top

  Info

  • Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.

  Info

  • Utilizzare questo link per rimuovere la selezione effettuata.
Bioenergetics 3 [[electronic resource] /] / David G. Nicholls, Stuart J. Ferguson
Bioenergetics 3 [[electronic resource] /] / David G. Nicholls, Stuart J. Ferguson
Autore Nicholls David G
Edizione [[3rd ed.].]
Pubbl/distr/stampa San Diego, Calif., : Academic Press, c2002
Descrizione fisica 1 online resource (331 p.)
Disciplina 572/.43
Altri autori (Persone) FergusonS. J <1949-> (Stuart John)
Soggetto topico Bioenergetics
Biological transport, Active
Soggetto genere / forma Electronic books.
ISBN 1-281-03340-5
9786611033408
0-08-052793-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Bioenergetics 3; Copyright Page; CONTENTS; Preface; Note to the reader; Glossary; CHAPTER 1. CHEMIOSMOTIC ENERGY TRANSDUCTION; 1.1 Introduction; 1.2 The chemiosmotic theory: fundamentals; 1.3 The basic morphology of energy-transducing membranes; 1.4 Overview; CHAPTER 2. ION TRANSPORT ACROSS ENERGY-CONSERVING MEMBRANES; 2.1 Introduction; 2.2 The classification of ion transport; 2.3 Bilayer-mediated transport; 2.4 Protein-catalysed transport; 2.5 Swelling and the co-ordinate movement of ions across membranes; CHAPTER 3. QUANTITATIVE BIOENERGETICS: THE MEASUREMENT OF DRIVING FORCES
3.1 Introduction3.2 Gibbs energy and displacement from equilibrium; 3.3 Oxidation-reduction (redox) potentials; 3.4 Ion electrochemical potential differences; 3.5 Photons; 3.6 Bioenergetic interconversions and thermodynamic constraints on their stoichiometries; 3.7 The equilibrium distributions of ions, weak acids and weak bases; 3.8 Membrane potentials, diffusion potentials, Donnan potentials and surface potentials; CHAPTER 4. THE CHEMIOSMOTIC PROTON CIRCUIT; 4.1 Introduction; 4.2 The measurement of protonmotive force; 4.3 The stoichiometry of proton extrusion by the respiratory chain
4.4 The stoichiometry of proton uptake by the ATP synthase4.5 Proton current and respiratory control; 4.6 Proton conductance; 4.7 Mitochondria1 respiration rate and metabolic control analysis; 4.8 Overall parameters of energy transduction; 4.9 Reversed electron transfer and the proton circuit driven by ATP hydrolysis; 4.10 ATP synthesis driven by an artificial protonmotive force; 4.11 Kinetic competence of Δp in the proton circuit; 4.12 Light-dependent ATP synthesis by bovine heart ATP synthase; CHAPTER 5. RESPIRATORY CHAINS; 5.1 Introduction
5.2 Components of the mitochondria1 respiratory chain5.3 The sequence of redox carriers in the respiratory chain; 5.4 The mechanism of electron transfer; 5.5 Proton translocation by the respiratory chain: 'loops', ' conformational pumps' or both?; 5.6 Complex I (NADH-UQ oxidoreductase); 5.7 Delivering electrons to ubiquinone without proton translocation; 5.8 Ubiquinone and complex III (bc1 or UQ-CYT c oxidoreductase); 5.9 Cytochrome c and complex IV (cytochrome c oxidase; ferrocytochrome c: O2 oxidoreductase)
5.10 Overall proton and charge movements catalysed by the respiratory chain: correlation with the P/O ratio5.11 Superoxide production by complexes I and III; 5.12 Oxidative stress; 5.13 The nicotinamide nucleotide transhydrogenase; 5.14 Electron transport in mitochondria of non-mammalian cells; 5.15 Bacterial respiratory chains; CHAPTER 6. PHOTOSYNTHETIC GENERATORS OF PROTONMOTIVE FORCE; 6.1 Introduction; 6.2 The light reaction of photosynthesis in Rhodobacter sphaeroides and related organisms; 6.3 The generation by illumination or respiration of Δp in photosynthetic bacteria
6.4 The electron-transfer and light-capture pathway in green plants and algae
Record Nr. UNINA-9910457980403321
Nicholls David G  
San Diego, Calif., : Academic Press, c2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Bioenergetics 3 [[electronic resource] /] / David G. Nicholls, Stuart J. Ferguson
Bioenergetics 3 [[electronic resource] /] / David G. Nicholls, Stuart J. Ferguson
Autore Nicholls David G
Edizione [[3rd ed.].]
Pubbl/distr/stampa San Diego, Calif., : Academic Press, c2002
Descrizione fisica 1 online resource (331 p.)
