Oral contraceptives & breast cancer [[electronic resource] /] / Committee on the Relationship Between Oral Contraceptives and Breast Cancer, Institute of Medicine, Division of Health Promotion and Disease Prevention |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1991 |
Descrizione fisica | 1 online resource (195 p.) |
Disciplina | 616.99/449071 |
Soggetto topico |
Breast - Cancer - Epidemiology
Oral contraceptives - Side effects |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-20360-9
9786610203604 0-309-59763-3 0-585-14901-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910454871503321 |
Washington, D.C., : National Academy Press, 1991 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oral contraceptives & breast cancer [[electronic resource] /] / Committee on the Relationship Between Oral Contraceptives and Breast Cancer, Institute of Medicine, Division of Health Promotion and Disease Prevention |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1991 |
Descrizione fisica | 1 online resource (195 p.) |
Disciplina | 616.99/449071 |
Soggetto topico |
Breast - Cancer - Epidemiology
Oral contraceptives - Side effects |
ISBN |
1-280-20360-9
9786610203604 0-309-59763-3 0-585-14901-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910778876003321 |
Washington, D.C., : National Academy Press, 1991 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oral contraceptives & breast cancer / / Committee on the Relationship Between Oral Contraceptives and Breast Cancer, Institute of Medicine, Division of Health Promotion and Disease Prevention |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1991 |
Descrizione fisica | 1 online resource (195 p.) |
Disciplina | 616.99/449071 |
Soggetto topico |
Breast - Cancer - Epidemiology
Oral contraceptives - Side effects |
ISBN |
1-280-20360-9
9786610203604 0-309-59763-3 0-585-14901-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Oral Contraceptives & -- Breast Cancer -- Copyright -- Preface -- Contents -- Executive Summary -- MAINTAINING SURVEILLANCE -- DEVELOPING A BROADER ARRAY OF CONTRACEPTIVES -- ASSESSING KNOWLEDGE FOR APPLICATION IN CLINICAL PRACTICE -- FILLING GAPS IN BIOLOGICAL AND EPIDEMIOLOGICAL KNOWLEDGE -- 1 Introduction and Overview -- BIOLOGICAL PLAUSIBILITY OF A LINK BETWEEN ORAL CONTRACEPTIVES AND BREAST CANCER -- WHAT IS-AND IS NOT-KNOWN -- SEEKING ANSWERS -- 2 Epidemiology: Information Needs and Data Gaps -- EPIDEMIOLOGICAL RESEARCH -- Case-Control Method -- Cohort Studies -- Comparison Groups -- Ecological Studies -- Special Studies -- Women Exposed to Hormones Other than Oral Contraceptives -- Women Genetically Susceptible to Breast Cancer -- Estrogen Metabolism -- Progestins -- Changing Oral Contraceptive Formulations -- SUMMARY AND CONCLUSIONS -- 3 Biology: Information Needs and Data Gaps -- SIGNAL COMPLEXITY IN BREAST REGULATION -- RESEARCH ISSUES -- Relationships Among Cell Types -- Receptors -- Timing -- Effects of Pregnancy and Lactation -- Pathological Breast Tissue -- Oncogenes -- Molecular Changes Associated with Human Breast Cancer -- Activated ras Mutations -- Overexpression of Tyrosine Kinases -- Amplification of int-2 and myc -- Deletions of Genes -- RESEARCH MODELS -- Breast Cancer Cell Lines -- Short-term Culture of Normal Mammary Epithelium -- Organ Culture -- Nude Mouse Model -- SUMMARY AND CONCLUSIONS -- 4 Information for Users of the Pill and Health Care Providers -- BENEFITS AND RISKS OF ORAL CONTRACEPTIVES -- Benefits -- Risks -- CURRENT CONTROVERSY -- PRESCRIBING PROBLEMS -- 5 Policy Issues and Recommendations -- MAINTAINING SURVEILLANCE -- Cooperative Research -- Surveillance Requirements of the Food and Drug Administration -- DEVELOPING A BROADER ARRAY OF CONTRACEPTIVES.
ASSESSING KNOWLEDGE FOR APPLICATION IN CLINICAL PRACTICE -- FILLING GAPS IN BIOLOGICAL AND EPIDEMIOLOGICAL KNOWLEDGE -- References -- Appendixes -- A Oral Contraceptives and Breast Cancer: A Review of the Epidemiological Evidence with an Emphasis ... -- Changing Profile Of Oral Contraceptive Use -- Biological Plausibility -- Epidemiological Studies Of Breast Cancer and Oral Contraceptives -- Ever" Use of Oral Contraceptives -- Duration of Oral Contraceptive Use -- Oral Contraceptive Use Before First Full-term Pregnancy or Before Age 25 -- Duration Since First Use of Oral Contraceptives (Latency) -- Use of Oral Contraceptives in High-Risk Subgroups -- Steroidal Potency of Various Formulations -- Issues to Consider in Reviewing the Epidemiological Evidence -- Discussion -- The Future -- References -- B Oral Contraceptives and Breast Cancer: Review of the Epidemiological Literature -- Methods -- Results -- Risk of Oral Contraceptive Users of All Ages in Developed Countries -- Risk in Oral Contraceptive Users in Developing Countries -- Risk in Oral Contraceptive Users With and Without Various Risk Factors for Breast Cancer -- Risk in Relation to Early Use of Oral Contraceptives -- Screening Bias -- Risk in Relation to Use of Oral Contraceptives Near the Age of Menopause -- Individual Formulations and Constituents of Oral Contraceptives -- Conclusions, Interpretations, and Recommendations for Further Research -- Acknowledgments -- References -- C The Evolving Formulations of Oral Contraceptives -- Implications for Research -- References -- D Animal Models of Sex Steroid Hormones and Mammary Cancer: Lessons for Understanding Studies in Humans -- Direct Tests of Carcinogenicity -- Mice and Rats -- Beagle Dogs -- Pharmacokinetics of Various Steroids in Mice, Rats, and Beagles. Studies of Mechanisms for Mammary Carcinogenicity of Sex Steroid Hormones in Mice, Rats, and Dogs -- Conclusions -- Interesting Questions Raised by Animal Studies -- References -- E Risks and Benefits of Oral Contraceptives: Will Breast Cancer Tip the Balance? -- Established Benefits and Risks -- Balance of Benefits and Risks -- Oral Contraceptives and Breast Cancer -- An Effect in Young Women -- Conclusions -- References -- F List of Background Documents -- Index. |
Altri titoli varianti | Oral contraceptives and breast cancer |
Record Nr. | UNINA-9910817058303321 |
Washington, D.C., : National Academy Press, 1991 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Women at high genetic risk of breast cancer [[electronic resource] ] : a breast imaging study / / Clinical Genetics Branch, Division of Cancer, Epidemiology, and Genetics |
Pubbl/distr/stampa | [Bethesda, Md.] : , : U.S. Dept. of Health and Human Services, National Institutes of Health, National Cancer Institute, , [2003] |
Descrizione fisica | 1 online resource (2 unnumbered pages) : portraits |
Collana | NIH publication |
Soggetto topico |
Breast - Cancer - Research
Breast - Cancer - Epidemiology |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Women at high genetic risk of breast cancer |
Record Nr. | UNINA-9910699327403321 |
[Bethesda, Md.] : , : U.S. Dept. of Health and Human Services, National Institutes of Health, National Cancer Institute, , [2003] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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