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Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties
| Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties |
| Autore | Zirngibl Ludwig |
| Pubbl/distr/stampa | [Place of publication not identified], : Wiley VCH Imprint, 1998 |
| Descrizione fisica | 1 online resource (300 pages) |
| Disciplina | 547.593 |
| Soggetto topico |
Antifungal agents
Organic compounds Pyrroles Fungicides |
| ISBN |
1-280-56090-8
9786610560905 3-527-60268-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction : scope, chronology and statistics, beneficial side effects, acknowledgements -- 1-(Hydrogen-alkyl-aryl-heterocyclyl-arylalkyl-heterocyclylalkyl-diphenylalkyl- and trityl)l-H-azoles -- 1-(Mono- di- and trihydroxyalkyl- and alkenyl)-1H-azoles, their thio analogs and derivatives -- 1-(Oxo-alkyl-oxo-alkenyl, hydroxyalkylcarbonyl and dioxoalkyl)-1H-azoles and their derivatives -- 1H-Azoles or 1H-azol-1-ylalkyl compounds with a nitrogen functional group -- x-(1H-Azol-1-yl)methyl-isoxazolidines, oxazolines, -oxazolidines, -oxetanes, 1,3-dioxolanes, -morpholines, 1,3-dioxanes, -tetrahydrofurans, their thioderivatives and homologs -- 1H-Azol-1-yl-boron, -silicon, -germanium, tin-phosphorus-oxygen and sulfur compounds. |
| Record Nr. | UNINA-9910830704603321 |
Zirngibl Ludwig
|
||
| [Place of publication not identified], : Wiley VCH Imprint, 1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties
| Antifungal Azoles: A Comprehensive Survey of Their Structures and Properties |
| Autore | Zirngibl Ludwig |
| Pubbl/distr/stampa | [Place of publication not identified], : Wiley VCH Imprint, 1998 |
| Descrizione fisica | 1 online resource (300 pages) |
| Disciplina | 547.593 |
| Soggetto topico |
Antifungal agents
Organic compounds Pyrroles Fungicides |
| ISBN |
1-280-56090-8
9786610560905 3-527-60268-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction : scope, chronology and statistics, beneficial side effects, acknowledgements -- 1-(Hydrogen-alkyl-aryl-heterocyclyl-arylalkyl-heterocyclylalkyl-diphenylalkyl- and trityl)l-H-azoles -- 1-(Mono- di- and trihydroxyalkyl- and alkenyl)-1H-azoles, their thio analogs and derivatives -- 1-(Oxo-alkyl-oxo-alkenyl, hydroxyalkylcarbonyl and dioxoalkyl)-1H-azoles and their derivatives -- 1H-Azoles or 1H-azol-1-ylalkyl compounds with a nitrogen functional group -- x-(1H-Azol-1-yl)methyl-isoxazolidines, oxazolines, -oxazolidines, -oxetanes, 1,3-dioxolanes, -morpholines, 1,3-dioxanes, -tetrahydrofurans, their thioderivatives and homologs -- 1H-Azol-1-yl-boron, -silicon, -germanium, tin-phosphorus-oxygen and sulfur compounds. |
| Record Nr. | UNINA-9910877667203321 |
|
Zirngibl Ludwig
|
||
| [Place of publication not identified], : Wiley VCH Imprint, 1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
| Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (346 p.) |
| Disciplina | 616.969061 |
| Soggetto topico |
Immunotherapy
Antifungal agents Biofilms |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-910190-02-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts
Fungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-α sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function Cell-free β-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance Introduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings Chemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets Introduction |
| Record Nr. | UNINA-9910460916903321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
| Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (346 p.) |
| Disciplina | 616.969061 |
| Soggetto topico |
Immunotherapy
Antifungal agents Biofilms |
| ISBN | 1-910190-02-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts
Fungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-α sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function Cell-free β-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance Introduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings Chemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets Introduction |
| Record Nr. | UNINA-9910787429403321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France
| Antifungals : from genomics to resistance and the development of novel agents / / edited by Alix T. Coste, Institute of Microbiology, University Hospital Lausanne, and University Hospital Center, Lausanne, Switzerland, and Patrick Vandeputte, Host-Pathogen Interactions Study Group, UPRES-EA 3142, L'UNAM Angers University, and Parasitology-Mycology Laboratory, University Hospital Center, Angers, France |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (346 p.) |
| Disciplina | 616.969061 |
| Soggetto topico |
Immunotherapy
Antifungal agents Biofilms |
| ISBN | 1-910190-02-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Preface; 1: Molecular Mechanisms of Resistance of Candida spp. to Membrane-targeting Antifungals; Introduction; Azoles; Non-azole ergosterol biosynthesis inhibitors; Polyenes; Concluding remarks; 2: Point Mutations and Membrane-targeting Antifungal Resistance in Aspergillus fumigatus and Other Non-Candida Species; Introduction; Aspergillus fumigatus azole resistance in clinical settings; The molecular target of azoles, allylamines and polyenes: ergosterol and ergosterol biosynthesis pathway; Differences in ergosterol pathway between Aspergillus spp. and yeasts
Fungal 14-a sterol demethylases (SDMs): the main target for azole antifungalsA. fumigatus azole susceptibility patterns and mechanisms of azole resistance linked with CYP51 point mutations; Azole resistance in non-fumigatus Aspergillus; Azole secondary resistance linked with point mutations in the 14-α sterol demethylase enzyme in non-Candida and non-Aspergillus species; Polyene resistance; Resistance to allylamines; General conclusion; 3: Echinocandins: Resistance Mechanisms; Introduction; Structures; Echinocandin target: Fks1; Fks gene family; Fks1 structure-function Cell-free β-1,3-glucan synthase systemsEchinocandin uptake and efflux; Acquired echinocandin resistance: Fks hot spots 1 and 2; Differential echinocandin resistance: discovery of hot spot 3; Impact of Fks heterozygosity and redundancy on acquired resistance; Fks-independent acquired echinocandin resistance; Intrinsic echinocandin resistance: hot spot 1 substitutions; Intrinsic echinocandin resistance: hot spot 3 substitutions; Intrinsic resistance: mechanism to be determined; Stage-specific intrinsic resistance; Conclusions and future prospects; 4: Biofilms and Antifungal Resistance Introduction to fungal biofilmsFungal biofilm infections of humans; Current standard of care for fungal biofilm infections; Mechanisms of fungal biofilm drug resistance; Challenges and strategies to developing therapeutics for fungal biofilm infections; 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents; Introduction; In vitro and in vivo combinations with known antifungal agents; In vitro and in vivo combinations of non-antifungals with known antifungal agents; Systematic drug combination screenings Chemogenetic approaches in the exploration of drug interaction mechanismsConclusions; 6: Approaches to Detect Alternative Mechanisms of Resistance to Systemic Antifungals; Introduction; 'Omics' approaches; Mutants collections screening; Comparison with others species; Concluding remarks; 7: New Antifungal Discovery from Existing Chemical Compound Collections; Introduction; A new career for acetylsalicylic acid as an antifungal; Other non-traditional antimicrobial agents; Conclusion and future perspectives; 8: Exploring New Insights into Fungal Biology as Novel Antifungal Drug Targets Introduction |
| Record Nr. | UNINA-9910821292903321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antimicrobial Agents : Antibacterials and Antifungals / / edited by André Bryskier
| Antimicrobial Agents : Antibacterials and Antifungals / / edited by André Bryskier |
| Pubbl/distr/stampa | Washington, District of Columbia : , : John Wiley & Sons, Inc., , 2014 |
| Descrizione fisica | 1 online resource (xxx, 1426 pages) : illustrations |
| Disciplina | 615.329 |
| Soggetto topico |
Antibiotics
Antifungal agents Antibacterial agents Anti-infective agents |
| ISBN | 1-68367-191-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents; Foreword; Foreword to the First Edition, Revised; Foreword to the First Edition; Preface; Contributors; 1 Historical Review of Antibacterial Chemotherapy; 2 Antibiotics and Antibacterial Agents: Classifications and Structure-Activity Relationship; 3 Epidemiology of Resistance to Antibacterial Agents; 4 Development of an Antibiotic: Microbiology; 5 Penicillins; 6 Cephems for Parenteral Use; 7 Oral Cephalosporins; 8 Carbapenems; 9 Penems; 10 Monocyclic ß-Lactams; 11 ß-Lactam Prodrugs; 12 Peptidoglycan Synthesis Inhibitors; 13 ß-Lactamase Inhibitors. 14 ß-Lactamase Inhibitors under Research15?-Lactams and Derivatives; 16 Aminocyclitol Aminoglycosides; 17 Spectinomycin; 18 Macrolides; 19 Ketolides; 20 Streptogramins; 21 Lincosamines; 22 Oxazolidinones; 23 Fusidic Acid; 24 Tetracyclines; 25 Tetracyclines under Investigation; 26 Fluoroquinolones; 27 DNA Gyrase Inhibitors Other Than Fluoroquinolones; 28 Codrugs; 29 Coumarin Antibiotics: Novobiocin, Coumermycin, and Clorobiocin; 30 Peptide. 14 β-Lactamase Inhibitors under Research15 γ-Lactams and Derivatives; 16 Aminocyclitol Aminoglycosides; 17 Spectinomycin; 18 Macrolides; 19 Ketolides; 20 Streptogramins; 21 Lincosamines; 22 Oxazolidinones; 23 Fusidic Acid; 24 Tetracyclines; 25 Tetracyclines under Investigation; 26 Fluoroquinolones; 27 DNA Gyrase Inhibitors Other Than Fluoroquinolones; 28 Codrugs; 29 Coumarin Antibiotics: Novobiocin, Coumermycin, and Clorobiocin; 30 Peptide Antibiotics; 31 Glycopeptides and Lipoglycopeptides; 32 Ansamycins; 33 Phenicols; 34 5-Nitroimidazoles. Contents; Foreword; Foreword to the First Edition, Revised; Foreword to the First Edition; Preface; Contributors; 1 Historical Review of Antibacterial Chemotherapy; 2 Antibiotics and Antibacterial Agents: Classifications and Structure-Activity Relationship; 3 Epidemiology of Resistance to Antibacterial Agents; 4 Development of an Antibiotic: Microbiology; 5 Penicillins; 6 Cephems for Parenteral Use; 7 Oral Cephalosporins; 8 Carbapenems; 9 Penems; 10 Monocyclic β-Lactams; 11 β-Lactam Prodrugs; 12 Peptidoglycan Synthesis Inhibitors; 13 β-Lactamase Inhibitors. |
| Record Nr. | UNINA-9910555017003321 |
| Washington, District of Columbia : , : John Wiley & Sons, Inc., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Performance characteristics of borate fatty acid formulations as mold inhibitors / / Robert D. Coleman, Vina W. Yang, Carol A. Clausen
| Performance characteristics of borate fatty acid formulations as mold inhibitors / / Robert D. Coleman, Vina W. Yang, Carol A. Clausen |
| Autore | Coleman Robert D. |
| Pubbl/distr/stampa | Madison, WI : , : United States Department of Agriculture, Forest Service, Forest Products Laboratory, , 2013 |
| Descrizione fisica | 1 online resource (6 pages) |
| Collana | Research paper FPL-RP |
| Soggetto topico |
Wood preservatives
Antifungal agents Molds (Fungi) - Control Wood-decaying fungi - Control |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910704657403321 |
|
Coleman Robert D.
|
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| Madison, WI : , : United States Department of Agriculture, Forest Service, Forest Products Laboratory, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Surveillance of antimicrobial consumption in Europe
| Surveillance of antimicrobial consumption in Europe |
| Pubbl/distr/stampa | Stockholm, Sweden : , : European Centre for Disease Prevention and Control, , 2013- |
| Descrizione fisica | 1 online resource |
| Collana | ECDC surveillance report |
| Soggetto topico |
Anti-infective agents - Therapeutic use - Europe
Antibacterial agents - Europe Antifungal agents - Europe Antiviral agents - Europe Drug resistance in microorganisms - Europe Anti-infective agents - Therapeutic use Antibacterial agents Antifungal agents Antiviral agents Drug resistance in microorganisms |
| Soggetto genere / forma | Periodicals. |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Annual report of the European Surveillance of Antimicrobial Consumption Network |
| Record Nr. | UNINA-9910894211203321 |
| Stockholm, Sweden : , : European Centre for Disease Prevention and Control, , 2013- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Antifungal agents
(8)
- Biofilms (3)
- Immunotherapy (3)
- Antibacterial agents (2)
- Fungicides (2)