Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Molecular and quantitative animal genetics / / edited by Hasan Khatib
| Molecular and quantitative animal genetics / / edited by Hasan Khatib |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , c2015 |
| Descrizione fisica | 1 online resource (331 pages) : illustrations (some color) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property Animals Genetics Molecular Biology |
| ISBN |
1118677323
9781118677322 |
| Classificazione |
481.39
467 QH 432 591.3/5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Record Nr. | UNINA-9910796080803321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , c2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular and quantitative animal genetics / / edited by Hasan Khatib
| Molecular and quantitative animal genetics / / edited by Hasan Khatib |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , c2015 |
| Descrizione fisica | 1 online resource (331 pages) : illustrations (some color) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property Animals Genetics Molecular Biology |
| ISBN |
1118677323
9781118677322 |
| Classificazione |
481.39
467 QH 432 591.3/5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Nota di contenuto |
Cover -- Title page -- Copyright page -- Contents -- Contributors -- Manuscript Reviewers -- Preface -- 1: Decoding and Encoding the "DNA" of Teaching and Learning in College Classrooms -- Introduction -- Teaching and learning: definitions -- Understanding learning -- Research in learning -- Transferable and life-long learning skills and aptitudes -- Understanding teaching -- Research in teaching -- Implications for classroom design in the twenty-first century -- Architecture of an effective classroom -- Instructional features for life-long learning -- Toward an active learning classroom -- Final thoughts -- References -- Review questions -- Section 1: Quantitative and Population Genetics -- 2: Mating Systems: Inbreeding and Inbreeding Depression -- Introduction -- Inbreeding -- Genetic defects -- Inbreeding depression -- Cause of inbreeding depression -- Quantifying inbreeding -- Inbreeding coefficient -- Inbreeding coefficient formula -- Calculating inbreeding coefficients -- Genomics and inbreeding -- Summary -- Further reading -- References -- Review questions -- 3: Genomic Selection, Inbreeding, and Crossbreeding in Dairy Cattle -- Introduction -- Genomic selection -- Genotyping tools -- Parentage verification and discovery -- Individual genes with large effects -- Genotype imputation -- Genome-enabled breeding value prediction -- Applications of genomics to selection of elite breeding stock -- Applications of genomics to improvement of replacement heifers on commercial farms -- Crossbreeding -- Breed characteristics and complementarity -- Heterosis and crossbreeding systems -- Experiments and field results -- Inbreeding and genetic defects -- Relationships, inbreeding, and effective population size -- Inherited defects -- Inbreeding depression for quantitative traits -- Managing inbreeding and genetic diversity -- Summary -- References.
Review questions -- 4: Basic Genetic Model for Quantitative Traits -- Introduction -- Quantitative traits -- Expected value and variance: the normal distribution -- Basic genetic model for quantitative traits -- Heritability and selection -- Predicting rate of genetic change from selection -- Further reading -- References -- 5: Heritability and Repeatability -- Introduction -- Heritability -- Estimation of heritability and variance components -- Prediction of breeding values and of response to selection -- Repeatability -- References -- 6: Applications of Statistics in Quantitative Traits -- Population and sample -- Parameter and statistics -- Descriptive statistics -- Types of variables -- Descriptive statistics categorical (qualitative) data -- Descriptive statistics for quantitative variables -- Comparing of arithmetic mean, median, and mode -- Measures of dispersion -- Graphically examining the distribution of the data -- Graphical presentation of categorical data -- Graphical presentation of quantitative data -- Normal distribution -- Area under the curve -- Standard normal distributions -- Exploring relationships between variables -- Covariance -- Correlation -- Regression -- Summary -- Population and sample -- Descriptive statistics -- Graphically examining the distribution of the data -- Normal distribution -- Exploring relationships between variables -- Appendix 6.1 -- Further reading -- References -- Review questions -- Section 2: Applications of Genetics and Genomics to Livestock and Companion Animal Species -- 7: Genetic Improvement of Beef Cattle -- Introduction -- Single trait selection -- National cattle evaluation -- Multiple trait selection -- Summary -- Further reading -- References -- 8: Genetic Improvement in Sheep through Selection -- Products from sheep -- Selection among breeds. Selection within a breed or population and the Key Equation -- Adjustment for environmental effects -- Phenotypic selection -- Estimated breeding values (EBV) -- Using multiple sources of information -- Genetic correlations -- Selection intensity -- Generation interval (L) -- Predicting progress from selection -- National genetic improvement programs -- Summary -- Further reading -- References -- Review questions -- 9: Genetic Improvement Programs for Dairy Cattle -- Introduction -- Data collection infrastructure -- Milk recording -- Pedigree information -- Type classification -- Health, fertility, calving ability, and longevity data -- Progeny testing and AI programs -- Estimation of breeding values -- Pre-adjustment for known environmental effects -- Contemporary groups -- Animal model genetic evaluations -- Four paths of selection -- Selection for increased productivity -- Milk yield -- Component percentages and cheese yield -- Maintenance costs and efficiency of milk production -- Net merit index (income portion) -- Selection for functional traits -- Calving performance -- Male and female fertility -- Udder health and mastitis -- Mobility -- Frame size and body condition -- Culling and longevity -- Net merit index (expense portion) -- Sire selection -- Selection index or independent culling levels? -- Reliability and management of risk -- Gender-enhanced semen -- Summary -- Further reading -- References -- Review questions -- 10: Genetic and Genomic Improvement of Pigs -- Introduction -- Domestication of swine and breed development -- Methods of selection and mating systems -- Traits of economic importance -- Development of molecular genetic approaches -- QTL, candidate genes, and genetic improvement -- Sequencing the pig genome -- Genomic selection -- Databases -- Cloning, transgenics, and breeding pigs as biological models. Future applications to genetic improvement -- Acknowledgments -- Further reading -- References -- Review questions -- 11: Equine Genetics -- Color -- Introduction -- Base colors -- Modifiers to base colors -- Other modifications -- White markings -- Paint/pinto patterns -- Genetic defects -- Introduction -- Dominant disorders -- Recessive disorders -- The genetics of health -- Inbreeding and relationship -- Inbreeding -- Relationship -- Selection and improvement -- Quantitative genetics -- Genetic improvement -- Genetic evaluation -- New technologies -- Cloning -- Equine genomics -- Further reading -- References -- Review questions -- 12: Genetics and Genomics of the Domestic Dog -- Introduction to canine research -- Domestication -- Breeding -- A model organism -- Genetic testing -- The dog genome -- Genomic tools -- Whole genome sequence -- Genome structure -- Uncovering the genetic basis of phenotypes -- Candidate gene approaches -- Genome-wide approaches -- Quantitative traits -- Future challenges -- Behavior -- Cancer -- Summary -- Further reading -- References -- Review questions -- 13: The Sheep Genome -- Investment in sheep genome research -- Overview of the sheep genome -- Genomic resources in sheep -- Physical map -- Linkage maps -- Radiation hybrid maps -- SNP arrays -- BAC library and end sequences -- Whole genome reference sequence -- Whole genome assembly -- Application of genomic resources -- Summary -- References -- Review questions -- 14: Goat Genetics and Genomic Progress -- Introduction -- Genetics and goat domestication -- Taxonomy -- Goat chromosome number and structure -- Patterns of inheritance -- Mendelian traits and exceptions -- Quantitative trail loci (QTL) -- Progress in goat genomics -- Biotechnologies and goat genetics -- Cloning -- Transgenic animals -- Summary -- Further reading -- Review questions. Section 3: Molecular Genetics of Production and Economically Important Traits -- 15: Bioinformatics in Animal Genetics -- Introduction -- Bioinformatics and animal genetics -- The importance of bioinformatics in genomics research -- Genome sequencing -- Alignment -- Genome assembly -- Annotation -- Gene expression -- Microarrays -- RNA-Seq -- Gene regulation -- Epigenetics -- Genomic data manipulation -- R language -- Bioconductor -- Web-based tools -- Bioinformatics perspectives in animal genetics -- References -- Review questions -- 16: Genome-wide Association Studies in Pedigreed Populations -- Introduction -- Experimental designs -- Genotyping and linkage disequilibrium -- Quality control -- The statistical analysis -- Significance testing -- Inspection of GWAS results -- Dealing with population structure -- Methods and tools for GWAS in pedigreed populations -- PLINK -- TASSEL -- EMMA/EMMAX -- GenABEL -- Things to remember about analysis -- What did we miss? -- Acknowledgments -- References -- 17: Molecular Genetics Techniques and High Throughput Technologies -- Central dogma of molecular biology -- Review of properties of nucleic acids -- Purification of nucleic acids from cells -- Determining the quantity and purity of nucleic acids -- UV spectrophotometry -- Fluorometry -- Gel electrophoresis -- Polymerase chain reaction (PCR) -- Determining the identity of DNA -- Chain termination method -- Restriction Fragment Length Polymorphism (RFLP) for variant genotyping -- Concept of parallelization and high throughput assays -- Microarray technology -- Array fabrication -- Labeling RNA -- Hybridization of cRNA -- Quantitation of hybridization -- Other applications of microarrays -- Next generation sequencing technology -- Introduction to next generation sequencing -- Unique challenges of next generation sequencing. Applications of next generation sequencing technologies. |
| Record Nr. | UNINA-9910813941103321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , c2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||