An Act to Amend Title 35, United States Code, with Respect to Patents on Biotechnological Processes |
Pubbl/distr/stampa | [Washington, D.C.] : , : [U.S. Government Printing Office], , [1995] |
Descrizione fisica | 1online resource (2 unnumbered pages) |
Soggetto topico |
Patent laws and legislation - United States
Biotechnological process control |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910708281003321 |
[Washington, D.C.] : , : [U.S. Government Printing Office], , [1995] | ||
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Lo trovi qui: Univ. Federico II | ||
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Bioprocess control [[electronic resource] /] / edited by Denis Dochain |
Pubbl/distr/stampa | London, : ISTE |
Descrizione fisica | 1 online resource (244 p.) |
Disciplina | 660.6 |
Altri autori (Persone) | DochainD <1956-> (Denis) |
Collana | ISTE |
Soggetto topico |
Biotechnological process control
Biotechnological process monitoring |
ISBN |
1-282-16502-X
9786612165023 0-470-61112-X 0-470-39371-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Bioprocess Control; Contents; Chapter 1. What are the Challenges for the Control of Bioprocesses?; 1.1. Introduction; 1.2. Specific problems of bioprocess control; 1.3. A schematic view of monitoring and control of a bioprocess; 1.4. Modeling and identification of bioprocesses: some key ideas; 1.5. Software sensors: tools for bioprocess monitoring; 1.6. Bioprocess control: basic concepts and advanced control; 1.7. Bioprocess monitoring: the central issue; 1.8. Conclusions; 1.9. Bibliography; Chapter 2. Dynamic Models of Biochemical Processes: Properties of Models; 2.1. Introduction
2.2. Description of biochemical processes2.2.1. Micro-organisms and their use; 2.2.2. Types of bioreactors; 2.2.3. Three operating modes; 2.3. Mass balance modeling; 2.3.1. Introduction; 2.3.2. Reaction scheme; 2.3.3. Choice of reactions and variables; 2.3.4. Example 1; 2.4. Mass balance models; 2.4.1. Introduction; 2.4.2. Example 2; 2.4.3. Example 3; 2.4.4. Matrix representation; 2.4.4.1. Example 2 (continuation); 2.4.4.2. Example 1 (continuation); 2.4.5. Gaseous ow; 2.4.6. Electroneutrality and affinity constants; 2.4.7. Example 1 (continuation); 2.4.8. Conclusion; 2.5. Kinetics 2.5.1. Introduction2.5.2. Mathematical constraints; 2.5.2.1. Positivity of variables; 2.5.2.2. Variables necessary for the reaction; 2.5.2.3. Example 1 (continuation); 2.5.2.4. Phenomenological knowledge; 2.5.3. Specific growth rate; 2.5.4. Representation of kinetics by means of a neural network; 2.6. Validation of the model; 2.6.1. Introduction; 2.6.2. Validation of the reaction scheme; 2.6.2.1. Mathematical principle; 2.6.2.2. Example 4; 2.6.3. Qualitative validation of model; 2.6.4. Global validation of the model; 2.7. Properties of the models 2.7.1. Boundedness and positivity of variables2.7.2. Equilibrium points and local behavior; 2.7.2.1. Introduction; 2.8. Conclusion; 2.9. Bibliography; Chapter 3. Identification of Bioprocess Models; 3.1. Introduction; 3.2. Structural identifiability; 3.2.1. Development in Taylor series; 3.2.2. Generating series; 3.2.3. Examples for the application of the methods of development in series; 3.2.4. Some observations on the methods for testing structural identifiability; 3.3. Practical identifiability; 3.3.1. Theoretical framework; 3.3.2. Confidence interval of the estimated parameters 3.3.3. Sensitivity functions3.4. Optimum experiment design for parameter estimation (OED/PE); 3.4.1. Introduction; 3.4.2. Theoretical basis for the OED/PE; 3.4.3. Examples; 3.5. Estimation algorithms; 3.5.1. Choice of two datasets; 3.5.2. Elements of parameter estimation: least squares estimation in the linear case; 3.5.3. Overview of the parameter estimation algorithms; 3.6. A case study: identification of parameters for a process modeled for anaerobic digestion; 3.6.1. The model; 3.6.2. Experiment design; 3.6.3. Choice of data for calibration and validation; 3.6.4. Parameter identification 3.6.5. Analysis of the results |
Record Nr. | UNINA-9910139468103321 |
London, : ISTE | ||
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Lo trovi qui: Univ. Federico II | ||
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Bioprocesses for value-added products from renewable resources [[electronic resource] ] : new technologies and applications / / edited by Shang-Tian Yang |
Pubbl/distr/stampa | Amsterdam ; ; Boston, MA, : Elsevier, 2006 |
Descrizione fisica | 1 online resource (685 p.) |
Disciplina | 660.6/3 |
Altri autori (Persone) | YangShang-Tian |
Soggetto topico |
Biochemical engineering
Biotechnological process control Renewable natural resources |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-72921-X
9786610729210 0-08-046671-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Preface; 2. Applications of genomic and proteomic analyses; 3. Bioprocess analysis and optimization guided by genomic and proteomic analyses: The example of microbial production of 1,3-propanediol; 4. Concluding remarks and outlook; References; 2. Directed evolution tools for diversity generation; 3. Applications of directed evolution tools; 4. Alternatives to directed evolution; 5. Conclusion; Acknowledgements; References; 2. Applications and some examples; 3. Metabolic engineering strategies and limitations; 4. Metabolic engineering methodologies and tools
5. Challenges and new approaches for metabolic engineering 6. Summary; References; 2. Amylase and cellulase classification and mechanisms; 3. Conclusions; Acknowledgment; References; 2. Various types of bioreactors; 3. Effects of process parameters on biological performances; 4. Industrial applications of bioreactors; 5. Trends in bioreactor engineering; Acknowledgments; References; 3. Microfiltration and ultrafiltration processes; 4. Membrane fouling; 5. Applications in biotechnology industries; 5.3. Other applications; 6. Outlook; References; 2. Bacteria; 3. Yeast 4. Fermentation products from bacteria and yeasts 5. Fermentation processes; 6. Conclusion and outlook; References; 2. Fungal cells as biofactories; 3. Hyphal growth and protein secretion; 4. Fungal growth in submerged culture; 5. Effects of cultivation conditions; 6. Effects of morphology on production and secretion; 7. Immobilized fungal cells; 8. Future of filamentous fungal cells as biofactories; References; 2. Production of macromolecules; 3. Production of small molecules; Acknowledgements; References; 2. Modes of micro-algal cultivation; 3. Thraustochytrids 4. High-value products from thraustochytrids 5. Other applications of thraustochytrids; 6. Utilization of renewable resources; 7. Safety issues; 8. Conclusions; 7 References; 2. Enzymatic treatment of biomass components; 3. Further processing of simple renewable molecules for value-added products; 4. New trends in enzymatic bioprocessing; 5. Summary; References; 3. Chiral molecules from hydrolase; 4. Chiral molecules from enzymes requiring cofactors; 5. Improving enantioselectivity by reaction engineering; 6. Improving chiral synthesis by directed evolution and metabolic engineering 7. Conclusions References; 2. Immobilization techniques; 3. Effects of cell immobilization; 4. Immobilized cell bioreactors; 5. Applications of immobilized cell technology; 6. Conclusion; References; 3. New process development; 4. Water-in-oil cultivation technology; 5. PH-sensitive surfactants for water-in-oil cultivation; 6. Conclusions; References; 2. Carboxylic acid fermentation; 3. Integrated fermentation-separation processes; 4. Summary and outlook; References; 3. Fungal metabolites; 4. Pathway manipulation; 5. Conclusions; References; 3. Advantages and unsolved problems; 4. SSF reactors 5. Conclusions |
Altri titoli varianti | Bioprocesses for value added products from renewable resources |
Record Nr. | UNINA-9910457247803321 |
Amsterdam ; ; Boston, MA, : Elsevier, 2006 | ||
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Lo trovi qui: Univ. Federico II | ||
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Bioprocesses for value-added products from renewable resources [[electronic resource] ] : new technologies and applications / / edited by Shang-Tian Yang |
