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Active Antimicrobial Food Packaging / / edited by Isıl Var and Sinan Uzunlu
Active Antimicrobial Food Packaging / / edited by Isıl Var and Sinan Uzunlu
Pubbl/distr/stampa London, United Kingdom : , : IntechOpen, , 2019
Descrizione fisica 1 online resource (104 pages) : illustrations some color
Disciplina 664.09
Soggetto topico Anti-infective agents
Food - Packing
ISBN 1-83881-794-8
1-78985-004-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910317767003321
London, United Kingdom : , : IntechOpen, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Advances and Applications of Nano-antimicrobial Treatments / / editors, Mauro Pollini, Alessandro Sannino and Federica Paladini
Advances and Applications of Nano-antimicrobial Treatments / / editors, Mauro Pollini, Alessandro Sannino and Federica Paladini
Pubbl/distr/stampa Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2017
Descrizione fisica 1 online resource (vii, 126 pages)
Disciplina 615.792
Soggetto topico Anti-infective agents
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910673905303321
Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Advances and applications of nano-antimicrobial treatments / / edited by Mauro Pollini, Alessandro Sannino, Federica Paladini
Advances and applications of nano-antimicrobial treatments / / edited by Mauro Pollini, Alessandro Sannino, Federica Paladini
Pubbl/distr/stampa Basel : , : MDPI, , [2017]
Descrizione fisica 1 online resource (vii, 139 pages)
Disciplina 615.792
Soggetto topico Anti-infective agents
ISBN 3-03842-381-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910765787503321
Basel : , : MDPI, , [2017]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
Pubbl/distr/stampa Greenwich, CT ; ; London, England, : Jai Press, 2007
Descrizione fisica 1 online resource (265 p.)
Disciplina 616.9
616.9/25061/05
616.91061
Altri autori (Persone) De ClercqErik
Collana Advances in antiviral drug design
Soggetto topico Antiviral agents
Anti-infective agents
Soggetto genere / forma Electronic books.
ISBN 1-281-11983-0
9786611119836
0-08-054824-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs)
AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index
Record Nr. UNINA-9910457252903321
Greenwich, CT ; ; London, England, : Jai Press, 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
Pubbl/distr/stampa Greenwich, CT ; ; London, England, : Jai Press, 2007
Descrizione fisica 1 online resource (265 p.)
Disciplina 616.9
616.9/25061/05
616.91061
Altri autori (Persone) De ClercqErik
Collana Advances in antiviral drug design
Soggetto topico Antiviral agents
Anti-infective agents
ISBN 1-281-11983-0
9786611119836
0-08-054824-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs)
AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index
Record Nr. UNINA-9910784598503321
Greenwich, CT ; ; London, England, : Jai Press, 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Annals of clinical microbiology and antimicrobials
Annals of clinical microbiology and antimicrobials
Pubbl/distr/stampa London, : BioMed Central, 2002-
Soggetto topico Medical microbiology
Anti-infective agents
Communicable Diseases - drug therapy
Anti-Infective Agents - therapeutic use
Microbiological Techniques
Soggetto genere / forma Periodical
Fulltext
Internet Resources.
Periodicals.
Soggetto non controllato Microbiology & Immunology
ISSN 1476-0711
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti ACMA
Record Nr. UNISA-996212832903316
London, : BioMed Central, 2002-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Annals of clinical microbiology and antimicrobials
Annals of clinical microbiology and antimicrobials
Pubbl/distr/stampa London, : BioMed Central, 2002-
Soggetto topico Medical microbiology
Anti-infective agents
Communicable Diseases - drug therapy
Anti-Infective Agents - therapeutic use
Microbiological Techniques
Medicaments antiinfecciosos
Malalties infeccioses
Microbiologia mèdica
Soggetto genere / forma Periodical
Fulltext
Internet Resources.
Periodicals.
Revistes electròniques.
ISSN 1476-0711
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti ACMA
Record Nr. UNINA-9910147147603321
London, : BioMed Central, 2002-
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Anti-infective agents in medicinal chemistry
Anti-infective agents in medicinal chemistry
Pubbl/distr/stampa Saif Zone, Sharjah, U.A.E. ; ; San Francisco, CA, : Bentham Science Publishers, ©2006-
Descrizione fisica 1 online resource
Soggetto topico Anti-infective agents
Anti-Infective Agents
Anti-Infective Agents - therapeutic use
Soggetto genere / forma Periodicals.
ISSN 1875-6018
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996199302603316
Saif Zone, Sharjah, U.A.E. ; ; San Francisco, CA, : Bentham Science Publishers, ©2006-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Antibiotics : targets, mechanisms and resistance / / edited by Claudio O. Gualerzi [and three others]
Antibiotics : targets, mechanisms and resistance / / edited by Claudio O. Gualerzi [and three others]
Pubbl/distr/stampa Weinheim : , : Wiley-VCH, , 2013
Descrizione fisica 1 online resource (575 p.)
Disciplina 615.329
Altri autori (Persone) GualerziClaudio O. <1942->
Soggetto topico Antibiotics
Anti-infective agents
ISBN 3-527-65970-6
3-527-65968-4
3-527-65971-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright; Contents; Preface; List of Contributors; Chapter 1 A Chemist's Survey of Different Antibiotic Classes; 1.1 Introduction; 1.2 Aminoglycosides; 1.3 β-Lactams; 1.4 Linear Peptides; 1.4.1 Glycopeptides-Dalbaheptides; 1.4.2 Lantibiotics; 1.5 Cyclic Peptides; 1.6 Thiazolylpeptides; 1.7 Macrolactones; 1.7.1 Macrolides; 1.7.2 Difimicin; 1.8 Ansamycins-Rifamycins; 1.9 Tetracyclines; 1.10 Oxazolidinones; 1.11 Lincosamides; 1.12 Pleuromutilins; 1.13 Quinolones; 1.14 Aminocoumarins; References; Chapter 2 Antibacterial Discovery: Problems and Possibilities; 2.1 Introduction
2.2 Why Is Antibacterial Discovery Difficult? The Problems2.3 Target Choice: Essentiality; 2.4 Target Choice: Resistance; 2.5 Cell Entry; 2.6 Screening Strategies; 2.6.1 Empirical Screens; 2.6.2 Phenotypic Whole-Cell Screens; 2.6.3 In Vitro Screens for Single-Target Inhibitors; 2.6.4 Chemicals to Screen; 2.6.4.1 Chemical Collections; 2.7 Natural Products; 2.8 Computational Chemistry, Virtual Screening, Structure- and Fragment-Based Drug Design (SBDD and FBDD); 2.9 Conclusions; References; Chapter 3 Impact of Microbial Natural Products on Antibacterial Drug Discovery; 3.1 Introduction
3.2 Natural Products for Drug Discovery3.3 Microbial Natural Products; 3.4 The Challenge of Finding Novel Antibiotics from New Natural Sources; 3.5 Workflow for Drug Discovery from Microbial Natural Products; 3.6 Antimicrobial Activities: Targets for Screens; 3.7 Natural Products: A Continuing Source for Inspiration; 3.8 Genome Mining in Natural Product Discovery; 3.9 Conclusions; References; Chapter 4 Antibiotics and Resistance: A Fatal Attraction; 4.1 To Be or Not to Be Resistant: Why and How Antibiotic Resistance Mechanisms Develop and Spread among Bacteria
4.1.1 Horizontal and Vertical Transmission of Resistance Genes4.2 Bacterial Resistance to Antibiotics by Enzymatic Degradation or Modification; 4.2.1 Antibiotic Resistance by Hydrolytic Enzymes; 4.2.1.1 Î2-Lactamases; 4.2.1.2 Macrolide Esterases; 4.2.1.3 Epoxidases; 4.2.1.4 Proteases; 4.2.2 Antibiotic Transferases Prevent Target Recognition; 4.2.2.1 Acyltransfer; 4.2.2.2 Phosphotransferases; 4.2.2.3 Nucleotidyltransferases; 4.2.2.4 ADP-Ribosyltransferases; 4.2.2.5 Glycosyltransferases; 4.2.3 Redox Enzymes; 4.3 Antibiotic Target Alteration: The Trick Exists and It Is in the Genetics
4.3.1 Low-Affinity Homologous Genes4.3.1.1 Rifamycin Low-Affinity RpoB; 4.3.1.2 Mutated Genes Conferring Resistance to Quinolone, Fluoroquinolone and Aminocoumarins; 4.3.1.3 PBP2a: A Low-Affinity Penicillin-Binding Protein; 4.3.1.4 Dihydropteroate Synthases Not Inhibited by Sulfonamide; 4.3.2 Chemical Modification of Antibiotic Target; 4.3.2.1 23S rRNA Modification; 4.3.2.2 16S rRNA Modification; 4.3.2.3 Reprogramming Chemical Composition of a Bacterial Cell-Wall Precursor; 4.3.3 Ribosomal Protection and Tetracycline Resistance
4.3.4 Chromosomal Mutations in Genes Required for Membrane Phospholipid Metabolism: Lipopeptide Resistance
Record Nr. UNINA-9910141811203321
Weinheim : , : Wiley-VCH, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antibiotics : targets, mechanisms and resistance / / edited by Claudio O. Gualerzi [and three others]
Antibiotics : targets, mechanisms and resistance / / edited by Claudio O. Gualerzi [and three others]
Edizione [1st ed.]
Pubbl/distr/stampa Weinheim : , : Wiley-VCH, , 2013
Descrizione fisica 1 online resource (575 p.)
Disciplina 615.329
Altri autori (Persone) GualerziClaudio O. <1942->
Soggetto topico Antibiotics
Anti-infective agents
ISBN 3-527-65970-6
3-527-65968-4
3-527-65971-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright; Contents; Preface; List of Contributors; Chapter 1 A Chemist's Survey of Different Antibiotic Classes; 1.1 Introduction; 1.2 Aminoglycosides; 1.3 β-Lactams; 1.4 Linear Peptides; 1.4.1 Glycopeptides-Dalbaheptides; 1.4.2 Lantibiotics; 1.5 Cyclic Peptides; 1.6 Thiazolylpeptides; 1.7 Macrolactones; 1.7.1 Macrolides; 1.7.2 Difimicin; 1.8 Ansamycins-Rifamycins; 1.9 Tetracyclines; 1.10 Oxazolidinones; 1.11 Lincosamides; 1.12 Pleuromutilins; 1.13 Quinolones; 1.14 Aminocoumarins; References; Chapter 2 Antibacterial Discovery: Problems and Possibilities; 2.1 Introduction
2.2 Why Is Antibacterial Discovery Difficult? The Problems2.3 Target Choice: Essentiality; 2.4 Target Choice: Resistance; 2.5 Cell Entry; 2.6 Screening Strategies; 2.6.1 Empirical Screens; 2.6.2 Phenotypic Whole-Cell Screens; 2.6.3 In Vitro Screens for Single-Target Inhibitors; 2.6.4 Chemicals to Screen; 2.6.4.1 Chemical Collections; 2.7 Natural Products; 2.8 Computational Chemistry, Virtual Screening, Structure- and Fragment-Based Drug Design (SBDD and FBDD); 2.9 Conclusions; References; Chapter 3 Impact of Microbial Natural Products on Antibacterial Drug Discovery; 3.1 Introduction
3.2 Natural Products for Drug Discovery3.3 Microbial Natural Products; 3.4 The Challenge of Finding Novel Antibiotics from New Natural Sources; 3.5 Workflow for Drug Discovery from Microbial Natural Products; 3.6 Antimicrobial Activities: Targets for Screens; 3.7 Natural Products: A Continuing Source for Inspiration; 3.8 Genome Mining in Natural Product Discovery; 3.9 Conclusions; References; Chapter 4 Antibiotics and Resistance: A Fatal Attraction; 4.1 To Be or Not to Be Resistant: Why and How Antibiotic Resistance Mechanisms Develop and Spread among Bacteria
4.1.1 Horizontal and Vertical Transmission of Resistance Genes4.2 Bacterial Resistance to Antibiotics by Enzymatic Degradation or Modification; 4.2.1 Antibiotic Resistance by Hydrolytic Enzymes; 4.2.1.1 Î2-Lactamases; 4.2.1.2 Macrolide Esterases; 4.2.1.3 Epoxidases; 4.2.1.4 Proteases; 4.2.2 Antibiotic Transferases Prevent Target Recognition; 4.2.2.1 Acyltransfer; 4.2.2.2 Phosphotransferases; 4.2.2.3 Nucleotidyltransferases; 4.2.2.4 ADP-Ribosyltransferases; 4.2.2.5 Glycosyltransferases; 4.2.3 Redox Enzymes; 4.3 Antibiotic Target Alteration: The Trick Exists and It Is in the Genetics
4.3.1 Low-Affinity Homologous Genes4.3.1.1 Rifamycin Low-Affinity RpoB; 4.3.1.2 Mutated Genes Conferring Resistance to Quinolone, Fluoroquinolone and Aminocoumarins; 4.3.1.3 PBP2a: A Low-Affinity Penicillin-Binding Protein; 4.3.1.4 Dihydropteroate Synthases Not Inhibited by Sulfonamide; 4.3.2 Chemical Modification of Antibiotic Target; 4.3.2.1 23S rRNA Modification; 4.3.2.2 16S rRNA Modification; 4.3.2.3 Reprogramming Chemical Composition of a Bacterial Cell-Wall Precursor; 4.3.3 Ribosomal Protection and Tetracycline Resistance
4.3.4 Chromosomal Mutations in Genes Required for Membrane Phospholipid Metabolism: Lipopeptide Resistance
Record Nr. UNINA-9910822951103321
Weinheim : , : Wiley-VCH, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui