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Pharmacology in Veterinary Anesthesia and Analgesia
| Pharmacology in Veterinary Anesthesia and Analgesia |
| Autore | Aarnes Turi |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2024 |
| Descrizione fisica | 1 online resource (430 pages) |
| Disciplina | 636.089/796 |
| Altri autori (Persone) | LerchePhillip |
| Soggetto topico |
Anesthesia - veterinary
Analgesia - veterinary Anesthetics - pharmacology Anesthetics - adverse effects |
| ISBN |
1-118-97514-6
1-118-97516-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Dedication Page -- Contents -- List of Contributors -- Preface -- Chapter 1 Pharmacokinetics and Pharmacodynamics -- Introduction -- Pharmacokinetics -- Absorption and Bioavailability -- Distribution -- Metabolism (Biotransformation) -- Elimination -- Pharmacokinetic Models -- Pharmacodynamics -- Receptors -- Pharmacokinetic/Pharmacodynamic Modeling -- References -- Further Reading -- Chapter 2 Pharmacogenetics in Veterinary Anesthesia and Analgesia -- Introduction -- Pharmacogenetics - Historical Perspectives -- Pharmacogenetics - Current Situation -- Pharmacogenetics - Cytochrome P450 Function -- Genetic Variations in Drug Disposition -- Pharmacogenomics of Drug Metabolism in Veterinary Patients - Polymorphisms of CYP450 -- Cytochrome P450 1A2 -- Cytochrome P450 2B -- Cytochrome P450 2C -- Cytochrome P450 2D -- Cytochrome P450 2E -- Cytochrome P450 3A -- Other Polymorphisms of Relevance Based upon Clinically Recognized Phenomena - Drug Transporters -- Feline Hypokalemia -- Inherited Ventricular Arrhythmias and Sudden Death of German Shepherd Dogs -- Opioids and Other Polymorphisms -- References -- Chapter 3 Veterinary Regulatory Concerns Associated with Anesthesia and Analgesia for Food Animals -- Introduction -- The Drug Approval Process and Animals -- Extra-Label Drug Use -- The Withdrawal Time, Tolerance and Withdrawal Interval -- Establishment of the Extended Withdrawal Interval -- Anesthetic Drugs - General Characteristics -- Analgesic Drugs -- Precautionary Comments - Euthanasia -- References -- Chapter 4 α2 Receptor Agonists and Antagonists -- Introduction -- α2 Receptors -- Sedative and Analgesic Effects -- Cardiovascular Effects -- Respiratory Effects -- Other Organ Effects -- Contraindications -- Specific α2 Receptor Agonists -- Clonidine -- Xylazine -- Detomidine -- Medetomidine.
Dexmedetomidine -- Romifidine -- α2 Receptor Antagonists -- Yohimbine -- Tolazoline -- Atipamezole -- Vatinoxan -- References -- Chapter 5 Phenothiazines and Butyrophenones -- Mechanism of Action -- Pharmacokinetics of Acepromazine in Major Species (Awake and Under Anesthesia) -- Dogs -- Horses -- Metabolism -- Clinical Use -- Dogs and Cats -- Horses -- Pigs -- Ruminants -- Effect in Patients Under General Anesthesia -- Effects on Organ Systems -- Cardiovascular System -- Respiratory System -- Central Nervous System -- Renal System -- Other Effects -- References -- Chapter 6 Benzodiazepines -- Introduction -- Structures and Mechanisms of Action -- Molecular Structure of Benzodiazepines -- Benzodiazepine Interaction with GABAA Receptors -- Pharmacokinetic Properties -- Routes of Administration -- Protein Binding -- Metabolism -- Excretion -- Indications and Pharmacodynamic Effects -- Hypnotic and Anxiolytic -- Anesthetic Sparing -- Anticonvulsant and Central Nervous System Effects -- Muscle Relaxation -- Amnesic Effects -- Appetite Stimulation -- Side Effects -- Respiratory