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Photo-induced metastability in amorphous semiconductors [[electronic resource] /] / [edited by] Alexander V. Kolobov ; with a foreword of Kazunobu Tanaka
Photo-induced metastability in amorphous semiconductors [[electronic resource] /] / [edited by] Alexander V. Kolobov ; with a foreword of Kazunobu Tanaka
Autore Kolobov Alexander V
Pubbl/distr/stampa Weinheim, : [Cambridge], : Wiley-VCH, c2003
Descrizione fisica 1 online resource (438 p.)
Disciplina 541.22
621.38152
Altri autori (Persone) KolobovAlexander V
Soggetto topico Amorphous semiconductors
Chemical structure
Soggetto genere / forma Electronic books.
ISBN 1-280-72298-3
9786610722983
3-527-60254-2
3-527-60866-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Photo-Induced Metastability in Amorphous Semiconductors; Preface; Introduction; Contents; List of Contributors; 1 Structure, Defects and Electronic Properties of Amorphous Semiconductors; 1.1 Structural States of Solids; 1.1.1 Ordered State; 1.1.2 Disordered (Non-Crystalline) State; 1.2 Atomic Scale Ordering in Crystalline and Non-Crystalline Solids; 1.2.1 Long-Range Order; 1.2.2 Short-Range Order; 1.2.3 Medium-Range Order; 1.3 Fundamental Problems of Structure of Non-Crystalline Semiconductors; 1.3.1 Tetrahedrally Bonded Amorphous Semiconductors
1.3.2 Amorphous Non-Tetrahedrally Bonded Semiconductors1.4 Defects in Non-Crystalline Solids; 1.4.1 Local Defects; 1.4.2 The Diffuse or Collective Defects (Extended Defects); 1.4.3 Chemical Defects; 1.4.4 Electronic-Structural Defects; 1.4.5 Macrodefects; 1.5 Electronic States in Amorphous Semiconductors; 1.5.1 Electronic States in Tetrahedrally Bonded Semiconductors; 1.5.2 Electronic States in Non-Tetrahedrally Bonded Semiconductors; References; 2 Photo-Induced Phenomena in Amorphous and Glassy Chalcogenides; 2.1 Introduction; 2.2 Photo-Induced Effects in Amorphous and Glassy Chalcogenides
2.2.1 Irreversible Photo-Induced Changes2.2.2 Reversible Photo-Induced Changes; 2.3 Applications; 2.4 Summary; References; 3 Short-, Medium- and Long-Range-Order Structural Transformations in Amorphous Semiconductors; 3.1 Introduction; 3.2 Short-Range-Order (SRO) Effects; 3.3 Medium-Range-Order (MRO) Effects; 3.4 Long-Range-Order (LRO) Effects; 3.5 Conclusion; References; 4 Dynamics of Photo-Induced Metastability in Amorphous Chalcogenides; 4.1 Introduction; 4.2 Light-Induced Metastable Defect (LIMD) Creation; 4.3 Photostructural Changes; 4.4 Discussion; 4.5 Conclusions; References
5 Sub-Gap Photo-Induced Phenomena in Chalcogenide Glasses5.1 Introduction; 5.2 Chalcogenide Glass; 5.3 Photo-Induced Phenomena; 5.4 Sub-Gap Photo-Induced Phenomena; 5.4.1 Background; 5.4.2 Photo-Induced Bragg Grating; 5.4.3 Photo-Induced Persistent Self-Focusing Structure; 5.4.4 Photo-Induced Fluidity; 5.4.5 Giant Photoexpansion; 5.4.6 Spectral Light-Intensity Dependence; 5.5 Mechanism; 5.5.1 Temperature Rise; 5.5.2 Two-Photon Absorption; 5.5.3 Gap States and Microscopic Structure; 5.5.4 Refractive-Index Change; 5.5.5 Fluidity and Volume Expansion; 5.6 Summary; References