Disciplina 572/.43
Altri autori (Persone) FergusonS. J <1949-> (Stuart John)
Soggetto topico Bioenergetics
Biological transport, Active
ISBN 1-281-03340-5
9786611033408
0-08-052793-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Bioenergetics 3; Copyright Page; CONTENTS; Preface; Note to the reader; Glossary; CHAPTER 1. CHEMIOSMOTIC ENERGY TRANSDUCTION; 1.1 Introduction; 1.2 The chemiosmotic theory: fundamentals; 1.3 The basic morphology of energy-transducing membranes; 1.4 Overview; CHAPTER 2. ION TRANSPORT ACROSS ENERGY-CONSERVING MEMBRANES; 2.1 Introduction; 2.2 The classification of ion transport; 2.3 Bilayer-mediated transport; 2.4 Protein-catalysed transport; 2.5 Swelling and the co-ordinate movement of ions across membranes; CHAPTER 3. QUANTITATIVE BIOENERGETICS: THE MEASUREMENT OF DRIVING FORCES
3.1 Introduction3.2 Gibbs energy and displacement from equilibrium; 3.3 Oxidation-reduction (redox) potentials; 3.4 Ion electrochemical potential differences; 3.5 Photons; 3.6 Bioenergetic interconversions and thermodynamic constraints on their stoichiometries; 3.7 The equilibrium distributions of ions, weak acids and weak bases; 3.8 Membrane potentials, diffusion potentials, Donnan potentials and surface potentials; CHAPTER 4. THE CHEMIOSMOTIC PROTON CIRCUIT; 4.1 Introduction; 4.2 The measurement of protonmotive force; 4.3 The stoichiometry of proton extrusion by the respiratory chain
4.4 The stoichiometry of proton uptake by the ATP synthase4.5 Proton current and respiratory control; 4.6 Proton conductance; 4.7 Mitochondria1 respiration rate and metabolic control analysis; 4.8 Overall parameters of energy transduction; 4.9 Reversed electron transfer and the proton circuit driven by ATP hydrolysis; 4.10 ATP synthesis driven by an artificial protonmotive force; 4.11 Kinetic competence of Δp in the proton circuit; 4.12 Light-dependent ATP synthesis by bovine heart ATP synthase; CHAPTER 5. RESPIRATORY CHAINS; 5.1 Introduction
5.2 Components of the mitochondria1 respiratory chain5.3 The sequence of redox carriers in the respiratory chain; 5.4 The mechanism of electron transfer; 5.5 Proton translocation by the respiratory chain: 'loops', ' conformational pumps' or both?; 5.6 Complex I (NADH-UQ oxidoreductase); 5.7 Delivering electrons to ubiquinone without proton translocation; 5.8 Ubiquinone and complex III (bc1 or UQ-CYT c oxidoreductase); 5.9 Cytochrome c and complex IV (cytochrome c oxidase; ferrocytochrome c: O2 oxidoreductase)
5.10 Overall proton and charge movements catalysed by the respiratory chain: correlation with the P/O ratio5.11 Superoxide production by complexes I and III; 5.12 Oxidative stress; 5.13 The nicotinamide nucleotide transhydrogenase; 5.14 Electron transport in mitochondria of non-mammalian cells; 5.15 Bacterial respiratory chains; CHAPTER 6. PHOTOSYNTHETIC GENERATORS OF PROTONMOTIVE FORCE; 6.1 Introduction; 6.2 The light reaction of photosynthesis in Rhodobacter sphaeroides and related organisms; 6.3 The generation by illumination or respiration of Δp in photosynthetic bacteria
6.4 The electron-transfer and light-capture pathway in green plants and algae
Record Nr. UNINA-9910784528703321
Nicholls David G  
San Diego, Calif., : Academic Press, c2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Channels, carriers, and pumps : an introduction to membrane transport / / Wilfred D. Stein, Thomas Litman
Channels, carriers, and pumps : an introduction to membrane transport / / Wilfred D. Stein, Thomas Litman
Autore Stein Wilfred D.
Edizione [Second edition.]
Pubbl/distr/stampa London, England : , : Academic Press, , 2015
Descrizione fisica 1 online resource (423 p.)
Disciplina 572.696
Soggetto topico Biological transport - Regulation
Biological transport, Active
Soggetto genere / forma Electronic books.
ISBN 0-12-416583-4
0-12-416579-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Channels, Carriers, and Pumps; Copyright Page; Dedications; Contents; Preface to the First Edition; Preface to the Second Edition; List of Symbols; 1 Structural Basis of Movement Across Cell Membranes; 1.1 Membrane Structure: Electron Microscopy of Biological Membranes; 1.2 Chemical Composition of Biological Membranes; 1.2.1 Membrane Lipids; 1.2.2 Membrane Proteins; 1.2.3 Membrane Carbohydrates; 1.3 Membrane Phospholipid Structures and Their Self-Assembly; 1.4 Phase Transitions in Biological Membranes; 1.5 Membrane Proteins: Their Structure and Arrangement
1.5.1 Proteins That Span the Membrane Only Once1.5.2 Proteins That Span the Membrane More Than Once; 1.6 Synthesis of Membrane Proteins; 1.7 Quantitation of Membrane Dynamics; 1.8 Traffic Across the Plasma Membrane; 1.9 The Cell Membrane as a Barrier and as a Passage; Suggested Readings; General; Membrane Structure; Membrane Lipids; Liposomes; Membrane Proteins; Membrane Dynamics; Glycophorin; Lactose Permease; Hydropathy Plots; Membrane Protein Structure; Synthesis of Membrane Proteins; Endocytosis, Membrane Turnover; Clathrin-Coated Pits and Caveolae; Lipid Rafts; Cytoskeleton
2 Simple Diffusion of Nonelectrolytes and Ions2.1 Diffusion as a Random Walk; 2.2 The Electrical Force Acting on an Ion; 2.3 Permeability Coefficients and Partition Coefficients; 2.4 Measurement of Permeability Coefficients; 2.5 Analysis of Permeability Data; 2.6 The Membrane as a Hydrophobic Sieve; 2.7 Osmosis and the Diffusion of Water; 2.8 Comparison of Osmotic and Diffusive Flow of Water; Suggested Readings; General; Diffusion as a Random Walk; Chemical Potential; Electrical Potential; Flux Ratio Test; Permeability and Partition Coefficients; Measurement of Permeability Coefficients
NMR and ESRUnstirred Layers; Plant Cell Permeabilities; Membrane as a Hydrophobic Sieve; Osmosis and the Diffusion of Water; Water Channels - The Aquaporins; Electroosmosis and Streaming Potential; 3 Ion Channels Across Cell Membranes; 3.1 The Gramicidin Channel; 3.2 The Acetylcholine Receptor Channel; 3.3 Conductances and Cross-Sectional Areas of Single Channels; 3.4 An Experimental Interlude; 3.4.1 Identification of Channels by Patch-Clamping; 3.4.2 Measurements of Membrane Potential by Using Intracellular Microelectrodes or by Following Dye Distribution
3.5 Diffusion Potentials: Goldman-Hodgkin-Katz Equation3.6 Regulation and Modulation of Channel Opening; 3.6.1 The Potassium Channel of Sarcoplasmic Reticulum; 3.6.2 Sodium and Potassium Channels of Excitable Tissue; 3.6.3 The Cell-to-Cell Channel or Gap Junction; 3.6.4 Regulation and Modulation of Some Other Channels; Suggested Readings; Internet Resources; General; Electrostatic (Born) Free Energy; Gramicidin Channel; Enzyme Kinetics; Acetylcholine Receptor; Cloning and Molecular Biology; Acetylcholine Receptor Structure; Ionic Diffusion; Ligand-gated Ion Channels
Charge Effects on Channel Conductance
Record Nr. UNINA-9910459797303321
Stein Wilfred D.  
London, England : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Channels, carriers, and pumps : an introduction to membrane transport / / Wilfred D. Stein, Thomas Litman
Channels, carriers, and pumps : an introduction to membrane transport / / Wilfred D. Stein, Thomas Litman
Autore Stein Wilfred D.
Edizione [Second edition.]
Pubbl/distr/stampa London, England : , : Academic Press, , 2015
Descrizione fisica 1 online resource (423 p.)
Disciplina 572.696
Soggetto topico Biological transport - Regulation
Biological transport, Active
ISBN 0-12-416583-4
0-12-416579-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Channels, Carriers, and Pumps; Copyright Page; Dedications; Contents; Preface to the First Edition; Preface to the Second Edition; List of Symbols; 1 Structural Basis of Movement Across Cell Membranes; 1.1 Membrane Structure: Electron Microscopy of Biological Membranes; 1.2 Chemical Composition of Biological Membranes; 1.2.1 Membrane Lipids; 1.2.2 Membrane Proteins; 1.2.3 Membrane Carbohydrates; 1.3 Membrane Phospholipid Structures and Their Self-Assembly; 1.4 Phase Transitions in Biological Membranes; 1.5 Membrane Proteins: Their Structure and Arrangement
1.5.1 Proteins That Span the Membrane Only Once1.5.2 Proteins That Span the Membrane More Than Once; 1.6 Synthesis of Membrane Proteins; 1.7 Quantitation of Membrane Dynamics; 1.8 Traffic Across the Plasma Membrane; 1.9 The Cell Membrane as a Barrier and as a Passage; Suggested Readings; General; Membrane Structure; Membrane Lipids; Liposomes; Membrane Proteins; Membrane Dynamics; Glycophorin; Lactose Permease; Hydropathy Plots; Membrane Protein Structure; Synthesis of Membrane Proteins; Endocytosis, Membrane Turnover; Clathrin-Coated Pits and Caveolae; Lipid Rafts; Cytoskeleton
2 Simple Diffusion of Nonelectrolytes and Ions2.1 Diffusion as a Random Walk; 2.2 The Electrical Force Acting on an Ion; 2.3 Permeability Coefficients and Partition Coefficients; 2.4 Measurement of Permeability Coefficients; 2.5 Analysis of Permeability Data; 2.6 The Membrane as a Hydrophobic Sieve; 2.7 Osmosis and the Diffusion of Water; 2.8 Comparison of Osmotic and Diffusive Flow of Water; Suggested Readings; General; Diffusion as a Random Walk; Chemical Potential; Electrical Potential; Flux Ratio Test; Permeability and Partition Coefficients; Measurement of Permeability Coefficients
NMR and ESRUnstirred Layers; Plant Cell Permeabilities; Membrane as a Hydrophobic Sieve; Osmosis and the Diffusion of Water; Water Channels - The Aquaporins; Electroosmosis and Streaming Potential; 3 Ion Channels Across Cell Membranes; 3.1 The Gramicidin Channel; 3.2 The Acetylcholine Receptor Channel; 3.3 Conductances and Cross-Sectional Areas of Single Channels; 3.4 An Experimental Interlude; 3.4.1 Identification of Channels by Patch-Clamping; 3.4.2 Measurements of Membrane Potential by Using Intracellular Microelectrodes or by Following Dye Distribution
3.5 Diffusion Potentials: Goldman-Hodgkin-Katz Equation3.6 Regulation and Modulation of Channel Opening; 3.6.1 The Potassium Channel of Sarcoplasmic Reticulum; 3.6.2 Sodium and Potassium Channels of Excitable Tissue; 3.6.3 The Cell-to-Cell Channel or Gap Junction; 3.6.4 Regulation and Modulation of Some Other Channels; Suggested Readings; Internet Resources; General; Electrostatic (Born) Free Energy; Gramicidin Channel; Enzyme Kinetics; Acetylcholine Receptor; Cloning and Molecular Biology; Acetylcholine Receptor Structure; Ionic Diffusion; Ligand-gated Ion Channels
Charge Effects on Channel Conductance
Record Nr. UNINA-9910787112103321
Stein Wilfred D.  
London, England : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Channels, carriers, and pumps : an introduction to membrane transport / / Wilfred D. Stein, Thomas Litman
Channels, carriers, and pumps : an introduction to membrane transport / / Wilfred D. Stein, Thomas Litman
Autore Stein Wilfred D.
Edizione [Second edition.]
Pubbl/distr/stampa London, England : , : Academic Press, , 2015
Descrizione fisica 1 online resource (423 p.)
Disciplina 572.696
Soggetto topico Biological transport - Regulation
Biological transport, Active
ISBN 0-12-416583-4
0-12-416579-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Channels, Carriers, and Pumps; Copyright Page; Dedications; Contents; Preface to the First Edition; Preface to the Second Edition; List of Symbols; 1 Structural Basis of Movement Across Cell Membranes; 1.1 Membrane Structure: Electron Microscopy of Biological Membranes; 1.2 Chemical Composition of Biological Membranes; 1.2.1 Membrane Lipids; 1.2.2 Membrane Proteins; 1.2.3 Membrane Carbohydrates; 1.3 Membrane Phospholipid Structures and Their Self-Assembly; 1.4 Phase Transitions in Biological Membranes; 1.5 Membrane Proteins: Their Structure and Arrangement
1.5.1 Proteins That Span the Membrane Only Once1.5.2 Proteins That Span the Membrane More Than Once; 1.6 Synthesis of Membrane Proteins; 1.7 Quantitation of Membrane Dynamics; 1.8 Traffic Across the Plasma Membrane; 1.9 The Cell Membrane as a Barrier and as a Passage; Suggested Readings; General; Membrane Structure; Membrane Lipids; Liposomes; Membrane Proteins; Membrane Dynamics; Glycophorin; Lactose Permease; Hydropathy Plots; Membrane Protein Structure; Synthesis of Membrane Proteins; Endocytosis, Membrane Turnover; Clathrin-Coated Pits and Caveolae; Lipid Rafts; Cytoskeleton
2 Simple Diffusion of Nonelectrolytes and Ions2.1 Diffusion as a Random Walk; 2.2 The Electrical Force Acting on an Ion; 2.3 Permeability Coefficients and Partition Coefficients; 2.4 Measurement of Permeability Coefficients; 2.5 Analysis of Permeability Data; 2.6 The Membrane as a Hydrophobic Sieve; 2.7 Osmosis and the Diffusion of Water; 2.8 Comparison of Osmotic and Diffusive Flow of Water; Suggested Readings; General; Diffusion as a Random Walk; Chemical Potential; Electrical Potential; Flux Ratio Test; Permeability and Partition Coefficients; Measurement of Permeability Coefficients
NMR and ESRUnstirred Layers; Plant Cell Permeabilities; Membrane as a Hydrophobic Sieve; Osmosis and the Diffusion of Water; Water Channels - The Aquaporins; Electroosmosis and Streaming Potential; 3 Ion Channels Across Cell Membranes; 3.1 The Gramicidin Channel; 3.2 The Acetylcholine Receptor Channel; 3.3 Conductances and Cross-Sectional Areas of Single Channels; 3.4 An Experimental Interlude; 3.4.1 Identification of Channels by Patch-Clamping; 3.4.2 Measurements of Membrane Potential by Using Intracellular Microelectrodes or by Following Dye Distribution
3.5 Diffusion Potentials: Goldman-Hodgkin-Katz Equation3.6 Regulation and Modulation of Channel Opening; 3.6.1 The Potassium Channel of Sarcoplasmic Reticulum; 3.6.2 Sodium and Potassium Channels of Excitable Tissue; 3.6.3 The Cell-to-Cell Channel or Gap Junction; 3.6.4 Regulation and Modulation of Some Other Channels; Suggested Readings; Internet Resources; General; Electrostatic (Born) Free Energy; Gramicidin Channel; Enzyme Kinetics; Acetylcholine Receptor; Cloning and Molecular Biology; Acetylcholine Receptor Structure; Ionic Diffusion; Ligand-gated Ion Channels
Charge Effects on Channel Conductance
Record Nr. UNINA-9910824559203321
Stein Wilfred D.  
