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Carbohydrate binding modules [[electronic resource] ] : functions and applications / / Susana Moreira and Miguel Gama, editors
| Carbohydrate binding modules [[electronic resource] ] : functions and applications / / Susana Moreira and Miguel Gama, editors |
| Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publisher's, c2009 |
| Descrizione fisica | 1 online resource (78 p.) |
| Disciplina | 612.3/96 |
| Altri autori (Persone) |
MoreiraSusana
GamaMiguel |
| Collana | Biotechnology in agriculture, industry and medicine series |
| Soggetto topico |
Carbohydrates
Enzymes Binding sites (Biochemistry) |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61209-869-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910465186803321 |
| Hauppauge, NY, : Nova Science Publisher's, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Carbohydrate binding modules [[electronic resource] ] : functions and applications / / Susana Moreira and Miguel Gama, editors
| Carbohydrate binding modules [[electronic resource] ] : functions and applications / / Susana Moreira and Miguel Gama, editors |
| Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publisher's, c2009 |
| Descrizione fisica | 1 online resource (78 p.) |
| Disciplina | 612.3/96 |
| Altri autori (Persone) |
MoreiraSusana
GamaMiguel |
| Collana | Biotechnology in agriculture, industry and medicine series |
| Soggetto topico |
Carbohydrates
Enzymes Binding sites (Biochemistry) |
| ISBN | 1-61209-869-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910791818203321 |
| Hauppauge, NY, : Nova Science Publisher's, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Carbohydrate binding modules : functions and applications / / Susana Moreira and Miguel Gama, editors
| Carbohydrate binding modules : functions and applications / / Susana Moreira and Miguel Gama, editors |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publisher's, c2009 |
| Descrizione fisica | 1 online resource (78 p.) |
| Disciplina | 612.3/96 |
| Altri autori (Persone) |
MoreiraSusana
GamaMiguel |
| Collana | Biotechnology in agriculture, industry and medicine series |
| Soggetto topico |
Carbohydrates
Enzymes Binding sites (Biochemistry) |
| ISBN | 1-61209-869-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Intro -- CARBOHYDRATE BINDING MODULES: FUNCTIONS AND APPLICATIONS -- CARBOHYDRATE BINDING MODULES: FUNCTIONS AND APPLICATIONS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTION -- Chapter 2 THE CBM STORY -- Chapter 3 CBM CLASSIFICATION -- 3.1. CBM FAMILIES -- 3.1.1. Cellulosomes -- 3.2. CBM TYPES -- 3.2.1. Type A CBMs -- 3.2.2. Type B CBMs -- 3.2.3. Type C CBMs -- Chapter 4 CBMS AT WORK -- 4.1. THE PROXIMITY EFFECT -- 4.2. THE TARGETING EFFECT -- 4.3. THE DISRUPTIVE EFFECT -- 4.4. THE AVIDITY EFFECT -- Chapter 5 CBMS AND PHYSIOLOGIC FUNCTION -- 5.1. CBMS IN PROTEIN TURNOVER -- 5. 2. CBMS IN ENERGY BALANCE AND DISEASES -- 5.3. CBMS ROLES IN PLANT: GROWTH, DEFENSE AND DEGRADATION -- 5.3.1 CBMs Acting on Polysaccharides: Cellulose, Starch, Chitin -- 5.3.2. CBMs in Biomass Conversion -- 5. 4. PLANT DEVELOPMENT -- 5. 5. PLANT DEFENSE -- Chapter 6 CBMS APPLICATIONS -- 6.1. CBMS IN THE PAPER INDUSTRY -- 6.2. CBMS IN THE TEXTILE INDUSTRY -- 6.3. CBMS IN THE FOOD INDUSTRY -- 6.4. CBMS AS A MICROARRAY AND PROBING TOOL -- 6.5. CBMS AS A PROTEIN SOLUBILIZATION, PURIFICATION AND IMMOBILIZATION TOOL -- 6.6. CBMS AS BIOREMEDIATION TOOL -- 6.7. CBMS AS BIOMEDICAL TOOL -- Chapter 7 FUTURE PERSPECTIVES -- REFERENCES -- INDEX. |
| Record Nr. | UNINA-9910819269603321 |
| Hauppauge, NY, : Nova Science Publisher's, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular and cellular mechanisms of antibody activity / / Falk Nimmerjahn, editor
| Molecular and cellular mechanisms of antibody activity / / Falk Nimmerjahn, editor |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, : Springer, 2013 |
| Descrizione fisica | 1 online resource (300 p.) |
| Disciplina | 616.0798 |
| Altri autori (Persone) | NimmerjahnFalk |
| Soggetto topico |
Antigen-antibody reactions
Immunospecificity Binding sites (Biochemistry) |
| ISBN | 1-4614-7107-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | IgM and IgD in infection and inflammatory diseases -- Immunoglobulin A – molecular mechanisms of function and role in immune defense -- Crystal structures of human IgG Fc-fragments and their complexes with Fc Receptors -- The role of IgG in immune responses -- Molecular and cellular pathways involved in the anti-inflammatory activity of IgG -- Example of the Pathogenic Potential of Two Sets of Autoantibodies: Anti-RBC and IgG3 RF Cryoglobulins -- Cross-talk between antibodies, IgG Fc receptors and the complement system -- Regulation of immunological responses by the neonatal Fc receptor for IgG, FcRn -- Antibody mediated regulation of humoral immunity -- Engineered antibody derivatives in preclinical and clinical development. |
| Record Nr. | UNINA-9910437843403321 |
| New York, : Springer, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Receptor biology / / Michael F. Roberts and Anne E. Kruhchten
| Receptor biology / / Michael F. Roberts and Anne E. Kruhchten |
| Autore | Roberts Michael F. |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] |
| Descrizione fisica | 1 online resource (478 p.) |
| Soggetto topico |
Cell receptors
Nuclear receptors (Biochemistry) Binding sites (Biochemistry) Ligands (Biochemistry) |
| Soggetto genere / forma | Electronic books. |
| ISBN | 3-527-80015-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title Page; Copyright; Dedication; Table of Contents; Acknowledgments; Part I: Introduction; Chapter 1: Introduction; 1.1 Receptors and Signaling; 1.2 Types of Receptors and Hormones; 1.3 Receptors Are the Chemical Expression of Reality; Chapter 2: The Origins of Chemical Thinking; 2.1 Overview of Early Pharmacological History; 2.2 Modern Pharmacology; 2.3 Phylogenetics of Signaling; Part II: Fundamentals; Chapter 3: Membranes and Proteins; 3.1 Membranes; 3.2 The Nature and Function of Proteins; Chapter 4: Hormones as First Messengers; 4.1 Hormones and Cellular Communication
4.2 Types of Hormones4.3 Vertebrate Hormones and Transmitters; 4.4 Analgesics and Venoms as Receptor Ligands; Chapter 5: Receptor Theory; 5.1 The Materialization of Receptors; 5.2 Receptor Mechanisms; 5.3 Binding Theory; 5.4 Visualizing Receptor Structure and Function; 5.5 Proteomics Approaches to Receptor Efficacy; 5.6 Physical Factors Affecting Receptor Binding; Part III: Receptor Types and Function; Chapter 6: Transduction I: Ion Channels and Transporters; 6.1 Introduction; 6.2 Small Molecule Channels; 6.3 Transporters; 6.4 Major Intrinsic Proteins; 6.5 Ligand-Gated Ion Channels Chapter 7: Transduction II: G-Protein-Coupled Receptors7.1 Introduction; 7.2 Families of G-Protein-Coupled Receptors; 7.3 Transduction Mechanisms; 7.4 The Major Families of G Protein-Coupled Receptors; Chapter 8: Transduction III: Receptor Kinases and Immunoglobulins; 8.1 Protein Kinases; 8.2 Receptors for Cell Division and Metabolism; 8.3 Receptor Serine/Threonine Kinases; 8.4 The Guanylyl Cyclase Receptor Subfamily - Natriuretic Peptide Receptors; 8.5 Non-Kinase Molecules - LDL Receptors; 8.6 Cell-Cell Contact Signaling; 8.7 Immune System Receptors, Antibodies, and Cytokines Chapter 9: Transduction IV: Nuclear Receptors9.1 Introduction; 9.2 Genomic Actions of Nuclear Receptors; 9.3 Actions of Receptor Antagonists; 9.4 Non-Traditional Actions of Steroid-Like Hormones and Their Receptors; Part IV: Applications; Chapter 10: Signaling Complexity; 10.1 Introduction; 10.2 Experimental Determination of Signaling Cascades; 10.3 Transduction across the Membrane; 10.4 Complexity in Cross Talk - Roles of PIP3, Akt, and PDK1; 10.5 Role in Cancer; 10.6 Signaling Mediated by Gas Molecules; Chapter 11: Cellular Interactions in Development; 11.1 Introduction 11.2 The Origins of Multicellularity11.3 The Origin of Symmetry and Axes; 11.4 Fertilization and Organization of the Multicellular Body Plan; 11.5 Differentiation of Triploblastic Embryos - Organogenesis; 11.6 Programmed Cell Death (Apoptosis); Chapter 12: Receptor Mechanisms in Disease Processes; 12.1 Genetic Basis for Receptor Function; 12.2 Receptor Pathologies; 12.3 Signaling Mutations Leading to Cancer; Chapter 13: Receptors and the Mind; 13.1 Origins of Behavior; 13.2 Nervous Systems; 13.3 Animal Memory: Invertebrates; 13.4 Animal Memory: Vertebrates 13.5 Receptors and Behavior: Addiction, Tolerance, and Dependence |
| Record Nr. | UNINA-9910466108203321 |
Roberts Michael F.
|
||
| Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Receptor biology / / Michael F. Roberts and Anne E. Kruhchten
| Receptor biology / / Michael F. Roberts and Anne E. Kruhchten |
| Autore | Roberts Michael F. |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] |
| Descrizione fisica | 1 online resource (478 pages) : illustrations (some color) |
| Soggetto topico |
Binding sites (Biochemistry)
Cell receptors Ligands (Biochemistry) Nuclear receptors (Biochemistry) |
| ISBN |
3-527-80017-4
3-527-80015-8 |
| Classificazione |
463.6
571.6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910796090903321 |
|
Roberts Michael F.
|
||
| Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Receptor biology / / Michael F. Roberts and Anne E. Kruhchten
| Receptor biology / / Michael F. Roberts and Anne E. Kruhchten |
| Autore | Roberts Michael F. |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] |
| Descrizione fisica | 1 online resource (478 pages) : illustrations (some color) |
| Soggetto topico |
Binding sites (Biochemistry)
Cell receptors Ligands (Biochemistry) Nuclear receptors (Biochemistry) |
| ISBN |
3-527-80017-4
3-527-80015-8 |
| Classificazione |
463.6
571.6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910822760103321 |
|
Roberts Michael F.
|
||
| Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Small molecule DNA and RNA binders [[electronic resource] ] : from synthesis to nucleic acid complexes / / M. Demeunynck, C. Bailly, W. D. Wilson (eds.)
| Small molecule DNA and RNA binders [[electronic resource] ] : from synthesis to nucleic acid complexes / / M. Demeunynck, C. Bailly, W. D. Wilson (eds.) |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2003 |
| Descrizione fisica | 1 online resource (756 p.) |
| Disciplina | 572.8 |
| Altri autori (Persone) |
DemeunynckM (Martine)
BaillyChristian WilsonW. D (W. David) |
| Soggetto topico |
DNA-drug interactions
Molecular biology Binding sites (Biochemistry) Nucleic acids |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-52066-3
9786610520664 3-527-60566-5 3-527-60178-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Small Molecule DNA and RNA Binders; Contents; Preface; Contributors; 1 Forty Years On; 1.1 Early Experiments Prior to Molecular Modeling; 1.2 Formulation of Molecular Models and Mechanisms of Binding to DNA; 1.3 Specificity of Nucleotide Sequence Recognition; 1.4 Details at the Atomic and Molecular Levels; 1.5 Identification of Motifs for Drug Design; 1.6 Actions on Nucleoproteins, Chromatin, and Enzymes; References; 2 Targeting HIV RNA with Small Molecules; 2.1 Introduction; 2.1.1 Translation; 2.1.2 RNA Viruses; 2.2 Small Molecules that Modulate RNA Activity; 2.2.1 Magnesium (II)
2.2.2 Aminoglycosides2.2.3 Ligand Specificity; 2.2.4 Goals; 2.3 The RRE and HIV Replication; 2.4 Determination of RRE-Ligand Affinity and Specificity; 2.4.1 Fluorescence Anisotropy; 2.4.2 Solid-phase (Affinity-Displacement) Assay; 2.4.3 Ethidium Bromide Displacement; 2.5 New RRE Ligands; 2.5.1 Neomycin-Acridine Conjugates; 2.5.2 Dimeric Aminoglycosides; 2.5.3 Guanidinoglycosides; 2.6 Conclusions; Acknowledgments; References; 3 RNA Targeting by Bleomycin; 3.1 Activation of Bleomycin for Polynucleotide Degradation; 3.2 Bleomycin-mediated Cleavage of Transfer RNAs and tRNA Precursor Transcripts 4.6 Combinatorial Library Approach in the Discovery of Small Molecule Drugs Targeting RNA4.6.1 Combinatorial Chemistry; 4.6.2 Split Synthesis; 4.6.3 Encoding; 4.6.4 On-bead Screening and Identification of Structure-specific TAR-Binding Ligands; 4.6.5 Ligand Sequence Analysis; 4.6.6 Heterochiral Small Molecules Target TAR RNA Bulge; 4.6.7 Inhibition of Tat trans-Activation in vivo; 4.7 Cyclic Structures as RNA-targeting Drugs; 4.8 Summary and Perspective; Acknowledgments; References; 5 DNA and RNA Recognition and Modification by Gly-Gly-His-Derived Metallopeptides; 5.1 Introduction 5.2.3.5 Guanine nucleobase modification/oxidation |
| Record Nr. | UNINA-9910146239303321 |
| Weinheim, : Wiley-VCH, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Small molecule DNA and RNA binders [[electronic resource] ] : from synthesis to nucleic acid complexes / / M. Demeunynck, C. Bailly, W. D. Wilson (eds.)
| Small molecule DNA and RNA binders [[electronic resource] ] : from synthesis to nucleic acid complexes / / M. Demeunynck, C. Bailly, W. D. Wilson (eds.) |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2003 |
| Descrizione fisica | 1 online resource (756 p.) |
| Disciplina | 572.8 |
| Altri autori (Persone) |
DemeunynckM (Martine)
BaillyChristian WilsonW. D (W. David) |
| Soggetto topico |
DNA-drug interactions
Molecular biology Binding sites (Biochemistry) Nucleic acids |
| ISBN |
1-280-52066-3
9786610520664 3-527-60566-5 3-527-60178-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Small Molecule DNA and RNA Binders; Contents; Preface; Contributors; 1 Forty Years On; 1.1 Early Experiments Prior to Molecular Modeling; 1.2 Formulation of Molecular Models and Mechanisms of Binding to DNA; 1.3 Specificity of Nucleotide Sequence Recognition; 1.4 Details at the Atomic and Molecular Levels; 1.5 Identification of Motifs for Drug Design; 1.6 Actions on Nucleoproteins, Chromatin, and Enzymes; References; 2 Targeting HIV RNA with Small Molecules; 2.1 Introduction; 2.1.1 Translation; 2.1.2 RNA Viruses; 2.2 Small Molecules that Modulate RNA Activity; 2.2.1 Magnesium (II)
2.2.2 Aminoglycosides2.2.3 Ligand Specificity; 2.2.4 Goals; 2.3 The RRE and HIV Replication; 2.4 Determination of RRE-Ligand Affinity and Specificity; 2.4.1 Fluorescence Anisotropy; 2.4.2 Solid-phase (Affinity-Displacement) Assay; 2.4.3 Ethidium Bromide Displacement; 2.5 New RRE Ligands; 2.5.1 Neomycin-Acridine Conjugates; 2.5.2 Dimeric Aminoglycosides; 2.5.3 Guanidinoglycosides; 2.6 Conclusions; Acknowledgments; References; 3 RNA Targeting by Bleomycin; 3.1 Activation of Bleomycin for Polynucleotide Degradation; 3.2 Bleomycin-mediated Cleavage of Transfer RNAs and tRNA Precursor Transcripts 4.6 Combinatorial Library Approach in the Discovery of Small Molecule Drugs Targeting RNA4.6.1 Combinatorial Chemistry; 4.6.2 Split Synthesis; 4.6.3 Encoding; 4.6.4 On-bead Screening and Identification of Structure-specific TAR-Binding Ligands; 4.6.5 Ligand Sequence Analysis; 4.6.6 Heterochiral Small Molecules Target TAR RNA Bulge; 4.6.7 Inhibition of Tat trans-Activation in vivo; 4.7 Cyclic Structures as RNA-targeting Drugs; 4.8 Summary and Perspective; Acknowledgments; References; 5 DNA and RNA Recognition and Modification by Gly-Gly-His-Derived Metallopeptides; 5.1 Introduction 5.2.3.5 Guanine nucleobase modification/oxidation |
| Record Nr. | UNINA-9910831076803321 |
| Weinheim, : Wiley-VCH, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Small molecule DNA and RNA binders : from synthesis to nucleic acid complexes / / M. Demeunynck, C. Bailly, W. D. Wilson (eds.)
| Small molecule DNA and RNA binders : from synthesis to nucleic acid complexes / / M. Demeunynck, C. Bailly, W. D. Wilson (eds.) |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2003 |
| Descrizione fisica | 1 online resource (756 p.) |
| Disciplina | 572.8 |
| Altri autori (Persone) |
DemeunynckM (Martine)
BaillyChristian WilsonW. D (W. David) |
| Soggetto topico |
DNA-drug interactions
Molecular biology Binding sites (Biochemistry) Nucleic acids |
| ISBN |
1-280-52066-3
9786610520664 3-527-60566-5 3-527-60178-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Small Molecule DNA and RNA Binders; Contents; Preface; Contributors; 1 Forty Years On; 1.1 Early Experiments Prior to Molecular Modeling; 1.2 Formulation of Molecular Models and Mechanisms of Binding to DNA; 1.3 Specificity of Nucleotide Sequence Recognition; 1.4 Details at the Atomic and Molecular Levels; 1.5 Identification of Motifs for Drug Design; 1.6 Actions on Nucleoproteins, Chromatin, and Enzymes; References; 2 Targeting HIV RNA with Small Molecules; 2.1 Introduction; 2.1.1 Translation; 2.1.2 RNA Viruses; 2.2 Small Molecules that Modulate RNA Activity; 2.2.1 Magnesium (II)
2.2.2 Aminoglycosides2.2.3 Ligand Specificity; 2.2.4 Goals; 2.3 The RRE and HIV Replication; 2.4 Determination of RRE-Ligand Affinity and Specificity; 2.4.1 Fluorescence Anisotropy; 2.4.2 Solid-phase (Affinity-Displacement) Assay; 2.4.3 Ethidium Bromide Displacement; 2.5 New RRE Ligands; 2.5.1 Neomycin-Acridine Conjugates; 2.5.2 Dimeric Aminoglycosides; 2.5.3 Guanidinoglycosides; 2.6 Conclusions; Acknowledgments; References; 3 RNA Targeting by Bleomycin; 3.1 Activation of Bleomycin for Polynucleotide Degradation; 3.2 Bleomycin-mediated Cleavage of Transfer RNAs and tRNA Precursor Transcripts 4.6 Combinatorial Library Approach in the Discovery of Small Molecule Drugs Targeting RNA4.6.1 Combinatorial Chemistry; 4.6.2 Split Synthesis; 4.6.3 Encoding; 4.6.4 On-bead Screening and Identification of Structure-specific TAR-Binding Ligands; 4.6.5 Ligand Sequence Analysis; 4.6.6 Heterochiral Small Molecules Target TAR RNA Bulge; 4.6.7 Inhibition of Tat trans-Activation in vivo; 4.7 Cyclic Structures as RNA-targeting Drugs; 4.8 Summary and Perspective; Acknowledgments; References; 5 DNA and RNA Recognition and Modification by Gly-Gly-His-Derived Metallopeptides; 5.1 Introduction 5.2.3.5 Guanine nucleobase modification/oxidation |
| Altri titoli varianti | DNA and RNA binders : from small molecules to drugs |
| Record Nr. | UNINA-9910877717103321 |
| Weinheim, : Wiley-VCH, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Binding sites (Biochemistry)
(10)
- Carbohydrates (3)
- Cell receptors (3)
- DNA-drug interactions (3)
- Enzymes (3)