6 Photo-Induced Anisotropy in Chalcogenide Glassy Semiconductors6.1 Introduction; 6.2 Samples and Experimental Procedures; 6.3 Photo-Induced Optical Anisotropy; 6.3.1 Above-Bandgap Light Excitation; 6.3.2 Sub-Bandgap Light Excitation; 6.3.3 Super-Bandgap Light Excitation; 6.4 Photo-Induced Anisotropy of Other Properties of ChGS; 6.4.1 Polarization-Dependent Photocrystallization; 6.4.2 Polarization-Dependent Photodoping of ChGS Films by Silver; 6.4.3 Photo-Induced Anisotropy of Photoconductivity; 6.4.4 Anisotropic Opto-Mechanical Effect and Ionic Transport; 6.5 Conclusion; References
7 The Optomechanical Effect in Amorphous Chalcogenide Films
Record Nr. UNINA-9910144731903321
Kolobov Alexander V  
Weinheim, : [Cambridge], : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Photo-induced metastability in amorphous semiconductors [[electronic resource] /] / [edited by] Alexander V. Kolobov ; with a foreword of Kazunobu Tanaka
Photo-induced metastability in amorphous semiconductors [[electronic resource] /] / [edited by] Alexander V. Kolobov ; with a foreword of Kazunobu Tanaka
Autore Kolobov Alexander V
Pubbl/distr/stampa Weinheim, : [Cambridge], : Wiley-VCH, c2003
Descrizione fisica 1 online resource (438 p.)
Disciplina 541.22
621.38152
Altri autori (Persone) KolobovAlexander V
Soggetto topico Amorphous semiconductors
Chemical structure
ISBN 1-280-72298-3
9786610722983
3-527-60254-2
3-527-60866-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Photo-Induced Metastability in Amorphous Semiconductors; Preface; Introduction; Contents; List of Contributors; 1 Structure, Defects and Electronic Properties of Amorphous Semiconductors; 1.1 Structural States of Solids; 1.1.1 Ordered State; 1.1.2 Disordered (Non-Crystalline) State; 1.2 Atomic Scale Ordering in Crystalline and Non-Crystalline Solids; 1.2.1 Long-Range Order; 1.2.2 Short-Range Order; 1.2.3 Medium-Range Order; 1.3 Fundamental Problems of Structure of Non-Crystalline Semiconductors; 1.3.1 Tetrahedrally Bonded Amorphous Semiconductors
1.3.2 Amorphous Non-Tetrahedrally Bonded Semiconductors1.4 Defects in Non-Crystalline Solids; 1.4.1 Local Defects; 1.4.2 The Diffuse or Collective Defects (Extended Defects); 1.4.3 Chemical Defects; 1.4.4 Electronic-Structural Defects; 1.4.5 Macrodefects; 1.5 Electronic States in Amorphous Semiconductors; 1.5.1 Electronic States in Tetrahedrally Bonded Semiconductors; 1.5.2 Electronic States in Non-Tetrahedrally Bonded Semiconductors; References; 2 Photo-Induced Phenomena in Amorphous and Glassy Chalcogenides; 2.1 Introduction; 2.2 Photo-Induced Effects in Amorphous and Glassy Chalcogenides
2.2.1 Irreversible Photo-Induced Changes2.2.2 Reversible Photo-Induced Changes; 2.3 Applications; 2.4 Summary; References; 3 Short-, Medium- and Long-Range-Order Structural Transformations in Amorphous Semiconductors; 3.1 Introduction; 3.2 Short-Range-Order (SRO) Effects; 3.3 Medium-Range-Order (MRO) Effects; 3.4 Long-Range-Order (LRO) Effects; 3.5 Conclusion; References; 4 Dynamics of Photo-Induced Metastability in Amorphous Chalcogenides; 4.1 Introduction; 4.2 Light-Induced Metastable Defect (LIMD) Creation; 4.3 Photostructural Changes; 4.4 Discussion; 4.5 Conclusions; References
5 Sub-Gap Photo-Induced Phenomena in Chalcogenide Glasses5.1 Introduction; 5.2 Chalcogenide Glass; 5.3 Photo-Induced Phenomena; 5.4 Sub-Gap Photo-Induced Phenomena; 5.4.1 Background; 5.4.2 Photo-Induced Bragg Grating; 5.4.3 Photo-Induced Persistent Self-Focusing Structure; 5.4.4 Photo-Induced Fluidity; 5.4.5 Giant Photoexpansion; 5.4.6 Spectral Light-Intensity Dependence; 5.5 Mechanism; 5.5.1 Temperature Rise; 5.5.2 Two-Photon Absorption; 5.5.3 Gap States and Microscopic Structure; 5.5.4 Refractive-Index Change; 5.5.5 Fluidity and Volume Expansion; 5.6 Summary; References
6 Photo-Induced Anisotropy in Chalcogenide Glassy Semiconductors6.1 Introduction; 6.2 Samples and Experimental Procedures; 6.3 Photo-Induced Optical Anisotropy; 6.3.1 Above-Bandgap Light Excitation; 6.3.2 Sub-Bandgap Light Excitation; 6.3.3 Super-Bandgap Light Excitation; 6.4 Photo-Induced Anisotropy of Other Properties of ChGS; 6.4.1 Polarization-Dependent Photocrystallization; 6.4.2 Polarization-Dependent Photodoping of ChGS Films by Silver; 6.4.3 Photo-Induced Anisotropy of Photoconductivity; 6.4.4 Anisotropic Opto-Mechanical Effect and Ionic Transport; 6.5 Conclusion; References
7 The Optomechanical Effect in Amorphous Chalcogenide Films
Record Nr. UNINA-9910829886503321
Kolobov Alexander V  
Weinheim, : [Cambridge], : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Photo-induced metastability in amorphous semiconductors / / [edited by] Alexander V. Kolobov ; with a foreword of Kazunobu Tanaka
Photo-induced metastability in amorphous semiconductors / / [edited by] Alexander V. Kolobov ; with a foreword of Kazunobu Tanaka
Pubbl/distr/stampa Weinheim, : [Cambridge], : Wiley-VCH, c2003
Descrizione fisica 1 online resource (438 p.)
Disciplina 541.22
621.38152
Altri autori (Persone) KolobovAlexander V
Soggetto topico Amorphous semiconductors
Chemical structure
ISBN 9786610722983
9781280722981
1280722983
9783527602544
3527602542
9783527608669
3527608664
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Photo-Induced Metastability in Amorphous Semiconductors; Preface; Introduction; Contents; List of Contributors; 1 Structure, Defects and Electronic Properties of Amorphous Semiconductors; 1.1 Structural States of Solids; 1.1.1 Ordered State; 1.1.2 Disordered (Non-Crystalline) State; 1.2 Atomic Scale Ordering in Crystalline and Non-Crystalline Solids; 1.2.1 Long-Range Order; 1.2.2 Short-Range Order; 1.2.3 Medium-Range Order; 1.3 Fundamental Problems of Structure of Non-Crystalline Semiconductors; 1.3.1 Tetrahedrally Bonded Amorphous Semiconductors
1.3.2 Amorphous Non-Tetrahedrally Bonded Semiconductors1.4 Defects in Non-Crystalline Solids; 1.4.1 Local Defects; 1.4.2 The Diffuse or Collective Defects (Extended Defects); 1.4.3 Chemical Defects; 1.4.4 Electronic-Structural Defects; 1.4.5 Macrodefects; 1.5 Electronic States in Amorphous Semiconductors; 1.5.1 Electronic States in Tetrahedrally Bonded Semiconductors; 1.5.2 Electronic States in Non-Tetrahedrally Bonded Semiconductors; References; 2 Photo-Induced Phenomena in Amorphous and Glassy Chalcogenides; 2.1 Introduction; 2.2 Photo-Induced Effects in Amorphous and Glassy Chalcogenides
2.2.1 Irreversible Photo-Induced Changes2.2.2 Reversible Photo-Induced Changes; 2.3 Applications; 2.4 Summary; References; 3 Short-, Medium- and Long-Range-Order Structural Transformations in Amorphous Semiconductors; 3.1 Introduction; 3.2 Short-Range-Order (SRO) Effects; 3.3 Medium-Range-Order (MRO) Effects; 3.4 Long-Range-Order (LRO) Effects; 3.5 Conclusion; References; 4 Dynamics of Photo-Induced Metastability in Amorphous Chalcogenides; 4.1 Introduction; 4.2 Light-Induced Metastable Defect (LIMD) Creation; 4.3 Photostructural Changes; 4.4 Discussion; 4.5 Conclusions; References
5 Sub-Gap Photo-Induced Phenomena in Chalcogenide Glasses5.1 Introduction; 5.2 Chalcogenide Glass; 5.3 Photo-Induced Phenomena; 5.4 Sub-Gap Photo-Induced Phenomena; 5.4.1 Background; 5.4.2 Photo-Induced Bragg Grating; 5.4.3 Photo-Induced Persistent Self-Focusing Structure; 5.4.4 Photo-Induced Fluidity; 5.4.5 Giant Photoexpansion; 5.4.6 Spectral Light-Intensity Dependence; 5.5 Mechanism; 5.5.1 Temperature Rise; 5.5.2 Two-Photon Absorption; 5.5.3 Gap States and Microscopic Structure; 5.5.4 Refractive-Index Change; 5.5.5 Fluidity and Volume Expansion; 5.6 Summary; References
6 Photo-Induced Anisotropy in Chalcogenide Glassy Semiconductors6.1 Introduction; 6.2 Samples and Experimental Procedures; 6.3 Photo-Induced Optical Anisotropy; 6.3.1 Above-Bandgap Light Excitation; 6.3.2 Sub-Bandgap Light Excitation; 6.3.3 Super-Bandgap Light Excitation; 6.4 Photo-Induced Anisotropy of Other Properties of ChGS; 6.4.1 Polarization-Dependent Photocrystallization; 6.4.2 Polarization-Dependent Photodoping of ChGS Films by Silver; 6.4.3 Photo-Induced Anisotropy of Photoconductivity; 6.4.4 Anisotropic Opto-Mechanical Effect and Ionic Transport; 6.5 Conclusion; References
7 The Optomechanical Effect in Amorphous Chalcogenide Films
Record Nr. UNINA-9911018927903321
Weinheim, : [Cambridge], : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Proteomic and genomic analysis of cardiovascular disease [[electronic resource] /] / edited by Jennifer E. Van Eyk and Michael J. Dunn
Proteomic and genomic analysis of cardiovascular disease [[electronic resource] /] / edited by Jennifer E. Van Eyk and Michael J. Dunn
Pubbl/distr/stampa Weinheim, : [Cambridge], : Wiley-VCH, c2003
Descrizione fisica 1 online resource (426 p.)
Disciplina 572.6
616.1/042
616.1042
Altri autori (Persone) Van EykJennifer E. <1959->
DunnMichael J. <1936->
Soggetto topico Cardiovascular system - Diseases - Genetic aspects
Proteomics
Soggetto genere / forma Electronic books.
