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Advanced Therapy for Hepatitis C [[electronic resource]]
| Advanced Therapy for Hepatitis C [[electronic resource]] |
| Autore | McCaughan Geoffrey W |
| Pubbl/distr/stampa | Hoboken, : Wiley, 2011 |
| Descrizione fisica | 1 online resource (233 p.) |
| Disciplina |
616.3/62306
616.362306 |
| Altri autori (Persone) |
McHutchisonJohn
PawlotskyJean-Michel |
| Soggetto topico |
Antiviral agents
Antiviral Agents - therapeutic use Antiviral Agents -- therapeutic use Hepatitis C - therapy Hepatitis C -- therapy Hepatitis C - Treatment Hepatitis C -- Treatment Hepatitis, Viral, Human Flaviviridae Infections Anti-Infective Agents RNA Virus Infections Therapeutic Uses Virus Diseases Hepatitis Diseases Liver Diseases Pharmacologic Actions Chemical Actions and Uses Digestive System Diseases Antiviral Agents Hepatitis C Medicine Health & Biological Sciences Gastroenterology |
| ISBN |
1-283-28323-9
9786613283238 1-4443-4634-2 1-4443-4631-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension 18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index |
| Record Nr. | UNINA-9910139591503321 |
McCaughan Geoffrey W
|
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| Hoboken, : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advanced therapy for hepatitis C / / edited by Geoffrey W. McCaughan, John G. McHutchison, Jean-Michel Pawlotsky
| Advanced therapy for hepatitis C / / edited by Geoffrey W. McCaughan, John G. McHutchison, Jean-Michel Pawlotsky |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (233 p.) |
| Disciplina | 616.3/62306 |
| Altri autori (Persone) |
McCaughanGeoffrey W
McHutchisonJ. G PawlotskyJean-Michel |
| Soggetto topico |
Hepatitis C - Treatment
Antiviral agents |
| ISBN |
1-283-28323-9
9786613283238 1-4443-4634-2 1-4443-4631-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension 18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index |
| Record Nr. | UNINA-9910809498803321 |
| Chichester, West Sussex, : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910457252903321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910784598503321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in studies on enzyme inhibitors as drugs . Volume 1 Anticancer and antiviral drugs / / Satya P. Gupta, editor
| Advances in studies on enzyme inhibitors as drugs . Volume 1 Anticancer and antiviral drugs / / Satya P. Gupta, editor |
| Pubbl/distr/stampa | New York : , : Nova Biomedical, , [2017] |
| Descrizione fisica | 1 online resource (375 pages) : illustrations (some color) |
| Collana | Pharmacology - research, safety testing and regulation |
| Soggetto topico |
Antiviral agents
Cancer - Treatment |
| ISBN | 1-5361-0520-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910159436103321 |
| New York : , : Nova Biomedical, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antimicrobial agents and chemotherapy : AAC
| Antimicrobial agents and chemotherapy : AAC |
| Pubbl/distr/stampa | Washington, DC, : American Society for Microbiology |
| Disciplina | 615 |
| Soggetto topico |
Antibiotics
Chemotherapy Anti-infective agents Antiviral agents Drug Therapy Antiviral Agents Anti-Bacterial Agents Antibiotiques Chimiothérapie Antiinfectieux Antiviraux |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1098-6596 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | AAC |
| Record Nr. | UNISA-996213110103316 |
| Washington, DC, : American Society for Microbiology | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Antimicrobial agents and chemotherapy : AAC
| Antimicrobial agents and chemotherapy : AAC |
| Pubbl/distr/stampa | Washington, DC, : American Society for Microbiology |
| Disciplina | 615 |
| Soggetto topico |
Antibiotics
Chemotherapy Anti-infective agents Antiviral agents Drug Therapy Antiviral Agents Anti-Bacterial Agents Antibiotiques Chimiothérapie Antiinfectieux Antiviraux |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1098-6596 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | AAC |
| Record Nr. | UNINA-9910144060403321 |
| Washington, DC, : American Society for Microbiology | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antiviral agents bulletin
| Antiviral agents bulletin |
| Pubbl/distr/stampa | [Washington, D.C., U.S.A.], : [OMEC International], [©1988]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 615 |
| Soggetto topico |
Antiviral agents
Antiviral agents - Patents |
| Soggetto genere / forma |
Abstracts.
Periodicals. |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910895838003321 |
| [Washington, D.C., U.S.A.], : [OMEC International], [©1988]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antiviral chemistry & chemotherapy
| Antiviral chemistry & chemotherapy |
| Pubbl/distr/stampa | Oxford, UK ; ; Boston, : Blackwell Scientific Publications, ©1990- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616.92506 |
| Soggetto topico |
Chemotherapy
Antiviral agents Antiviral agents - Periodicals Antiviral Agents Virus Diseases - drug therapy |
| Soggetto non controllato | Antivirals |
| ISSN | 2040-2066 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antiviral chemistry and chemotherapy |
| Record Nr. | UNINA-9910142562103321 |
| Oxford, UK ; ; Boston, : Blackwell Scientific Publications, ©1990- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antiviral chemistry & chemotherapy
| Antiviral chemistry & chemotherapy |
| Pubbl/distr/stampa | Oxford, UK ; ; Boston, : Blackwell Scientific Publications, ©1990- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616.92506 |
| Soggetto topico |
Chemotherapy
Antiviral agents Antiviral agents - Periodicals Antiviral Agents Virus Diseases - drug therapy |
| Soggetto non controllato | Antivirals |
| ISSN | 2040-2066 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antiviral chemistry and chemotherapy |
| Record Nr. | UNISA-996204837803316 |
| Oxford, UK ; ; Boston, : Blackwell Scientific Publications, ©1990- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
