Addiction and the brain : knowledge, beliefs and ethical considerations from a social perspective / / Matilda Hellman |
Autore | Hellman Matilda |
Pubbl/distr/stampa | Cham, Switzerland : , : Palgrave Macmillan, , [2022] |
Descrizione fisica | 1 online resource (221 pages) : illustrations |
Disciplina | 616.86 |
Soggetto topico |
Substance abuse
Brain - Effect of drugs on |
ISBN | 981-19-0946-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910564695503321 |
Hellman Matilda | ||
Cham, Switzerland : , : Palgrave Macmillan, , [2022] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Advances in non-invasive drug delivery to the brain / / editor, Richard Egleton |
Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2015 |
Descrizione fisica | 1 online resource (156 pages) : color illustrations |
Disciplina | 362.29 |
Soggetto topico |
Brain - Effect of drugs on
Neuropharmacology Drugs - Physiological transport Blood-brain barrier |
Soggetto genere / forma | Electronic books. |
ISBN |
1-909453-97-8
1-909453-93-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910467801803321 |
London, England : , : Future Science Ltd, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Advances in non-invasive drug delivery to the brain / / editor, Richard Egleton |
Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2015 |
Descrizione fisica | 1 online resource (156 pages) : color illustrations |
Disciplina | 362.29 |
Soggetto topico |
Brain - Effect of drugs on
Neuropharmacology Drugs - Physiological transport Blood-brain barrier |
ISBN |
1-909453-97-8
1-909453-93-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910794873603321 |
London, England : , : Future Science Ltd, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Advances in non-invasive drug delivery to the brain / / editor, Richard Egleton |
Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2015 |
Descrizione fisica | 1 online resource (156 pages) : color illustrations |
Disciplina | 362.29 |
Soggetto topico |
Brain - Effect of drugs on
Neuropharmacology Drugs - Physiological transport Blood-brain barrier |
ISBN |
1-909453-97-8
1-909453-93-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910814283703321 |
London, England : , : Future Science Ltd, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Blood-brain barrier in drug discovery : optimizing brain exposure of CNS drugs and minimizing brain side effects for peripheral drugs / / edited by Li Di, Edward H. Kerns |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons Inc., , [2015] |
Descrizione fisica | 1 online resource (607 p.) |
Disciplina | 615.7/8 |
Soggetto topico |
Brain - Effect of drugs on
Blood-brain barrier |
ISBN |
1-118-78852-4
1-118-78854-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Machine generated contents note: Summary List of Chapters1. Overview/Introduction / Li Di (Pfizer Inc.), Edward H. Kerns (Pharmacokinetics of Brain Exposure)2. Pharmacokinetics of CNS penetration / Andreas Reichel (Bayer)3. Free Drug Hyposthesis for CNS Drug Candidates / Xingrong Liu (Genentech)4. Species Differences and impact of desease state on BBB / Jean-Marie Nicolas (UCB Pharma S.A.)Mechanisms of Drugs Across the Blood-Brain Barrier5. Passive diffusion permeability of the BBB - examples and SAR / Phil Jeffrey (GSK)6. Efflux transport at the BBB - examples and SAR / Jerome Hochman (Merck)7. Uptake transport at the BBB - examples and SAR / Zack Cheng (AstraZeneca)8. Uptake of proteins and antibodies at the BBB / William Pardridge (UCLA)Predicting and Measuring Brain Exposure of Drugs9. In silico tools for assessing brain exposure / Hongming Chen (AstraZeneca)10. In vitro assays for assessing BBB permeability - vascular cells, artificial membranes, brain slice, cell uptake / Winfried Neuhaus (University of Vienna)11. Human-based in vitro endothelial cell models / Eric Shusta (University of Wisconsin)12. In vitro assays for assessing brain binding / Li Di (Pfizer)13. In vivo studies of brain exposure / Edward H. Kerns14. PBPK models for BBB / Elizabeth de Lange (Leiden University)15. PK/PD modeling of CNS drug candidates / Johan Gabrielsson (Swedish University)16. Microdialysis to assess free drug concentration in brain / William Kielbasa (Lilly)17. Imaging technique for CNS drug discovery / Lei Zhang (Pfizer Inc.)Modulating Brain Penetration of Leads During Drug Discovery18. Designing CNS drugs for optimal brain exposure / Zoran Rankovic (Lilly)19. Case studies of CNS drug optimization - medicinal chemistry and CNS biology perspectives / Kevin J. Hodgetts (Harvard NeuroDiscovery Center)20. Designing peripheral drugs for minimal brain exposue / Peter Bungay (Pfizer)21. Case studies of non-CNS drugs to minimize brain penetration - Nonsudative antihistamines / Andrew Crowe (Curtin University)Case Studies in CNS Drug Discovery22. Case study 1 on discovery of a successful CNS drug - Fycompa (AMPA Receptor Antagonist) / Andrew Satlin and Antonio Laurenza (Eisai)23. Case study 2 on discovery of a successful CNS drug - Vortioxetine (Serotonin Modulator and Stimulator) / Benny Bang-Andersen (Lundbeck)Drug Delivery Techniques to CNS24. Brain delivery using nanotechnology / Xinguo Jiang (Fudan University)25. Intranasal delivery to CNS / Lisbeth Illum (University of Nottingham)Future Prospective in Blood Brain Barrier Advancement26. Conclusion Remarks / Joan Abbott (King's College). |
Record Nr. | UNINA-9910132304003321 |
