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"Topics in anti-cancer research." . Volume 4 / / editors, Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge, UK & Khurshid Zaman, Bentham Science Publishers, USA
"Topics in anti-cancer research." . Volume 4 / / editors, Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge, UK & Khurshid Zaman, Bentham Science Publishers, USA
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (817 p.)
Collana Topics in Anti-Cancer Research
Soggetto topico Cancer - Research
Cancer - Prevention
ISBN 1-68108-076-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; FOREWORD ; List of Contributors ; Targeted Cancer Therapy: The Roles Played by Antibody-Drug and Antibody-Toxin Conjugates ; 1. INTRODUCTION; 2. IMMUNOTOXINS; 2.1. Pseudomonas Exotoxin-Based Immunotoxins; 2.2. Pseudomonas Exotoxin-Based ITs in Treating Solid Tumors; 2.3. Diphtheria Toxin-Based Immunotoxins; 2.4. Ribosome Inactivating Proteins-Based Immunotoxins; 2.4.1. Ricin; 2.4.2. Recombinant constructs of RIP I toxins; 2.5. Ribonucleases-Based IT; 2.6. Proapoptotic Proteins Used As Targeted Immunotoxins/Chimeric Proteins; 2.7. Current & Future Developments of ITs
3. ANTIBODY-DRUG CONJUGATES 3.1. DNA Interacting Agents-Calicheamicins; 3.2. DNA Interacting Agents-Duocarmycins; 3.3. DNA Interacting Agents-Pyrrolo[1,4]Benzodiazepines; 3.4. Tubulin Interacting Agents-Auristatins; 3.5. Tubulin Interacting Agents-Maytansinoids; 3.6. Other Anticancer Drugs Conjugated to mAbs; 4. CURRENT AND FUTURE DEVELOPMENTS OF ADC ; DISCLOSURE; CONFLICTS OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Targeting Cell Surface Nucleolin in Cancer ; INTRODUCTION; CELL SURFACE LOCALIZATION OF NCL; LIGANDS OF CELL SURFACE NCL
CELL SURFACE NCL-DEPENDENT LIGAND SPECIFIC INTERNALIZATIONCELL SURFACE NCL AND SIGNALING COMPLEXES; TARGETING CELL SURFACE NCL; CELL SURFACE NCL AS BIOMARKER FOR CANCER; PATENTS RELATED TO NCL; CURRENT & FUTURE DEVELOPMENTS; DISCLOSURE; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Anticancer Agents Targeting Tubulin ; 1. INTRODUCTION; 2. MICROTUBULE DESTABLIZERS; 2.1. Colchicine; 2.2. Combretastatin A-4 (CA-A4); 2.3. Chalcones; 2.4. Phenstatins; 2.5. Podophyllotoxin; 2.6. Vinca Alkaloids; 2.7. Other Tubulin Polymerization Inhibitors; 3. MICROTUBULE STABLIZERS; 3.1. Taxol®
3.2. Other Tubulin Depolymerization InhibitorsDrugs Bind to Microtubule-Associated Proteins (MAPs); Peripheral Neuropathy Induced by Anti Mitotic Agents [177]; Role of β-Tubulin Isotypes in Drug Binding [178]; 4. RECENT PATENTS; 4.1. Research Corporation Technologies Patents; 4.2. Brandeis University Patents; 4.3. Tuse et al. Patents; 4.4. Pinney et al. Patents; 4.5. Aventis Pharma Patents (2001); 4.6. Davis et al. Patents; 4.7. Aventis Pharma Patents (2003); 4.8. Chang et al. Patents; 4.9. Hadfield et al. Patents; 4.10. Rigel Pharmaceuticals Patents; 4.11. NIH Patents
4.12. Cytopia Pty Ltd Patents4.13. Galemmo et al. Patents; 4.14. Pettit et al. Patents; 4.15. Patent by Aneja et al.; 4.16. Wyeth Holding Corporation Patents; 4.17. Champions Biotechnologypatents; 4.18. Bionomics Ltd. Patents; 4.19. Janssen Pharmaceutica Patents; 4.20. Exonhit Patents; 4.21. Centre National De La Recherche Scientifique Patents; 4.22. Development Centre of Biotechnology Patents; 4.23. Y M Biosciences Pty Ltd. Patents ; 4.24. Patents by Gangjee et al.; 4.25. Thorson et al. Patents; 4.26. Bionomics Ltd. Patents ; 4.27. Chen et al. (2014); 4.28. Wang et al. (2014)
4.29. Burns et al. (2014)
Record Nr. UNINA-9910797787003321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
"Topics in anti-cancer research." . Volume 4 / / editors, Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge, UK & Khurshid Zaman, Bentham Science Publishers, USA
"Topics in anti-cancer research." . Volume 4 / / editors, Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge, UK & Khurshid Zaman, Bentham Science Publishers, USA
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (817 p.)
Collana Topics in Anti-Cancer Research
Soggetto topico Cancer - Research
Cancer - Prevention
ISBN 1-68108-076-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; FOREWORD ; List of Contributors ; Targeted Cancer Therapy: The Roles Played by Antibody-Drug and Antibody-Toxin Conjugates ; 1. INTRODUCTION; 2. IMMUNOTOXINS; 2.1. Pseudomonas Exotoxin-Based Immunotoxins; 2.2. Pseudomonas Exotoxin-Based ITs in Treating Solid Tumors; 2.3. Diphtheria Toxin-Based Immunotoxins; 2.4. Ribosome Inactivating Proteins-Based Immunotoxins; 2.4.1. Ricin; 2.4.2. Recombinant constructs of RIP I toxins; 2.5. Ribonucleases-Based IT; 2.6. Proapoptotic Proteins Used As Targeted Immunotoxins/Chimeric Proteins; 2.7. Current & Future Developments of ITs
3. ANTIBODY-DRUG CONJUGATES 3.1. DNA Interacting Agents-Calicheamicins; 3.2. DNA Interacting Agents-Duocarmycins; 3.3. DNA Interacting Agents-Pyrrolo[1,4]Benzodiazepines; 3.4. Tubulin Interacting Agents-Auristatins; 3.5. Tubulin Interacting Agents-Maytansinoids; 3.6. Other Anticancer Drugs Conjugated to mAbs; 4. CURRENT AND FUTURE DEVELOPMENTS OF ADC ; DISCLOSURE; CONFLICTS OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Targeting Cell Surface Nucleolin in Cancer ; INTRODUCTION; CELL SURFACE LOCALIZATION OF NCL; LIGANDS OF CELL SURFACE NCL
CELL SURFACE NCL-DEPENDENT LIGAND SPECIFIC INTERNALIZATIONCELL SURFACE NCL AND SIGNALING COMPLEXES; TARGETING CELL SURFACE NCL; CELL SURFACE NCL AS BIOMARKER FOR CANCER; PATENTS RELATED TO NCL; CURRENT & FUTURE DEVELOPMENTS; DISCLOSURE; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Anticancer Agents Targeting Tubulin ; 1. INTRODUCTION; 2. MICROTUBULE DESTABLIZERS; 2.1. Colchicine; 2.2. Combretastatin A-4 (CA-A4); 2.3. Chalcones; 2.4. Phenstatins; 2.5. Podophyllotoxin; 2.6. Vinca Alkaloids; 2.7. Other Tubulin Polymerization Inhibitors; 3. MICROTUBULE STABLIZERS; 3.1. Taxol®
3.2. Other Tubulin Depolymerization InhibitorsDrugs Bind to Microtubule-Associated Proteins (MAPs); Peripheral Neuropathy Induced by Anti Mitotic Agents [177]; Role of β-Tubulin Isotypes in Drug Binding [178]; 4. RECENT PATENTS; 4.1. Research Corporation Technologies Patents; 4.2. Brandeis University Patents; 4.3. Tuse et al. Patents; 4.4. Pinney et al. Patents; 4.5. Aventis Pharma Patents (2001); 4.6. Davis et al. Patents; 4.7. Aventis Pharma Patents (2003); 4.8. Chang et al. Patents; 4.9. Hadfield et al. Patents; 4.10. Rigel Pharmaceuticals Patents; 4.11. NIH Patents
4.12. Cytopia Pty Ltd Patents4.13. Galemmo et al. Patents; 4.14. Pettit et al. Patents; 4.15. Patent by Aneja et al.; 4.16. Wyeth Holding Corporation Patents; 4.17. Champions Biotechnologypatents; 4.18. Bionomics Ltd. Patents; 4.19. Janssen Pharmaceutica Patents; 4.20. Exonhit Patents; 4.21. Centre National De La Recherche Scientifique Patents; 4.22. Development Centre of Biotechnology Patents; 4.23. Y M Biosciences Pty Ltd. Patents ; 4.24. Patents by Gangjee et al.; 4.25. Thorson et al. Patents; 4.26. Bionomics Ltd. Patents ; 4.27. Chen et al. (2014); 4.28. Wang et al. (2014)
4.29. Burns et al. (2014)
Record Nr. UNINA-9910807290903321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in HIV treatment : HIV enzyme inhibitors and antiretroviral therapy / / edited by Gene D. Morse, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo (UB), Buffalo, New York, USA & Sarah Nanzigu, Department of Pharmacology and Therapeutics, Makerere University College of Health Science, Kampala, Uganda
Advances in HIV treatment : HIV enzyme inhibitors and antiretroviral therapy / / edited by Gene D. Morse, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo (UB), Buffalo, New York, USA & Sarah Nanzigu, Department of Pharmacology and Therapeutics, Makerere University College of Health Science, Kampala, Uganda
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (168 p.)
Collana Frontiers in HIV research
Soggetto topico HIV infections - Prevention
Soggetto genere / forma Electronic books.
ISBN 1-68108-056-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 COver; 02 Title; 03 F End User Licence Terms - Non-Institutional Personal Use; 04 Contents; 05 Foreword; 06 Preface; 07 LOC; 07b Acknowledgements; 08 Chapter 01; 08 Chapter 02; 08 Chapter 03; 08 Chapter 04; 08 Chapter 05; 08 Chapter 06; 08 Chapter 07; 08 Chapter 08; 09 Index; 10 Back COver
Record Nr. UNINA-9910460726003321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in HIV treatment : HIV enzyme inhibitors and antiretroviral therapy / / edited by Gene D. Morse, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo (UB), Buffalo, New York, USA & Sarah Nanzigu, Department of Pharmacology and Therapeutics, Makerere University College of Health Science, Kampala, Uganda
Advances in HIV treatment : HIV enzyme inhibitors and antiretroviral therapy / / edited by Gene D. Morse, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo (UB), Buffalo, New York, USA & Sarah Nanzigu, Department of Pharmacology and Therapeutics, Makerere University College of Health Science, Kampala, Uganda
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (168 p.)
Collana Frontiers in HIV research
Soggetto topico HIV infections - Prevention
ISBN 1-68108-056-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 COver; 02 Title; 03 F End User Licence Terms - Non-Institutional Personal Use; 04 Contents; 05 Foreword; 06 Preface; 07 LOC; 07b Acknowledgements; 08 Chapter 01; 08 Chapter 02; 08 Chapter 03; 08 Chapter 04; 08 Chapter 05; 08 Chapter 06; 08 Chapter 07; 08 Chapter 08; 09 Index; 10 Back COver
Record Nr. UNINA-9910797702703321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in HIV treatment : HIV enzyme inhibitors and antiretroviral therapy / / edited by Gene D. Morse, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo (UB), Buffalo, New York, USA & Sarah Nanzigu, Department of Pharmacology and Therapeutics, Makerere University College of Health Science, Kampala, Uganda
Advances in HIV treatment : HIV enzyme inhibitors and antiretroviral therapy / / edited by Gene D. Morse, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo (UB), Buffalo, New York, USA & Sarah Nanzigu, Department of Pharmacology and Therapeutics, Makerere University College of Health Science, Kampala, Uganda
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (168 p.)
Collana Frontiers in HIV research
Soggetto topico HIV infections - Prevention
ISBN 1-68108-056-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 COver; 02 Title; 03 F End User Licence Terms - Non-Institutional Personal Use; 04 Contents; 05 Foreword; 06 Preface; 07 LOC; 07b Acknowledgements; 08 Chapter 01; 08 Chapter 02; 08 Chapter 03; 08 Chapter 04; 08 Chapter 05; 08 Chapter 06; 08 Chapter 07; 08 Chapter 08; 09 Index; 10 Back COver
Record Nr. UNINA-9910808240403321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Common pathogenic mechanisms between Down Syndrome and Alzheimer's disease steps toward therapy / / editors, Ahmad Salehi, Department of Pyschiatry and Behavioral Sciences, Stanford University School of Medicine and VA Palo Alto Health, Care System (WRIISC), Palo Alto, California, USA, Michael Rafii, Department of Neurosciences, University of California, San Diego, California, USA & Cristy Phillips, Department of Physical Therapy, Arkansas State University, Jonesboro, Arkansas, USA
Common pathogenic mechanisms between Down Syndrome and Alzheimer's disease steps toward therapy / / editors, Ahmad Salehi, Department of Pyschiatry and Behavioral Sciences, Stanford University School of Medicine and VA Palo Alto Health, Care System (WRIISC), Palo Alto, California, USA, Michael Rafii, Department of Neurosciences, University of California, San Diego, California, USA & Cristy Phillips, Department of Physical Therapy, Arkansas State University, Jonesboro, Arkansas, USA
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (322 p.)
Collana Recent advances in Alzheimer research
Soggetto topico Alzheimer's disease - Treatment
Down syndrome - Treatment
Soggetto genere / forma Electronic books.
ISBN 1-68108-138-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title; EUL; Dedication; Contents; Preface; Acknowledgements; Chatper 01; Chatper 02; Chatper 03; Chatper 04; Chatper 05; Chatper 06; Chatper 07; Chatper 08; Chatper 09; Chapter 10; Chatper 11; Chatper 12; Chatper 13; Conclusion; Index; Back Cover
Record Nr. UNINA-9910460724803321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Common pathogenic mechanisms between Down Syndrome and Alzheimer's disease steps toward therapy / / editors, Ahmad Salehi, Department of Pyschiatry and Behavioral Sciences, Stanford University School of Medicine and VA Palo Alto Health, Care System (WRIISC), Palo Alto, California, USA, Michael Rafii, Department of Neurosciences, University of California, San Diego, California, USA & Cristy Phillips, Department of Physical Therapy, Arkansas State University, Jonesboro, Arkansas, USA
Common pathogenic mechanisms between Down Syndrome and Alzheimer's disease steps toward therapy / / editors, Ahmad Salehi, Department of Pyschiatry and Behavioral Sciences, Stanford University School of Medicine and VA Palo Alto Health, Care System (WRIISC), Palo Alto, California, USA, Michael Rafii, Department of Neurosciences, University of California, San Diego, California, USA & Cristy Phillips, Department of Physical Therapy, Arkansas State University, Jonesboro, Arkansas, USA
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (322 p.)
Collana Recent advances in Alzheimer research
Soggetto topico Alzheimer's disease - Treatment
Down syndrome - Treatment
ISBN 1-68108-138-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title; EUL; Dedication; Contents; Preface; Acknowledgements; Chatper 01; Chatper 02; Chatper 03; Chatper 04; Chatper 05; Chatper 06; Chatper 07; Chatper 08; Chatper 09; Chapter 10; Chatper 11; Chatper 12; Chatper 13; Conclusion; Index; Back Cover
Record Nr. UNINA-9910797702603321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Common pathogenic mechanisms between Down Syndrome and Alzheimer's disease steps toward therapy / / editors, Ahmad Salehi, Department of Pyschiatry and Behavioral Sciences, Stanford University School of Medicine and VA Palo Alto Health, Care System (WRIISC), Palo Alto, California, USA, Michael Rafii, Department of Neurosciences, University of California, San Diego, California, USA & Cristy Phillips, Department of Physical Therapy, Arkansas State University, Jonesboro, Arkansas, USA
Common pathogenic mechanisms between Down Syndrome and Alzheimer's disease steps toward therapy / / editors, Ahmad Salehi, Department of Pyschiatry and Behavioral Sciences, Stanford University School of Medicine and VA Palo Alto Health, Care System (WRIISC), Palo Alto, California, USA, Michael Rafii, Department of Neurosciences, University of California, San Diego, California, USA & Cristy Phillips, Department of Physical Therapy, Arkansas State University, Jonesboro, Arkansas, USA
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (322 p.)
Collana Recent advances in Alzheimer research
Soggetto topico Alzheimer's disease - Treatment
Down syndrome - Treatment
ISBN 1-68108-138-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title; EUL; Dedication; Contents; Preface; Acknowledgements; Chatper 01; Chatper 02; Chatper 03; Chatper 04; Chatper 05; Chatper 06; Chatper 07; Chatper 08; Chatper 09; Chapter 10; Chatper 11; Chatper 12; Chatper 13; Conclusion; Index; Back Cover
Record Nr. UNINA-9910808460603321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Depression : a silent culprit in health and disease / / editors, Puneetpal Singh, PhD, Human Genetics, Punjabi University, Patiala, India & Sarabjit Mastana, PhD, Genomics Lab, Sport, Exercise and Health Sciences, Loughborough University, UK
Depression : a silent culprit in health and disease / / editors, Puneetpal Singh, PhD, Human Genetics, Punjabi University, Patiala, India & Sarabjit Mastana, PhD, Genomics Lab, Sport, Exercise and Health Sciences, Loughborough University, UK
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (137 p.)
Soggetto topico Depression, Mental
Soggetto genere / forma Electronic books.
ISBN 1-68108-145-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 Cover; 02 Title; 03 F End User Licence Terms - Non-Institutional Personal Use; 04a Dedication; 04b Contents; 05 Preface; 07 LOC; 08 Chapter 01; 08 Chapter 02; 08 Chapter 03; 08 Chapter 04; 08 Chapter 05; 09 Index
Record Nr. UNINA-9910460654503321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Depression : a silent culprit in health and disease / / editors, Puneetpal Singh, PhD, Human Genetics, Punjabi University, Patiala, India & Sarabjit Mastana, PhD, Genomics Lab, Sport, Exercise and Health Sciences, Loughborough University, UK
Depression : a silent culprit in health and disease / / editors, Puneetpal Singh, PhD, Human Genetics, Punjabi University, Patiala, India & Sarabjit Mastana, PhD, Genomics Lab, Sport, Exercise and Health Sciences, Loughborough University, UK
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Descrizione fisica 1 online resource (137 p.)
Soggetto topico Depression, Mental
ISBN 1-68108-145-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 Cover; 02 Title; 03 F End User Licence Terms - Non-Institutional Personal Use; 04a Dedication; 04b Contents; 05 Preface; 07 LOC; 08 Chapter 01; 08 Chapter 02; 08 Chapter 03; 08 Chapter 04; 08 Chapter 05; 09 Index
Record Nr. UNINA-9910797771703321
Sharjah : , : Bentham Science Publishers, Limited, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui

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