diagnosis -- Part V The Current Status of Cancer Drug Delivery Systems and Future Directions -- Index.
Record Nr. UNINA-9910373901303321
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2019
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