Acetylsalicylic acid / / Karsten Schrör |
Autore | Schrör Karsten |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016 |
Descrizione fisica | 1 online resource (477 p.) |
Disciplina | 854.914080356 |
Soggetto topico | Aspirin |
ISBN |
3-527-68504-9
3-527-68502-2 3-527-68505-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Acetylsalicylic Acid; Contents; Preface; 1: General Aspects; 2: Pharmacology; 3: Toxicity and Drug Safety; 4: Clinical Applications of Aspirin; Appendix 1: Abbreviations; Appendix 2: Selected Clinical Trials and Their Acronyms - Only Published Trials; Index; End User License Agreement; 1.1 History; 1.2 Chemistry; 2.1 Pharmacokinetics; 2.2 Cellular Modes of Action; 2.3 Actions on Organs and Tissues; 3.1 Systemic Side Effects; 3.2 Organ Toxicity; 3.3 Hypersensitivity to Aspirin and Reye's Syndrome; 4.1 Thromboembolic Diseases; 4.2 Pain, Fever, and Inflammatory Diseases
4.3 Further Potential Clinical Indications1.1.1 From Willow Bark to Salicylic Acid; 1.1.2 Synthesis of Acetylated Salicylic Acid and First Medical Use; 1.1.3 Search for Pharmacological Modes of Action; 1.1.4 Clinical Applications: A Piece of History; 1.1.5 Current Research Topics; 1.2.1 Structures and Chemical Properties of Salicylates; 1.2.2 Determination of Salicylates; 2.1.1 Absorption and Distribution; 2.1.2 Biotransformation and Excretion; 2.2.1 Inhibition of Cyclooxygenases; 2.2.2 COX-Independent Actions of Aspirin on Cell Function; 2.2.3 Energy Metabolism 2.3.1 Hemostasis and Thrombosis2.3.2 Inflammation, Pain, and Fever; 2.3.3 Aspirin and Malignancies; 3.1.1 Acute and Chronic Toxicity; 3.1.2 Bleeding Time and Bleeding Risk; 3.1.3 Safety Pharmacology in Particular Life Situations; 3.2.1 Gastrointestinal (GI) Tract; 3.2.2 Liver; 3.2.3 Kidney; 3.2.4 Audiovestibular System; 3.3.1 Aspirin-Exacerbated Respiratory Disease (AERD, ""Aspirin-Induced Asthma""); 3.3.2 Urticaria/Angioedema and Stevens-Johnson and Lyell's Syndrome; 3.3.3 Reye's Syndrome; 4.1.1 Coronary Vascular Disease; 4.1.2 Cerebrovascular Diseases; 4.1.3 Peripheral Arterial Disease 4.1.4 Venous Thrombosis4.1.5 Preeclampsia; 4.1.6 Aspirin ``Resistance ́́(High On-Aspirin Treatment Platelet Reactivity); 4.2.1 Analgesia and Antipyresis; 4.2.2 Inflammatory Diseases; 4.2.3 Kawasaki's Disease; 4.3.1 Colorectal Cancer; 4.3.2 Alzheimer's Disease; 1.1.1.1 Anti-Inflammatory and Analgesic Effects of Willow Bark and Leaves; 1.1.1.2 Salicylates as the Active Ingredients of Willow Bark and Other Natural Sources; 1.1.1.3 Chemical Synthesis of Salicylic Acid; Summary; References; 1.1.2.1 The Invention of Acetylated Salicylic Acid 1.1.2.2 Introduction of Acetylsalicylic Acid into the ClinicsSummary; References; 1.1.3.1 Salicylates and Energy Metabolism of the Cell; 1.1.3.2 Aspirin and Prostaglandin Formation; 1.1.3.3 Aspirin and COX-2; Summary; References; 1.1.4.1 Anti-Inflammatory/Analgesic Actions; 1.1.4.2 Antiplatelet/Antithrombotic Actions and the Bleeding Tendency; 1.1.4.3 Aspirin and the History of Prevention of Myocardial Infarction and Stroke; Summary; References; 1.1.5.1 Clinical Research; 1.1.5.2 Basic Research; Summary; References; 1.2.1.1 Salicin: The Natural Salicylate; 1.2.1.2 Salicylates in Clinical Use 1.2.1.3 Aspirin Formulations |
Record Nr. | UNINA-9910134856403321 |
Schrör Karsten | ||
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Acetylsalicylic acid / / Karsten Schrör |
Autore | Schrör Karsten |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016 |
Descrizione fisica | 1 online resource (477 p.) |
Disciplina | 854.914080356 |
Soggetto topico | Aspirin |
ISBN |
3-527-68504-9
3-527-68502-2 3-527-68505-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Acetylsalicylic Acid; Contents; Preface; 1: General Aspects; 2: Pharmacology; 3: Toxicity and Drug Safety; 4: Clinical Applications of Aspirin; Appendix 1: Abbreviations; Appendix 2: Selected Clinical Trials and Their Acronyms - Only Published Trials; Index; End User License Agreement; 1.1 History; 1.2 Chemistry; 2.1 Pharmacokinetics; 2.2 Cellular Modes of Action; 2.3 Actions on Organs and Tissues; 3.1 Systemic Side Effects; 3.2 Organ Toxicity; 3.3 Hypersensitivity to Aspirin and Reye's Syndrome; 4.1 Thromboembolic Diseases; 4.2 Pain, Fever, and Inflammatory Diseases
4.3 Further Potential Clinical Indications1.1.1 From Willow Bark to Salicylic Acid; 1.1.2 Synthesis of Acetylated Salicylic Acid and First Medical Use; 1.1.3 Search for Pharmacological Modes of Action; 1.1.4 Clinical Applications: A Piece of History; 1.1.5 Current Research Topics; 1.2.1 Structures and Chemical Properties of Salicylates; 1.2.2 Determination of Salicylates; 2.1.1 Absorption and Distribution; 2.1.2 Biotransformation and Excretion; 2.2.1 Inhibition of Cyclooxygenases; 2.2.2 COX-Independent Actions of Aspirin on Cell Function; 2.2.3 Energy Metabolism 2.3.1 Hemostasis and Thrombosis2.3.2 Inflammation, Pain, and Fever; 2.3.3 Aspirin and Malignancies; 3.1.1 Acute and Chronic Toxicity; 3.1.2 Bleeding Time and Bleeding Risk; 3.1.3 Safety Pharmacology in Particular Life Situations; 3.2.1 Gastrointestinal (GI) Tract; 3.2.2 Liver; 3.2.3 Kidney; 3.2.4 Audiovestibular System; 3.3.1 Aspirin-Exacerbated Respiratory Disease (AERD, ""Aspirin-Induced Asthma""); 3.3.2 Urticaria/Angioedema and Stevens-Johnson and Lyell's Syndrome; 3.3.3 Reye's Syndrome; 4.1.1 Coronary Vascular Disease; 4.1.2 Cerebrovascular Diseases; 4.1.3 Peripheral Arterial Disease 4.1.4 Venous Thrombosis4.1.5 Preeclampsia; 4.1.6 Aspirin ``Resistance ́́(High On-Aspirin Treatment Platelet Reactivity); 4.2.1 Analgesia and Antipyresis; 4.2.2 Inflammatory Diseases; 4.2.3 Kawasaki's Disease; 4.3.1 Colorectal Cancer; 4.3.2 Alzheimer's Disease; 1.1.1.1 Anti-Inflammatory and Analgesic Effects of Willow Bark and Leaves; 1.1.1.2 Salicylates as the Active Ingredients of Willow Bark and Other Natural Sources; 1.1.1.3 Chemical Synthesis of Salicylic Acid; Summary; References; 1.1.2.1 The Invention of Acetylated Salicylic Acid 1.1.2.2 Introduction of Acetylsalicylic Acid into the ClinicsSummary; References; 1.1.3.1 Salicylates and Energy Metabolism of the Cell; 1.1.3.2 Aspirin and Prostaglandin Formation; 1.1.3.3 Aspirin and COX-2; Summary; References; 1.1.4.1 Anti-Inflammatory/Analgesic Actions; 1.1.4.2 Antiplatelet/Antithrombotic Actions and the Bleeding Tendency; 1.1.4.3 Aspirin and the History of Prevention of Myocardial Infarction and Stroke; Summary; References; 1.1.5.1 Clinical Research; 1.1.5.2 Basic Research; Summary; References; 1.2.1.1 Salicin: The Natural Salicylate; 1.2.1.2 Salicylates in Clinical Use 1.2.1.3 Aspirin Formulations |
Record Nr. | UNINA-9910830373403321 |
Schrör Karsten | ||
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Aspirin or nonsteroidal anti-inflammatory drugs for the primary prevention of colorectal cancer [[electronic resource]] |
Pubbl/distr/stampa | [Rockville, Md.] : , : Agency for Healthcare Research and Quality, , [2007] |
Descrizione fisica | 1 electronic text : HTML file |
Soggetto topico |
Colon (Anatomy) - Cancer - Prevention
Rectum - Cancer - Prevention Aspirin Anti-inflammatory agents |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910696187103321 |
[Rockville, Md.] : , : Agency for Healthcare Research and Quality, , [2007] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Keep out of reach of children : Reye's syndrome, aspirin, and the politics of public health / / Mark A. Largent |
Autore | Largent Mark A. |
Edizione | [First edition.] |
Pubbl/distr/stampa | New York, New York : , : Bellevue Literary Press, , 2015 |
Descrizione fisica | 1 online resource (273 p.) |
Disciplina |
618.92
618.9283 |
Collana | Bellevue Literary Press Pathography |
Soggetto topico |
Reye's syndrome
Public health - Political aspects Aspirin |
ISBN | 1-934137-89-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Table of Contents; Prologue; Chapter One: The Discovery of Reye's Syndrome; Chapter Two: Toxins: The Obvious Cause; Chapter Three: The Deadly Mist; Chapter Four: The Front Line in the Battle against Reye's Syndrome; Chapter Five: The Aspirin Hypothesis; Chapter Six: The Aspirin Industry Responds; Chapter Seven: The Rise of Labels and the Fall of Reye's; Chapter Eight: Labels, At Last; Chapter Nine: Triumph and Dissent; Chapter Ten: The Politics of Public Health; Acknowledgments; Notes; Index |
Record Nr. | UNINA-9910787428803321 |
Largent Mark A. | ||
New York, New York : , : Bellevue Literary Press, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Keep out of reach of children : Reye's syndrome, aspirin, and the politics of public health / / Mark A. Largent |
Autore | Largent Mark A. |
Edizione | [First edition.] |
Pubbl/distr/stampa | New York, New York : , : Bellevue Literary Press, , 2015 |
Descrizione fisica | 1 online resource (273 p.) |
Disciplina |
618.92
618.9283 |
Collana | Bellevue Literary Press Pathography |
Soggetto topico |
Reye's syndrome
Public health - Political aspects Aspirin |
ISBN | 1-934137-89-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Table of Contents; Prologue; Chapter One: The Discovery of Reye's Syndrome; Chapter Two: Toxins: The Obvious Cause; Chapter Three: The Deadly Mist; Chapter Four: The Front Line in the Battle against Reye's Syndrome; Chapter Five: The Aspirin Hypothesis; Chapter Six: The Aspirin Industry Responds; Chapter Seven: The Rise of Labels and the Fall of Reye's; Chapter Eight: Labels, At Last; Chapter Nine: Triumph and Dissent; Chapter Ten: The Politics of Public Health; Acknowledgments; Notes; Index |
Record Nr. | UNINA-9910826192803321 |
Largent Mark A. | ||
New York, New York : , : Bellevue Literary Press, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Mismatch repair deficient cancers diagnosis, treatment and prevention / / John Burn |
Autore | Burn John, MD, MRCP |
Pubbl/distr/stampa | London, : Henry Stewart Talks, 2014 |
Descrizione fisica | 1 online resource (1 streaming video file (44 min.) : color, sound) |
Collana | Molecular genetics of human disease |
Soggetto topico |
Aspirin
Cancer - Genetic aspects Colon (Anatomy) - Cancer - Genetic aspects Colon (Anatomy) - Cancer - Treatment Medical genetics Molecular genetics Rectum - Cancer - Genetic aspects Rectum - Cancer - Treatment Aspirin - therapeutic use Biomarkers Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics Colorectal Neoplasms - therapy Colorectal Neoplasms, Hereditary Nonpolyposis DNA Mismatch Repair Genetics, Medical Microsatellite Instability Microsatellite Repeats |
Formato | Videoregistrazioni |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents: Lynch syndrome (underlying single gene defect) -- Microsatellites -- Important genes containing repeat sequences -- MSI testing (5 marker panel) -- Mismatch repair (MMR) -- The genomic pathogenesis of colorectal cancer (CRC) -- EGFR and BRAF mutant inhibition -- BRAF colon cancer project -- Methotrexate & MMR deficient tumours -- Africans & bowel cancer (Dennis Burkitt) -- Cancer prevention program (CaPP) -- NSAIDs and reduced colorectal cancer risk -- Aspirin effect on polyps in FAP and colorectal adenoma -- The prevention paradox -- CaPP2 (Colorectal & Lynch syndrome cancers) -- Meta-analysis of cancer deaths with aspirin treatment -- CRCs in people on aspirin (mostly COX2 negative) -- Individual response to aspirin in cancer prevention -- History of salicylate as an essential nutrient -- CaPP3 study -- Peptides created by slippage in microsatellite coding -- Antibodies as a possible biomarker for Lynch syndrome -- The Micoryx vaccine. |
Record Nr. | UNINA-9910596997903321 |
Burn John, MD, MRCP | ||
London, : Henry Stewart Talks, 2014 | ||
Videoregistrazioni | ||
Lo trovi qui: Univ. Federico II | ||
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