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MARC Lista (tabellare)
Biomedical applications and toxicology of carbon nanomaterials / / edited by Chunying Chen and Haifang Wang
Biomedical applications and toxicology of carbon nanomaterials / / edited by Chunying Chen and Haifang Wang
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Descrizione fisica 1 online resource (671 p.)
Soggetto topico Nanostructured materials
Biomedical materials
ISBN 3-527-69287-8
3-527-69285-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Related Titles; Title Page; Copyright; Table of Contents; List of Contributors; Preface; Chapter 1: Synthesis, Functionalization, and Characterization; 1.1 Introduction; 1.2 Fullerenes and Metallofullerenes; 1.3 Carbon Nanotubes; 1.4 Graphene; 1.5 Summary and Outlook; References; Chapter 2: Identification and Detection of Carbon Nanomaterials in Biological Systems; 2.1 Introduction; 2.2 Available Techniques for Qualitative and Quantitative Determination; 2.3 Summary and Outlook; Acknowledgments; References; Chapter 3: Biodistribution and Pharmacokinetics of Carbon Nanomaterials In Vivo
3.1 Introduction3.2 Amorphous Carbon Nanoparticles; 3.3 sp2 Carbon Nanomaterials; 3.4 Nanodiamonds; 3.5 Summary and Outlook; Acknowledgments; References; Chapter 4: Interaction of Carbon Nanomaterials and Components in Biological Systems; 4.1 Introduction; 4.2 Factors Affecting Interaction; 4.3 Interaction of Carbon Nanomaterials with Various Components in Biological Systems; 4.4 Conclusion and Perspectives; References; Chapter 5: Biomedical Applications of Carbon Nanomaterials; 5.1 Introduction; 5.2 Biomedical Applications of Fullerenes; 5.3 Biomedical Applications of Carbon Nanotubes
5.4 Biomedical Applications of Graphene5.5 Conclusion and Perspectives; Acknowledgments; References; Chapter 6: Pulmonary Effects of Carbon Nanomaterials; 6.1 Introduction; 6.2 Physicochemical Properties of Carbon Nanomaterials; 6.3 Fate of Pulmonary Exposed Carbon Nanoparticles (Deposition, Distribution, Translocation, and Clearance); 6.4 Carbon Nanomaterial-Induced Lung Responses; 6.5 Summary; Disclaimer; References; Chapter 7: Cardiovascular and Hemostatic Effects of Carbon Nanomaterials; 7.1 Background; 7.2 Carbon Nanotubes; 7.3 Fullerenes; 7.4 Graphene-Related Nanomaterials
7.5 Conclusions and OutlookAcknowledgments; References; Chapter 8: Modulation of the Immune System by Fullerene and Graphene Derivatives; 8.1 Introduction; 8.2 The Immunological Effects of Fullerene and Its Derivatives; 8.3 Immunological Effects of Graphene and Its Derivatives; 8.4 Perspectives and Outlook; References; Chapter 9: Neuro-, Hepato-, and Nephrotoxicity of Carbon-based Nanomaterials; 9.1 Carbon-based Nanomaterials: Introduction; 9.2 Neurotoxicity of Carbon-based Nanomaterials; 9.3 Hepato and Nephrotoxicity of Carbon-based Nanomaterials
9.4 Points of Consideration for Toxicity Evaluation of Carbon-based Nanomaterials9.5 Summary; Acknowledgments; References; Chapter 10: Genotoxicity and Carcinogenic Potential of Carbon Nanomaterials; 10.1 Introduction; 10.2 Carbon Nanomaterials: Genotoxicity and Carcinogenic Potential; 10.3 Future Challenges in Carbon Nanomaterial Carcinogenesis Risk Assessment; 10.4 Assessment of ECNM-Induced Genotoxicity and Carcinogenesis; 10.5 Concluding Remarks; Acknowledgments; Disclaimer; References; Chapter 11: Effect on Reproductive System of Carbon Nanomaterials; 11.1 Introduction
11.2 Effects of Carbon Nanomaterials on the Reproductive System
Record Nr. UNINA-9910136779203321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Biomedical applications and toxicology of carbon nanomaterials / / edited by Chunying Chen and Haifang Wang
Biomedical applications and toxicology of carbon nanomaterials / / edited by Chunying Chen and Haifang Wang
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Descrizione fisica 1 online resource (671 p.)
Soggetto topico Nanostructured materials
Biomedical materials
ISBN 3-527-69287-8
3-527-69285-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Related Titles; Title Page; Copyright; Table of Contents; List of Contributors; Preface; Chapter 1: Synthesis, Functionalization, and Characterization; 1.1 Introduction; 1.2 Fullerenes and Metallofullerenes; 1.3 Carbon Nanotubes; 1.4 Graphene; 1.5 Summary and Outlook; References; Chapter 2: Identification and Detection of Carbon Nanomaterials in Biological Systems; 2.1 Introduction; 2.2 Available Techniques for Qualitative and Quantitative Determination; 2.3 Summary and Outlook; Acknowledgments; References; Chapter 3: Biodistribution and Pharmacokinetics of Carbon Nanomaterials In Vivo
3.1 Introduction3.2 Amorphous Carbon Nanoparticles; 3.3 sp2 Carbon Nanomaterials; 3.4 Nanodiamonds; 3.5 Summary and Outlook; Acknowledgments; References; Chapter 4: Interaction of Carbon Nanomaterials and Components in Biological Systems; 4.1 Introduction; 4.2 Factors Affecting Interaction; 4.3 Interaction of Carbon Nanomaterials with Various Components in Biological Systems; 4.4 Conclusion and Perspectives; References; Chapter 5: Biomedical Applications of Carbon Nanomaterials; 5.1 Introduction; 5.2 Biomedical Applications of Fullerenes; 5.3 Biomedical Applications of Carbon Nanotubes
5.4 Biomedical Applications of Graphene5.5 Conclusion and Perspectives; Acknowledgments; References; Chapter 6: Pulmonary Effects of Carbon Nanomaterials; 6.1 Introduction; 6.2 Physicochemical Properties of Carbon Nanomaterials; 6.3 Fate of Pulmonary Exposed Carbon Nanoparticles (Deposition, Distribution, Translocation, and Clearance); 6.4 Carbon Nanomaterial-Induced Lung Responses; 6.5 Summary; Disclaimer; References; Chapter 7: Cardiovascular and Hemostatic Effects of Carbon Nanomaterials; 7.1 Background; 7.2 Carbon Nanotubes; 7.3 Fullerenes; 7.4 Graphene-Related Nanomaterials
7.5 Conclusions and OutlookAcknowledgments; References; Chapter 8: Modulation of the Immune System by Fullerene and Graphene Derivatives; 8.1 Introduction; 8.2 The Immunological Effects of Fullerene and Its Derivatives; 8.3 Immunological Effects of Graphene and Its Derivatives; 8.4 Perspectives and Outlook; References; Chapter 9: Neuro-, Hepato-, and Nephrotoxicity of Carbon-based Nanomaterials; 9.1 Carbon-based Nanomaterials: Introduction; 9.2 Neurotoxicity of Carbon-based Nanomaterials; 9.3 Hepato and Nephrotoxicity of Carbon-based Nanomaterials
9.4 Points of Consideration for Toxicity Evaluation of Carbon-based Nanomaterials9.5 Summary; Acknowledgments; References; Chapter 10: Genotoxicity and Carcinogenic Potential of Carbon Nanomaterials; 10.1 Introduction; 10.2 Carbon Nanomaterials: Genotoxicity and Carcinogenic Potential; 10.3 Future Challenges in Carbon Nanomaterial Carcinogenesis Risk Assessment; 10.4 Assessment of ECNM-Induced Genotoxicity and Carcinogenesis; 10.5 Concluding Remarks; Acknowledgments; Disclaimer; References; Chapter 11: Effect on Reproductive System of Carbon Nanomaterials; 11.1 Introduction
11.2 Effects of Carbon Nanomaterials on the Reproductive System
Record Nr. UNINA-9910830271103321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius
Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Descrizione fisica 1 online resource (603 p.)
Soggetto topico Bioreactors - Design and construction
ISBN 3-527-68338-0
1-5231-1519-X
3-527-68336-4
3-527-68337-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright; Table of Contents; Preface; List of Contributors; Chapter 1: Challenges for Bioreactor Design and Operation; 1.1 Introduction; 1.2 Biotechnology Milestones with Implications on Bioreactor Design; 1.3 General Features of Bioreactor Design; 1.4 Recent Trends in Designing and Operating Bioreactors; 1.5 The Systems Biology Approach; 1.6 Using Conceptual Design Methodology; 1.7 An Outlook on Challenges for Bioreactor Design and Operation; References; Chapter 2: Design and Operation of Microbioreactor Systems for Screening and Process Development; 2.1 Introduction
2.2 Key Engineering Parameters and Properties in Microbioreactor Design and Operation2.3 Design of Novel Stirred and Bubble Aerated Microbioreactors; 2.4 Robotics for Microbioreactors; 2.5 Fed-Batch and Continuous Operation of Microbioreactors; 2.6 Monitoring and Control of Microbioreactors; 2.7 Conclusion; References; Chapter 3: Bioreactors on a Chip; 3.1 Introduction; 3.2 Advantages of Microsystems; 3.3 Scaling Down the Bioreactor to the Microfluidic Format; 3.4 Microfabrication Methods for Bioreactors-On-A-Chip; 3.5 Fabrication Materials
3.6 Integrated Sensors for Key Bioreactor Parameters3.7 Model Organisms Applied to BRoCs; 3.8 Applications of Microfluidic Bioreactor Chip; 3.9 Scale Up; 3.10 Conclusion; References; Chapter 4: Scalable Manufacture for Cell Therapy Needs; 4.1 Introduction; 4.2 Requirements for Cell Therapy; 4.3 Stem Cell Types and Products; 4.4 Paradigms in Cell Therapy Manufacture; 4.5 Cell Therapy Manufacturing Platforms; 4.6 Microcarriers and Stirred-Tank Bioreactors; 4.7 Future Trends for Microcarrier Culture; 4.8 Preservation of Cell Therapy Products; 4.9 Conclusions; References
Chapter 5: Artificial Liver Bioreactor Design5.1 Need for Innovative Liver Therapies; 5.2 Requirements to Liver Support Systems; 5.3 Bioreactor Technologies Used in Clinical Trials; 5.4 Optimization of Bioartificial Liver Bioreactor Designs; 5.5 Improvement of Cell Biology in Bioartificial Livers; 5.6 Bioreactors Enabling Cell Production for Transplantation; 5.7 Cell Sources for Bioartificial Liver Bioreactors; 5.8 Outlook; References; Chapter 6: Bioreactors for Expansion of Pluripotent Stem Cells and Their Differentiation to Cardiac Cells; 6.1 Introduction
6.2 Culture Technologies for Pluripotent Stem Cell Expansion6.3 3D Suspension Culture; 6.4 Autologous Versus Allogeneic Cell Therapies: Practical and Economic Considerations for hPSC Processing; 6.5 Upscaling hPSC Cardiomyogenic Differentiation in Bioreactors; 6.6 Conclusion; References; Chapter 7: Culturing Entrapped Stem Cells in Continuous Bioreactors; 7.1 Introduction; 7.2 Materials Used in Stem Cell Entrapment; 7.3 Synthetic Materials; 7.4 Natural Materials; 7.5 Manufacturing and Regulatory Constraints; 7.6 Mass Transfer in the Entrapment Material
7.7 Continuous Bioreactors for Entrapped Stem Cell Culture
Record Nr. UNINA-9910136413703321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius
Bioreactors : design, operation and novel applications / / edited by Carl-Fredrik Mandenius
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Descrizione fisica 1 online resource (603 p.)
Soggetto topico Bioreactors - Design and construction
ISBN 3-527-68338-0
1-5231-1519-X
3-527-68336-4
3-527-68337-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright; Table of Contents; Preface; List of Contributors; Chapter 1: Challenges for Bioreactor Design and Operation; 1.1 Introduction; 1.2 Biotechnology Milestones with Implications on Bioreactor Design; 1.3 General Features of Bioreactor Design; 1.4 Recent Trends in Designing and Operating Bioreactors; 1.5 The Systems Biology Approach; 1.6 Using Conceptual Design Methodology; 1.7 An Outlook on Challenges for Bioreactor Design and Operation; References; Chapter 2: Design and Operation of Microbioreactor Systems for Screening and Process Development; 2.1 Introduction
2.2 Key Engineering Parameters and Properties in Microbioreactor Design and Operation2.3 Design of Novel Stirred and Bubble Aerated Microbioreactors; 2.4 Robotics for Microbioreactors; 2.5 Fed-Batch and Continuous Operation of Microbioreactors; 2.6 Monitoring and Control of Microbioreactors; 2.7 Conclusion; References; Chapter 3: Bioreactors on a Chip; 3.1 Introduction; 3.2 Advantages of Microsystems; 3.3 Scaling Down the Bioreactor to the Microfluidic Format; 3.4 Microfabrication Methods for Bioreactors-On-A-Chip; 3.5 Fabrication Materials
3.6 Integrated Sensors for Key Bioreactor Parameters3.7 Model Organisms Applied to BRoCs; 3.8 Applications of Microfluidic Bioreactor Chip; 3.9 Scale Up; 3.10 Conclusion; References; Chapter 4: Scalable Manufacture for Cell Therapy Needs; 4.1 Introduction; 4.2 Requirements for Cell Therapy; 4.3 Stem Cell Types and Products; 4.4 Paradigms in Cell Therapy Manufacture; 4.5 Cell Therapy Manufacturing Platforms; 4.6 Microcarriers and Stirred-Tank Bioreactors; 4.7 Future Trends for Microcarrier Culture; 4.8 Preservation of Cell Therapy Products; 4.9 Conclusions; References
Chapter 5: Artificial Liver Bioreactor Design5.1 Need for Innovative Liver Therapies; 5.2 Requirements to Liver Support Systems; 5.3 Bioreactor Technologies Used in Clinical Trials; 5.4 Optimization of Bioartificial Liver Bioreactor Designs; 5.5 Improvement of Cell Biology in Bioartificial Livers; 5.6 Bioreactors Enabling Cell Production for Transplantation; 5.7 Cell Sources for Bioartificial Liver Bioreactors; 5.8 Outlook; References; Chapter 6: Bioreactors for Expansion of Pluripotent Stem Cells and Their Differentiation to Cardiac Cells; 6.1 Introduction
6.2 Culture Technologies for Pluripotent Stem Cell Expansion6.3 3D Suspension Culture; 6.4 Autologous Versus Allogeneic Cell Therapies: Practical and Economic Considerations for hPSC Processing; 6.5 Upscaling hPSC Cardiomyogenic Differentiation in Bioreactors; 6.6 Conclusion; References; Chapter 7: Culturing Entrapped Stem Cells in Continuous Bioreactors; 7.1 Introduction; 7.2 Materials Used in Stem Cell Entrapment; 7.3 Synthetic Materials; 7.4 Natural Materials; 7.5 Manufacturing and Regulatory Constraints; 7.6 Mass Transfer in the Entrapment Material
7.7 Continuous Bioreactors for Entrapped Stem Cell Culture
Record Nr. UNINA-9910816353403321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Crystal plasticity finite element methods in materials science and engineering / / Franz Roters [and three others]
Crystal plasticity finite element methods in materials science and engineering / / Franz Roters [and three others]
Autore Roters Franz
Pubbl/distr/stampa Weinheim : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2010]
Descrizione fisica 1 online resource (211 p.)
Disciplina 620.11233015118
Soggetto topico Crystals - Plastic properties
Anisotropy
Finite element method
ISBN 1-282-77491-3
9786612774911
3-527-64209-9
3-527-63148-8
3-527-63149-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Crystal Plasticity Finite Element Methods; Notation; Contents; Preface; 1 Introduction to Crystalline Anisotropy and the Crystal Plasticity Finite Element Method; Part One Fundamentals; 2 Metallurgical Fundamentals of Plastic Deformation; 3 Continuum Mechanics; 4 The Finite Element Method; 5 The Crystal Plasticity Finite Element Method as a Multiphysics Framework; Part Two The Crystal Plasticity Finite Element Method; 6 Constitutive Models; 7 Homogenization; 8 Numerical Aspects of Crystal Plasticity Finite Element Method Implementations; Part Three Application
9 Microscopic and Mesoscopic Examples10 Macroscopic Examples; 11 Outlook and Conclusions; References; Index
Record Nr. UNINA-9910140806803321
Roters Franz  
Weinheim : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2010]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Crystal plasticity finite element methods in materials science and engineering / / Franz Roters [and three others]
Crystal plasticity finite element methods in materials science and engineering / / Franz Roters [and three others]
Autore Roters Franz
Pubbl/distr/stampa Weinheim : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2010]
Descrizione fisica 1 online resource (211 p.)
