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Autophagy
Autophagy
Pubbl/distr/stampa [Georgetown, TX] : , : Landes Bioscience, , [2005]-
Descrizione fisica 1 online resource
Disciplina 571.9
Soggetto topico Cell death
Apoptosis
Homeostasis
Autophagic vacuoles
Lysosomes
Autophagy
Cell Death
Autofagie
Autofàgia
Soggetto genere / forma Periodical
Periodicals.
Revistes electròniques.
ISSN 1554-8635
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996218148803316
[Georgetown, TX] : , : Landes Bioscience, , [2005]-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Autophagy
Autophagy
Pubbl/distr/stampa [Georgetown, TX] : , : Landes Bioscience, , [2005]-
Descrizione fisica 1 online resource
Disciplina 571.9
Soggetto topico Cell death
Apoptosis
Homeostasis
Autophagic vacuoles
Lysosomes
Autophagy
Cell Death
Autofagie
Autofàgia
Soggetto genere / forma Periodical
Periodicals.
Revistes electròniques.
ISSN 1554-8635
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910145030203321
[Georgetown, TX] : , : Landes Bioscience, , [2005]-
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Autophagy in Stem Cell Maintenance and Differentiation / / edited by Bhupendra V. Shravage, Kursad Turksen
Autophagy in Stem Cell Maintenance and Differentiation / / edited by Bhupendra V. Shravage, Kursad Turksen
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (290 pages)
Disciplina 050
616.02774
Collana Stem Cell Biology and Regenerative Medicine
Soggetto topico Cancer
Stem cells
Cytology
Developmental biology
Cancer Stem Cells
Cell Biology
Developmental Biology and Stem Cells
Medicina regenerativa
Autofàgia
Cèl·lules mare
Soggetto genere / forma Llibres electrònics
ISBN 3-031-17362-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Assays for monitoring autophagy in stem cells -- Autophagy in Stem Cell Maintenance and Differentiation -- Autophagy in Embryonic stem cells and Neural stem cells -- Autophagy in Germline Stem Cells -- The role of autophagy in the regulation of hematopoietic stem cells -- Autophagy in Muscle Stem Cells -- Autophagy in Intestinal Stem Cells -- The autophagy lysosomal pathway: friend or foe in adult neural stem cells? -- Autophagy in Mesenchymal Stem Cell-based therapy -- Autophagic control of stem cells differentiation into osteogenic lineage- Implications in bone disorders -- Autophagy in Cancer Metastasis.
Record Nr. UNINA-9910629289703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Autophagy: Biology and Diseases : Technology and Methodology / / edited by Zhiping Xie
Autophagy: Biology and Diseases : Technology and Methodology / / edited by Zhiping Xie
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2021
Descrizione fisica 1 online resource (458 pages)
Disciplina 571.936
Collana Advances in Experimental Medicine and Biology
Soggetto topico Biotechnology
Medicine - Research
Biology - Research
Biology - Technique
Biomedical Research
Experimental Organisms
Autofàgia
Soggetto genere / forma Llibres electrònics
ISBN 981-16-2830-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Morphology Study – Optical Microscopy Imaging, Electron Microscopy Imaging, Confocal Microscopy Imaging, Live Cell Imaging -- Methods to Detect Autophagic Flux -- Biomarkers in Autophagy -- Drugs and Molecular Biology Technology in Autophagy Study -- Animal Models in Autophagy Study.
Record Nr. UNINA-9910492146303321
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2021
Materiale a stampa
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Autophagy: Biology and Diseases : Clinical Science / / edited by Weidong Le
Autophagy: Biology and Diseases : Clinical Science / / edited by Weidong Le
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XXXVI, 736 p. 50 illus., 30 illus. in color.)
Disciplina 361.32
Collana Advances in Experimental Medicine and Biology
Soggetto topico Medicine - Research
Biology - Research
Cytology
Medical sciences
Pharmacology
Biomedical Research
Cell Biology
Health Sciences
Autofàgia
Soggetto genere / forma Llibres electrònics
ISBN 981-15-4272-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Autophagy and Alzheimer’s Disease -- Autophagy and Parkinson’s Disease -- Autophagy and Motor Neuron Diseases -- Autophagy and Prion Disease -- Autophagy and Lysosome Storage Disorders -- Autophagy and Mitochondrial Encephalomyopathies -- Autophagy and Ischemic Stroke -- Autophagy and Hemorrhagic Stroke -- Autophagy and Polyglutamine Disease -- Autophagy and Epilepsy -- Autophagy in Neurodevelopmental Disorders -- Autophagy and Pituitary Adenoma -- Autophagy in Schizophrenia -- Autophagy and Hypertension -- Autophagy and Myocardial Ischemia -- Autophagy and Heart Failure -- Autophagy, Myocarditis and Cardiomyopathy -- Autophagy, Hyperlipidemia and Atherosclerosis -- Application of Autophagy in Cardiovascular Diseases -- Autophagy and Tumorigenesis -- Autophagy and Tumour Stem Cells -- Autophagy and Tumour Metastasis -- Autophagy and Tumor Cell Death -- Autophagy and Tumour Chemotherapy -- Autophagy and Tumour Radiotherapy -- Autophagy and Inflammatory Diseases -- Autophagy and Immune-related Diseases -- Autophagy and Autoimmune Diseases -- Autophagy and Bacterial Infection -- Autophagy and Viral Infection -- Autophagy and Thyroid Disease -- Autophagy and Obesity and Diabetes -- Autophagy and Obesity-related Reproductive Dysfunction -- Autophagy and Acute Kidney Injury -- Autophagy and Glomerular Diseases -- Autophagy and Diabetic Nephropathy -- Autophagy and Liver Diseases -- Autophagy and Gastrointestinal Diseases -- Chronic Obstructive Pulmonary Disease and Autophagy -- Autophagy and Pulmonary Fibrosis -- Asthma and Autophagy -- Autophagy and Other respiratory diseases -- Autophagy and Leukemia -- Autophagy and Lymphoma -- Autophagy and Myeloma -- The Function and Mechanisms of Autophagy in Traumatic Brain Injury -- The Function and Mechanisms of Autophagy in Spinal Cord Injury -- The Function and Mechanisms of Autophagy in Trauma of Other Parts of the Body -- The Prospects of Therapeutic Potential and Drug Development Targeting Autophagy in Cancer -- Progress of Anti-aging Drugs Targeting Autophagy -- Drug Development and Treatment of Autophagy in Other Diseases -- Systems Biology Approaches in Autophagy Research -- Natural Product Regulates Autophagy in Cancer -- Regulation of Autophagy in Neurodegenerative Diseases by Natural Products -- Regulation of Autophagy in Cardiovascular Diseases by Natural Products.
Record Nr. UNINA-9910416109703321
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020
Materiale a stampa
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Biochemistry of apoptosis and autophagy / / edited by Lorrie A. Kirshenbaum
Biochemistry of apoptosis and autophagy / / edited by Lorrie A. Kirshenbaum
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2022]
Descrizione fisica 1 online resource (293 pages)
Disciplina 574.87
Collana Advances in Biochemistry in Health and Disease
Soggetto topico Cytology
Apoptosi
Autofàgia
Soggetto genere / forma Llibres electrònics
ISBN 9783030787998
9783030787981
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910522926903321
Cham, Switzerland : , : Springer, , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Exercise, autophagy and chronic diseases / / Ning Chen, editor
Exercise, autophagy and chronic diseases / / Ning Chen, editor
Pubbl/distr/stampa Singapore : , : Springer, , [2021]
Descrizione fisica 1 online resource (267 pages)
Disciplina 617.1027
Soggetto topico Sports medicine
Autofàgia
Malalties cròniques
Exercici