Hoboken, New Jersey : , : John Wiley & Sons Inc., , [2015] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Blood-brain barrier in drug discovery : optimizing brain exposure of CNS drugs and minimizing brain side effects for peripheral drugs / / edited by Li Di, Edward H. Kerns |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons Inc., , [2015] |
Descrizione fisica | 1 online resource (607 p.) |
Disciplina | 615.7/8 |
Soggetto topico |
Brain - Effect of drugs on
Blood-brain barrier |
ISBN |
1-118-78852-4
1-118-78854-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Machine generated contents note: Summary List of Chapters1. Overview/Introduction / Li Di (Pfizer Inc.), Edward H. Kerns (Pharmacokinetics of Brain Exposure)2. Pharmacokinetics of CNS penetration / Andreas Reichel (Bayer)3. Free Drug Hyposthesis for CNS Drug Candidates / Xingrong Liu (Genentech)4. Species Differences and impact of desease state on BBB / Jean-Marie Nicolas (UCB Pharma S.A.)Mechanisms of Drugs Across the Blood-Brain Barrier5. Passive diffusion permeability of the BBB - examples and SAR / Phil Jeffrey (GSK)6. Efflux transport at the BBB - examples and SAR / Jerome Hochman (Merck)7. Uptake transport at the BBB - examples and SAR / Zack Cheng (AstraZeneca)8. Uptake of proteins and antibodies at the BBB / William Pardridge (UCLA)Predicting and Measuring Brain Exposure of Drugs9. In silico tools for assessing brain exposure / Hongming Chen (AstraZeneca)10. In vitro assays for assessing BBB permeability - vascular cells, artificial membranes, brain slice, cell uptake / Winfried Neuhaus (University of Vienna)11. Human-based in vitro endothelial cell models / Eric Shusta (University of Wisconsin)12. In vitro assays for assessing brain binding / Li Di (Pfizer)13. In vivo studies of brain exposure / Edward H. Kerns14. PBPK models for BBB / Elizabeth de Lange (Leiden University)15. PK/PD modeling of CNS drug candidates / Johan Gabrielsson (Swedish University)16. Microdialysis to assess free drug concentration in brain / William Kielbasa (Lilly)17. Imaging technique for CNS drug discovery / Lei Zhang (Pfizer Inc.)Modulating Brain Penetration of Leads During Drug Discovery18. Designing CNS drugs for optimal brain exposure / Zoran Rankovic (Lilly)19. Case studies of CNS drug optimization - medicinal chemistry and CNS biology perspectives / Kevin J. Hodgetts (Harvard NeuroDiscovery Center)20. Designing peripheral drugs for minimal brain exposue / Peter Bungay (Pfizer)21. Case studies of non-CNS drugs to minimize brain penetration - Nonsudative antihistamines / Andrew Crowe (Curtin University)Case Studies in CNS Drug Discovery22. Case study 1 on discovery of a successful CNS drug - Fycompa (AMPA Receptor Antagonist) / Andrew Satlin and Antonio Laurenza (Eisai)23. Case study 2 on discovery of a successful CNS drug - Vortioxetine (Serotonin Modulator and Stimulator) / Benny Bang-Andersen (Lundbeck)Drug Delivery Techniques to CNS24. Brain delivery using nanotechnology / Xinguo Jiang (Fudan University)25. Intranasal delivery to CNS / Lisbeth Illum (University of Nottingham)Future Prospective in Blood Brain Barrier Advancement26. Conclusion Remarks / Joan Abbott (King's College). |
Record Nr. | UNINA-9910829110403321 |
Hoboken, New Jersey : , : John Wiley & Sons Inc., , [2015] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The brain's response to anabolic steroids [[electronic resource]] |
Edizione | [Rev. 2009.] |
Pubbl/distr/stampa | Rockville, Md : , : National Institute on Drug Abuse, National Institutes of Health, , 2009 |
Descrizione fisica | 1 online resource (2 unnumbered pages) : color illustrations |
Collana |
Mind over matter
NIH publication |
Soggetto topico |
Steroid abuse
Brain - Effect of drugs on |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910699060703321 |
Rockville, Md : , : National Institute on Drug Abuse, National Institutes of Health, , 2009 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The brain's response to inhalants |
Pubbl/distr/stampa | Rockville, MD : , : National Institute on Drug Abuse, National Institutes of Health, , 2006 |
Descrizione fisica | 1 online resource (2 unnumbered pages) : color illustrations |
Collana |
Mind over matter
NIH publication |
Soggetto topico |
Inhalant abuse
Brain - Effect of drugs on |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910699062103321 |
Rockville, MD : , : National Institute on Drug Abuse, National Institutes of Health, , 2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The brain's response to methamphetamine |
Pubbl/distr/stampa | Rockville, Md : , : National Institute on Drug Abuse, National Institutes of Health, , 2006 |
Descrizione fisica | 1 online resource (2 unnumbered pages) : color illustrations |
Collana |
Mind over matter
NIH publication |
Soggetto topico |
Methamphetamine abuse
Brain - Effect of drugs on |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910699061903321 |
Rockville, Md : , : National Institute on Drug Abuse, National Institutes of Health, , 2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The brain's response to nicotine |
Pubbl/distr/stampa | Rockville, Md. : , : National Institute on Drug Abuse, National Institutes of Health, U.S. Dept. of Health and Human Services, , 1998 |
Descrizione fisica | 1 online resource (2 unnumbered pages) : color illustrations |
Collana |
NIH publication
Mind over matter |
Soggetto topico |
Nicotine addiction
Brain - Effect of drugs on |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Mind over matter |
Record Nr. | UNINA-9910699061103321 |
Rockville, Md. : , : National Institute on Drug Abuse, National Institutes of Health, U.S. Dept. of Health and Human Services, , 1998 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|