and Cardiovascular -- Analgesic Effects -- Hepatic Necrosis -- Drug Interaction -- Dependence -- Aging -- Laryngeal Function -- Propylene Glycol -- Pregnancy -- Diazepam Hydrochloride -- Midazolam Maleate -- Lorazepam -- Remimazolam (also Known as CNS 7056) -- Flumazenil -- References -- Chapter 7 Opioid Agonists and Antagonists -- Introduction -- Mechanism of Action -- Pharmacokinetics -- Pharmacodynamics -- Nervous System Effects - Analgesia -- CNS Sedation and Excitation -- Ocular Effects -- Cardiovascular Effects -- Respiratory Effects -- Gastrointestinal Effects -- Urinary Effects -- Integumentary Effects -- Thermoregulatory Effects -- Effect on Inhalant Anesthetic Requirement -- Interactions with Sedatives -- Interactions with Selective Serotonin Reuptake Inhibitors. Opioid Agonists -- Fentanyl Derivatives and Remifentanil -- Opioid Partial Agonist -- Opioid Agonist-Antagonists -- Opioid Antagonists -- References -- Chapter 8 Barbiturates -- Introduction -- Physicochemical Characteristics -- Pharmacokinetics -- Metabolism -- Mechanism of Action -- Pharmacodynamics -- Effects on Cerebral Metabolism -- Effects on Cardiovascular System -- Effects on the Respiratory System -- Other Effects -- Clinical Use in Veterinary Medicine -- Thiopental -- Methohexital -- Pentobarbital Sodium -- References -- Chapter 9 Induction Drugs -- Introduction -- Propofol -- Mechanism of Action -- Pharmacokinetics -- Metabolism -- Clinical Uses -- Effects on Organ Systems -- Cardiovascular -- Respiratory -- Central Nervous System -- Other Effects -- Contraindications -- Drug Interactions -- Alfaxalone -- Mechanism of Action -- Pharmacokinetics -- Metabolism -- Clinical Uses -- Effects on Organ Systems -- Cardiovascular -- Respiratory -- Central Nervous System -- Other Effects -- Contraindications -- Drug Interactions -- Dissociative Anesthetics (Ketamine and Tiletamine) -- Mechanism of Action -- Pharmacokinetics -- Metabolism -- Clinical Uses -- Effects on Organ Systems -- Cardiovascular -- Respiratory -- Central Nervous System -- Other Effects -- Contraindications -- Drug Interactions -- Etomidate -- Mechanism of Action -- Pharmacokinetics -- Metabolism -- Clinical Uses -- Effects on Organ Systems -- Cardiovascular -- Respiratory -- Central Nervous System -- Other Effects -- Contraindications -- Drug Interactions -- Miscellaneous Induction Agents -- Chloral Hydrate -- Alpha-Chloralose -- Urethane -- References -- Chapter 10 Inhalant Anesthetic Agents -- Introduction -- Chemical Structure -- Physical and Chemical Properties of Inhalant Anesthetics -- Mechanism of Action -- Solubility -- Potency -- Pharmacokinetics. Pharmacodynamics of the Volatile Anesthetics -- Nitrous Oxide -- References -- Chapter 11 Non-Steroidal Anti-Inflammatory Drugs -- Introduction -- Pharmacology -- Mechanism of Action -- Classification -- Adverse Effects -- Gastrointestinal -- Kidney -- Coagulation -- Liver -- Interaction with Steroids -- Acetaminophen -- Aspirin -- Carprofen -- Deracoxib -- Etodolac -- Firocoxib -- Flunixin Meglumine -- Grapiprant -- Ketoprofen -- Meloxicam -- Phenylbutazone -- Piroxicam -- Robenacoxib -- References -- Chapter 12 Local Anesthetics -- Pharmacology of Local Anesthetics -- Neural Blockade -- Nerve Classification -- Nerve Blockade -- Other Factors that Influence Local Anesthetic Activity -- Additives -- Site of Injection -- Pregnancy -- Toxicity of Local Anesthetics -- Chemical Structure of Local Anesthetics and Classification of Local Anesthetics -- Ester-Linked Local Anesthetics -- Amide-Linked Local Anesthetics -- Lidocaine -- Mepivacaine -- Ropivacaine -- Bupivacaine -- References -- Chapter 13 Anticholinergics -- Introduction -- Mechanism of Action -- Chemical Structure and Pharmacokinetics -- Atropine -- Glycopyrrolate -- Pharmacodynamics -- Use with Other Drugs -- References -- Chapter 14 CNS Stimulants -- Introduction -- Doxapram -- Metabolism -- Clinical Use -- Methylxanthines -- References -- Chapter 15 Centrally Acting Muscle Relaxants -- Introduction and Physiology -- Guaifenesin -- Benzodiazepines -- Pharmacokinetics - Human -- Metabolism - Humans -- Dog Metabolism -- Diazepam -- Cats -- Diazepam -- Horses - Midazolam -- Alpacas - Midazolam -- Pharmacodynamics -- Reproductive/Nursing Safety -- Drug Interactions -- Veterinary Medicine - Uses and Specific Agents -- Midazolam -- Dosages and Usage -- Dogs -- Cats -- Horses -- Sedation in Neonatal Foals -- Camelids -- Small Ruminants -- Diazepam -- Flumazenil -- References. Chapter 16 Neuromuscular Blocking Agents -- Introduction -- General Concepts and Nomenclature Regarding NMBAs -- Monitoring of Neuromuscular Function -- Depolarizing Neuromuscular Blocking Agents -- Effects on Organ Systems -- Non-depolarizing Neuromuscular Blocking Agents -- Benzylisoquinolines -- Aminosteroids -- Novel Non-depolarizing NMBAs -- References -- Chapter 17 Anticholinesterase Drugs and Reversal of Neuromuscular Blockade -- Introduction -- References -- Chapter 18 Sympathomimetics and Vasopressin -- Introduction -- Mechanism of Action and Main Effects -- Catecholamines - Structure and Pharmacokinetics -- Endogenous Catecholamines -- Epinephrine (Adrenaline) -- Cardiovascular Effects -- During CPR -- Other Effects -- Norepinephrine (Noradrenaline) -- Pharmacodynamics -- Other Effects -- Dopamine -- Pharmacodynamics -- Other Effects -- Synthetic Catecholamines -- Isoproterenol (Isoprenaline) -- Pharmacodynamics -- Dobutamine -- Pharmacodynamics -- Synthetic Non-catecholamines -- Phenylephrine (m-Synephrine, Neosynephrine) -- Pharmacodynamics -- Ephedrine -- Vasopressin (Arginine Vasopressin, Anti-Diuretic Hormone) -- Use in CPR -- Use in Septic Shock -- Selective Beta2 Adrenoceptor Agonists -- Albuterol (Salbutamol) -- Terbutaline -- Drug Interactions -- References -- Chapter 19 Antihypertensives -- Introduction -- Sympatholytic Drugs -- Selective α1-Adrenergic Receptor Antagonists -- Prazosin -- Terazosin and Doxazosin -- Non-Selective α1- and α2-Adrenergic Receptor Antagonists -- Phenoxybenzamine -- Phentolamine -- α2-Adrenergic Receptor Agonists -- Angiotensin Converting Enzyme (ACE) Inhibitors -- Benazepril -- Enalapril -- Angiotensin II Receptor Blockers -- Telmisartan -- Losartan -- Calcium Channel Blocker -- Amlodipine -- β-Adrenergic Receptor Blockers -- Vasodilators -- Others -- Acepromazine -- Magnesium Sulfate -- Diuretics. References. |
| Record Nr. | UNINA-9910877994103321 |
Aarnes Turi
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| Newark : , : John Wiley & Sons, Incorporated, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Veterinary anaesthesia and analgesia
| Veterinary anaesthesia and analgesia |
| Pubbl/distr/stampa | [Oxford, England], : Blackwell Pub., ©2000-2016 |
| Descrizione fisica | 1 online resource |
| Disciplina | 636.089796 |
| Soggetto topico |
Veterinary anesthesia
Anesthesia - veterinary Analgesia - veterinary Anesthetics Anesthesiology Veterinary Medicine Tiermedizin Anästhesie Zeitschrift Online-Ressource Analgésie Anesthésie vétérinaire Animal Soulagement de la douleur |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| ISSN | 1467-2995 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996214091003316 |
| [Oxford, England], : Blackwell Pub., ©2000-2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Veterinary anaesthesia and analgesia
| Veterinary anaesthesia and analgesia |
| Pubbl/distr/stampa | [Oxford, England] : , : Blackwell Pub., , 2000-2016 |
| Descrizione fisica | 1 online resource |
| Disciplina | 636.089796 |
| Soggetto topico |
Veterinary anesthesia
Anesthesia - veterinary Analgesia - veterinary Anesthetics Tiermedizin Anästhesie Zeitschrift Online-Ressource Analgésie Anesthésie vétérinaire Animal Soulagement de la douleur Anesthésie (Médecine vétérinaire) Anesthésiques |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) periodicals. Périodiques. |
| ISSN | 1467-2995 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910227328303321 |
| [Oxford, England] : , : Blackwell Pub., , 2000-2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Veterinary Anesthesia and Analgesia, the 6th Edition of Lumb and Jones
| Veterinary Anesthesia and Analgesia, the 6th Edition of Lumb and Jones |
| Autore | Lamont Leigh |
| Edizione | [6th ed.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2024 |
| Descrizione fisica | 1 online resource (1453 pages) |
| Disciplina | 636.089796 |
| Altri autori (Persone) |
GrimmKurt
RobertsonSheilah LoveLydia SchroederCarrie |
| Soggetto topico |
Anesthesia - veterinary
Analgesia - veterinary |
| ISBN |
1-119-83030-3
1-119-83028-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Dedication -- Contents -- List of Contributors -- Foreword -- Preface -- About the Companion Website -- Section 1 General Topics -- Chapter 1 Overview, History, and Current Issues in Veterinary Anesthesia and Analgesia -- Overview -- Terminology -- History of veterinary anesthesia -- Early milestones -- Conceptualizing depth of anesthesia -- Evolution of veterinary anesthesia as a specialty -- Anesthesiologist defined -- Current issues in veterinary anesthesia and analgesia -- Environmental impact of anesthesia -- Impact of the opioid epidemic on veterinary anesthesia -- Emerging role of technology -- References -- Chapter 2 Anesthetic Risk and Informed Consent -- Assessing anesthetic risk -- Preoperative patient risk assessment -- Morbidity and mortality -- Small animal anesthesia morbidity -- Large animal anesthesia morbidity -- Small animal anesthetic mortality -- Large animal anesthetic mortality -- Informed consent -- References -- Chapter 3 Introduction to Patient Safety -- Introduction -- Nomenclature and terminology -- The risk of harm from healthcare -- Why things go wrong: Human error and the system -- The "process" of anesthesia -- Reason's Swiss cheese model -- Human factors -- Non-technical skills -- Organizational culture -- Blame and no-blame cultures -- Just culture -- Learning culture -- Safety I versus Safety II -- Assessing organizational safety culture -- Data gathering techniques -- Incident reporting systems -- Interviews -- Morbidity and mortality conferences -- Analysis techniques -- Root cause analysis -- Human Factors analysis techniques -- Patient safety evidence in anesthesia -- Patient safety interventions -- Checklists -- Other cognitive aids -- Communication tools: briefings, debriefings, and patient hand-offs -- Simulation-based training -- Engineering solutions.
Methods for reducing medication error -- Assessment of patient safety interventions -- Useful resources -- References -- Chapter 4 Safety Considerations for Laser and Radiographic Procedures and Magnetic Resonance Imaging -- Introduction -- Laser -- Laser beam hazard and safety -- Laser fire hazard and safety -- Anesthetic considerations for laser surgery -- Non-beam hazards and safety -- Radiography -- Ionizing radiation hazards and safety -- Anesthetic considerations for radiography -- Remote facilities -- Magnetic resonance imaging -- Strong static magnetic field -- Gradient magnetic fields -- Radiofrequency fields -- Cryogens -- Anesthetic management considerations -- Sedation versus general anesthesia -- Patient monitoring -- Standing equine MRI -- Gadolinium-based contrast agents -- Emergency procedures -- Personnel considerations -- References -- Chapter 5 Anesthetic Emergencies, Resuscitation, and Adverse Events -- Introduction -- Cardiopulmonary arrest -- Basic life support -- Advanced life support -- Monitoring -- Cardiovascular complications -- Hypotension -- Hemorrhage -- Cardiac dysrhythmias -- Anaphylaxis -- Respiratory complications -- Respiratory depression and apnea -- Hypoxemia -- Airway obstruction -- Bronchospasm -- Accidental extubation -- Iatrogenic tracheal injury -- Acute or undiagnosed pneumothorax -- Pulmonary aspiration -- Volutrauma and barotrauma -- Wooden chest syndrome -- Airway fire -- Anesthetic drug-related complications -- Medical error resulting in overdose -- Patient arousal -- Anesthetic equipment-related complications -- Adjustable pressure-limiting valve closure or malfunction -- Oxygen supply failure -- Breathing system malfunction -- Vaporizer-related complications -- Other complications -- Gastroesophageal reflux and regurgitation -- Ruminal tympany -- Cerebral herniation -- Hyperkalemia. Hypo- or hyperthermia -- Myoclonus -- Postanesthetic complications -- Personnel injury -- Post-critical event debriefing -- References -- Chapter 6 Anesthesia Equipment -- Introduction -- Safety and design -- Introduction to airway management and support equipment -- Endotracheal tubes, lung isolation devices, supraglottic airway devices, laryngoscopes, intubation aids, and techniques -- Endotracheal tubes -- Endotracheal tubes for isolating one lung -- Supraglottic airway devices -- Laryngoscopes -- Intubation aids and techniques -- Nasotracheal intubation -- Wire- or tube-guided techniques -- Endoscope-guided technique -- Endotracheal tube exchangers -- Retrograde intubation -- Tracheostomy -- Lateral pharyngotomy -- Techniques of oxygen administration -- Mask delivery -- Nasal insufflation -- Tracheal insufflation -- Oxygen cages -- Oxygen toxicity -- Introduction anesthetic machines and breathing circuits -- Medical gas supply -- Medical gas safety -- Pressure-reducing valve (regulator) -- Pressure gauges -- The modern anesthetic machine -- Gas flow within the anesthetic machine -- Flowmeters -- Vaporizers -- Descriptions of vaporizers common in veterinary medicine -- Maintenance of vaporizers -- Use of the wrong anesthetic in an agent-specific vaporizer -- Oxygen flush valve -- Common gas outlet -- Breathing systems -- Rebreathing (circle) system -- Non-rebreathing systems -- Waste gas scavenge system -- Routine anesthesia machine checkout procedure -- Anesthesia ventilators -- Classification -- Introduction to single- and dual-circuit ventilators -- Single-circuit piston-driven ventilators -- Single-circuit compressed gas-powered ventilators -- Dual-circuit ventilators -- Control of ventilator driving gas -- Factors that affect delivered tidal volume -- Alarms -- Proper ventilator setup and monitoring -- Selected ventilator models. Respiratory assist devices -- Manual resuscitators -- Demand valves -- Acknowledgment -- References -- Chapter 7 Infection Prevention and Control in Anesthesia -- Introduction -- Postoperative infections -- Infection control and prevention -- Important tools and steps for perianesthetic infection control -- Perioperative checklists -- Hand hygiene -- Attire -- Reprocessing of anesthetic and surgical equipment -- Laryngoscopes and mouth rinse plungers -- Endotracheal tubes -- Monitoring equipment -- Intravenous catheters -- Breathing circuits and ventilators -- Preparation of the surgical site and maintenance of the sterile field -- Risk factors associated with postoperative infections -- Patient-specific risk factors -- Iatrogenic factors -- Environmental factors -- Patient care and drug administration considerations -- Bandages and dressings -- Lubricants -- Anesthetics and analgesics -- References -- Chapter 8 Euthanasia and Humane Killing -- Introduction -- Terminology -- Euthanasia -- Humane slaughter -- Depopulation -- Pain and consciousness -- Mechanisms of action -- Evaluating animal distress -- Choice of killing method relative to onset of unconsciousness -- Fetal sentience and euthanasia -- Low atmospheric pressure stunning -- Foam depopulation -- Agent purity and euthanasia -- Euthanasia in the clinical setting -- References -- Section 2 Patient Monitoring -- Chapter 9 Biomedical Engineering -- Introduction -- History of biomedical engineering -- Subdisciplines of biomedical engineering -- Biomedical instrumentation systems -- Biomedical data -- Biomedical data and time series analysis -- Biomedical engineering milestones in anesthesia -- Stethoscopes -- Endotracheal tubes, laryngoscopes, and inhalant anesthetic delivery -- Anesthetic conserving device -- Pulse oximetry -- Evolution of monitoring equipment and guidelines. Contemporary biomedical engineering applications in anesthesia -- Drug delivery systems -- Ultrasound-guided nerve blocks -- Models and simulators in anesthesia -- Biomedical engineering in veterinary medicine -- References -- Chapter 10 Anesthetic Depth Monitoring and Electroencephalography -- Introduction -- Minimum alveolar concentration -- Physical signs of anesthetic depth -- Stage 1 -- Stage 2 -- Stage 3 -- Stage 4 -- Electrophysiologic monitoring -- Depth-of-anesthesia devices -- The Bispectral Index™ -- Spectral entropy -- Patient state index -- Cerebral state monitor -- Narcotrend® index -- Index of consciousness -- Auditory evoked potentials -- Clinical utility of depth-of-anesthesia devices -- References -- Chapter 11 Electrocardiography -- Introduction -- Electrical potentials and the lead system -- Einthoven's triangle -- Bipolar, unipolar, and precordial leads -- The ECG complex -- Evaluating an ECG -- Heart rate calculation -- Rhythm evaluation -- Mean electrical axis -- Species-specific variations -- Canine -- Feline -- Equine -- ECG equipment -- Artifacts and filters -- Effect of anesthesia -- References -- Chapter 12 Blood Pressure Monitoring -- Introduction -- Blood pressure determinants and definitions -- Mean arterial pressure -- Normal ranges of blood pressure -- Autoregulation of blood pressure -- Invasive blood pressure measurement -- Components for invasive blood pressure measurement -- Physics of invasive blood pressure monitoring systems -- Arterial catheter placement and maintenance -- Non-invasive blood pressure measurement -- Doppler ultrasonographic blood pressure measurement -- Oscillometric blood pressure measurement -- High-definition oscillometric blood pressure measurement -- Central venous pressure measurement -- Indices of fluid responsiveness -- Pulse pressure variation and systolic pressure variation. Plethysmography variability index. |
| Record Nr. | UNINA-9910877375803321 |
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Lamont Leigh
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| Newark : , : John Wiley & Sons, Incorporated, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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