Disciplina 620.11233015118
Soggetto topico Crystals - Plastic properties
Anisotropy
Finite element method
ISBN 1-282-77491-3
9786612774911
3-527-64209-9
3-527-63148-8
3-527-63149-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Crystal Plasticity Finite Element Methods; Notation; Contents; Preface; 1 Introduction to Crystalline Anisotropy and the Crystal Plasticity Finite Element Method; Part One Fundamentals; 2 Metallurgical Fundamentals of Plastic Deformation; 3 Continuum Mechanics; 4 The Finite Element Method; 5 The Crystal Plasticity Finite Element Method as a Multiphysics Framework; Part Two The Crystal Plasticity Finite Element Method; 6 Constitutive Models; 7 Homogenization; 8 Numerical Aspects of Crystal Plasticity Finite Element Method Implementations; Part Three Application
9 Microscopic and Mesoscopic Examples10 Macroscopic Examples; 11 Outlook and Conclusions; References; Index
Record Nr. UNINA-9910829891803321
Roters Franz  
Weinheim : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2010]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Disordered pharmaceutical materials / / edited by Marc Descamps
Disordered pharmaceutical materials / / edited by Marc Descamps
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Descrizione fisica 1 online resource (646 p.)
Soggetto topico Materials biomèdics
Biotecnologia farmacèutica
Pharmaceutical biotechnology
Biomedical materials
ISBN 3-527-65269-8
3-527-65272-8
3-527-65271-X
9783527652693
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright; Table of Contents; List of Contributors; Chapter 1: Some Facets of Molecular Disorder in Crystalline and Amorphous Pharmaceuticals; 1.1 The Crystal/Amorph Alternative; 1.2 Characteristics of the Disorder in Glass Formers; Acknowledgments; References; Chapter 2: Influence of Disorder on Dissolution; 2.1 Introduction; 2.2 Approaches to Enhance Solubility; 2.3 Measuring the Solubility Advantage of Amorphous Compounds; 2.4 Solid Dispersions; 2.5 Polymer Properties; 2.6 Drug-Polymer Interactions; 2.7 Polymer Concentration; 2.8 Other Formulation Components
2.9 Formulation Variables2.10 Reliable Measurement of Supersaturation; 2.11 Conclusion; References; Chapter 3: Crystal Imperfections in Molecular Crystals: Physical and Chemical Consequences; 3.1 Introduction; 3.2 General Aspects of Defects in Crystals; 3.3 Role of Imperfections in Reactivity and Stability - Chemistry in the Perfect and Imperfect Lattice; 3.4 Role in Physical Processes; 3.5 Concluding Remarks; References; Chapter 4: Observation and Characterization of Crystal Defects in Pharmaceutical Solids; 4.1 Introduction; 4.2 Techniques for Characterizing Defects within Crystals
4.3 Techniques for Characterizing Defects Emergent at Crystal Surfaces4.4 Techniques for Quantifying Defect Densities within Crystals; 4.5 The Complementarity of Techniques for Characterizing Defects; 4.6 Summary and Outlook; Acknowledgment; References; Chapter 5: "Enantiomeric Disorder" Pharmaceutically Oriented; 5.1 Introduction; 5.2 Introduction and Lexicon of Specific Terms Used among Chiral Molecules and Chiral Molecular Associations; 5.3 Restrictions in Symmetry Operations Inside Crystal Lattices with an Enantiomeric Excess Different from Zero
5.4 Impact of Chirality on Phase Diagrams and the Gibbs-Scott Phase Rule5.5 Competitions between Solid Solutions (Impact of Polymorphism on Solid Solutions) Application: Preferential Enrichment; 5.6 Disorder at Level 3 Multiepitaxy between Enantiomers; 5.7 Conclusion and Perspectives; Acknowledgments; References; Chapter 6: Conformational Disorder and Atropisomerism in Pharmaceutical Compounds; 6.1 Premise: Conformational Energy Barriers in Flexible Molecules; 6.2 Conformational Topology and Crystallization of Chain Molecules
6.3 Conformational Polymorphism and Crystallization of Flexible Molecules6.4 Conformational Flexibility of Ring Molecules: Carbohydrates; 6.5 Hindered Conformational Isomerism: Atropisomerism; 6.6 Conclusion; Acknowledgments; References; Chapter 7: Tautomerism in Drug Delivery; 7.1 Broadband Dielectric Spectroscopy as a Powerful Tool for Investigating the Tautomerization Process in Condensed Materials; 7.2 Tautomerization Kinetics of Supercooled Pharmaceuticals; Acknowledgment; References; Chapter 8: Disorders in Pharmaceutical Polymers; 8.1 Polymers Architectures - Structural Disorders
8.2 Structural States and Phases Transitions
Record Nr. UNINA-9910136779403321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Disordered pharmaceutical materials / / edited by Marc Descamps
Disordered pharmaceutical materials / / edited by Marc Descamps
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Descrizione fisica 1 online resource (646 p.)
Soggetto topico Materials biomèdics
Biotecnologia farmacèutica
Pharmaceutical biotechnology
Biomedical materials
ISBN 3-527-65269-8
3-527-65272-8
3-527-65271-X
9783527652693
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright; Table of Contents; List of Contributors; Chapter 1: Some Facets of Molecular Disorder in Crystalline and Amorphous Pharmaceuticals; 1.1 The Crystal/Amorph Alternative; 1.2 Characteristics of the Disorder in Glass Formers; Acknowledgments; References; Chapter 2: Influence of Disorder on Dissolution; 2.1 Introduction; 2.2 Approaches to Enhance Solubility; 2.3 Measuring the Solubility Advantage of Amorphous Compounds; 2.4 Solid Dispersions; 2.5 Polymer Properties; 2.6 Drug-Polymer Interactions; 2.7 Polymer Concentration; 2.8 Other Formulation Components
2.9 Formulation Variables2.10 Reliable Measurement of Supersaturation; 2.11 Conclusion; References; Chapter 3: Crystal Imperfections in Molecular Crystals: Physical and Chemical Consequences; 3.1 Introduction; 3.2 General Aspects of Defects in Crystals; 3.3 Role of Imperfections in Reactivity and Stability - Chemistry in the Perfect and Imperfect Lattice; 3.4 Role in Physical Processes; 3.5 Concluding Remarks; References; Chapter 4: Observation and Characterization of Crystal Defects in Pharmaceutical Solids; 4.1 Introduction; 4.2 Techniques for Characterizing Defects within Crystals
4.3 Techniques for Characterizing Defects Emergent at Crystal Surfaces4.4 Techniques for Quantifying Defect Densities within Crystals; 4.5 The Complementarity of Techniques for Characterizing Defects; 4.6 Summary and Outlook; Acknowledgment; References; Chapter 5: "Enantiomeric Disorder" Pharmaceutically Oriented; 5.1 Introduction; 5.2 Introduction and Lexicon of Specific Terms Used among Chiral Molecules and Chiral Molecular Associations; 5.3 Restrictions in Symmetry Operations Inside Crystal Lattices with an Enantiomeric Excess Different from Zero
5.4 Impact of Chirality on Phase Diagrams and the Gibbs-Scott Phase Rule5.5 Competitions between Solid Solutions (Impact of Polymorphism on Solid Solutions) Application: Preferential Enrichment; 5.6 Disorder at Level 3 Multiepitaxy between Enantiomers; 5.7 Conclusion and Perspectives; Acknowledgments; References; Chapter 6: Conformational Disorder and Atropisomerism in Pharmaceutical Compounds; 6.1 Premise: Conformational Energy Barriers in Flexible Molecules; 6.2 Conformational Topology and Crystallization of Chain Molecules
6.3 Conformational Polymorphism and Crystallization of Flexible Molecules6.4 Conformational Flexibility of Ring Molecules: Carbohydrates; 6.5 Hindered Conformational Isomerism: Atropisomerism; 6.6 Conclusion; Acknowledgments; References; Chapter 7: Tautomerism in Drug Delivery; 7.1 Broadband Dielectric Spectroscopy as a Powerful Tool for Investigating the Tautomerization Process in Condensed Materials; 7.2 Tautomerization Kinetics of Supercooled Pharmaceuticals; Acknowledgment; References; Chapter 8: Disorders in Pharmaceutical Polymers; 8.1 Polymers Architectures - Structural Disorders
8.2 Structural States and Phases Transitions
Record Nr. UNINA-9910830561803321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Encyclopedia of polymer blends . Volume 2 Processing / / edited by Avraam I. Isayev
Encyclopedia of polymer blends . Volume 2 Processing / / edited by Avraam I. Isayev
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2011]
Descrizione fisica 1 online resource (425 p.)
Disciplina 668.9
Collana Encyclopedia of Polymer Blends
Soggetto topico Polymers
Plastics
Soggetto genere / forma Electronic books.
ISBN 3-527-80522-2
3-527-80521-4
3-527-80524-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Encyclopedia of Polymer Blends; Contents; Preface; List of Contributors; 1: Polymer Blend Compounding and Processing; 1.1 Introduction and Early Studies of Blending; 1.2 Methods of Compounding; 1.2.1 Batch Mixers; 1.2.1.1 Introductory; 1.2.1.2 Non-intermeshing Rotor Mixers; 1.2.1.3 Intermeshing Rotor Mixers; 1.2.1.4 Post-World War II Development; 1.2.2 Continuous Mixers; 1.2.2.1 Early Activities; 1.2.2.2 Single-Screw Extrusion; 1.2.2.3 Co-rotating Twin-Screw Extrusion; 1.2.2.4 Tangential Counter-Rotating Twin-Screw Extrusion; 1.2.2.5 Modular Intermeshing Counter-Rotating Twin-Screw Mixer
1.2.2.6 Modular Buss Kokneter1.2.3 Comparisons; 1.3 Processing Polymer Blends; 1.3.1 Early Synthetic Polymer Blends; 1.3.2 General Ideas and Stability of Blend Phase Morphology; 1.3.3 Phase Morphology Variations in Processing Operations; 1.3.3.1 Melt Spinning; 1.3.3.2 Die Extrusion; 1.3.3.3 Injection Molding; References; 2: Rheology of Polymer Blends; 2.1 Introduction; 2.1.1 Rheological Models for Miscible Blends; 2.1.1.1 Solutions; 2.1.1.2 Homologous Polymer Blends; 2.1.2 Model Systems for Immiscible Blends; 2.1.2.1 Interphase and Percolation; 2.1.2.2 Suspensions; 2.1.2.3 Emulsion Rheology
2.1.2.4 Melt Flow of Block Copolymers2.2 Theoretical Treatment of Polymer Blends; 2.3 Rheology of Miscible Blends; 2.3.1 General; 2.3.2 Phase Separation and Flow; 2.3.2.1 Influence of Thermodynamics on Rheology; 2.3.2.2 Influence of Rheology on Thermodynamics; 2.4 Rheology of Immiscible Blends; 2.4.1 Rheological Equations of State; 2.4.2 Morphology of Immiscible Blends; 2.4.3 Microrheology of Polymer Blends; 2.4.3.1 Deformation and Breakup of Viscoelastic Drops; 2.4.3.2 Coalescence of Viscoelastic Drops; 2.4.4 Flow Imposed Morphology; 2.4.5 Shear Flows
2.4.5.1 Concentration Dependence of Viscosity2.4.5.2 Dynamic Flow; 2.4.5.3 Steady-State versus Dynamic Viscosity; 2.4.5.4 Blend Elasticity; 2.4.6 Elongational Flows; 2.5 Rheology of Blends with Nanoparticles; 2.5.1 General; 2.5.2 Rheology of Blends with Spherical SiO2 Particles; 2.5.3 Rheology of Blends with Nanoparticles Near Binodal; 2.5.4 Rheology of Immiscible Blends with Organoclay; 2.6 Conclusions; References; 3: Compounding and Processing of Plastic/Rubber Blends; 3.1 Plastic/Rubber Blends; 3.1.1 Introduction; 3.1.2 Classification of Polymer Blends; 3.1.3 Types of Plastic/Rubber Blends
3.2 Methods of Blend Preparation3.3 Equipment for Blend Preparation by Melt Mixing of Polymers; 3.3.1 Batch Mixers; 3.3.1.1 Roll Mill; 3.3.1.2 Banbury or Kneader Mixer; 3.3.2 Continuous Mixers; 3.3.2.1 Twin-Screw Mixer; 3.3.2.2 Buss Continuous Kneader; 3.4 Preparation of Physical Blends of Plastics and Rubbers; 3.4.1 Laboratory Preparation of the Blends; 3.4.2 Production of Blends by a Batch Process; 3.4.3 Production of Blends by a Continuous Process in a Twin-Screw Mixer; 3.5 Crosslinking Agents and Crosslinking Processes; 3.6 Preparation of the Blends of Plastics and Crosslinked Rubbers
3.6.1 Preparation of Plastic and Crosslinked Rubber Blends (TPVs) by a Batch Process
Record Nr. UNINA-9910134851103321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Encyclopedia of polymer blends . Volume 2 Processing / / edited by Avraam I. Isayev
Encyclopedia of polymer blends . Volume 2 Processing / / edited by Avraam I. Isayev
Pubbl/distr/stampa Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2011]
Descrizione fisica 1 online resource (425 p.)
Disciplina 668.9
Collana Encyclopedia of Polymer Blends
Soggetto topico Polymers
Plastics
ISBN 3-527-80522-2
3-527-80521-4
3-527-80524-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Encyclopedia of Polymer Blends; Contents; Preface; List of Contributors; 1: Polymer Blend Compounding and Processing; 1.1 Introduction and Early Studies of Blending; 1.2 Methods of Compounding; 1.2.1 Batch Mixers; 1.2.1.1 Introductory; 1.2.1.2 Non-intermeshing Rotor Mixers; 1.2.1.3 Intermeshing Rotor Mixers; 1.2.1.4 Post-World War II Development; 1.2.2 Continuous Mixers; 1.2.2.1 Early Activities; 1.2.2.2 Single-Screw Extrusion; 1.2.2.3 Co-rotating Twin-Screw Extrusion; 1.2.2.4 Tangential Counter-Rotating Twin-Screw Extrusion; 1.2.2.5 Modular Intermeshing Counter-Rotating Twin-Screw Mixer
1.2.2.6 Modular Buss Kokneter1.2.3 Comparisons; 1.3 Processing Polymer Blends; 1.3.1 Early Synthetic Polymer Blends; 1.3.2 General Ideas and Stability of Blend Phase Morphology; 1.3.3 Phase Morphology Variations in Processing Operations; 1.3.3.1 Melt Spinning; 1.3.3.2 Die Extrusion; 1.3.3.3 Injection Molding; References; 2: Rheology of Polymer Blends; 2.1 Introduction; 2.1.1 Rheological Models for Miscible Blends; 2.1.1.1 Solutions; 2.1.1.2 Homologous Polymer Blends; 2.1.2 Model Systems for Immiscible Blends; 2.1.2.1 Interphase and Percolation; 2.1.2.2 Suspensions; 2.1.2.3 Emulsion Rheology
2.1.2.4 Melt Flow of Block Copolymers2.2 Theoretical Treatment of Polymer Blends; 2.3 Rheology of Miscible Blends; 2.3.1 General; 2.3.2 Phase Separation and Flow; 2.3.2.1 Influence of Thermodynamics on Rheology; 2.3.2.2 Influence of Rheology on Thermodynamics; 2.4 Rheology of Immiscible Blends; 2.4.1 Rheological Equations of State; 2.4.2 Morphology of Immiscible Blends; 2.4.3 Microrheology of Polymer Blends; 2.4.3.1 Deformation and Breakup of Viscoelastic Drops; 2.4.3.2 Coalescence of Viscoelastic Drops; 2.4.4 Flow Imposed Morphology; 2.4.5 Shear Flows
2.4.5.1 Concentration Dependence of Viscosity2.4.5.2 Dynamic Flow; 2.4.5.3 Steady-State versus Dynamic Viscosity; 2.4.5.4 Blend Elasticity; 2.4.6 Elongational Flows; 2.5 Rheology of Blends with Nanoparticles; 2.5.1 General; 2.5.2 Rheology of Blends with Spherical SiO2 Particles; 2.5.3 Rheology of Blends with Nanoparticles Near Binodal; 2.5.4 Rheology of Immiscible Blends with Organoclay; 2.6 Conclusions; References; 3: Compounding and Processing of Plastic/Rubber Blends; 3.1 Plastic/Rubber Blends; 3.1.1 Introduction; 3.1.2 Classification of Polymer Blends; 3.1.3 Types of Plastic/Rubber Blends
3.2 Methods of Blend Preparation3.3 Equipment for Blend Preparation by Melt Mixing of Polymers; 3.3.1 Batch Mixers; 3.3.1.1 Roll Mill; 3.3.1.2 Banbury or Kneader Mixer; 3.3.2 Continuous Mixers; 3.3.2.1 Twin-Screw Mixer; 3.3.2.2 Buss Continuous Kneader; 3.4 Preparation of Physical Blends of Plastics and Rubbers; 3.4.1 Laboratory Preparation of the Blends; 3.4.2 Production of Blends by a Batch Process; 3.4.3 Production of Blends by a Continuous Process in a Twin-Screw Mixer; 3.5 Crosslinking Agents and Crosslinking Processes; 3.6 Preparation of the Blends of Plastics and Crosslinked Rubbers
3.6.1 Preparation of Plastic and Crosslinked Rubber Blends (TPVs) by a Batch Process
Record Nr. UNINA-9910829969603321
Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Company KGaA, , [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui