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'In silico' simulation of biological processes [[electronic resource] /] / [editors, Gregory Bock and Jamie A. Goode]
'In silico' simulation of biological processes [[electronic resource] /] / [editors, Gregory Bock and Jamie A. Goode]
Pubbl/distr/stampa Chichester, West Sussex, UK ; ; Hoboken, NJ, : John Wiley, 2002
Descrizione fisica 1 online resource (272 p.)
Disciplina 570/.1/13
660.6
Altri autori (Persone) BockGregory
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Biology - Computer simulation
Bioinformatics
Soggetto genere / forma Electronic books.
ISBN 1-280-27080-2
9780470857900
9786610270804
0-470-66805-9
0-470-85790-0
0-470-85789-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 'IN SILICO' SIMULATION OF BIOLOGICAL PROCESSES; Contents; Participants; Chair's introduction; Integrative biological modelling in silico; Discussion; Advances in computing, and their impact on scientific computing; Discussion; From physics to phenomenology. Levels of description and levels of selection; Making sense of complex phenomena in biology; Discussion; On ontologies for biologists: the Gene Ontology-untangling the web; Discussion; General discussion I; Model validation; The KEGG database; Discussion; Bioinformatics of cellular signalling; Discussion; General discussion II
Standards of communicationSemantics and intercommunicability; Imaging-based integrative models of the heart: closing the loop between experiment and simulation; Discussion; General discussion III; Modelling Ca(2+) signalling; The Virtual Cell project; Discussion; Modelling the bacterial chemotaxis receptor complex; The heart cell in silico: successes, failures and prospects; Discussion; Discussion; General discussion IV; The IUPS Physiome Project; Discussion; Using in silico biology to facilitate drug development; Discussion; Final discussion; Is there a theoretical biology?
Index of contributorsSubject index
Record Nr. UNINA-9910143231003321
Chichester, West Sussex, UK ; ; Hoboken, NJ, : John Wiley, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
'In silico' simulation of biological processes [[electronic resource] /] / [editors, Gregory Bock and Jamie A. Goode]
'In silico' simulation of biological processes [[electronic resource] /] / [editors, Gregory Bock and Jamie A. Goode]
Pubbl/distr/stampa Chichester, West Sussex, UK ; ; Hoboken, NJ, : John Wiley, 2002
Descrizione fisica 1 online resource (272 p.)
Disciplina 570/.1/13
660.6
Altri autori (Persone) BockGregory
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Biology - Computer simulation
Bioinformatics
ISBN 1-280-27080-2
9780470857900
9786610270804
0-470-66805-9
0-470-85790-0
0-470-85789-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 'IN SILICO' SIMULATION OF BIOLOGICAL PROCESSES; Contents; Participants; Chair's introduction; Integrative biological modelling in silico; Discussion; Advances in computing, and their impact on scientific computing; Discussion; From physics to phenomenology. Levels of description and levels of selection; Making sense of complex phenomena in biology; Discussion; On ontologies for biologists: the Gene Ontology-untangling the web; Discussion; General discussion I; Model validation; The KEGG database; Discussion; Bioinformatics of cellular signalling; Discussion; General discussion II
Standards of communicationSemantics and intercommunicability; Imaging-based integrative models of the heart: closing the loop between experiment and simulation; Discussion; General discussion III; Modelling Ca(2+) signalling; The Virtual Cell project; Discussion; Modelling the bacterial chemotaxis receptor complex; The heart cell in silico: successes, failures and prospects; Discussion; Discussion; General discussion IV; The IUPS Physiome Project; Discussion; Using in silico biology to facilitate drug development; Discussion; Final discussion; Is there a theoretical biology?
Index of contributorsSubject index
Record Nr. UNINA-9910830290003321
Chichester, West Sussex, UK ; ; Hoboken, NJ, : John Wiley, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
'In silico' simulation of biological processes / / [editors, Gregory Bock and Jamie A. Goode]
'In silico' simulation of biological processes / / [editors, Gregory Bock and Jamie A. Goode]
Pubbl/distr/stampa Chichester, West Sussex, UK ; ; Hoboken, NJ, : John Wiley, 2002
Descrizione fisica 1 online resource (viii, 262 pages) : illustrations
Disciplina 570/.1/13
660.6
Altri autori (Persone) BockGregory
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Biology - Computer simulation
Bioinformatics
Biological models
ISBN 9786610270804
9781280270802
1280270802
9780470668054
0470668059
9780470857908
0470857900
9780470857892
0470857897
9780470857900
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Integrative biological modelling in silico / Andrew D. McCulloch and Gary Huber -- Advances in computing, and their impact on scientific computing / Mike Giles -- From physics to phenomenology : levels of description and levels of selection / David Krakauer -- Making sense of complex phenomena in biology / Philip K. Maini -- On ontologies for biologists : the Gene Ontology : untangling the web / Michael Ashburner and Suzanna Lewis -- Model validation -- The KEGG database / Minoru Kanehisa -- Bioinformatics of cellular signalling / Shankar Subramaniam and the Bioinformatics Core Laboratory -- Imaging-based integrative models of the heart : closing the loop between experiment and simulation / Raimond L. Winslow, Patrick Helm, William Baumgartner, Srinivas Peddi, Tilak Ratnanather, Elliot McVeigh and Michael I. Miller -- Modelling Ca2 signalling -- The Virtual Cell project / Leslie M. Loew -- Modelling the bacterial chemotaxis receptor complex / Thomas Simon Shimizu and Dennis Bray -- The heart cell in silico : successes, failures and prospects / Denis Noble -- The IUPS Physiome Project / P.J. Hunter, P.M.F. Nielsen and D. Bullivant -- Using in silico biology to facilitate drug development / Jeremy M. Levin, R. Christian Penland, Andrew T. Stamps and Carolyn R. Cho -- Is there a 'theoretical biology'?
Record Nr. UNINA-9911019144503321
Chichester, West Sussex, UK ; ; Hoboken, NJ, : John Wiley, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Complex biological systems : adaptation and tolerance to extreme environments / / edited by Karl Y. Biel, Vladislav G. Soukhovolsky, Irina R. Fomina
Complex biological systems : adaptation and tolerance to extreme environments / / edited by Karl Y. Biel, Vladislav G. Soukhovolsky, Irina R. Fomina
Pubbl/distr/stampa Hoboken, New Jersey : , : Scriverner Publishing : , : Wiley, , 2018
Descrizione fisica 1 online resource (606 pages)
Disciplina 610.113
Collana THEi Wiley ebooks.
Soggetto topico Medicine - Computer simulation
Biology - Computer simulation
ISBN 1-119-51033-3
1-119-51039-2
1-119-51037-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910555147403321
Hoboken, New Jersey : , : Scriverner Publishing : , : Wiley, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Complex biological systems : adaptation and tolerance to extreme environments / / edited by Karl Y. Biel, Vladislav G. Soukhovolsky, Irina R. Fomina
Complex biological systems : adaptation and tolerance to extreme environments / / edited by Karl Y. Biel, Vladislav G. Soukhovolsky, Irina R. Fomina
Pubbl/distr/stampa Hoboken, New Jersey : , : Scriverner Publishing : , : Wiley, , 2018
Descrizione fisica 1 online resource (606 pages)
Disciplina 610.113
Collana THEi Wiley ebooks.
Soggetto topico Medicine - Computer simulation
Biology - Computer simulation
ISBN 1-119-51033-3
1-119-51039-2
1-119-51037-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910812890403321
Hoboken, New Jersey : , : Scriverner Publishing : , : Wiley, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Pacific Symposium on Biocomputing 2007 [[electronic resource] ] : Maui, Hawaii, 3-7 January 2007 / / edited by Russ B. Altman ... [et al.]
Pacific Symposium on Biocomputing 2007 [[electronic resource] ] : Maui, Hawaii, 3-7 January 2007 / / edited by Russ B. Altman ... [et al.]
Pubbl/distr/stampa Hackensack, N.J., : World Scientific, c2007
Descrizione fisica xvi, 507 p. : ill
Disciplina 570.15
Altri autori (Persone) AltmanRuss
Soggetto topico Biology - Computer simulation
Biology - Mathematical models
Molecular biology - Computer simulation
Molecular biology - Mathematical models
Soggetto genere / forma Electronic books.
ISBN 1-281-91203-4
9786611912031
981-277-243-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Protein interactions and diseases. Session introduction / Maricel Kann ... [et al.]. Graph kernels for disease outcome prediction from protein-protein interaction networks / Karsten M. Borgwardt ... [et al.]. Chalkboard: ontology-based pathway modeling and qualitative inference of disease mechanisms / Daniel L. Cook, Jesse C. Wiley, and John H. Gennari. Mining gene-disease relationships from biomedical literature weighting protein-protein interactions and connectivity measures / Graciela Gonzalez ... [et al.]. Predicting structure and dynamics of loosely-ordered protein complexes: influenza hemagglutinin fusion peptide / Peter M. Kasson and Vijay S. Pande. Protein interactions and disease phenotypes in the ABC transporter superfamily / Libusha Kelly, Rachel Karchin, and Andrej Sali. LTHREADER: prediction of Ligand-receptor interactions using localized threading / Vinay Pulim, Jadwiga Bienkowska, and Bonnie Berger. Discovery of protein interaction networks shared by diseases / Lee Sam ... [et al.]. An iterative algorithm for metabolic network-based drug target identification / Padmavati Sridhar, Tamer Kahveci, and Sanjay Ranka. Transcriptional interactions during smallpox infection and identification of early infection biomarkers / Willy A. Valdivia-Granda, Maricel G. Kann, and Jose Malaga -- Computational approaches to metabolomics. Session introduction / David S. Wishart and Russell Greiner. Leveraging latent information in NMR spectra for robust predictive models / David Chang, Aalim Weljie, and Jack Newton. Bioinformatics data profiling tools: a prelude to metabolic profiling / Natarajan Ganesan, Bala Kalyanasundaram, and Mahe Velauthapllai. Comparative QSAR analysis of bacterial, fungal, plant and human metabolites / Emre Karakoc, S. Cenk Sahinalp, and Artem Cherkasov. BioSpider: a web server for automating metabolome annotations / Craig Knox ... [et al.]. New bioinformatics resources for metabolomics / John L. Markley ... [et al.]. Setup X - a public study design database for metabolomic projects / Martin Scholz and Oliver Fiehn. Comparative metabolomics of breast cancer / Chen Yang ... [et al.]. Metabolic flux profiling of reaction modules in liver drug transformation / Jeongah Yoon and Kyongbum Lee -- New frontiers in biomedical text mining. Session introduction / Pierre Zweigenbaum ... [et al.]. Extracting semantic predications from medline citations for pharmacogenomics / Caroline B. Ahlers ... [et al.]. Annotating genes using textual patterns / Ali Cakmak and Gultekin Ozsoyoglu. A fault model for ontology mapping, alignment, and linking systems / Helen L. Johnson, K. Bretonnel Cohen, and Lawrence Hunter. Integrating natural language processing with flybase curation / Nikiforos Karamanis Y. ... [et al.]. A stacked graphical model for associating sub-images with sub-captions / Zhenzhen Kou, William W. Cohen, and Robert F. Murphy. GeneRIF quality assurance as summary revision / Zhiyong Lu, K. Bretonnel Cohen, and Lawrence Hunter. Evaluating the automatic mapping of human gene and protein mentions to unique identifiers / Alexander A. Morgan ... [et al.]. Multiple approaches to fine-grained indexing of the biomedical literature / Aurelie Neveol ... [et al.]. Mining patents using molecular similarity search / James Rhodes ... [et al.]. Discovering implicit associations between genes and hereditary diseases / Kazuhiro Seki and Javed Mostafa. A cognitive evaluation of four online search engines for answering definitional questions posed by physicians / Hong Yu and David Kaufman -- Biodiversity informatics: managing knowledge beyond humans and model organisms. Session introduction / Indra Neil Sarkar. Biomediator data integration and inference for functional annotation of anonymous sequences / Eithon Cadag ... [et al.]. Absent sequences: nullomers and primes / Greg Hampikian and Tim Andersen. An anatomical ontology for amphibians / Anne M. Maglia ... [et al.]. Recommending pathway genes using a compendium of clustering solutions / David M. Ng, Marcos H. Woehrmann, and Joshua M. Stuart. Semi-automated XML markup of biosystematic legacy literature with the Goldengate editor / Guido Sautter, Klemens B�ohm, and Donat Agosti -- Computational proteomics: high-throughput analysis for systems biology. Session introduction / William Cannon and Bobbie-Jo Webb-Robertson. Advancement in protein inference from shotgun proteomics using peptide detectability / Pedro Alves ... [et al.]. Mining tandem mass spectral data to develop a more accurate mass error model for peptide identification / Yan Fu ... [et al.]. Assessing and combining reliability of protein interaction sources / Sonia Leach ... [et al.]. Probabilistic modeling of systematic errors in two-hybrid experiments / David Sontag, Rohit Singh, and Bonnie Berger. Prospective exploration of biochemical tissue composition via imaging mass spectrometry guided by principal component analysis / Raf Van de Plas ... [et al.] -- DNA-protein interactions: integrating structure, sequence, and function. Session introduction / Martha L. Bulyk ... [et al.]. Discovering motifs with transcription factor domain knowledge / Henry C. M. Leung, Francis Y. L. Chin, and Bethany M. Y. Chan. Ab initio prediction of transcription factor binding sites / L. Angela Liu and Joel S. Bader. Comparative pathway annotation with protein-DNA interaction and operon information via graph tree decomposition / Jizhen Zhao, Dongsheng Che, and Liming Cai.
Record Nr. UNINA-9910451938803321
Hackensack, N.J., : World Scientific, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Pacific Symposium on Biocomputing 2007 [[electronic resource] ] : Maui, Hawaii, 3-7 January 2007 / / edited by Russ B. Altman ... [et al.]
Pacific Symposium on Biocomputing 2007 [[electronic resource] ] : Maui, Hawaii, 3-7 January 2007 / / edited by Russ B. Altman ... [et al.]
Pubbl/distr/stampa Hackensack, N.J., : World Scientific, c2007
Descrizione fisica xvi, 507 p. : ill
Disciplina 570.15
Altri autori (Persone) AltmanRuss
Soggetto topico Biology - Computer simulation
Biology - Mathematical models
Molecular biology - Computer simulation
Molecular biology - Mathematical models
ISBN 1-281-91203-4
9786611912031
981-277-243-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Protein interactions and diseases. Session introduction / Maricel Kann ... [et al.]. Graph kernels for disease outcome prediction from protein-protein interaction networks / Karsten M. Borgwardt ... [et al.]. Chalkboard: ontology-based pathway modeling and qualitative inference of disease mechanisms / Daniel L. Cook, Jesse C. Wiley, and John H. Gennari. Mining gene-disease relationships from biomedical literature weighting protein-protein interactions and connectivity measures / Graciela Gonzalez ... [et al.]. Predicting structure and dynamics of loosely-ordered protein complexes: influenza hemagglutinin fusion peptide / Peter M. Kasson and Vijay S. Pande. Protein interactions and disease phenotypes in the ABC transporter superfamily / Libusha Kelly, Rachel Karchin, and Andrej Sali. LTHREADER: prediction of Ligand-receptor interactions using localized threading / Vinay Pulim, Jadwiga Bienkowska, and Bonnie Berger. Discovery of protein interaction networks shared by diseases / Lee Sam ... [et al.]