Pubbl/distr/stampa | Amsterdam ; ; Boston, MA, : Elsevier, 2006 |
Descrizione fisica | 1 online resource (685 p.) |
Disciplina | 660.6/3 |
Altri autori (Persone) | YangShang-Tian |
Soggetto topico |
Biochemical engineering
Biotechnological process control Renewable natural resources |
ISBN |
1-280-72921-X
9786610729210 0-08-046671-0 |
Classificazione | 58.31 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Preface; 2. Applications of genomic and proteomic analyses; 3. Bioprocess analysis and optimization guided by genomic and proteomic analyses: The example of microbial production of 1,3-propanediol; 4. Concluding remarks and outlook; References; 2. Directed evolution tools for diversity generation; 3. Applications of directed evolution tools; 4. Alternatives to directed evolution; 5. Conclusion; Acknowledgements; References; 2. Applications and some examples; 3. Metabolic engineering strategies and limitations; 4. Metabolic engineering methodologies and tools
5. Challenges and new approaches for metabolic engineering 6. Summary; References; 2. Amylase and cellulase classification and mechanisms; 3. Conclusions; Acknowledgment; References; 2. Various types of bioreactors; 3. Effects of process parameters on biological performances; 4. Industrial applications of bioreactors; 5. Trends in bioreactor engineering; Acknowledgments; References; 3. Microfiltration and ultrafiltration processes; 4. Membrane fouling; 5. Applications in biotechnology industries; 5.3. Other applications; 6. Outlook; References; 2. Bacteria; 3. Yeast 4. Fermentation products from bacteria and yeasts 5. Fermentation processes; 6. Conclusion and outlook; References; 2. Fungal cells as biofactories; 3. Hyphal growth and protein secretion; 4. Fungal growth in submerged culture; 5. Effects of cultivation conditions; 6. Effects of morphology on production and secretion; 7. Immobilized fungal cells; 8. Future of filamentous fungal cells as biofactories; References; 2. Production of macromolecules; 3. Production of small molecules; Acknowledgements; References; 2. Modes of micro-algal cultivation; 3. Thraustochytrids 4. High-value products from thraustochytrids 5. Other applications of thraustochytrids; 6. Utilization of renewable resources; 7. Safety issues; 8. Conclusions; 7 References; 2. Enzymatic treatment of biomass components; 3. Further processing of simple renewable molecules for value-added products; 4. New trends in enzymatic bioprocessing; 5. Summary; References; 3. Chiral molecules from hydrolase; 4. Chiral molecules from enzymes requiring cofactors; 5. Improving enantioselectivity by reaction engineering; 6. Improving chiral synthesis by directed evolution and metabolic engineering 7. Conclusions References; 2. Immobilization techniques; 3. Effects of cell immobilization; 4. Immobilized cell bioreactors; 5. Applications of immobilized cell technology; 6. Conclusion; References; 3. New process development; 4. Water-in-oil cultivation technology; 5. PH-sensitive surfactants for water-in-oil cultivation; 6. Conclusions; References; 2. Carboxylic acid fermentation; 3. Integrated fermentation-separation processes; 4. Summary and outlook; References; 3. Fungal metabolites; 4. Pathway manipulation; 5. Conclusions; References; 3. Advantages and unsolved problems; 4. SSF reactors 5. Conclusions |
Altri titoli varianti | Bioprocesses for value added products from renewable resources |
Record Nr. | UNINA-9910784597503321 |
Amsterdam ; ; Boston, MA, : Elsevier, 2006 | ||
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Lo trovi qui: Univ. Federico II | ||
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Bioprocesses for value-added products from renewable resources : new technologies and applications / / edited by Shang-Tian Yang |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, MA, : Elsevier, 2006 |
Descrizione fisica | 1 online resource (685 p.) |
Disciplina |
660.6/3
660.63 |
Altri autori (Persone) | YangShang-Tian |
Soggetto topico |
Biochemical engineering
Biotechnological process control Renewable natural resources |
ISBN |
1-280-72921-X
9786610729210 0-08-046671-0 |
Classificazione | 58.31 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Preface; 2. Applications of genomic and proteomic analyses; 3. Bioprocess analysis and optimization guided by genomic and proteomic analyses: The example of microbial production of 1,3-propanediol; 4. Concluding remarks and outlook; References; 2. Directed evolution tools for diversity generation; 3. Applications of directed evolution tools; 4. Alternatives to directed evolution; 5. Conclusion; Acknowledgements; References; 2. Applications and some examples; 3. Metabolic engineering strategies and limitations; 4. Metabolic engineering methodologies and tools
5. Challenges and new approaches for metabolic engineering 6. Summary; References; 2. Amylase and cellulase classification and mechanisms; 3. Conclusions; Acknowledgment; References; 2. Various types of bioreactors; 3. Effects of process parameters on biological performances; 4. Industrial applications of bioreactors; 5. Trends in bioreactor engineering; Acknowledgments; References; 3. Microfiltration and ultrafiltration processes; 4. Membrane fouling; 5. Applications in biotechnology industries; 5.3. Other applications; 6. Outlook; References; 2. Bacteria; 3. Yeast 4. Fermentation products from bacteria and yeasts 5. Fermentation processes; 6. Conclusion and outlook; References; 2. Fungal cells as biofactories; 3. Hyphal growth and protein secretion; 4. Fungal growth in submerged culture; 5. Effects of cultivation conditions; 6. Effects of morphology on production and secretion; 7. Immobilized fungal cells; 8. Future of filamentous fungal cells as biofactories; References; 2. Production of macromolecules; 3. Production of small molecules; Acknowledgements; References; 2. Modes of micro-algal cultivation; 3. Thraustochytrids 4. High-value products from thraustochytrids 5. Other applications of thraustochytrids; 6. Utilization of renewable resources; 7. Safety issues; 8. Conclusions; 7 References; 2. Enzymatic treatment of biomass components; 3. Further processing of simple renewable molecules for value-added products; 4. New trends in enzymatic bioprocessing; 5. Summary; References; 3. Chiral molecules from hydrolase; 4. Chiral molecules from enzymes requiring cofactors; 5. Improving enantioselectivity by reaction engineering; 6. Improving chiral synthesis by directed evolution and metabolic engineering 7. Conclusions References; 2. Immobilization techniques; 3. Effects of cell immobilization; 4. Immobilized cell bioreactors; 5. Applications of immobilized cell technology; 6. Conclusion; References; 3. New process development; 4. Water-in-oil cultivation technology; 5. PH-sensitive surfactants for water-in-oil cultivation; 6. Conclusions; References; 2. Carboxylic acid fermentation; 3. Integrated fermentation-separation processes; 4. Summary and outlook; References; 3. Fungal metabolites; 4. Pathway manipulation; 5. Conclusions; References; 3. Advantages and unsolved problems; 4. SSF reactors 5. Conclusions |
Altri titoli varianti | Bioprocesses for value added products from renewable resources |
Record Nr. | UNINA-9910822101303321 |
Amsterdam ; ; Boston, MA, : Elsevier, 2006 | ||
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Lo trovi qui: Univ. Federico II | ||
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Hybrid Modelling and Multi- Parametric Control of Bioprocesses / / edited by Christoph Herwig |
Pubbl/distr/stampa | Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2018 |
Descrizione fisica | 1 online resource (148 pages) : illustrations |
Disciplina | 660.6 |
Soggetto topico | Biotechnological process control |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | About the Special Issue Editor -- Preface to "Hybrid Modelling and Multi-Parametric Control of Bioprocesses" -- Karen Schwab, Jennifer Lauber and Friedemann Hesse Fluorometric In Situ Monitoring of an Escherichia coli Cell Factory with Cytosolic Expression of Human Glycosyltransferase GalNAcT2: Prospects and Limitations -- Karen Schwab and Friedemann Hesse Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations -- Maike Kuschel, Flora Siebler and Ralf Takors Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in LargeScale Bioreactors -- Dominik Egger, Ivo Schwedhelm, Jan Hansmann and Cornelia Kasper Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor -- Dominik Egger, Monica Fischer, Andreas Clementi, Volker Ribitsch, Jan Hansmann and Cornelia Kasper Development and Characterization of a Parallelizable Perfusion Bioreactor for 3D Cell Culture -- Dennis Vier, Stefan Wambach, Volker Schnemann and Klaus-Uwe Gollmer Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra fromFed-Batch Fermentation Samples -- Julian Kopp, Christoph Slouka, Sophia Ulonska, Julian Kager, Jens Fricke, Oliver Spadiut and Christoph Herwig Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) -- Rimvydas Simutis and Andreas L ¨ubbert Hybrid Approach to State Estimation for Bioprocess Control -- Thomas Zahel, Lukas Marschall, Sandra Abad, Elena Vasilieva, Daniel Maurer, Eric M. Mueller, Patrick Murphy, Thomas Natschlger, Ccile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1 -- Thomas Zahel, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Sandra Abad, Elena Vasilieva, Daniel Maurer, C´ecile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Integrated Process Modeling-A Process Validation Life Cycle Companion. |
Record Nr. | UNINA-9910598170203321 |
Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2018 | ||
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Lo trovi qui: Univ. Federico II | ||
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Hybrid modelling and multi-parametric control of bioprocesses / / edited by Christoph Herwig |
Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2018 |
Descrizione fisica | 1 online resource (148 pages) : illustrations |
Disciplina | 660.6 |
Soggetto topico | Biotechnological process control |
ISBN | 3-03842-746-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | About the Special Issue Editor -- Preface to "Hybrid Modelling and Multi-Parametric Control of Bioprocesses" -- Karen Schwab, Jennifer Lauber and Friedemann Hesse Fluorometric In Situ Monitoring of an Escherichia coli Cell Factory with Cytosolic Expression of Human Glycosyltransferase GalNAcT2: Prospects and Limitations -- Karen Schwab and Friedemann Hesse Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations -- Maike Kuschel, Flora Siebler and Ralf Takors Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in LargeScale Bioreactors -- Dominik Egger, Ivo Schwedhelm, Jan Hansmann and Cornelia Kasper Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor -- Dominik Egger, Monica Fischer, Andreas Clementi, Volker Ribitsch, Jan Hansmann and Cornelia Kasper Development and Characterization of a Parallelizable Perfusion Bioreactor for 3D Cell Culture -- Dennis Vier, Stefan Wambach, Volker Schnemann and Klaus-Uwe Gollmer Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra fromFed-Batch Fermentation Samples -- Julian Kopp, Christoph Slouka, Sophia Ulonska, Julian Kager, Jens Fricke, Oliver Spadiut and Christoph Herwig Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) -- Rimvydas Simutis and Andreas Lubbert Hybrid Approach to State Estimation for Bioprocess Control -- Thomas Zahel, Lukas Marschall, Sandra Abad, Elena Vasilieva, Daniel Maurer, Eric M. Mueller, Patrick Murphy, Thomas Natschlger, Ccile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1 -- Thomas Zahel, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Sandra Abad, Elena Vasilieva, Daniel Maurer, C´ecile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Integrated Process Modeling-A Process Validation Life Cycle Companion. |
Record Nr. | UNINA-9910688423403321 |
Basel, Switzerland : , : MDPI, , 2018 | ||
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Lo trovi qui: Univ. Federico II | ||
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