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Antibiotics : current innovations and future trends / / edited by Sergio Sánchez, Departamento de Biologia Molecular y Biotecnologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico, and Arnold L. Demain, Research Institute for Scientists Emeriti (RISE), Drew University, Madison, NJ, USA
| Antibiotics : current innovations and future trends / / edited by Sergio Sánchez, Departamento de Biologia Molecular y Biotecnologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico, and Arnold L. Demain, Research Institute for Scientists Emeriti (RISE), Drew University, Madison, NJ, USA |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (450 p.) |
| Disciplina | 615.329 |
| Soggetto topico |
Antibiotics industry
Antibiotics Antibiotics - Analysis |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-908230-55-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; 1: What is an Antibiotic?; Introduction; The etymology of the word antibiotic; Disinfectants and related compounds; Chemotherapeutic agents, magic bullets and selective toxicity; The long shadow of Selman Waksman and synthetic antibiotics; Antibiotic resistance and the emergence of 'antibacterial' as a synonym for 'antibiotic'; Selective toxicity, lexicography and the evolving definition of antibiotic; Why worry about definitions?; Summary; 2: Main Applications of Antibiotics; Introduction
Antibiotics for treatment of infectious diseasesFurther discussion; Conclusion and future perspectives; 3: Microorganisms Producing Antibiotics; The antibiotic producers and antibiotic functions; The numbers of antibiotic-producing microbes; Chemical diversity; Biodiversity; The way ahead; Epilogue; 4: The Need for New Antibiotics; The antibiotic crisis; Antibiotic resistance; Emergence of new diseases; Lack of new drugs; Why drug discovery has dropped; Lack of new antibiotics; Natural products versus synthetics as drugs; Possible solutions to the problem; 5: Tackling Antibiotic Resistance IntroductionPreparation of new vaccines against resistant bacterial strains; Search for new antibiotics; Newly approved antibiotics and antibiotics in the pipeline; Search for new antibiotics from non-traditional or less traditional sources; Microbial genome sequences - search for genes specifying biosynthesis of antibiotics; Forgotten antibiotics to be revitalized; New antibiotic targets; Discussion and conclusions; 6: Eradication of Dormant Pathogens; Persisters and infectious disease; Mechanisms of persister formation; Persister eradication; 7: Toxicity of Antibacterial Drugs Class effectsHas genomics been misleading?; Collateral damage; What is 'safe enough'?; Into the future: prophylaxis and precision medicine; Conclusions; 8: Overuse of Antibiotics: Non-medical Applications; Introduction; Antibiotic resistance - evolution and drivers; Problem: overuse of antibiotics in agriculture; Overuse of antibiotics leads to environmental contamination; Antibiotic overuse in international travel and trade; Conclusion; 9: Antibiotics for Emerging and Re-emerging Diseases; Introduction; Antiparasitic antibiotics; Antiviral antibiotics; Anti-pathogenic E. coli antibiotics Conclusions10: Endophytes as a Potential Source of New Antibiotics; Introduction; Endophyte definition; Distribution in the plant; Biological properties; Pharmaceutical importance of endophytes; Endophytes as producers of the same metabolites as the host plant; Antibiotics from endophytic microorganisms; Potential agricultural uses of endophytic secondary metabolites; Volatile organic compounds are potentially important for biocontrol and control of fruit post-harvest diseases; Compounds with antibiotic activity chemically derived from natural endophytic secondary metabolites Current situation and compounds undergoing clinical evaluation |
| Record Nr. | UNINA-9910460088503321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibiotics : current innovations and future trends / / edited by Sergio Sánchez, Departamento de Biologia Molecular y Biotecnologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico, and Arnold L. Demain, Research Institute for Scientists Emeriti (RISE), Drew University, Madison, NJ, USA
| Antibiotics : current innovations and future trends / / edited by Sergio Sánchez, Departamento de Biologia Molecular y Biotecnologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico, and Arnold L. Demain, Research Institute for Scientists Emeriti (RISE), Drew University, Madison, NJ, USA |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (450 p.) |
| Disciplina | 615.329 |
| Soggetto topico |
Antibiotics industry
Antibiotics Antibiotics - Analysis |
| ISBN | 1-908230-55-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; 1: What is an Antibiotic?; Introduction; The etymology of the word antibiotic; Disinfectants and related compounds; Chemotherapeutic agents, magic bullets and selective toxicity; The long shadow of Selman Waksman and synthetic antibiotics; Antibiotic resistance and the emergence of 'antibacterial' as a synonym for 'antibiotic'; Selective toxicity, lexicography and the evolving definition of antibiotic; Why worry about definitions?; Summary; 2: Main Applications of Antibiotics; Introduction
Antibiotics for treatment of infectious diseasesFurther discussion; Conclusion and future perspectives; 3: Microorganisms Producing Antibiotics; The antibiotic producers and antibiotic functions; The numbers of antibiotic-producing microbes; Chemical diversity; Biodiversity; The way ahead; Epilogue; 4: The Need for New Antibiotics; The antibiotic crisis; Antibiotic resistance; Emergence of new diseases; Lack of new drugs; Why drug discovery has dropped; Lack of new antibiotics; Natural products versus synthetics as drugs; Possible solutions to the problem; 5: Tackling Antibiotic Resistance IntroductionPreparation of new vaccines against resistant bacterial strains; Search for new antibiotics; Newly approved antibiotics and antibiotics in the pipeline; Search for new antibiotics from non-traditional or less traditional sources; Microbial genome sequences - search for genes specifying biosynthesis of antibiotics; Forgotten antibiotics to be revitalized; New antibiotic targets; Discussion and conclusions; 6: Eradication of Dormant Pathogens; Persisters and infectious disease; Mechanisms of persister formation; Persister eradication; 7: Toxicity of Antibacterial Drugs Class effectsHas genomics been misleading?; Collateral damage; What is 'safe enough'?; Into the future: prophylaxis and precision medicine; Conclusions; 8: Overuse of Antibiotics: Non-medical Applications; Introduction; Antibiotic resistance - evolution and drivers; Problem: overuse of antibiotics in agriculture; Overuse of antibiotics leads to environmental contamination; Antibiotic overuse in international travel and trade; Conclusion; 9: Antibiotics for Emerging and Re-emerging Diseases; Introduction; Antiparasitic antibiotics; Antiviral antibiotics; Anti-pathogenic E. coli antibiotics Conclusions10: Endophytes as a Potential Source of New Antibiotics; Introduction; Endophyte definition; Distribution in the plant; Biological properties; Pharmaceutical importance of endophytes; Endophytes as producers of the same metabolites as the host plant; Antibiotics from endophytic microorganisms; Potential agricultural uses of endophytic secondary metabolites; Volatile organic compounds are potentially important for biocontrol and control of fruit post-harvest diseases; Compounds with antibiotic activity chemically derived from natural endophytic secondary metabolites Current situation and compounds undergoing clinical evaluation |
| Record Nr. | UNINA-9910787002203321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibiotics : current innovations and future trends / / edited by Sergio Sánchez, Departamento de Biologia Molecular y Biotecnologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico, and Arnold L. Demain, Research Institute for Scientists Emeriti (RISE), Drew University, Madison, NJ, USA
| Antibiotics : current innovations and future trends / / edited by Sergio Sánchez, Departamento de Biologia Molecular y Biotecnologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico, and Arnold L. Demain, Research Institute for Scientists Emeriti (RISE), Drew University, Madison, NJ, USA |
| Pubbl/distr/stampa | Norfolk, England : , : Caister Academic Press, , [2015] |
| Descrizione fisica | 1 online resource (450 p.) |
| Disciplina | 615.329 |
| Soggetto topico |
Antibiotics industry
Antibiotics Antibiotics - Analysis |
| ISBN | 1-908230-55-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Contributors; Current Books of Interest; Preface; 1: What is an Antibiotic?; Introduction; The etymology of the word antibiotic; Disinfectants and related compounds; Chemotherapeutic agents, magic bullets and selective toxicity; The long shadow of Selman Waksman and synthetic antibiotics; Antibiotic resistance and the emergence of 'antibacterial' as a synonym for 'antibiotic'; Selective toxicity, lexicography and the evolving definition of antibiotic; Why worry about definitions?; Summary; 2: Main Applications of Antibiotics; Introduction
Antibiotics for treatment of infectious diseasesFurther discussion; Conclusion and future perspectives; 3: Microorganisms Producing Antibiotics; The antibiotic producers and antibiotic functions; The numbers of antibiotic-producing microbes; Chemical diversity; Biodiversity; The way ahead; Epilogue; 4: The Need for New Antibiotics; The antibiotic crisis; Antibiotic resistance; Emergence of new diseases; Lack of new drugs; Why drug discovery has dropped; Lack of new antibiotics; Natural products versus synthetics as drugs; Possible solutions to the problem; 5: Tackling Antibiotic Resistance IntroductionPreparation of new vaccines against resistant bacterial strains; Search for new antibiotics; Newly approved antibiotics and antibiotics in the pipeline; Search for new antibiotics from non-traditional or less traditional sources; Microbial genome sequences - search for genes specifying biosynthesis of antibiotics; Forgotten antibiotics to be revitalized; New antibiotic targets; Discussion and conclusions; 6: Eradication of Dormant Pathogens; Persisters and infectious disease; Mechanisms of persister formation; Persister eradication; 7: Toxicity of Antibacterial Drugs Class effectsHas genomics been misleading?; Collateral damage; What is 'safe enough'?; Into the future: prophylaxis and precision medicine; Conclusions; 8: Overuse of Antibiotics: Non-medical Applications; Introduction; Antibiotic resistance - evolution and drivers; Problem: overuse of antibiotics in agriculture; Overuse of antibiotics leads to environmental contamination; Antibiotic overuse in international travel and trade; Conclusion; 9: Antibiotics for Emerging and Re-emerging Diseases; Introduction; Antiparasitic antibiotics; Antiviral antibiotics; Anti-pathogenic E. coli antibiotics Conclusions10: Endophytes as a Potential Source of New Antibiotics; Introduction; Endophyte definition; Distribution in the plant; Biological properties; Pharmaceutical importance of endophytes; Endophytes as producers of the same metabolites as the host plant; Antibiotics from endophytic microorganisms; Potential agricultural uses of endophytic secondary metabolites; Volatile organic compounds are potentially important for biocontrol and control of fruit post-harvest diseases; Compounds with antibiotic activity chemically derived from natural endophytic secondary metabolites Current situation and compounds undergoing clinical evaluation |
| Record Nr. | UNINA-9910824528303321 |
| Norfolk, England : , : Caister Academic Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibiotics in laboratory medicine / / Victor Lorian, editor ; Frances Destefano, acquisition editor ; Mike Standen, developmental editor ; Teresa Mallon, designer
| Antibiotics in laboratory medicine / / Victor Lorian, editor ; Frances Destefano, acquisition editor ; Mike Standen, developmental editor ; Teresa Mallon, designer |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2005 |
| Descrizione fisica | 1 online resource (898 p.) |
| Disciplina | 615/.329 |
| Soggetto topico |
Microbial sensitivity tests
Antibiotics - Analysis Drug resistance in microorganisms |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-4698-7419-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910454004803321 |
| Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibiotics in laboratory medicine / / Victor Lorian, editor ; Frances Destefano, acquisition editor ; Mike Standen, developmental editor ; Teresa Mallon, designer
| Antibiotics in laboratory medicine / / Victor Lorian, editor ; Frances Destefano, acquisition editor ; Mike Standen, developmental editor ; Teresa Mallon, designer |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2005 |
| Descrizione fisica | 1 online resource (898 p.) |
| Disciplina | 615/.329 |
| Soggetto topico |
Microbial sensitivity tests
Antibiotics - Analysis Drug resistance in microorganisms |
| ISBN | 1-4698-7419-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The breakpoint / Matthew A. Wikler, Paul G. Ambrose -- Antimicrobial susceptibility on solid media / John D. Turnidge, Jan M. Bell -- Susceptibility testing of antimicrobials in liquid media / Daniel Amsterdam -- Antimicrobial susceptibility testing of anaerobic bacteria / David W. Hecht -- Antimycobacterial agents: in vitro susceptibility testing and mechanisms of action and resistance / Clark B. Inderlied and Kevin A. Nash -- Antifungal drugs: mechanisms of action, drug resistance, susceptibility testing and assays of activity in biological fluids / Michael A. Pfaller, Daniel J. Diekema, and Michael G. Rinaldi -- Antimicrobial susceptibility testing for some atypical microorganisms (chlamydia, mycoplasma, rickettsia, ehrlichia, coxiella, and spirochetes) / Jean-Marc Rolain, Didier Raoult -- Applications, significance of, and methods for the measurement of antimicrobial concentrations in human body fluids / Roger D. Klein and Stephen C. Edberg -- Antimicrobial combinations / Satish K. Pillai, Robert C. Moellering, Jr., and George M. Eliopoulos -- Genetic and biochemical mechanisms of bacterial resistance to antimicrobial agents / Louis B. Rice and Robert A. Bonomo -- Molecular methods for the detection of antibacterial resistance genes / Margareta Ieven -- Molecular mechanisms of action for antimicrobial agents: general principles and mechanisms for selected classes of antibiotics / Charles W. Stratton -- The antivirogram and the modes of action of antiviral agents, HIV, hepatitis, influenza, and cytomegalovirus / Pierre Dellamonica ... [et al.] -- Disinfectants and antiseptics, modes of action, mechanisms of resistance, and testing / Joseph M. Ascenzi, Martin S. Favero -- Evaluation of antimicrobials in experimental animal infections / O' Reilly ... [et al.] -- Extravascular antimicrobial distribution and the respective blood and urine concentrations in humans / David M. Bamberger ... [et al.] -- Epidemiology of antimicrobial resistance: species prevalence, susceptibility profiles, and resistance trends / Thomas R. Fritsche, Helio S. Sader, Ronald N. Jones. |
| Record Nr. | UNINA-9910777733103321 |
| Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antibiotics in laboratory medicine / / Victor Lorian, editor ; Frances Destefano, acquisition editor ; Mike Standen, developmental editor ; Teresa Mallon, designer
| Antibiotics in laboratory medicine / / Victor Lorian, editor ; Frances Destefano, acquisition editor ; Mike Standen, developmental editor ; Teresa Mallon, designer |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2005 |
| Descrizione fisica | 1 online resource (898 p.) |
| Disciplina | 615/.329 |
| Soggetto topico |
Microbial sensitivity tests
Antibiotics - Analysis Drug resistance in microorganisms |
| ISBN | 1-4698-7419-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The breakpoint / Matthew A. Wikler, Paul G. Ambrose -- Antimicrobial susceptibility on solid media / John D. Turnidge, Jan M. Bell -- Susceptibility testing of antimicrobials in liquid media / Daniel Amsterdam -- Antimicrobial susceptibility testing of anaerobic bacteria / David W. Hecht -- Antimycobacterial agents: in vitro susceptibility testing and mechanisms of action and resistance / Clark B. Inderlied and Kevin A. Nash -- Antifungal drugs: mechanisms of action, drug resistance, susceptibility testing and assays of activity in biological fluids / Michael A. Pfaller, Daniel J. Diekema, and Michael G. Rinaldi -- Antimicrobial susceptibility testing for some atypical microorganisms (chlamydia, mycoplasma, rickettsia, ehrlichia, coxiella, and spirochetes) / Jean-Marc Rolain, Didier Raoult -- Applications, significance of, and methods for the measurement of antimicrobial concentrations in human body fluids / Roger D. Klein and Stephen C. Edberg -- Antimicrobial combinations / Satish K. Pillai, Robert C. Moellering, Jr., and George M. Eliopoulos -- Genetic and biochemical mechanisms of bacterial resistance to antimicrobial agents / Louis B. Rice and Robert A. Bonomo -- Molecular methods for the detection of antibacterial resistance genes / Margareta Ieven -- Molecular mechanisms of action for antimicrobial agents: general principles and mechanisms for selected classes of antibiotics / Charles W. Stratton -- The antivirogram and the modes of action of antiviral agents, HIV, hepatitis, influenza, and cytomegalovirus / Pierre Dellamonica ... [et al.] -- Disinfectants and antiseptics, modes of action, mechanisms of resistance, and testing / Joseph M. Ascenzi, Martin S. Favero -- Evaluation of antimicrobials in experimental animal infections / O' Reilly ... [et al.] -- Extravascular antimicrobial distribution and the respective blood and urine concentrations in humans / David M. Bamberger ... [et al.] -- Epidemiology of antimicrobial resistance: species prevalence, susceptibility profiles, and resistance trends / Thomas R. Fritsche, Helio S. Sader, Ronald N. Jones. |
| Record Nr. | UNINA-9910820738603321 |
| Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