. An iterative algorithm for metabolic network-based drug target identification / Padmavati Sridhar, Tamer Kahveci, and Sanjay Ranka. Transcriptional interactions during smallpox infection and identification of early infection biomarkers / Willy A. Valdivia-Granda, Maricel G. Kann, and Jose Malaga -- Computational approaches to metabolomics. Session introduction / David S. Wishart and Russell Greiner. Leveraging latent information in NMR spectra for robust predictive models / David Chang, Aalim Weljie, and Jack Newton. Bioinformatics data profiling tools: a prelude to metabolic profiling / Natarajan Ganesan, Bala Kalyanasundaram, and Mahe Velauthapllai. Comparative QSAR analysis of bacterial, fungal, plant and human metabolites / Emre Karakoc, S. Cenk Sahinalp, and Artem Cherkasov. BioSpider: a web server for automating metabolome annotations / Craig Knox ... [et al.]. New bioinformatics resources for metabolomics / John L. Markley ... [et al.]. Setup X - a public study design database for metabolomic projects / Martin Scholz and Oliver Fiehn. Comparative metabolomics of breast cancer / Chen Yang ... [et al.]. Metabolic flux profiling of reaction modules in liver drug transformation / Jeongah Yoon and Kyongbum Lee -- New frontiers in biomedical text mining. Session introduction / Pierre Zweigenbaum ... [et al.]. Extracting semantic predications from medline citations for pharmacogenomics / Caroline B. Ahlers ... [et al.]. Annotating genes using textual patterns / Ali Cakmak and Gultekin Ozsoyoglu. A fault model for ontology mapping, alignment, and linking systems / Helen L. Johnson, K. Bretonnel Cohen, and Lawrence Hunter. Integrating natural language processing with flybase curation / Nikiforos Karamanis Y. ... [et al.]. A stacked graphical model for associating sub-images with sub-captions / Zhenzhen Kou, William W. Cohen, and Robert F. Murphy. GeneRIF quality assurance as summary revision / Zhiyong Lu, K. Bretonnel Cohen, and Lawrence Hunter. Evaluating the automatic mapping of human gene and protein mentions to unique identifiers / Alexander A. Morgan ... [et al.]. Multiple approaches to fine-grained indexing of the biomedical literature / Aurelie Neveol ... [et al.]. Mining patents using molecular similarity search / James Rhodes ... [et al.]. Discovering implicit associations between genes and hereditary diseases / Kazuhiro Seki and Javed Mostafa. A cognitive evaluation of four online search engines for answering definitional questions posed by physicians / Hong Yu and David Kaufman -- Biodiversity informatics: managing knowledge beyond humans and model organisms. Session introduction / Indra Neil Sarkar. Biomediator data integration and inference for functional annotation of anonymous sequences / Eithon Cadag ... [et al.]. Absent sequences: nullomers and primes / Greg Hampikian and Tim Andersen. An anatomical ontology for amphibians / Anne M. Maglia ... [et al.]. Recommending pathway genes using a compendium of clustering solutions / David M. Ng, Marcos H. Woehrmann, and Joshua M. Stuart. Semi-automated XML markup of biosystematic legacy literature with the Goldengate editor / Guido Sautter, Klemens B�ohm, and Donat Agosti -- Computational proteomics: high-throughput analysis for systems biology. Session introduction / William Cannon and Bobbie-Jo Webb-Robertson. Advancement in protein inference from shotgun proteomics using peptide detectability / Pedro Alves ... [et al.]. Mining tandem mass spectral data to develop a more accurate mass error model for peptide identification / Yan Fu ... [et al.]. Assessing and combining reliability of protein interaction sources / Sonia Leach ... [et al.]. Probabilistic modeling of systematic errors in two-hybrid experiments / David Sontag, Rohit Singh, and Bonnie Berger. Prospective exploration of biochemical tissue composition via imaging mass spectrometry guided by principal component analysis / Raf Van de Plas ... [et al.] -- DNA-protein interactions: integrating structure, sequence, and function. Session introduction / Martha L. Bulyk ... [et al.]. Discovering motifs with transcription factor domain knowledge / Henry C. M. Leung, Francis Y. L. Chin, and Bethany M. Y. Chan. Ab initio prediction of transcription factor binding sites / L. Angela Liu and Joel S. Bader. Comparative pathway annotation with protein-DNA interaction and operon information via graph tree decomposition / Jizhen Zhao, Dongsheng Che, and Liming Cai.