London, England : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Colloquium on molecular kinesis in cellular function and plasticity [[electronic resource] /] / [edited by Henri Tiedge, Floyd E. Bloom, and Dietmar Richter]
Colloquium on molecular kinesis in cellular function and plasticity [[electronic resource] /] / [edited by Henri Tiedge, Floyd E. Bloom, and Dietmar Richter]
Pubbl/distr/stampa Washington, D.C., : National Academy of Sciences, 2002
Descrizione fisica 1 online resource (116 p.)
Disciplina 571.6
Altri autori (Persone) TiedgeHenri
BloomFloyd E
RichterDietmar M
Collana National Academy of Sciences colloquium series
Soggetto topico Biological transport, Active
Proteins - Physiological transport
Cell membranes
Molecular biology
Soggetto genere / forma Electronic books.
ISBN 1-280-18474-4
9786610184743
0-309-57030-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Colloquium on Molecular Kinesis in Cellular Function and Plasticity""; ""National Academy of Sciences""; ""Contents""; ""Colloquium Molecular kinesis in cellular function and plasticity""; ""MOLECULAR MOTORS""; ""TRANSLATION INITIATION""; ""LOCALIZED RNAS""; ""NEURONAL PLASTICITY""; ""Colloquium Kinesin molecular motors: Transport pathways, receptors, and human disease""; ""LESSONS FROM GREEN ALGAE: POSSIBLE LINKS OF INTRAFLAGELLAR TRANSPORT TO HUMAN DISEASE""; ""LESSONS FROM FRUIT FLIES: ANTEROGRADE AXONAL TRANSPORT AND MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING""
""LESSONS FROM HUMANS: FROM ALZHEIMER�S DISEASE TO KINESIN-I RECEPTORS""""KINESIN RECEPTORS AND KINESIN REGULATION""; ""A SPECULATIVE PROPOSAL FOR THE RELATIONSHIP OF AXONAL TRANSPORT TO THE INITIATION OF ALZHEIMER�S DISEASE""; ""CONCLUDING REMARKS""; ""Colloquium All kinesin superfamily protein, KIF, genes in mouse and human""; ""MATERIALS AND METHODS""; ""RESULTS AND DISCUSSION""; ""Colloquium Assembly and transport of a premessenger RNP particle""; ""VISUALIZATION OF ASSEMBLY AND TRANSPORT OF BR PARTICLES""; ""APPROACH TO STUDY BR RNA-BINDING PROTEINS""
""SPLICEOSOME ASSEMBLY AND DISASSEMBLY""""PROTEINS CONFINED TO THE NUCLEUS""; ""PROTEINS ACCOMPANYING THE MRNA INTO THE CYTOPLASM""; ""THE COTRANSCRIPTIONAL LOADING STAGE""; ""CONCLUSIONS""; ""Colloquium Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome""; ""Colloquium Spatial and temporal control of RNA stability""; ""TEMPORAL CONTROL OF MATERNAL RNA STABILITY IN DROSOPHILA""; ""GENETIC CONTROL OF MATERNAL RNA STABILITY IN DROSOPHILA""; ""CONTROL OF RNA STABILITY IN A SOMATIC CELL LINEAGE""
""EVOLUTIONARY CONSERVATION OF DEGRADATION-PROTECTION MECHANISMS""""FUNCTIONS OF TRANSCRIPT DEGRADATION AND PROTECTION""; ""CONCLUSIONS""; ""Colloquium Molecular mechanisms of translation initiation in eukaryotes""; ""Colloquium The target of rapamycin (TOR) proteins ""; ""RAPAMYCIN INHIBITS LONG-TERM FACILITATION""; ""RAPAMYCIN AND TOR""; ""TOR SIGNALING""; ""TOR SIGNALING MODULATES THE PHOSPHORYLATION STATE OF PROTEINS INVOLVED IN TRANSLATIONAL CONTROL""; ""TOR REGULATES THE ABUNDANCE OF THE TRANSLATION MACHINERY""; ""TOR AS A MASTER SWITCH FOR CATABOLISM VS. ANABOLISM""
""HOW MIGHT TOR SIGNALING BE INVOLVED IN LEARNING AND MEMORY?""""TOR ACTIVITY IS REQUIRED FOR MURINE FOREBRAIN DEVELOPMENT""; ""SUMMARY AND FUTURE PROSPECTS""; ""Colloquium The physiological significance of B-actin mRNA localization in determining cell polarity and directional motility""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Colloquium Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture""; ""METHODS""; ""RESULTS""; ""DISCUSSION""; ""Colloquium Molecular organization of the postsynaptic specialization""
""THE NMDA RECEPTOR-PSD-95 COMPLEX""
Altri titoli varianti Molecular kinesis in cellular function and plasticity
Record Nr. UNINA-9910456460003321
Washington, D.C., : National Academy of Sciences, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Colloquium on molecular kinesis in cellular function and plasticity [[electronic resource] /] / [edited by Henri Tiedge, Floyd E. Bloom, and Dietmar Richter]
Colloquium on molecular kinesis in cellular function and plasticity [[electronic resource] /] / [edited by Henri Tiedge, Floyd E. Bloom, and Dietmar Richter]
Pubbl/distr/stampa Washington, D.C., : National Academy of Sciences, 2002
Descrizione fisica 1 online resource (116 p.)
Disciplina 571.6
Altri autori (Persone) TiedgeHenri
BloomFloyd E
RichterDietmar M
Collana National Academy of Sciences colloquium series
Soggetto topico Biological transport, Active
Proteins - Physiological transport
Cell membranes
Molecular biology
ISBN 1-280-18474-4
9786610184743
0-309-57030-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Colloquium on Molecular Kinesis in Cellular Function and Plasticity""; ""National Academy of Sciences""; ""Contents""; ""Colloquium Molecular kinesis in cellular function and plasticity""; ""MOLECULAR MOTORS""; ""TRANSLATION INITIATION""; ""LOCALIZED RNAS""; ""NEURONAL PLASTICITY""; ""Colloquium Kinesin molecular motors: Transport pathways, receptors, and human disease""; ""LESSONS FROM GREEN ALGAE: POSSIBLE LINKS OF INTRAFLAGELLAR TRANSPORT TO HUMAN DISEASE""; ""LESSONS FROM FRUIT FLIES: ANTEROGRADE AXONAL TRANSPORT AND MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING""
""LESSONS FROM HUMANS: FROM ALZHEIMER�S DISEASE TO KINESIN-I RECEPTORS""""KINESIN RECEPTORS AND KINESIN REGULATION""; ""A SPECULATIVE PROPOSAL FOR THE RELATIONSHIP OF AXONAL TRANSPORT TO THE INITIATION OF ALZHEIMER�S DISEASE""; ""CONCLUDING REMARKS""; ""Colloquium All kinesin superfamily protein, KIF, genes in mouse and human""; ""MATERIALS AND METHODS""; ""RESULTS AND DISCUSSION""; ""Colloquium Assembly and transport of a premessenger RNP particle""; ""VISUALIZATION OF ASSEMBLY AND TRANSPORT OF BR PARTICLES""; ""APPROACH TO STUDY BR RNA-BINDING PROTEINS""
""SPLICEOSOME ASSEMBLY AND DISASSEMBLY""""PROTEINS CONFINED TO THE NUCLEUS""; ""PROTEINS ACCOMPANYING THE MRNA INTO THE CYTOPLASM""; ""THE COTRANSCRIPTIONAL LOADING STAGE""; ""CONCLUSIONS""; ""Colloquium Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome""; ""Colloquium Spatial and temporal control of RNA stability""; ""TEMPORAL CONTROL OF MATERNAL RNA STABILITY IN DROSOPHILA""; ""GENETIC CONTROL OF MATERNAL RNA STABILITY IN DROSOPHILA""; ""CONTROL OF RNA STABILITY IN A SOMATIC CELL LINEAGE""
""EVOLUTIONARY CONSERVATION OF DEGRADATION-PROTECTION MECHANISMS""""FUNCTIONS OF TRANSCRIPT DEGRADATION AND PROTECTION""; ""CONCLUSIONS""; ""Colloquium Molecular mechanisms of translation initiation in eukaryotes""; ""Colloquium The target of rapamycin (TOR) proteins ""; ""RAPAMYCIN INHIBITS LONG-TERM FACILITATION""; ""RAPAMYCIN AND TOR""; ""TOR SIGNALING""; ""TOR SIGNALING MODULATES THE PHOSPHORYLATION STATE OF PROTEINS INVOLVED IN TRANSLATIONAL CONTROL""; ""TOR REGULATES THE ABUNDANCE OF THE TRANSLATION MACHINERY""; ""TOR AS A MASTER SWITCH FOR CATABOLISM VS. ANABOLISM""
""HOW MIGHT TOR SIGNALING BE INVOLVED IN LEARNING AND MEMORY?""""TOR ACTIVITY IS REQUIRED FOR MURINE FOREBRAIN DEVELOPMENT""; ""SUMMARY AND FUTURE PROSPECTS""; ""Colloquium The physiological significance of B-actin mRNA localization in determining cell polarity and directional motility""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Colloquium Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture""; ""METHODS""; ""RESULTS""; ""DISCUSSION""; ""Colloquium Molecular organization of the postsynaptic specialization""
""THE NMDA RECEPTOR-PSD-95 COMPLEX""
Altri titoli varianti Molecular kinesis in cellular function and plasticity
Record Nr. UNINA-9910780006503321
Washington, D.C., : National Academy of Sciences, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Controlled nanoscale motion : Nobel Symposium 131 / / Heiner Linke, Alf Månsson, editors
Controlled nanoscale motion : Nobel Symposium 131 / / Heiner Linke, Alf Månsson, editors
Edizione [1st ed. 2007.]
Pubbl/distr/stampa Berlin, Germany ; ; New York, New York : , : Springer, , [2007]
Descrizione fisica 1 online resource (420 p.)
Disciplina 571.4
Collana Lecture Notes in Physics
Soggetto topico Biological transport, Active - Regulation
Biological transport, Active
Ultrastructure (Biology)
Nanotechnology
ISBN 1-280-85227-5
9786610852277
3-540-49522-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Navigation on a Micron Scale -- Myosin Motors: The Chemical Restraints Imposed by ATP -- How Linear Motor Proteins Work -- Axonal Transport: Imaging and Modeling of a Neuronal Process -- Intracellular Transport and Kinesin Superfamily Proteins: Structure, Function and Dynamics -- Studies of DNA-Protein Interactions at the Single Molecule Level with Magnetic Tweezers -- Membrane Nanotubes -- Macromolecular Motion at the Nanoscale of Enzymes Working on Polysaccharides -- Brownian Motion after Einstein: Some New Applications and New Experiments -- Nonequilibrium Fluctuations of a Single Biomolecule -- When is a Distribution Not a Distribution, and Why Would You Care: Single-Molecule Measurements of Repressor Protein 1-D Diffusion on DNA -- BioNEMS: Nanomechanical Systems for Single-Molecule Biophysics -- Nanodevices for Single Molecule Studies -- Artificial Dipolar Molecular Rotors -- Using DNA to Power the Nanoworld -- Tuning Ion Current Rectification in Synthetic Nanotubes -- NanoShuttles: Harnessing Motor Proteins to Transport Cargo in Synthetic Environments -- Nanotechnology Enhanced Functional Assays of Actomyosin Motility – Potentials and Challenges.
Record Nr. UNINA-9910146626903321
Berlin, Germany ; ; New York, New York : , : Springer, , [2007]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Controlled nanoscale motion : Nobel Symposium 131 / / Heiner Linke, Alf Månsson, editors
Controlled nanoscale motion : Nobel Symposium 131 / / Heiner Linke, Alf Månsson, editors
Edizione [1st ed. 2007.]
Pubbl/distr/stampa Berlin, Germany ; ; New York, New York : , : Springer, , [2007]
Descrizione fisica 1 online resource (420 p.)
Disciplina 571.4
Collana Lecture Notes in Physics
Soggetto topico Biological transport, Active - Regulation
Biological transport, Active
Ultrastructure (Biology)
Nanotechnology
ISBN 1-280-85227-5
9786610852277
3-540-49522-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Navigation on a Micron Scale -- Myosin Motors: The Chemical Restraints Imposed by ATP -- How Linear Motor Proteins Work -- Axonal Transport: Imaging and Modeling of a Neuronal Process -- Intracellular Transport and Kinesin Superfamily Proteins: Structure, Function and Dynamics -- Studies of DNA-Protein Interactions at the Single Molecule Level with Magnetic Tweezers -- Membrane Nanotubes -- Macromolecular Motion at the Nanoscale of Enzymes Working on Polysaccharides -- Brownian Motion after Einstein: Some New Applications and New Experiments -- Nonequilibrium Fluctuations of a Single Biomolecule -- When is a Distribution Not a Distribution, and Why Would You Care: Single-Molecule Measurements of Repressor Protein 1-D Diffusion on DNA -- BioNEMS: Nanomechanical Systems for Single-Molecule Biophysics -- Nanodevices for Single Molecule Studies -- Artificial Dipolar Molecular Rotors -- Using DNA to Power the Nanoworld -- Tuning Ion Current Rectification in Synthetic Nanotubes -- NanoShuttles: Harnessing Motor Proteins to Transport Cargo in Synthetic Environments -- Nanotechnology Enhanced Functional Assays of Actomyosin Motility – Potentials and Challenges.
Record Nr. UNISA-996466706603316
Berlin, Germany ; ; New York, New York : , : Springer, , [2007]
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Expression and analysis of recombinant ion channels [[electronic resource] ] : from structural studies to pharmacological screening / / edited by Jeffrey J. Clare, Derek J. Trezise
Expression and analysis of recombinant ion channels [[electronic resource] ] : from structural studies to pharmacological screening / / edited by Jeffrey J. Clare, Derek J. Trezise
Pubbl/distr/stampa Weinheim ; ; [Chichester], : Wiley-VCH, c2006
Descrizione fisica 1 online resource (305 p.)
Disciplina 572.3
Altri autori (Persone) ClareJeffrey J
TreziseDerek J
Soggetto topico Ion channels
Biological transport, Active
Soggetto genere / forma Electronic books.
ISBN 1-280-72342-4
9786610723423
3-527-60809-5
3-527-60793-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Expression and Analysis of Recombinant Ion Channels; Contents; Preface; List of Contributors; Color Plates; 1 Expression of Ion Channels in Xenopus Oocytes; 1.1 Introduction; 1.2 Advantages and Disadvantages of Xenopus Oocytes; 1.3 Procedures for Using Oocytes; 1.4 Types of Analyses; 1.4.1 Electrophysiological Analysis; 1.4.1.1 Two-electrode Whole Cell Voltage-clamp; 1.4.1.2 Cut-open Oocyte Voltage-clamp; 1.4.1.3 Macropatch Clamp; 1.4.1.4 Single Channel Analysis; 1.4.2 Biochemical Analysis; 1.4.3 Compound Screening; 1.4.3.1 Serial Recording Using the Roboocyte
1.4.3.2 Parallel Recording Using the OpusXpress1.5 Examples of Use; 1.5.1 Characterization of cDNA Clones for a Channel; 1.5.2 Structure-Function Correlations; 1.5.3 Studies of Human Disease Mutations; 1.6 Conclusions; Acknowledgments; References; 2 Molecular Biology Techniques for Structure - Function Studies of Ion Channels; 2.1 Introduction; 2.2 Methods for cDNA Subcloning; 2.2.1 Conventional Sub-cloning Using Restriction Enzymes and DNA Ligase; 2.2.2 PCR-based cDNA Sub-cloning; 2.2.3 Sub-cloning cDNA through Site-specific Recombination; 2.3 Generation of Chimeric Channel cDNAs
2.3.1 Use of Restriction Enzymes to Generate Chimeric Channel cDNAs2.3.2 PCR-mediated Overlap Extension for Chimera Generation; 2.3.3 PCR-mediated Integration or Replacement of cDNA Fragments; 2.4 Site-directed Mutagenesis; 2.4.1 Examples of the Use of Site-directed Mutagenesis; 2.4.2 Modification of the QuikChange Method for the Replacement of cDNA Fragments; 2.5 Epitope-tagged Channels and Fusion Partners; 2.6 Channel Subunit Concatamers; 2.7 Concluding Remarks; References; 3 Unnatural Amino Acids as Probes of Ion Channel Structure - Function and Pharmacology; 3.1 Introduction
3.2 Unnatural Amino Acid Mutagenesis Methodology3.3 Unnatural Amino Acid Mutagenesis for Ion Channel Studies; 3.4 Structure-Function Example Studies; 3.4.1 Nicotinic Acetylcholine Receptor; 3.4.2 Drug Interactions with the hERG Voltage-gated Potassium Ion Channel; 3.5 Other Uses of Unnatural Amino Acids as Probes of Protein Structure and Function; 3.6 Conclusions; Acknowledgements; References; 4 Functional Expression of Ion Channels in Mammalian Systems; 4.1 Introduction; 4.2 cDNA Cloning and Manipulation; 4.3 Choice of Host Cell Background
4.4 Post-translational Processing of Heterologous Expressed Ion Channels4.5 Cytotoxicity; 4.6 Transient Expression Systems; 4.6.1 "Standard" Transient Expression; 4.6.2 Viral Expression Systems; 4.7 Stable Expression of Ion Channels; 4.7.1 Bicistronic Expression Systems; 4.7.2 Stable Expression of Multiple Subunits; 4.7.3 Inducible Expression; 4.8 Summary; Acknowledgements; References; 5 Analysis of Electrophysiological Data; 5.1 Overview; 5.2 Introduction; 5.3 Expression Systems and Related Recording Techniques; 5.3.1 Expression in Xenopus Oocytes; 5.3.2 Expression in Mammalian Cells
5.3.3 Leak and Capacitance Subtraction
Record Nr. UNINA-9910143961803321
Weinheim ; ; [Chichester], : Wiley-VCH, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui