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Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties
Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties
Autore Zirngibl Ludwig
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH Imprint, 1998
Descrizione fisica 1 online resource (300 pages)
Disciplina 547.593
Soggetto topico Antifungal agents
Organic compounds
Pyrroles
Fungicides
ISBN 1-280-56090-8
9786610560905
3-527-60268-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction : scope, chronology and statistics, beneficial side effects, acknowledgements -- 1-(Hydrogen-alkyl-aryl-heterocyclyl-arylalkyl-heterocyclylalkyl-diphenylalkyl- and trityl)l-H-azoles -- 1-(Mono- di- and trihydroxyalkyl- and alkenyl)-1H-azoles, their thio analogs and derivatives -- 1-(Oxo-alkyl-oxo-alkenyl, hydroxyalkylcarbonyl and dioxoalkyl)-1H-azoles and their derivatives -- 1H-Azoles or 1H-azol-1-ylalkyl compounds with a nitrogen functional group -- x-(1H-Azol-1-yl)methyl-isoxazolidines, oxazolines, -oxazolidines, -oxetanes, 1,3-dioxolanes, -morpholines, 1,3-dioxanes, -tetrahydrofurans, their thioderivatives and homologs -- 1H-Azol-1-yl-boron, -silicon, -germanium, tin-phosphorus-oxygen and sulfur compounds.
Record Nr. UNINA-9910830704603321
Zirngibl Ludwig  
[Place of publication not identified], : Wiley VCH Imprint, 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties
Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties
Autore Zirngibl Ludwig
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH Imprint, 1998
Descrizione fisica 1 online resource (300 pages)
Disciplina 547.593
Soggetto topico Antifungal agents
Organic compounds
Pyrroles
Fungicides
ISBN 1-280-56090-8
9786610560905
3-527-60268-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction : scope, chronology and statistics, beneficial side effects, acknowledgements -- 1-(Hydrogen-alkyl-aryl-heterocyclyl-arylalkyl-heterocyclylalkyl-diphenylalkyl- and trityl)l-H-azoles -- 1-(Mono- di- and trihydroxyalkyl- and alkenyl)-1H-azoles, their thio analogs and derivatives -- 1-(Oxo-alkyl-oxo-alkenyl, hydroxyalkylcarbonyl and dioxoalkyl)-1H-azoles and their derivatives -- 1H-Azoles or 1H-azol-1-ylalkyl compounds with a nitrogen functional group -- x-(1H-Azol-1-yl)methyl-isoxazolidines, oxazolines, -oxazolidines, -oxetanes, 1,3-dioxolanes, -morpholines, 1,3-dioxanes, -tetrahydrofurans, their thioderivatives and homologs -- 1H-Azol-1-yl-boron, -silicon, -germanium, tin-phosphorus-oxygen and sulfur compounds.
Record Nr. UNINA-9910841227403321
Zirngibl Ludwig  
[Place of publication not identified], : Wiley VCH Imprint, 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antifungal metabolites from plants / / Mehdi Razzaghi-Abyaneh, Mahendra Rai, editors
Antifungal metabolites from plants / / Mehdi Razzaghi-Abyaneh, Mahendra Rai, editors
Edizione [1st ed. 2013.]
Pubbl/distr/stampa New York : , : Springer, , 2013
Descrizione fisica 1 online resource (xiv, 469 pages) : illustrations (some color)
Disciplina 581.873
616.014
Collana Gale eBooks
Soggetto topico Medicinal plants
Antifungal agents
ISBN 3-642-38076-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Antifungal Compounds From Latin American Plants -- Antifungal Plants of Iran: An Insight into Ecology, Chemistry and Molecular Biology -- Antifungal Property of Selected Nigerian Medicinal Plants -- Review   of the Antifungal Potential of African Medicinal Plants -- Natural products as potential resources for antifungal substances - A survey -- Recent advances on Medicinal plants with Antifungal Activity -- Recent progress in research on plant antifungal proteins: a review -- Antifungal Metabolites of Endophytic Fungi -- Combining plant essential oils and antimycotics in coping with antimycotic-resistant Candida species -- Flavonoids as Antifungal Agents.-   Antifungal Metabolites from Medicinal Plants used in  Ayurvedic System of Medicine In India --  Plants Used In Folk Medicine of Bangladesh For Treatment of Tinea Infections -- Usefulness of Plant Derived Products to Protect Rice Against Fungi in Western Europe -- Plant bioactive metabolites for cereal protection against fungal pathogens -- Plant essential oils as antifungal treatments on the postharvest of fruit and vegetables -- Fruit processing byproducts as a source of natural antifungal compounds.
Record Nr. UNINA-9910736983203321
New York : , : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
Pubbl/distr/stampa Norfolk, England : , : Caister Academic Press, , [2015]
Descrizione fisica 1 online resource (346 p.)
Disciplina 616.969061
Soggetto topico Immunotherapy
Antifungal agents
Biofilms
Soggetto genere / forma Electronic books.
ISBN 1-910190-02-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts
Fungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-α sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function
Cell-free β-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance
Introduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings
Chemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets
Introduction
Record Nr. UNINA-9910460916903321
Norfolk, England : , : Caister Academic Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
Pubbl/distr/stampa Norfolk, England : , : Caister Academic Press, , [2015]
Descrizione fisica 1 online resource (346 p.)
Disciplina 616.969061
Soggetto topico Immunotherapy
Antifungal agents
Biofilms
ISBN 1-910190-02-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts
Fungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-α sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function
Cell-free β-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance
Introduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings
Chemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets
Introduction
Record Nr. UNINA-9910787429403321
Norfolk, England : , : Caister Academic Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
Pubbl/distr/stampa Norfolk, England : , : Caister Academic Press, , [2015]
Descrizione fisica 1 online resource (346 p.)
Disciplina 616.969061
Soggetto topico Immunotherapy
Antifungal agents
Biofilms
ISBN 1-910190-02-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts
Fungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-α sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function
Cell-free β-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance
Introduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings
Chemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets
Introduction
Record Nr. UNINA-9910821292903321
Norfolk, England : , : Caister Academic Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antimicrobial Agents : Antibacterials and Antifungals / / edited by André Bryskier
Antimicrobial Agents : Antibacterials and Antifungals / / edited by André Bryskier
Pubbl/distr/stampa Washington, District of Columbia : , : John Wiley & Sons, Inc., , 2014
Descrizione fisica 1 online resource (xxx, 1426 pages) : illustrations
Disciplina 615.329
Soggetto topico Antibiotics
Antifungal agents
Antibacterial agents
Anti-infective agents
ISBN 1-68367-191-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Foreword; Foreword to the First Edition, Revised; Foreword to the First Edition; Preface; Contributors; 1 Historical Review of Antibacterial Chemotherapy; 2 Antibiotics and Antibacterial Agents: Classifications and Structure-Activity Relationship; 3 Epidemiology of Resistance to Antibacterial Agents; 4 Development of an Antibiotic: Microbiology; 5 Penicillins; 6 Cephems for Parenteral Use; 7 Oral Cephalosporins; 8 Carbapenems; 9 Penems; 10 Monocyclic ß-Lactams; 11 ß-Lactam Prodrugs; 12 Peptidoglycan Synthesis Inhibitors; 13 ß-Lactamase Inhibitors. 14 ß-Lactamase Inhibitors under Research15?-Lactams and Derivatives; 16 Aminocyclitol Aminoglycosides; 17 Spectinomycin; 18 Macrolides; 19 Ketolides; 20 Streptogramins; 21 Lincosamines; 22 Oxazolidinones; 23 Fusidic Acid; 24 Tetracyclines; 25 Tetracyclines under Investigation; 26 Fluoroquinolones; 27 DNA Gyrase Inhibitors Other Than Fluoroquinolones; 28 Codrugs; 29 Coumarin Antibiotics: Novobiocin, Coumermycin, and Clorobiocin; 30 Peptide. 14 β-Lactamase Inhibitors under Research15 γ-Lactams and Derivatives; 16 Aminocyclitol Aminoglycosides; 17 Spectinomycin; 18 Macrolides; 19 Ketolides; 20 Streptogramins; 21 Lincosamines; 22 Oxazolidinones; 23 Fusidic Acid; 24 Tetracyclines; 25 Tetracyclines under Investigation; 26 Fluoroquinolones; 27 DNA Gyrase Inhibitors Other Than Fluoroquinolones; 28 Codrugs; 29 Coumarin Antibiotics: Novobiocin, Coumermycin, and Clorobiocin; 30 Peptide Antibiotics; 31 Glycopeptides and Lipoglycopeptides; 32 Ansamycins; 33 Phenicols; 34 5-Nitroimidazoles. Contents; Foreword; Foreword to the First Edition, Revised; Foreword to the First Edition; Preface; Contributors; 1 Historical Review of Antibacterial Chemotherapy; 2 Antibiotics and Antibacterial Agents: Classifications and Structure-Activity Relationship; 3 Epidemiology of Resistance to Antibacterial Agents; 4 Development of an Antibiotic: Microbiology; 5 Penicillins; 6 Cephems for Parenteral Use; 7 Oral Cephalosporins; 8 Carbapenems; 9 Penems; 10 Monocyclic β-Lactams; 11 β-Lactam Prodrugs; 12 Peptidoglycan Synthesis Inhibitors; 13 β-Lactamase Inhibitors.
Record Nr. UNINA-9910555017003321
Washington, District of Columbia : , : John Wiley & Sons, Inc., , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Performance characteristics of borate fatty acid formulations as mold inhibitors / / Robert D. Coleman, Vina W. Yang, Carol A. Clausen
Performance characteristics of borate fatty acid formulations as mold inhibitors / / Robert D. Coleman, Vina W. Yang, Carol A. Clausen
Autore Coleman Robert D.
Pubbl/distr/stampa Madison, WI : , : United States Department of Agriculture, Forest Service, Forest Products Laboratory, , 2013
Descrizione fisica 1 online resource (6 pages)
Collana Research paper FPL-RP
Soggetto topico Wood preservatives
Antifungal agents
Molds (Fungi) - Control
Wood-decaying fungi - Control
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910704657403321
Coleman Robert D.  
Madison, WI : , : United States Department of Agriculture, Forest Service, Forest Products Laboratory, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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