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Heterocyclic chemistry in drug discovery / / edited by Jie Jack Li
| Heterocyclic chemistry in drug discovery / / edited by Jie Jack Li |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, 2013 |
| Descrizione fisica | 1 online resource (722 p.) |
| Disciplina | 615.1/9 |
| Altri autori (Persone) | LiJie Jack |
| Collana | New York Academy of Sciences |
| Soggetto topico |
Drug development
Heterocyclic compounds |
| ISBN |
9781118354445
1118354443 9781118509494 1118509498 9781118354438 1118354435 9781118354421 1118354427 |
| Classificazione |
499.1
499.3 QD 400 615.1/9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 2. Pyrroles -- 3. Indoles -- 4. Furans, benzofurans, thiophenes, and benzothiophenes -- 5. Pyrazoles, pyrazolones, and indazoles -- 6. Oxazoles, isoxazoles, and oxazolidinones -- 7. Thiazoles and benzothiazoles -- 8. Imidazoles and benzimidazoles -- 9. Triazoles and tetrazoles -- 10. Pyridines -- 11. Quinolines and isoquinolines -- 12. Pyrazines and quinoxalines -- 13. Pyrimidines -- 14. Quinazolines and quinazolones. |
| Record Nr. | UNINA-9910959010103321 |
| Hoboken, N.J., : Wiley, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to Pharmaceutical Chemical Analysis
| Introduction to Pharmaceutical Chemical Analysis |
| Pubbl/distr/stampa | Hoboken, : Wiley, 2011 |
| Descrizione fisica | 1 online resource (512 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
Pedersen-BjergaardStig
RasmussenKnut |
| Soggetto topico |
Drugs - Analysis
Pharmaceutical chemistry |
| ISBN |
9786613306791
9781283306799 1283306794 9781119953647 1119953642 9781119953609 111995360X |
| Classificazione |
499.33
QV 55 615.1/9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Introduction to Pharmaceutical Chemical Analysis; Table of Contents; Preface; 1 Introduction to Pharmaceutical Analysis; 1.1 Applications and Definitions; 1.2 The Life of Medicines; 1.3 The Quality of Medical Products; 1.4 Summary; 2 International Pharmacopoeias, Regulations and Guidelines; 2.1 Overview of Legislation; 2.2 Legislation and Regulations for Industrial Production; 2.3 Life Time of Drugs and Drug Substances; 2.4 Pharmacopoeias; 2.5 International Harmonization; 2.5.1 International Conference on Harmonization; 2.5.2 Pharmacopoeial Discussion Group
2.6 Legislation and Regulations for Pharmacy Production2.7 Summary; 3 Fundamental Chemical Properties, Buffers and pH; 3.1 pH and pKa; 3.2 Partition; 3.3 Stereochemistry; 3.4 Stability Testing; 3.5 Summary; 4 Fundamentals of Pharmaceutical Analysis; 4.1 What is a Pharmaceutical (Chemical) Analysis?; 4.2 How to Specify Quantities and Concentrations?; 4.3 Basic Laboratory Equipment; 4.3.1 The Analytical Balance; 4.3.2 Pipettes; 4.3.3 Volumetric Flasks; 4.3.4 Burettes; 4.4 How to Make Solutions and Dilutions; 4.5 Calibration of Analytical Methods; 4.6 Errors, Accuracy, and Precision 4.6.1 Systematic and Random Errors4.6.2 Accuracy and Precision; 4.7 Statistics; 4.7.1 Mean Value and Standard Deviation; 4.7.2 Confidence Intervals; 4.7.3 Comparison of Means with a t-Test; 4.7.4 Q-Test to Reject Outliers; 4.7.5 Linear Regression with the Method of Least Squares; 4.7.6 How to Present an Analytical Result; 4.8 Some Words and Concepts; 4.8.1 Analysis and Determination; 4.8.2 Sample Replicates and Measuring Replicates; 4.8.3 Interference; 4.8.4 Blind Samples; 5 Titrimetric Methods; 5.1 Introduction; 5.2 Acid-Base Titrations; 5.3 Acid-Base Titrations in Non-Aqueous Media 5.4 Redox Titrations5.5 Other Principles of Titration; 5.6 Summary; 6 Introduction to Spectroscopic Methods; 6.1 Electromagnetic Radiation; 6.2 Molecules and Electromagnetic Radiation; 6.3 Atoms and Electromagnetic Radiation; 6.4 Summary; 7 UV Spectrophotometry; 7.1 Principle of Quantitative Determination; 7.2 Principle of Identification; 7.3 Which Substances Have Strong UV Absorbance?; 7.4 Instrumentation; 7.5 Practical Work and Method Development; 7.6 Areas of Usage and Performance; 7.7 System Testing; 7.8 Summary; 8 IR Spectrophotometry; 8.1 IR Spectrophotometry; 8.2 Instrumentation 8.3 Scope8.4 Instrument Calibration; 8.5 NIR Spectrophotometry; 8.6 Applications; 8.7 Summary; 9 Atomic Spectrometry; 9.1 Atomic Absorption Spectrometry; 9.2 Instrumentation; 9.3 Applications and Performance; 9.4 Practical Work and Method Development; 9.5 Atomic Emission Spectrometry; 9.6 Instrumentation; 9.7 Summary; 10 Chromatography; 10.1 General Principles; 10.2 Retention; 10.3 Column Efficiency; 10.4 Selectivity; 10.5 Peak Symmetry; 10.6 Resolution; 10.7 Chromatographic Techniques; 10.8 Summary; 11 Chromatographic Separation Principles; 11.1 General Introduction 11.2 Normal Phase Chromatography |
| Record Nr. | UNINA-9910139569303321 |
| Hoboken, : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||