Record Nr. UNINA-9910778260903321
Hackensack, N.J., : World Scientific, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Pacific Symposium on Biocomputing 2014, Kohala Coast, Hawaii, USA, 3-7 January 2014 / / edited by Russ B. Altman, Stanford University, USA [and 5 others]
Pacific Symposium on Biocomputing 2014, Kohala Coast, Hawaii, USA, 3-7 January 2014 / / edited by Russ B. Altman, Stanford University, USA [and 5 others]
Autore Russ B Altman
Pubbl/distr/stampa World Scientific Publishing Co, 2013
Descrizione fisica 1 online resource (vii, 426 pages) : illustrations (some color)
Disciplina 570.113
Collana Gale eBooks
Soggetto topico Biology - Mathematical models
Biology - Computer simulation
Molecular biology - Mathematical models
Molecular biology - Computer simulation
Soggetto non controllato Protein Interactions
Metabolomics
Biocomputing
Computational Genetics
Ontology
Computational Proteomics
Bioinformatics
ISBN 981-4583-22-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cancer panomics: Computational methods and infrastructure for integrative analysis of cancer high-throughput "OMICS" data. Session introduction / Soren Brunak ... [et al.] -- Tumor haplotype assembly algorithms for cancer genomics / Derek Aguiar, Wendy S.W. Wong, Sorin Istrail -- Extracting significant sample-specific cancer mutations using their protein interactions / Liviu Badea -- The stream algorithm: Computationally efficient ridge-regression via Bayesian model averaging, and applications to pharmacogenomic prediction of cancer cell line sensitivity / Elias Chaibub Neto ... [et al.] -- Sharing information to reconstruct patient-specific pathways in heterogeneous diseases / Anthony Gitter ... [et al.] -- Detecting statistical interaction between somatic mutational events and germline variation from next-generation sequence data / Hao Hu, Chad D. Huff -- Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data / In Sock Jang ... [et al.] -- Integrative analysis of two cell lines derived from a non-small-lung cancer patient - A panomics approach / Oleg Mayba ... [et al.] -- An integrated approach to blood-based cancer diagnosis and biomarker discovery / Martin Renqiang Min ... [et al.] -- Multiplex meta-analysis of medulloblastoma expression studies with external controls / Alexander A. Morgan ... [et al.] -- Computational approaches to drug repurposing and pharmacology. Session introduction / S. Joshua Swamidass ... [et al.] -- Challenges in secondary analysis of high throughput screening data / Aurora S. Blucher, Shannon K. McWeeney -- Drug intervention response predictions with paradigm (DIRPP) identifies drug resistant cancer cell lines and pathway mechanisms of resistance / Douglas Brubaker ... [et al.] -- Anti-infectious drug repurposing using an integrated chemical genomics and structural systems biology approach / Clara Ng ... [et al.] -- Drug-target interaction prediction by integrating chemical, genomic, functional and pharmacological data / Fan Yang, Jinbo Xu, Jianyang Zeng -- Prediction of off-target drug effects through data fusion / Emmanuel R. Yera, Ann E. Cleves, Ajay N. Jain -- Exploring the pharmacogenomics knowledge base (PharmGKB) for repositioning breast cancer drugs by leveraging web ontology language (OWL) and cheminformatics approaches / Qian Zhu ... [et al.] -- Detecting and characterizing pleiotropy: New methods for uncovering the connection between the complexity of genomic architecture and multiple phenotypes. Session introduction / Anna L. Tyler, Dana C. Crawford, Sarah A. Pendergrass -- Using the bipartite human phenotype network to reveal pleiotropy and epistasis beyond the gene / Christian Darabos, Samantha H. Harmon, Jason H. Moore -- Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield personalized medicine research project biobank / Molly A. Hall ... [et al.] -- Dissection of complex gene expression using the combined analysis of pleiotropy and epistasis / Vivek M. Philip, Anna L. Tyler, Gregory W. Carter -- Personalized medicine: From genotypes and molecular phenotypes towards therapy. Session introduction / Jennifer Listgarten ... [et al.] -- PATH-SCAN: A reporting tool for identifying clinically actionable variants / Roxana Daneshjou ... [et al.] -- Imputation-based assessment of next generation rare exome variant arrays / Alicia R. Martin ... [et al.] -- Utilization of an EMR-biorepository to identify the genetic predictors of calcineurin-inhibitor toxicity in heart transplant recipients/ Matthew Oetjens ... [et al.] -- Robust reverse engineering of dynamic gene networks under sample size heterogeneity / Ankur P. Parikh, Wei Wu, Eric P. Xing -- Variant priorization and analysis incorporating problematic regions of the genome / Anil Patwardhan ... [et al.] -- Bags of words models of epitope sets: HIV viral load regression with counting grids / Alessandro Perina, Pietro Lovato, Nebojsa Jojic -- Joint association discovery and diagnosis of Alzheimer's disease by supervised heterogeneous multiview learning / Shandian Zhe ... [et al.] -- Text and data mining for biomedical discover. Session introduction / Graciela H. Gonzalez ... [et al.] -- Vector quantization kernels for the classification of protein sequences and structures / Wyatt T. Clark, Predrag Radivojac -- Combining Heterogenous data for prediction of disease related and pharmacogenes / Christopher S. Funk, Lawrence E. Hunter, K. Bretonnel Cohen -- A novel profile biomarker diagnosis for mass spectral proteomics / Henry Han -- Towards pathway curation through literature mining - A case study using PharmGKB / Ravikumar K.E., Kavishwar B. Wagholikar, Hongfang Liu -- Sparse generalized functional linear model for predicting remission status of depression patients / Yashu Liu ... [et al.] -- Development of a data-mining algorithm to identify ages at reproductive milestones in electronic medical records / Jennifer Malinowski, Eric Farber-Eger, Dana C. Crawford -- An efficient algorithm to integrate network and attribute data for gene function prediction / Shankar Vembu, Quaid Morris -- Matrix factorization-based data fusion for gene function prediction in Baker's yeast and slime mold / Marinka Zitnik, Blaz Zupan -- Workshops. Applications of bioinformatics to non-coding RNAs in the era of next-generation sequencing / Chao Cheng, Jason Moore, Casey Greene -- Building the next generation of quantitative biologists / Kristine A. Pattin ... [et al.] -- Uncovering the etiology of autism spectrum disorders: Genomics, bioinformatics, environment, data collection and exploration, and future possibilities / Sarah A. Pendergrass, Santhosh Girirajan, Scott Selleck.
Record Nr. UNINA-9910140405603321
Russ B Altman  
World Scientific Publishing Co, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Pacific Symposium on Biocomputing 2020 : Kohala Coast, Hawaii, USA, 3-7 January 2020 / / edited by Russ B. Altman ... [et al.]
Pacific Symposium on Biocomputing 2020 : Kohala Coast, Hawaii, USA, 3-7 January 2020 / / edited by Russ B. Altman ... [et al.]
Autore Russ B Altman
Pubbl/distr/stampa Singapore, : World Scientific, [2019]
Descrizione fisica 1 online resource (500 p.) : ill
Disciplina 570.151
Altri autori (Persone) AltmanRuss
Soggetto topico Biology - Mathematical models
Biology - Computer simulation
Soggetto genere / forma Conference papers and proceedings.