Soggetto genere / forma Llibres electrònics
ISBN 981-16-4525-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Acknowledgments -- Contents -- Chapter 1: Molecular Processes and Regulation of Autophagy -- 1 Introduction -- 2 Molecular Mechanism of Autophagy: A Historical Interest -- 3 The Molecular Mechanisms of Autophagy in Mammals -- 3.1 Autophagy Induction -- 3.2 Autophagosome Formation -- 3.3 Fusion Between Autophagosome and Lysosome -- 4 Molecular Regulation of Autophagy Machinery -- 4.1 The mTOR-Dependent Signaling Pathway -- 4.2 mTOR-Independent Signaling Pathways -- 4.2.1 Calcium Signaling in Autophagy -- 4.2.2 Calcium-Releasing Channel Control in Autophagy Mediated by TRPML -- 4.2.3 The mTOR-Independent TRPML1 Channel -- 4.2.4 The Regulation of Autophagy Via miRNA, ROS, and JNK-Beclin1 -- 5 Conclusion -- References -- Chapter 2: Acute and Chronic Exercise on Autophagy -- 1 Introduction -- 2 Exercise and Autophagy -- 2.1 Effect of Exercise on Skeletal Muscle Autophagy -- 2.2 Effect of Exercise on Myocardial Autophagy -- 2.3 Effect of Exercise on the Regulation of Autophagy Level in Hepatocytes -- 2.4 Effect of Exercise on Brain Function -- 3 Acute Exercise-Induced Autophagy -- 3.1 Underlying Mechanism for the Effect of Acute Exercise on Skeletal Muscle Autophagy -- 3.2 Underlying Mechanism for the Effect of Acute Exercise on Myocardial Autophagy -- 4 Chronic Exercise Induces Autophagy -- 4.1 Underlying Mechanism for the Effect of Chronic Exercise on Skeletal Muscle Autophagy -- 4.2 Underlying Mechanism for the Effect of Chronic Exercise on Myocardial Autophagy -- 5 Conclusion and Prospects -- References -- Chapter 3: The Beneficial Roles of Exercise-Mediated Autophagy in T2DM -- 1 The Background of T2DM -- 2 Autophagy in Insulin Target Tissues of T2DM -- 2.1 Hepatic Autophagy in T2DM -- 2.2 Adipose Autophagy in T2DM -- 2.3 Skeletal Muscle Autophagy in T2DM -- 2.4 Pancreatic β-Cell Autophagy in T2DM.
3 Exercise-Mediated Autophagy in T2DM -- 3.1 Exercise-Mediated Autophagy Improves Insulin Sensitivity in T2DM -- 3.2 Exercise-Mediated Autophagy Maintains Mitochondrial Quality Control in T2DM -- 3.3 Exercise-Mediated Autophagy Maintains Muscle Mass and Function in T2DM -- 4 Conclusion -- References -- Chapter 4: Exercise-Induced Autophagy and Obesity -- 1 Introduction -- 2 General Characteristics and Mechanism of Autophagy -- 3 Relationship Between Autophagy and Obesity -- 3.1 Lipophagy and Obesity -- 3.2 Mitophagy and Obesity -- 3.3 Reticulophagy and Obesity -- 4 The Effect of Exercise-Induced Autophagy on Obesity -- 4.1 Endurance Exercise -- 4.2 Resistance Exercise or Combined Endurance Exercise -- 5 Exercise Interventions for Obese Patients Targeting Autophagy -- 6 Conclusion -- References -- Chapter 5: Exercise-Mediated Autophagy and Nonalcoholic Fatty Liver Disease -- 1 Introduction -- 1.1 Epidemiology and Diagnosis of Nonalcoholic Fatty Liver Disease (NAFLD) -- 1.2 Pathological Process of NAFLD -- 1.3 Autophagy in NAFLD -- 1.3.1 Autophagy Regulates Lipid Storage in Hepatocytes -- 1.3.2 Autophagy Regulates the Differentiation and Production of Adipocytes -- 2 Effect of Exercise Intervention in NAFLD and Underlying Mechanisms -- 2.1 Exercise Increases Lipid Metabolism Via Regulation of Autophagy -- 2.2 Exercise Alleviates NAFLD by Reducing Mitochondrial Oxidative Stress -- 2.3 Exercise Regulates microRNA-Mediated Autophagy in NAFLD -- 2.4 Exercise Promotes Autophagy in NAFLD by Increasing H2S Activity -- 2.5 Exercise-Mediated Autophagy Regulates Liver Fibrosis and Late-Stage NAFLD -- 3 Weight Loss Is a Feasible Strategy for NAFLD? -- 4 Exercise Prescriptions -- 5 Conclusion and Future Perspectives -- References -- Chapter 6: Exercise-Mediated Autophagy and Brain Aging -- 1 Autophagy in the Aging Process.
1.1 Autophagy Protects Against Metabolic Stress -- 1.2 Autophagy Acts as a Cell Housekeeper -- 1.3 Autophagy as a Genome Guardian -- 2 Autophagy Regulators During Aging Process -- 2.1 mTOR -- 2.2 Sirtuin (SIRT1) -- 2.3 p53 -- 3 Brain Aging -- 3.1 Characteristics of Brain Aging -- 3.1.1 Cell Senescence -- 3.1.2 Accumulation of Damaged Cellular Contents -- 3.1.3 Structural Changes in Brain During Aging Process -- 3.2 Underlying Mechanisms of Brain Aging -- 3.3 Brain Aging and Neurodegenerative Diseases -- 4 Exercise-Induced Autophagy and Brain Aging -- 4.1 Exercise and Brain Aging in Basic Research -- 4.1.1 Autophagy -- 4.1.2 Mitochondria -- 4.1.3 Inflammation -- 4.1.4 DNA Repairing -- 4.1.5 Lifespan Extension -- 4.2 Exercise and Brain Aging in Clinical Research -- 4.2.1 Brain Volume -- 4.2.2 Cognitive Capacity -- 5 Outlook and Prospects -- References -- Chapter 7: Exercise-Mediated Autophagy and Alzheimer´s Disease -- 1 The Epidemiology of AD -- 2 The Pathogenesis of AD -- 2.1 Amyloid Cascade Hypothesis -- 2.2 Tau Protein Hyperphosphorylation -- 2.3 Neuroinflammation -- 2.4 Mitophagy Dysfunction -- 2.5 Cholinergic Neurotransmitter Pathway Abnormalities -- 3 Autophagy and AD -- 3.1 Autophagy -- 3.2 The Regulatory Role of Autophagy in AD -- 3.2.1 Autophagy and Aβ -- 3.2.2 Autophagy and Tau Protein -- 3.2.3 Autophagy and Neuroinflammation -- 4 Exercise-Induced Autophagy in AD -- 4.1 Exercise Can Improve the Level of Autophagy -- 4.1.1 Exercise Can Increase the Autophagy Level of Normal Brain Cells -- 4.1.2 Exercise Can Improve the Functional Status of Autophagy in Brain with Nerve Damage -- 4.2 Exercise Can Improve AD Through Inducing Autophagy -- 4.2.1 Exercise Can Improve AD by Increasing the Activation of Autophagy -- 4.2.2 Exercise Can Improve AD by Enhancing the Degradation Function of Lysosomes.
4.2.3 Exercise Can Reduce the Deposition of AD-Like Aβ Through Autophagy -- 4.2.4 Exercise Can Reduce the Abnormal Phosphorylation of Tau by Improving Autophagy -- 4.2.5 Exercise Can Regulate Synaptic Plasticity Through Autophagy -- References -- Chapter 8: Exercise-Induced Autophagy and Parkinson´s Disease -- 1 Overview of Parkinson´s Disease (PD) -- 1.1 The Epidemiology of PD -- 1.2 The Pathogenesis of PD -- 1.3 Pathological Mechanisms of PD -- 1.3.1 Neuropathological Pathogenesis -- 1.3.2 Genetic Factors -- 1.3.3 Environmental Factors -- 1.3.4 Other Factors -- Immune Factors -- Oxidative Stress Factors -- 1.4 Current Status of Treatments -- 2 Autophagy Is Involved in PD -- 2.1 Mitophagy and PD -- 2.1.1 Parkinson´s Gene-Encoded Protein Is Involved in Mitochondrial Autophagy -- PTEN-Induced Kinase 1 (PINK1) and PARKIN Proteins Regulate Mitochondrial Autophagy -- DJ-1 Protein Regulates Mitochondrial Autophagy -- SNCA (Gene Encoding α-Synuclein) and α-Synuclein Regulate Mitochondrial Autophagy -- Leucine-Rich Repeat Kinase 2 (LRRK2) Regulates Mitochondrial Autophagy -- Glucocerebrosidase (GBA) Regulates Mitochondrial Autophagy -- ATPase Cation-Transporting 13A2 (ATP13A2) Regulates Mitochondrial Autophagy -- 2.1.2 Environmental Factors Regulate Mitochondrial Autophagy -- 2.2 The Relationship Between ALP and PD -- 2.3 The Role of microRNAs in PD -- 3 The Relationship Between Exercise and PD -- 3.1 Regulation of Exercise on Autophagy -- 3.2 The Regulatory Role of Exercise-Mediated Autophagy in PD -- References -- Chapter 9: Exercise-Mediated Autophagy in Cardiovascular Diseases -- 1 Introduction -- 2 Autophagy in Cardiovascular Diseases -- 3 Exercise-Mediated Autophagy in CVDs -- 3.1 Exercise-Mediated Autophagy in Hypertension -- 3.2 Exercise-Mediated Autophagy in Atherosclerosis -- 3.2.1 Autophagy and Atherosclerosis.
3.2.2 Exercise and Atherosclerosis -- 3.2.3 Effect of Exercise on Autophagy in Aorta -- 3.2.4 Exercise-Induced Autophagy Inhibits Atherosclerosis by Regulating Inflammatory Response and Lipid Metabolism -- 3.3 Exercise-Mediated Autophagy Alleviates Myocardial Ischemia-Reperfusion Injury -- 3.3.1 The Regulation of Autophagy During Ischemia -- 3.3.2 The Regulation of Autophagy During Reperfusion -- 3.3.3 Exercise Regulates Autophagy-Mediated Myocardial Ischemia-Reperfusion Injury -- 3.4 Exercise-Induced Autophagy in Cardioprotection -- 4 Conclusion -- References -- Chapter 10: Exercise-Induced Autophagy in the Prevention and Treatment of Sarcopenia -- 1 The Pathogenesis of Sarcopenia -- 2 The Regulation of Autophagy in Sarcopenia -- 2.1 ALS and UPS -- 2.2 Mitochondrial Quality Control -- 2.3 Satellite Cells -- 2.4 Inflammation -- 3 Exercise-Induced Autophagy Regulates Sarcopenia -- 3.1 Exercise and Sarcopenia -- 3.2 Exercise and Autophagy -- 3.3 Molecular Regulators of Exercise-Induced Autophagy -- 3.3.1 AMPK -- 3.3.2 PGC-1α -- 3.3.3 mTOR -- 3.3.4 FoxO -- 4 Exercise Advices -- 5 Conclusion -- References -- Chapter 11: Prospective Advances in Exercise-Induced Autophagy on Health -- 1 Introduction -- 2 Autophagy Pathways -- 3 Autophagy Is Activated During Exercise -- 4 Molecular Mechanisms of Exercise-Induced Autophagy -- 4.1 AMPK-mTOR-ULK1 Signal Pathway -- 4.2 Akt-mTOR Signal Pathway -- 4.3 Beclin1-Bcl-2 Complex -- 4.4 FoxO Family -- 4.5 Other Signal Pathways -- 5 Mitophagy -- 6 Exercise Adaptation for Health Promotion Through Induced Autophagy/Mitophagy -- 6.1 Exercise Performance -- 6.2 Skeletal Muscle Mass -- 6.3 Cardiovascular Adaptation -- 6.4 Glycolipid Metabolism Regulation -- 6.5 Mitochondrial Adaptation -- 6.6 Disease Status -- 7 Conclusion and Future Perspective -- References.
Chapter 12: Exercise Mimetic Pills for Chronic Diseases Based on Autophagy.
Record Nr. UNINA-9910502652503321
Singapore : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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