ISBN 1-280-52054-X
9786610520541
3-527-60545-2
3-527-60152-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Proteomic and Genomic Analysis of Cardiovascular Disease; Preface; Contents; List of Contributors; Abbreviations; Section 1 Genomics; 1 Large Scale Expression Profiling in Cardiovascular Disease Using Microarrays: Prospects and Pitfalls; 1.1 DNA Microarray Technologies; 1.1.1 cDNA Microarrays or Oligonucleotide Arrays?; 1.1.2 Designing Meaningful Experiments; 1.2 Computational Analysis of Microarray Data; 1.2.1 Raw Data Analysis; 1.2.2 Comparing Expression Data; 1.2.3 Clustering Algorithms; 1.2.4 Data Sharing; 1.3 Potential Use of this Technology in Understanding Complex Heart Disease
1.4 Acknowledgements1.5 References; 2 Global Genomic Analyses of Cardiovascular Disease: A Potential Map or Blind Alley?; 2.1 Blindly Searching for Structure-Function; 2.2 The Starting Line: Garbage In - Garbage Out?; 2.3 Is the Mouse a Valid Model for Human-Based Disease Transcriptome Studies?; 2.4 Arrays and Cardiovascular Disease; 2.5 Filtering the Transcriptome: Enhancing the Value; 2.6 Concluding Remarks; 2.7 References; 3 Heart Failure: A Genomics Approach; 3.1 Overview of Heart Failure; 3.2 Pathophysiology of Heart Failure; 3.3 Genomic Approach to Heart Failure; 3.4 Conclusion
3.5 Acknowledgements3.6 References; 4 Principles of cDNA Microarrays as Applied in Heart Failure Research; 4.1 The Clinical Problem; 4.2 The Need for a New Paradigm; 4.3 The Potential Role of the Microarray; 4.4 Strengths of Microarray Technology; 4.5 Caveats of Using the Microarray Technology; 4.6 Experimental Design; 4.7 Tissue Preparation and Preservation; 4.8 RNA Isolation; 4.9 RNA Amplification; 4.10 Probe Labeling; 4.11 Data Analysis and Bioinformatics; 4.12 Application: New Classification of Disease; 4.13 Application: Pathogenesis of Disease
4.14 Application: Early Disease Markers and Prognosis4.15 Application: Therapeutic Insights; 4.16 Acknowledgements; 4.17 References; 5 Gene Profiling in the Heart by Subtractive Hybridization; 5.1 Strategies and Limitations of Genome Profiling; 5.1.1 The Biological Problem; 5.1.2 The Model; 5.1.3 The Technological Approach; 5.2 Analyzing Gene Expression by Subtractive Hybridization; 5.2.1 Methodology; 5.2.2 Advantages and Disadvantages; 5.3 Genomics of Myocardial Ischemia; 5.4 Subtractive Hybridization of Myocardial Ischemia; 5.4.1 Myocardial Stunning
5.4.2 Genomic Profile of Myocardial Stunning5.4.3 Chasing Novel Genes; 5.5 Summary; 5.6 Acknowledgements; 5.7 References; 6 DNA Microarray Gene Profiling: A Tool for the Elucidation of Cardioprotective Genes; 6.1 Introduction; 6.2 Candidates for Cardioprotective Genes and Possible Mechanism(s) of Protection; 6.2.1 Candidate Genes Involved in Cardioprotection; 6.2.2 Potential Mechanisms of Cardioprotection; 6.3 Is There a Common Set of Cardioprotective Genes?; 6.4 Effects of Long-term Activation and Dosage of Cardioprotective Genes; 6.5 Approaches to Identify Genes Involved in Cardioprotection
6.5.1 Preconditioning
Record Nr. UNINA-9910146239203321
Weinheim, : [Cambridge], : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Proteomic and genomic analysis of cardiovascular disease [[electronic resource] /] / edited by Jennifer E. Van Eyk and Michael J. Dunn
Proteomic and genomic analysis of cardiovascular disease [[electronic resource] /] / edited by Jennifer E. Van Eyk and Michael J. Dunn
Pubbl/distr/stampa Weinheim, : [Cambridge], : Wiley-VCH, c2003
Descrizione fisica 1 online resource (426 p.)
Disciplina 572.6
616.1/042
616.1042
Altri autori (Persone) Van EykJennifer E. <1959->
DunnMichael J. <1936->
Soggetto topico Cardiovascular system - Diseases - Genetic aspects
Proteomics
ISBN 1-280-52054-X
9786610520541
3-527-60545-2
3-527-60152-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Proteomic and Genomic Analysis of Cardiovascular Disease; Preface; Contents; List of Contributors; Abbreviations; Section 1 Genomics; 1 Large Scale Expression Profiling in Cardiovascular Disease Using Microarrays: Prospects and Pitfalls; 1.1 DNA Microarray Technologies; 1.1.1 cDNA Microarrays or Oligonucleotide Arrays?; 1.1.2 Designing Meaningful Experiments; 1.2 Computational Analysis of Microarray Data; 1.2.1 Raw Data Analysis; 1.2.2 Comparing Expression Data; 1.2.3 Clustering Algorithms; 1.2.4 Data Sharing; 1.3 Potential Use of this Technology in Understanding Complex Heart Disease
1.4 Acknowledgements1.5 References; 2 Global Genomic Analyses of Cardiovascular Disease: A Potential Map or Blind Alley?; 2.1 Blindly Searching for Structure-Function; 2.2 The Starting Line: Garbage In - Garbage Out?; 2.3 Is the Mouse a Valid Model for Human-Based Disease Transcriptome Studies?; 2.4 Arrays and Cardiovascular Disease; 2.5 Filtering the Transcriptome: Enhancing the Value; 2.6 Concluding Remarks; 2.7 References; 3 Heart Failure: A Genomics Approach; 3.1 Overview of Heart Failure; 3.2 Pathophysiology of Heart Failure; 3.3 Genomic Approach to Heart Failure; 3.4 Conclusion
3.5 Acknowledgements3.6 References; 4 Principles of cDNA Microarrays as Applied in Heart Failure Research; 4.1 The Clinical Problem; 4.2 The Need for a New Paradigm; 4.3 The Potential Role of the Microarray; 4.4 Strengths of Microarray Technology; 4.5 Caveats of Using the Microarray Technology; 4.6 Experimental Design; 4.7 Tissue Preparation and Preservation; 4.8 RNA Isolation; 4.9 RNA Amplification; 4.10 Probe Labeling; 4.11 Data Analysis and Bioinformatics; 4.12 Application: New Classification of Disease; 4.13 Application: Pathogenesis of Disease
4.14 Application: Early Disease Markers and Prognosis4.15 Application: Therapeutic Insights; 4.16 Acknowledgements; 4.17 References; 5 Gene Profiling in the Heart by Subtractive Hybridization; 5.1 Strategies and Limitations of Genome Profiling; 5.1.1 The Biological Problem; 5.1.2 The Model; 5.1.3 The Technological Approach; 5.2 Analyzing Gene Expression by Subtractive Hybridization; 5.2.1 Methodology; 5.2.2 Advantages and Disadvantages; 5.3 Genomics of Myocardial Ischemia; 5.4 Subtractive Hybridization of Myocardial Ischemia; 5.4.1 Myocardial Stunning
5.4.2 Genomic Profile of Myocardial Stunning5.4.3 Chasing Novel Genes; 5.5 Summary; 5.6 Acknowledgements; 5.7 References; 6 DNA Microarray Gene Profiling: A Tool for the Elucidation of Cardioprotective Genes; 6.1 Introduction; 6.2 Candidates for Cardioprotective Genes and Possible Mechanism(s) of Protection; 6.2.1 Candidate Genes Involved in Cardioprotection; 6.2.2 Potential Mechanisms of Cardioprotection; 6.3 Is There a Common Set of Cardioprotective Genes?; 6.4 Effects of Long-term Activation and Dosage of Cardioprotective Genes; 6.5 Approaches to Identify Genes Involved in Cardioprotection
6.5.1 Preconditioning
Record Nr. UNINA-9910830464203321
Weinheim, : [Cambridge], : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Proteomic and genomic analysis of cardiovascular disease / / edited by Jennifer E. Van Eyk and Michael J. Dunn
Proteomic and genomic analysis of cardiovascular disease / / edited by Jennifer E. Van Eyk and Michael J. Dunn
Pubbl/distr/stampa Weinheim, : [Cambridge], : Wiley-VCH, c2003
Descrizione fisica 1 online resource (426 p.)
Disciplina 572.6
616.1/042
616.1042
Altri autori (Persone) Van EykJennifer E. <1959->
DunnMichael J. <1936->
Soggetto topico Cardiovascular system - Diseases - Genetic aspects
Proteomics
ISBN 9786610520541
9781280520549
128052054X
9783527605453
3527605452
9783527601523
352760152X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Proteomic and Genomic Analysis of Cardiovascular Disease; Preface; Contents; List of Contributors; Abbreviations; Section 1 Genomics; 1 Large Scale Expression Profiling in Cardiovascular Disease Using Microarrays: Prospects and Pitfalls; 1.1 DNA Microarray Technologies; 1.1.1 cDNA Microarrays or Oligonucleotide Arrays?; 1.1.2 Designing Meaningful Experiments; 1.2 Computational Analysis of Microarray Data; 1.2.1 Raw Data Analysis; 1.2.2 Comparing Expression Data; 1.2.3 Clustering Algorithms; 1.2.4 Data Sharing; 1.3 Potential Use of this Technology in Understanding Complex Heart Disease
1.4 Acknowledgements1.5 References; 2 Global Genomic Analyses of Cardiovascular Disease: A Potential Map or Blind Alley?; 2.1 Blindly Searching for Structure-Function; 2.2 The Starting Line: Garbage In - Garbage Out?; 2.3 Is the Mouse a Valid Model for Human-Based Disease Transcriptome Studies?; 2.4 Arrays and Cardiovascular Disease; 2.5 Filtering the Transcriptome: Enhancing the Value; 2.6 Concluding Remarks; 2.7 References; 3 Heart Failure: A Genomics Approach; 3.1 Overview of Heart Failure; 3.2 Pathophysiology of Heart Failure; 3.3 Genomic Approach to Heart Failure; 3.4 Conclusion
3.5 Acknowledgements3.6 References; 4 Principles of cDNA Microarrays as Applied in Heart Failure Research; 4.1 The Clinical Problem; 4.2 The Need for a New Paradigm; 4.3 The Potential Role of the Microarray; 4.4 Strengths of Microarray Technology; 4.5 Caveats of Using the Microarray Technology; 4.6 Experimental Design; 4.7 Tissue Preparation and Preservation; 4.8 RNA Isolation; 4.9 RNA Amplification; 4.10 Probe Labeling; 4.11 Data Analysis and Bioinformatics; 4.12 Application: New Classification of Disease; 4.13 Application: Pathogenesis of Disease
4.14 Application: Early Disease Markers and Prognosis4.15 Application: Therapeutic Insights; 4.16 Acknowledgements; 4.17 References; 5 Gene Profiling in the Heart by Subtractive Hybridization; 5.1 Strategies and Limitations of Genome Profiling; 5.1.1 The Biological Problem; 5.1.2 The Model; 5.1.3 The Technological Approach; 5.2 Analyzing Gene Expression by Subtractive Hybridization; 5.2.1 Methodology; 5.2.2 Advantages and Disadvantages; 5.3 Genomics of Myocardial Ischemia; 5.4 Subtractive Hybridization of Myocardial Ischemia; 5.4.1 Myocardial Stunning
5.4.2 Genomic Profile of Myocardial Stunning5.4.3 Chasing Novel Genes; 5.5 Summary; 5.6 Acknowledgements; 5.7 References; 6 DNA Microarray Gene Profiling: A Tool for the Elucidation of Cardioprotective Genes; 6.1 Introduction; 6.2 Candidates for Cardioprotective Genes and Possible Mechanism(s) of Protection; 6.2.1 Candidate Genes Involved in Cardioprotection; 6.2.2 Potential Mechanisms of Cardioprotection; 6.3 Is There a Common Set of Cardioprotective Genes?; 6.4 Effects of Long-term Activation and Dosage of Cardioprotective Genes; 6.5 Approaches to Identify Genes Involved in Cardioprotection
6.5.1 Preconditioning
Record Nr. UNINA-9911019629503321
Weinheim, : [Cambridge], : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui