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Adenovirus infection : global status / / Stephen Berger, MD ; cover design by GIDEON Informatics, Inc
| Adenovirus infection : global status / / Stephen Berger, MD ; cover design by GIDEON Informatics, Inc |
| Autore | Berger Stephen |
| Edizione | [2017 edition.] |
| Pubbl/distr/stampa | Los Angeles, California : , : GIDEON Informatics, Inc., , 2017 |
| Descrizione fisica | 1 online resource (80 pages) : color illustrations, tables |
| Disciplina | 576.64 |
| Collana | Gideon E-Book Series |
| Soggetto topico |
Adenoviruses
Molecular biology |
| ISBN | 1-4988-1508-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910164217503321 |
Berger Stephen
|
||
| Los Angeles, California : , : GIDEON Informatics, Inc., , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
| Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910144734503321 |
|
Doerfler Walter <1933->
|
||
| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
| Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910830019203321 |
|
Doerfler Walter <1933->
|
||
| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foreign DNA in mammalian systems / / Walter Doerfler
| Foreign DNA in mammalian systems / / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910876774203321 |
|
Doerfler Walter <1933->
|
||
| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
GIDEON guide to vaccines / / Stephen Berger
| GIDEON guide to vaccines / / Stephen Berger |
| Autore | Berger Stephen |
| Edizione | [2017 edition.] |
| Pubbl/distr/stampa | Los Angeles, California : , : GIDEON Informatics, Inc, , 2017 |
| Descrizione fisica | 1 online resource (222 pages) : color illustrations, tables |
| Disciplina | 615.372 |
| Collana | Gideon E-Book Series |
| Soggetto topico |
Vaccines
Vaccination Adenoviruses |
| ISBN | 1-4988-1278-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910164198703321 |
|
Berger Stephen
|
||
| Los Angeles, California : , : GIDEON Informatics, Inc, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human adenoviruses : from villains to vectors / / Jane Flint, Glen Nemerow
| Human adenoviruses : from villains to vectors / / Jane Flint, Glen Nemerow |
| Autore | Flint S. Jane |
| Pubbl/distr/stampa | New Jersey : , : World Scientific, , [2017] |
| Descrizione fisica | 1 online resource (416 pages) : illustrations (some color) |
| Disciplina | 579.2/443 |
| Soggetto topico | Adenoviruses |
| ISBN | 981-310-980-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | A short history of adenovirus -- Adenovirus composition, structure, and biophysical properties -- Cell attachment and entry -- Intracellular trafficking -- Gene expression -- Replication of the genome -- Capsid assembly, maturation, and egress -- Pathogenesis -- Host defenses -- Antiviral approaches -- Therapeutic applications : history and use of replication-defective vectors -- Therapeutic applications : vaccines and oncolytic vectors. |
| Record Nr. | UNINA-9910163094003321 |
|
Flint S. Jane
|
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| New Jersey : , : World Scientific, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Therapeutic applications of adenoviruses / / edited by Philip Ng and Nicola Brunetti-Pierri
| Therapeutic applications of adenoviruses / / edited by Philip Ng and Nicola Brunetti-Pierri |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, Taylor & Francis, , [2017] |
| Descrizione fisica | 1 online resource (257 pages) : illustrations, tables |
| Disciplina | 616.92507 |
| Collana | Gene and Cell Therapy |
| Soggetto topico | Adenoviruses |
| ISBN |
1-315-35180-3
1-315-36883-8 1-4987-4549-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Adenovirus biology and development as a gene delivery vector / Leslie A. Nash and Robin J. Parks -- Chapter 2. Innate and adaptive immune responses to adenovirus / Svetlana Atasheva and Dmitry M. Shayakhmetov -- Chapter 3. Helper-dependent adenoviral vectors for cell and gene therapy / Nicola Brunetti-Pierri and Philip Ng -- Chapter 4. Chemical and combined genetic and chemical modifications of adenovirus vector capsids to overcome barriers for in vivo vector delivery / Florian Kreppel -- Chapter 5. Design and applications of adenovirus-based hybrid vectors / Anja Ehrhardt and Wenli Zhang -- Chapter 6. Adenovirus vectors for genome editing involving engineered endonucleases / Kamola Saydaminova, Maximilian Richter, Philip Ng, Anja Ehrhardt, Andr Lieber -- Chapter 7. Adenoviruses for vaccination / Michael A. Barry -- Chapter 8. Use of oncolytic adenoviruses for cancer therapy / Cristian Capasso, Manlio Fusciello, Erkko Yl'sm�ki, Vincenzo Cerullo. |
| Record Nr. | UNINA-9910155108503321 |
| Boca Raton : , : CRC Press, Taylor & Francis, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Adenoviruses
(7)
- DNA (3)
- DNA - Methylation (3)
- Genetic transformation (3)
- Mammals - Genetics (3)