ISBN 981-12-1563-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Session introduction: Artificial intelligence for enhancing clinical medicine / Roxana Daneshjou ... [et al.] -- Predicting longitudinal outcomes of Alzheimer's disease via a tensor-based joint classification and regression model / Lodewijk Brand ... [et al.] -- Robustly extracting medical knowledge from EHRs: a case study of learning a health knowledge graph / Irene Y. Chen ... [et al.] -- Increasing clinical trial accrual via automated matching of biomarker criteria / Jessica W. Chen ... [et al.] -- Addressing the credit assignment problem in treatment outcome prediction using temporal difference learning / Sahar Harati ... [et al.] -- Multiclass disease classification from microbial whole-community metagenomes / Saad Khan and Libusha Kelly -- LitGen: genetic literature recommendation guided by human explanations / Allen Nie ... [et al.] -- From genome to phenome: predicting multiple cancer phenotypes based on somatic genomic alterations via the genomic impact transformer / Yifeng Tao ... [et al.] -- Automated phenotyping of patients wsith non-alcolholic fatty liver disease reveals clinically relevant disease subtypes / Maxence Vandromme [et al.] -- Monitoring ICU mortality risk with a long short-term memory recurrent neural network / Ke Yu ... [et al.] -- Multilevel self-attention model and its use on medical risk prediction / Xianlong Zeng ... [et al.] -- Identifying transitional high cost users from unstructured patient profiles written by primary care physicians / Haoran Zhang ... [et al.] --Obtaining dual-energy computed tomography (CT) information from a single-energy CT image for quantitative imaging analysis of living subjects by using deep learning / Wei Zhao ... [et al.] -- On the importance of computational biology and bioinformatics to the origins and rapid progression of the intrinsically disordered proteins field / Lukasz Kurgan ... [et al.] -- Many-to-one binding by intrinsically disordered problem regions / Wei-Lun Alterovitz ... [et al.] -- Disordered function conjunction: on the in-silico function annotation of intrinsically disordered regions / Sina Ghadermarzi ... [et al.] -- De novo ensemble modeling suggests that AP2-binding to disordered regions can increase steric volume of Epsin but not Eps15 / N. Suhas Jagannathan ... [et al.] -- Modulation of p53 transactivation domain conformations by ligand binding and cancer-associated mutations / Xiaorong Liu and Jianhan Chen -- Exploring relationship between the density of charged tracts within disordered regions and phase separation / Ramiz Somjee, Diana M. Mitrea and Richard W. Kriwacki -- Session introduction: Mutational signatures: etiology, properties, and role in cancer / Mark D.M. Leiserson, Teresa M. Przytycka and Roded Sharan -- PhySigs: phylogenetic inference of mutational signature dynamics / Sarah Chistensen, Mark D.M. Leiserson and Mohammed El-Kebir -- TrackSigFreq: subclonal reconstructions based on mutation signatures and allele frequencies / Caitlin F. Harrigan ... [et al.] -- Impact of mutational signatures on microRNA and their response elements / Eirini Stamoulakatou ... [et al.] -- DNA repair footprint uncovers contribution of DNA repair mechanism to mutational signatures / Damian Wojtowicz ... [et al.] -- Genome gerrymandering: optimal division of the genome into regions with cancer type specific differences in mutation rates / Adamo Young ... [et al.] -- Ongoing challenges and innovative approaches for recognizing pattern across large-scale, integrative biomedical datasets / Shilpa Nadimpalli ... [et al.] -- Clinical concept embeddings learned from massive sources of multimodal medical data / Andrew L. Beam ... [et al.] -- Assessment of imputation methods for missing gene expression data in meta-analysis of distinct cohorts of tuberculosis patients / Carly A. Bobak ... [et al.] -- Towards identifying drug side effects from social media using active learning and crowd sourcing / Sophie Burkhardt ... [et al.] -- Microvascular dynamics from 4D microscopy using temporal segmentation / Shir Gur ... [et al.] -- Using transcriptional signatures to find cancer drivers with LURE / David Haan ... [et al.] -- and other papers.
Record Nr. UNINA-9910367718703321
Russ B Altman  
Singapore, : World Scientific, [2019]
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