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Accessing uncultivated microorganisms : from the environment to organisms and genomes and back / edited by Karsten Zengler
Accessing uncultivated microorganisms : from the environment to organisms and genomes and back / edited by Karsten Zengler
Pubbl/distr/stampa Washington, : ASM Press, c2008
Descrizione fisica XII, 308 p. : ill. ; 26 cm
Disciplina 576.15
579.17
Soggetto non controllato Ecologia dei microrganismi
ISBN 978-1-55581-406-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-990008809860403321
Washington, : ASM Press, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antibiotics : challenges, mechanisms, opportunities / / by Christopher Walsh and Timothy Wencewicz
Antibiotics : challenges, mechanisms, opportunities / / by Christopher Walsh and Timothy Wencewicz
Autore Walsh Christopher
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2016
Descrizione fisica 1 online resource (490 p.)
Disciplina 615.329
Soggetto topico Antibiotics
Drug resistance in microorganisms
Soggetto genere / forma Electronic books.
ISBN 1-68367-331-X
1-55581-931-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Section I: Challenges for Antibiotics; 1 Antibiotics: Initial Concepts and Considerations; Waves of Resistant Bacterial Infections; Differential Susceptibility to Antibiotics; Empiric Therapy and Broad-spectrum Antibiotics; Antibiotic Flow Chart; Recent Approvals and the Current Antibiotic Pipeline; Recognition of Pressing Need for New Antibiotics: "The End is Near" Scenarios; Approach and Organization of This Volume; 2 Major Classes of Antibiotics and Their Modes of Action; Antibiotics Versus Antimicrobials: Antibacterial Versus Antifungal Versus Antiprotozoal Agents
What Bacteria to TargetHow to Test for Antibiotic Activity; How to Find Antibiotics; A Golden Age of Antibiotic Medicinal Chemistry; What is the Capacity for Microbes to Make Antibiotics?; Target Classes Identified from the Major Antibiotic Groups; A Common Pathway for Bactericidal Antibiotics?; Section II: Mechanisms: Antibiotic Action by Bacterial Target Class; 3 Assembly of the Peptidoglycan Layer of Bacterial Cell Walls; Introduction; Nature of the PG Layer of the Cell Envelope; Biosynthesis and Insertion of PG Monomer Units
PG Assembly: Phase 1 in the Cytoplasm-Generation of UDP-Muramyl PentapeptidePG Assembly: Phase 2 at the Inner Face of the Cytoplasmic Membrane-the C55 Bactoprenol Lipid Carrier; PG Assembly: Phase III-Chain Extension and Cross-Linking at the Outer Face of the Cytoplasmic Membrane; Summary; 4 Antibiotics That Block Peptidoglycan Assembly and Integrity; Introduction; PG Transpeptidase Inhibition: β-Lactam Antibiotics; Four Subclasses of Antibiotics: Penams, Cephems, Carbapenems, and Monobactams; Mechanisms of Action of Lactam Antibiotics: Acylation of Transpeptidases; The Families of PBPs
Acyl Enzyme Lifetimes Are CrucialPBP Inventories; Many Side Chain Variants in Semisynthetic β-Lactam Antibiotics; The Future for β-Lactam Antibiotics?; Moenomycin: Inhibition of PG Transglycosylases; Antibiotics That Act as Substrate Binders and Sequestrants in the Bactoprenol Metabolic Cycle; MraY and Peptidyl Nucleoside Antibiotics; How Do Bacteria Respond to Categories of Antibiotics That Target the Cell Wall?; 5 Antibiotics That Disrupt Membrane Integrity; Introduction; Antimicrobial Peptides and Defensins; Lantibiotic Peptides
Calprotectin, an Antimicrobial Protein That Complexes Mn(II) and Fe(II)Bacterial Lipopeptides; Surfactin; Daptomycin Disrupts Bacterial Membrane Integrity; Polymyxin: an Old Antibiotic Revisited; Dual Mechanisms for SecondGeneration Lipoglycopeptide Antibiotics; 6 Antibiotics That Block Protein Synthesis; Overview of Bacterial Protein Synthesis; Antibiotics That Target Aminoacyl-tRNA Synthetases; Antibiotics That Target the Bacterial Ribosome; EF-Tu: an Aminoacyl-tRNA Chaperone as Antibiotic Target; 7 Antibiotics That Target DNA and RNA Information Transfer
Antibiotics Directed against Type II Topoisomerases
Record Nr. UNINA-9910555016503321
Walsh Christopher  
Washington, District of Columbia : , : ASM Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antibiotics : challenges, mechanisms, opportunities / / by Christopher Walsh and Timothy Wencewicz
Antibiotics : challenges, mechanisms, opportunities / / by Christopher Walsh and Timothy Wencewicz
Autore Walsh Christopher
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2016
Descrizione fisica 1 online resource (490 p.)
Disciplina 615.329
Soggetto topico Antibiotics
Drug resistance in microorganisms
ISBN 1-68367-331-X
1-55581-931-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Section I: Challenges for Antibiotics; 1 Antibiotics: Initial Concepts and Considerations; Waves of Resistant Bacterial Infections; Differential Susceptibility to Antibiotics; Empiric Therapy and Broad-spectrum Antibiotics; Antibiotic Flow Chart; Recent Approvals and the Current Antibiotic Pipeline; Recognition of Pressing Need for New Antibiotics: "The End is Near" Scenarios; Approach and Organization of This Volume; 2 Major Classes of Antibiotics and Their Modes of Action; Antibiotics Versus Antimicrobials: Antibacterial Versus Antifungal Versus Antiprotozoal Agents
What Bacteria to TargetHow to Test for Antibiotic Activity; How to Find Antibiotics; A Golden Age of Antibiotic Medicinal Chemistry; What is the Capacity for Microbes to Make Antibiotics?; Target Classes Identified from the Major Antibiotic Groups; A Common Pathway for Bactericidal Antibiotics?; Section II: Mechanisms: Antibiotic Action by Bacterial Target Class; 3 Assembly of the Peptidoglycan Layer of Bacterial Cell Walls; Introduction; Nature of the PG Layer of the Cell Envelope; Biosynthesis and Insertion of PG Monomer Units
PG Assembly: Phase 1 in the Cytoplasm-Generation of UDP-Muramyl PentapeptidePG Assembly: Phase 2 at the Inner Face of the Cytoplasmic Membrane-the C55 Bactoprenol Lipid Carrier; PG Assembly: Phase III-Chain Extension and Cross-Linking at the Outer Face of the Cytoplasmic Membrane; Summary; 4 Antibiotics That Block Peptidoglycan Assembly and Integrity; Introduction; PG Transpeptidase Inhibition: β-Lactam Antibiotics; Four Subclasses of Antibiotics: Penams, Cephems, Carbapenems, and Monobactams; Mechanisms of Action of Lactam Antibiotics: Acylation of Transpeptidases; The Families of PBPs
Acyl Enzyme Lifetimes Are CrucialPBP Inventories; Many Side Chain Variants in Semisynthetic β-Lactam Antibiotics; The Future for β-Lactam Antibiotics?; Moenomycin: Inhibition of PG Transglycosylases; Antibiotics That Act as Substrate Binders and Sequestrants in the Bactoprenol Metabolic Cycle; MraY and Peptidyl Nucleoside Antibiotics; How Do Bacteria Respond to Categories of Antibiotics That Target the Cell Wall?; 5 Antibiotics That Disrupt Membrane Integrity; Introduction; Antimicrobial Peptides and Defensins; Lantibiotic Peptides
Calprotectin, an Antimicrobial Protein That Complexes Mn(II) and Fe(II)Bacterial Lipopeptides; Surfactin; Daptomycin Disrupts Bacterial Membrane Integrity; Polymyxin: an Old Antibiotic Revisited; Dual Mechanisms for SecondGeneration Lipoglycopeptide Antibiotics; 6 Antibiotics That Block Protein Synthesis; Overview of Bacterial Protein Synthesis; Antibiotics That Target Aminoacyl-tRNA Synthetases; Antibiotics That Target the Bacterial Ribosome; EF-Tu: an Aminoacyl-tRNA Chaperone as Antibiotic Target; 7 Antibiotics That Target DNA and RNA Information Transfer
Antibiotics Directed against Type II Topoisomerases
Record Nr. UNINA-9910831000803321
Walsh Christopher  
Washington, District of Columbia : , : ASM Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2015
Descrizione fisica 1 online resource (476 p.)
Disciplina 616.0798
Soggetto topico Immunoglobulins
Communicable diseases - Immunological aspects
ISBN 1-68367-340-9
1-68367-098-1
1-55581-741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS""
""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE""
""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""
""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG""
""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS""
Record Nr. UNINA-9910555131903321
Washington, District of Columbia : , : ASM Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2015
Descrizione fisica 1 online resource (476 p.)
Disciplina 616.0798
Soggetto topico Immunoglobulins
Communicable diseases - Immunological aspects
ISBN 1-68367-340-9
1-68367-098-1
1-55581-741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Contents ""; ""Contr ibutors ""; ""Preface ""; ""INTRODUCTION""; ""Chapter 1: History and Practice: Antibodies in Infectious Diseases""; ""HISTORICAL PERSPECTIVE""; ""INTRODUCTION TO ANTIBODIES""; ""METHODS AND PLATFORMS FOR GENERATING ANTIBODIES""; ""STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES""; ""EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES""; ""FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES""; ""ACKNOWLEDGMENT""; ""CITATION""
""REFERENCES""""GENERAL FEATURES OF IMMUNOGLOBULINS""; ""Chapter 2: Functions of Antibodies""; ""INTRODUCTION""; ""ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES""; ""INHIBITION OF LATER STEPS""; ""ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT""; ""ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS""; ""OTHER ANTIBODY FUNCTIONS""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 3: Antibody Structure""; ""BASICS OF ANTIBODY STRUCTURE""; ""CDR H3: SIZE AND SUBTERFUGE""; ""HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS""
""DISULFIDES IN THE CDRs""""SELF-CARBOHYDRATE RECOGNITION: PENETRATING THE GLYCAN SHIELD""; ""UNUSUAL INDELS""; ""MECHANISMS OF ANTIBODY NEUTRALIZATION""; ""SUMMARY""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases""; ""INTRODUCTION""; ""COMPLEMENT ACTIVATION""; ""Ab-MEDIATED COMPLEMENT ACTIVATION""; ""EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS""; ""MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES""; ""COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS""; ""CONCLUSIONS AND FUTURE PERSPECTIVE""
""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment""; ""IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES""; ""IgE ANTIBODIES IN INFECTIOUS DISEASES""; ""ANTIBODIES IN THE TREATMENT OF ALLERGIES""; ""THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY""; ""CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""
""ANTIBODY DISCOVERY APPROACHES""""Chapter 6: Phage and Yeast Display""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY""; ""DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY""; ""CONCLUSIONS""; ""ACKNOWLEDGMENT""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells""; ""MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES""; ""EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG""
""LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS""
Record Nr. UNINA-9910830911403321
Washington, District of Columbia : , : ASM Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antimicrobial agents : antibacterials and antifungals / edited by André Bryskier
Antimicrobial agents : antibacterials and antifungals / edited by André Bryskier
Pubbl/distr/stampa Washington : ASM Press, 2005
Descrizione fisica XXX, 1426 p. : ill. ; 29 cm
Disciplina 615.321
Soggetto non controllato Piante medicinali
Farmacognosia
ISBN 978-1-55581-237-9
1-55581-237-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-990009098970403321
Washington : ASM Press, 2005
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antimicrobial resistance in bacteria from livestock and companion animals / / editors, Stefan Schwarz, Lina Maria Cavaco, Jianzhong Shen ; with Frank Møller Aarestrup
Antimicrobial resistance in bacteria from livestock and companion animals / / editors, Stefan Schwarz, Lina Maria Cavaco, Jianzhong Shen ; with Frank Møller Aarestrup
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , [2018]
Descrizione fisica 1 online resource (746 pages)
Disciplina 616.9041
Soggetto topico Drug resistance in microorganisms
Antibiotics in veterinary medicine
ISBN 1-68367-295-X
1-68367-052-3
1-55581-980-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910555132703321
Washington, District of Columbia : , : ASM Press, , [2018]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antiretroviral therapy / edited by Erik D.A. De Clercq
Antiretroviral therapy / edited by Erik D.A. De Clercq
Pubbl/distr/stampa Washington : ASM Press, c2001
Descrizione fisica x, 359 p. : ill. ; 26 cm
Disciplina 616.97
Soggetto non controllato Biochimica
Scienze mediche - malattie sistema immunitario
ISBN 1-55581-156-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-990001494270403321
Washington : ASM Press, c2001
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antisepsis, disinfection, and sterilization : types, action, and resistance / / Gerald E. McDonnell
Antisepsis, disinfection, and sterilization : types, action, and resistance / / Gerald E. McDonnell
Autore McDonnell Gerald E.
Edizione [Second edition.]
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2017
Descrizione fisica 1 online resource (410 pages) : illustrations (some color)
Disciplina 614.4/8
Soggetto topico Sterilization
Asepsis and antisepsis
Disinfection and disinfectants
Soggetto genere / forma Electronic books.
ISBN 1-68367-307-7
1-68367-085-X
1-5231-1259-X
1-55581-968-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910555263803321
McDonnell Gerald E.  
Washington, District of Columbia : , : ASM Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antisepsis, disinfection, and sterilization : types, action, and resistance / / Gerald E. McDonnell
Antisepsis, disinfection, and sterilization : types, action, and resistance / / Gerald E. McDonnell
Autore McDonnell Gerald E.
Edizione [Second edition.]
Pubbl/distr/stampa Washington, District of Columbia : , : ASM Press, , 2017
Descrizione fisica 1 online resource (410 pages) : illustrations (some color)
Disciplina 614.4/8
Soggetto topico Sterilization
Asepsis and antisepsis
Disinfection and disinfectants
ISBN 1-68367-307-7
1-68367-085-X
1-5231-1259-X
1-55581-968-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910830302203321
McDonnell Gerald E.  
Washington, District of Columbia : , : ASM Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui