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Conservation and the genetics of populations [[electronic resource] /] / Fred W. Allendorf, Gordon Luikart, Sally N. Aitken ; with illustrations by Agostinho Antunes
| Conservation and the genetics of populations [[electronic resource] /] / Fred W. Allendorf, Gordon Luikart, Sally N. Aitken ; with illustrations by Agostinho Antunes |
| Autore | Allendorf Frederick William |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, : John Wiley & Sons, 2012 |
| Descrizione fisica | 1 online resource (630 p.) |
| Disciplina | 333.95/16 |
| Altri autori (Persone) |
LuikartGordon
AitkenSally N |
| Collana | New York Academy of Sciences |
| Soggetto topico |
Biodiversity conservation
Population genetics Evolutionary genetics |
| ISBN |
1-118-40857-8
1-283-64455-X 1-118-40856-X |
| Classificazione |
467
333.95/16 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title page; Copyright page; Contents; Guest Box authors; Preface; Preface to the first edition; List of symbols; PART I: Introduction; CHAPTER 1: Introduction; 1.1 Genetics and Civilization; 1.2 What Should We Conserve?; 1.2.1 Phylogenetic diversity; 1.2.2 Populations, species, or ecosystems?; 1.3 How Should We Conserve Biodiversity?; 1.4 Applications of Genetics to Conservation; 1.5 The Future; Guest Box 1: L. Scott Mills and Michael E. Soulé, The role of genetics in conservation; CHAPTER 2: Phenotypic variation in natural populations; 2.1 Color Pattern; 2.2 Morphology; 2.3 Behavior
2.4 Phenology2.5 Differences Among Populations; 2.5.1 Countergradient variation; 2.6 Nongenetic Inheritance; Guest Box 2: Chris J. Foote, Looks can be deceiving: countergradient variation in secondary sexual color in sympatric morphs of sockeye salmon; CHAPTER 3: Genetic variation in natural populations: chromosomes and proteins; 3.1 Chromosomes; 3.1.1 Karyotypes; 3.1.2 Sex chromosomes; 3.1.3 Polyploidy; 3.1.4 Numbers of chromosomes; 3.1.5 Supernumerary chromosomes; 3.1.6 Chromosomal size; 3.1.7 Inversions; 3.1.8 Translocations; 3.1.9 Chromosomal variation and conservation 3.2 Protein Electrophoresis3.2.1 Strengths and limitations of protein electrophoresis; 3.3 Genetic Variation within Natural Populations; 3.3.1 Data from natural populations; 3.4 Genetic Divergence Among Populations; Guest Box 3: E. M. Tuttle, Chromosomal polymorphism in the white-throated sparrow; CHAPTER 4: Genetic variation in natural populations: DNA; 4.1 Mitochondrial and Chloroplast Organelle DNA; 4.1.1 Restriction endonucleases and RFLPs; 4.1.2 Polymerase chain reaction; 4.2 Single-Copy Nuclear Loci; 4.2.1 Microsatellites; 4.2.2 PCR of protein-coding loci 4.2.3 Single nucleotide polymorphisms4.2.4 Sex-linked markers; 4.3 Multiple Locus Techniques; 4.3.1 Minisatellites; 4.3.2 AFLPs and ISSRs; 4.4 Genomic Tools and Markers; 4.4.1 High-throughput sequencing; 4.4.2 Inferences from sequence data; 4.4.3 EST sequencing applications; 4.4.4 SNP discovery and genotyping by sequencing; 4.5 Transcriptomics; 4.6 Other 'Omics' and The Future; 4.6.1 Metagenomics; Guest Box 4: Louis Bernatchez Rapid evolutionary changes of gene expression in domesticated Atlantic salmon and its consequences for the conservation of wild populations PART II: Mechanisms of Evolutionary ChangeCHAPTER 5: Random mating populations: Hardy-Weinberg principle; 5.1 Hardy-Weinberg Principle; 5.2 Hardy-Weinberg Proportions; 5.3 Testing for Hardy-Weinberg Proportions; 5.3.1 Small sample sizes or many alleles; 5.3.2 Multiple simultaneous tests; 5.4 Estimation of Allele Frequencies; 5.4.1 Recessive alleles; 5.4.2 Null alleles; 5.5 Sex-Linked Loci; 5.5.1 Pseudoautosomal inheritance; 5.6 Estimation of Genetic Variation; 5.6.1 Heterozygosity; 5.6.2 Allelic richness; 5.6.3 Proportion of polymorphic loci Guest Box 5: Paul Sunnucks and Birgita D. Hansen, Null alleles and Bonferroni 'abuse': treasure your exceptions (and so get it right for Leadbeater's possum) |
| Record Nr. | UNINA-9910786001203321 |
Allendorf Frederick William
|
||
| Chichester, West Sussex, : John Wiley & Sons, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Conservation and the genetics of populations / / Fred W. Allendorf, Gordon Luikart, Sally N. Aitken ; with illustrations by Agostinho Antunes
| Conservation and the genetics of populations / / Fred W. Allendorf, Gordon Luikart, Sally N. Aitken ; with illustrations by Agostinho Antunes |
| Autore | Allendorf Frederick William |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, : John Wiley & Sons, 2012 |
| Descrizione fisica | 1 online resource (630 p.) |
| Disciplina | 333.95/16 |
| Altri autori (Persone) |
AitkenSally N
LuikartGordon |
| Collana | New York Academy of Sciences |
| Soggetto topico |
Biodiversity conservation
Evolutionary genetics Population genetics |
| ISBN |
1-118-40857-8
1-283-64455-X 1-118-40856-X |
| Classificazione |
467
333.95/16 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title page; Copyright page; Contents; Guest Box authors; Preface; Preface to the first edition; List of symbols; PART I: Introduction; CHAPTER 1: Introduction; 1.1 Genetics and Civilization; 1.2 What Should We Conserve?; 1.2.1 Phylogenetic diversity; 1.2.2 Populations, species, or ecosystems?; 1.3 How Should We Conserve Biodiversity?; 1.4 Applications of Genetics to Conservation; 1.5 The Future; Guest Box 1: L. Scott Mills and Michael E. Soulé, The role of genetics in conservation; CHAPTER 2: Phenotypic variation in natural populations; 2.1 Color Pattern; 2.2 Morphology; 2.3 Behavior
2.4 Phenology2.5 Differences Among Populations; 2.5.1 Countergradient variation; 2.6 Nongenetic Inheritance; Guest Box 2: Chris J. Foote, Looks can be deceiving: countergradient variation in secondary sexual color in sympatric morphs of sockeye salmon; CHAPTER 3: Genetic variation in natural populations: chromosomes and proteins; 3.1 Chromosomes; 3.1.1 Karyotypes; 3.1.2 Sex chromosomes; 3.1.3 Polyploidy; 3.1.4 Numbers of chromosomes; 3.1.5 Supernumerary chromosomes; 3.1.6 Chromosomal size; 3.1.7 Inversions; 3.1.8 Translocations; 3.1.9 Chromosomal variation and conservation 3.2 Protein Electrophoresis3.2.1 Strengths and limitations of protein electrophoresis; 3.3 Genetic Variation within Natural Populations; 3.3.1 Data from natural populations; 3.4 Genetic Divergence Among Populations; Guest Box 3: E. M. Tuttle, Chromosomal polymorphism in the white-throated sparrow; CHAPTER 4: Genetic variation in natural populations: DNA; 4.1 Mitochondrial and Chloroplast Organelle DNA; 4.1.1 Restriction endonucleases and RFLPs; 4.1.2 Polymerase chain reaction; 4.2 Single-Copy Nuclear Loci; 4.2.1 Microsatellites; 4.2.2 PCR of protein-coding loci 4.2.3 Single nucleotide polymorphisms4.2.4 Sex-linked markers; 4.3 Multiple Locus Techniques; 4.3.1 Minisatellites; 4.3.2 AFLPs and ISSRs; 4.4 Genomic Tools and Markers; 4.4.1 High-throughput sequencing; 4.4.2 Inferences from sequence data; 4.4.3 EST sequencing applications; 4.4.4 SNP discovery and genotyping by sequencing; 4.5 Transcriptomics; 4.6 Other 'Omics' and The Future; 4.6.1 Metagenomics; Guest Box 4: Louis Bernatchez Rapid evolutionary changes of gene expression in domesticated Atlantic salmon and its consequences for the conservation of wild populations PART II: Mechanisms of Evolutionary ChangeCHAPTER 5: Random mating populations: Hardy-Weinberg principle; 5.1 Hardy-Weinberg Principle; 5.2 Hardy-Weinberg Proportions; 5.3 Testing for Hardy-Weinberg Proportions; 5.3.1 Small sample sizes or many alleles; 5.3.2 Multiple simultaneous tests; 5.4 Estimation of Allele Frequencies; 5.4.1 Recessive alleles; 5.4.2 Null alleles; 5.5 Sex-Linked Loci; 5.5.1 Pseudoautosomal inheritance; 5.6 Estimation of Genetic Variation; 5.6.1 Heterozygosity; 5.6.2 Allelic richness; 5.6.3 Proportion of polymorphic loci Guest Box 5: Paul Sunnucks and Birgita D. Hansen, Null alleles and Bonferroni 'abuse': treasure your exceptions (and so get it right for Leadbeater's possum) |
| Record Nr. | UNINA-9910811227903321 |
|
Allendorf Frederick William
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||
| Chichester, West Sussex, : John Wiley & Sons, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Dawkins God : genes, memes, watchmakers, and delusions / / Alister E. McGrath
| Dawkins God : genes, memes, watchmakers, and delusions / / Alister E. McGrath |
| Autore | McGrath Alister E. <1953-> |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Chichester, England : , : Wiley Blackwell, , 2015 |
| Descrizione fisica | 1 online resource (205 p.) |
| Disciplina | 261.5/5 |
| Collana | New York Academy of Sciences |
| Soggetto topico | Apologetics |
| ISBN |
1-118-96479-9
1-118-96399-7 |
| Classificazione |
161
467 261.55 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Darwinism : the rise of a scientific theory -- The selfish gene : a Darwinian view of the world -- Blind faith? : evidence, proof, and rationality in science and religion -- The blind watchmaker : evolution and the elimination of God? -- Cultural darwinism? : the invention of the meme -- The God delusion : Dawkins on atheism, science, and religion. |
| Record Nr. | UNINA-9910787919103321 |
|
McGrath Alister E. <1953->
|
||
| Chichester, England : , : Wiley Blackwell, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Dawkins God : genes, memes, watchmakers, and delusions / / Alister E. McGrath
| Dawkins God : genes, memes, watchmakers, and delusions / / Alister E. McGrath |
| Autore | McGrath Alister E. <1953-> |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Chichester, England : , : Wiley Blackwell, , 2015 |
| Descrizione fisica | 1 online resource (205 p.) |
| Disciplina | 261.5/5 |
| Collana | New York Academy of Sciences |
| Soggetto topico | Apologetics |
| ISBN |
1-118-96479-9
1-118-96399-7 |
| Classificazione |
161
467 261.55 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Darwinism : the rise of a scientific theory -- The selfish gene : a Darwinian view of the world -- Blind faith? : evidence, proof, and rationality in science and religion -- The blind watchmaker : evolution and the elimination of God? -- Cultural darwinism? : the invention of the meme -- The God delusion : Dawkins on atheism, science, and religion. |
| Record Nr. | UNINA-9910807226203321 |
|
McGrath Alister E. <1953->
|
||
| Chichester, England : , : Wiley Blackwell, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Integrative organismal biology / / edited by Lynn B Martin, Cameron K Ghalambor, H. Arthur Woods
| Integrative organismal biology / / edited by Lynn B Martin, Cameron K Ghalambor, H. Arthur Woods |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2015] |
| Descrizione fisica | 1 online resource (360 pages) : illustrations (some color) |
| Disciplina | 576.5/4 |
| Soggetto topico |
Nature and nurture
Variation (Biology) |
| ISBN |
1-118-39881-5
1-118-39880-7 |
| Classificazione |
467
576.54 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910648493103321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Integrative organismal biology / / edited by Lynn B Martin, Cameron K Ghalambor, H. Arthur Woods
| Integrative organismal biology / / edited by Lynn B Martin, Cameron K Ghalambor, H. Arthur Woods |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2015] |
| Descrizione fisica | 1 online resource (360 pages) : illustrations (some color) |
| Disciplina | 576.5/4 |
| Soggetto topico |
Nature and nurture
Variation (Biology) |
| ISBN |
1-118-39881-5
1-118-39880-7 |
| Classificazione |
467
576.54 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910808962603321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular and quantitative animal genetics / / edited by Hasan Khatib
| Molecular and quantitative animal genetics / / edited by Hasan Khatib |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , c2015 |
| Descrizione fisica | 1 online resource (331 pages) : illustrations (some color) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property Animals Genetics Molecular Biology |
| ISBN |
1118677323
9781118677322 |
| Classificazione |
481.39
467 QH 432 591.3/5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Record Nr. | UNINA-9910796080803321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , c2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular and quantitative animal genetics / / edited by Hasan Khatib
| Molecular and quantitative animal genetics / / edited by Hasan Khatib |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , c2015 |
| Descrizione fisica | 1 online resource (331 pages) : illustrations (some color) |
| Disciplina | 591.3/5 |
| Soggetto topico |
Animal genetics
Intellectual property Animals Genetics Molecular Biology |
| ISBN |
1118677323
9781118677322 |
| Classificazione |
481.39
467 QH 432 591.3/5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Nota di contenuto |
Cover -- Title page -- Copyright page -- Contents -- Contributors -- Manuscript Reviewers -- Preface -- 1: Decoding and Encoding the "DNA" of Teaching and Learning in College Classrooms -- Introduction -- Teaching and learning: definitions -- Understanding learning -- Research in learning -- Transferable and life-long learning skills and aptitudes -- Understanding teaching -- Research in teaching -- Implications for classroom design in the twenty-first century -- Architecture of an effective classroom -- Instructional features for life-long learning -- Toward an active learning classroom -- Final thoughts -- References -- Review questions -- Section 1: Quantitative and Population Genetics -- 2: Mating Systems: Inbreeding and Inbreeding Depression -- Introduction -- Inbreeding -- Genetic defects -- Inbreeding depression -- Cause of inbreeding depression -- Quantifying inbreeding -- Inbreeding coefficient -- Inbreeding coefficient formula -- Calculating inbreeding coefficients -- Genomics and inbreeding -- Summary -- Further reading -- References -- Review questions -- 3: Genomic Selection, Inbreeding, and Crossbreeding in Dairy Cattle -- Introduction -- Genomic selection -- Genotyping tools -- Parentage verification and discovery -- Individual genes with large effects -- Genotype imputation -- Genome-enabled breeding value prediction -- Applications of genomics to selection of elite breeding stock -- Applications of genomics to improvement of replacement heifers on commercial farms -- Crossbreeding -- Breed characteristics and complementarity -- Heterosis and crossbreeding systems -- Experiments and field results -- Inbreeding and genetic defects -- Relationships, inbreeding, and effective population size -- Inherited defects -- Inbreeding depression for quantitative traits -- Managing inbreeding and genetic diversity -- Summary -- References.
Review questions -- 4: Basic Genetic Model for Quantitative Traits -- Introduction -- Quantitative traits -- Expected value and variance: the normal distribution -- Basic genetic model for quantitative traits -- Heritability and selection -- Predicting rate of genetic change from selection -- Further reading -- References -- 5: Heritability and Repeatability -- Introduction -- Heritability -- Estimation of heritability and variance components -- Prediction of breeding values and of response to selection -- Repeatability -- References -- 6: Applications of Statistics in Quantitative Traits -- Population and sample -- Parameter and statistics -- Descriptive statistics -- Types of variables -- Descriptive statistics categorical (qualitative) data -- Descriptive statistics for quantitative variables -- Comparing of arithmetic mean, median, and mode -- Measures of dispersion -- Graphically examining the distribution of the data -- Graphical presentation of categorical data -- Graphical presentation of quantitative data -- Normal distribution -- Area under the curve -- Standard normal distributions -- Exploring relationships between variables -- Covariance -- Correlation -- Regression -- Summary -- Population and sample -- Descriptive statistics -- Graphically examining the distribution of the data -- Normal distribution -- Exploring relationships between variables -- Appendix 6.1 -- Further reading -- References -- Review questions -- Section 2: Applications of Genetics and Genomics to Livestock and Companion Animal Species -- 7: Genetic Improvement of Beef Cattle -- Introduction -- Single trait selection -- National cattle evaluation -- Multiple trait selection -- Summary -- Further reading -- References -- 8: Genetic Improvement in Sheep through Selection -- Products from sheep -- Selection among breeds. Selection within a breed or population and the Key Equation -- Adjustment for environmental effects -- Phenotypic selection -- Estimated breeding values (EBV) -- Using multiple sources of information -- Genetic correlations -- Selection intensity -- Generation interval (L) -- Predicting progress from selection -- National genetic improvement programs -- Summary -- Further reading -- References -- Review questions -- 9: Genetic Improvement Programs for Dairy Cattle -- Introduction -- Data collection infrastructure -- Milk recording -- Pedigree information -- Type classification -- Health, fertility, calving ability, and longevity data -- Progeny testing and AI programs -- Estimation of breeding values -- Pre-adjustment for known environmental effects -- Contemporary groups -- Animal model genetic evaluations -- Four paths of selection -- Selection for increased productivity -- Milk yield -- Component percentages and cheese yield -- Maintenance costs and efficiency of milk production -- Net merit index (income portion) -- Selection for functional traits -- Calving performance -- Male and female fertility -- Udder health and mastitis -- Mobility -- Frame size and body condition -- Culling and longevity -- Net merit index (expense portion) -- Sire selection -- Selection index or independent culling levels? -- Reliability and management of risk -- Gender-enhanced semen -- Summary -- Further reading -- References -- Review questions -- 10: Genetic and Genomic Improvement of Pigs -- Introduction -- Domestication of swine and breed development -- Methods of selection and mating systems -- Traits of economic importance -- Development of molecular genetic approaches -- QTL, candidate genes, and genetic improvement -- Sequencing the pig genome -- Genomic selection -- Databases -- Cloning, transgenics, and breeding pigs as biological models. Future applications to genetic improvement -- Acknowledgments -- Further reading -- References -- Review questions -- 11: Equine Genetics -- Color -- Introduction -- Base colors -- Modifiers to base colors -- Other modifications -- White markings -- Paint/pinto patterns -- Genetic defects -- Introduction -- Dominant disorders -- Recessive disorders -- The genetics of health -- Inbreeding and relationship -- Inbreeding -- Relationship -- Selection and improvement -- Quantitative genetics -- Genetic improvement -- Genetic evaluation -- New technologies -- Cloning -- Equine genomics -- Further reading -- References -- Review questions -- 12: Genetics and Genomics of the Domestic Dog -- Introduction to canine research -- Domestication -- Breeding -- A model organism -- Genetic testing -- The dog genome -- Genomic tools -- Whole genome sequence -- Genome structure -- Uncovering the genetic basis of phenotypes -- Candidate gene approaches -- Genome-wide approaches -- Quantitative traits -- Future challenges -- Behavior -- Cancer -- Summary -- Further reading -- References -- Review questions -- 13: The Sheep Genome -- Investment in sheep genome research -- Overview of the sheep genome -- Genomic resources in sheep -- Physical map -- Linkage maps -- Radiation hybrid maps -- SNP arrays -- BAC library and end sequences -- Whole genome reference sequence -- Whole genome assembly -- Application of genomic resources -- Summary -- References -- Review questions -- 14: Goat Genetics and Genomic Progress -- Introduction -- Genetics and goat domestication -- Taxonomy -- Goat chromosome number and structure -- Patterns of inheritance -- Mendelian traits and exceptions -- Quantitative trail loci (QTL) -- Progress in goat genomics -- Biotechnologies and goat genetics -- Cloning -- Transgenic animals -- Summary -- Further reading -- Review questions. Section 3: Molecular Genetics of Production and Economically Important Traits -- 15: Bioinformatics in Animal Genetics -- Introduction -- Bioinformatics and animal genetics -- The importance of bioinformatics in genomics research -- Genome sequencing -- Alignment -- Genome assembly -- Annotation -- Gene expression -- Microarrays -- RNA-Seq -- Gene regulation -- Epigenetics -- Genomic data manipulation -- R language -- Bioconductor -- Web-based tools -- Bioinformatics perspectives in animal genetics -- References -- Review questions -- 16: Genome-wide Association Studies in Pedigreed Populations -- Introduction -- Experimental designs -- Genotyping and linkage disequilibrium -- Quality control -- The statistical analysis -- Significance testing -- Inspection of GWAS results -- Dealing with population structure -- Methods and tools for GWAS in pedigreed populations -- PLINK -- TASSEL -- EMMA/EMMAX -- GenABEL -- Things to remember about analysis -- What did we miss? -- Acknowledgments -- References -- 17: Molecular Genetics Techniques and High Throughput Technologies -- Central dogma of molecular biology -- Review of properties of nucleic acids -- Purification of nucleic acids from cells -- Determining the quantity and purity of nucleic acids -- UV spectrophotometry -- Fluorometry -- Gel electrophoresis -- Polymerase chain reaction (PCR) -- Determining the identity of DNA -- Chain termination method -- Restriction Fragment Length Polymorphism (RFLP) for variant genotyping -- Concept of parallelization and high throughput assays -- Microarray technology -- Array fabrication -- Labeling RNA -- Hybridization of cRNA -- Quantitation of hybridization -- Other applications of microarrays -- Next generation sequencing technology -- Introduction to next generation sequencing -- Unique challenges of next generation sequencing. Applications of next generation sequencing technologies. |
| Record Nr. | UNINA-9910813941103321 |
| Hoboken, New Jersey : , : Wiley Blackwell, , c2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Population genetics and microevolutionary theory / / Alan R. Templeton
| Population genetics and microevolutionary theory / / Alan R. Templeton |
| Autore | Templeton Alan Robert |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Liss, c2006 |
| Descrizione fisica | 1 online resource (717 p.) |
| Disciplina | 576.58 |
| Soggetto topico |
Population genetics
Evolution (Biology) |
| ISBN |
9780470047354
1-280-64901-1 9786610649013 0-470-04735-6 0-470-04721-6 |
| Classificazione |
467
576.5/8 |
| Formato | Multimedia  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | und |
| Nota di contenuto |
POPULATION GENETICS AND MICROEVOLUTIONARY THEORY; CONTENTS; PREFACE; 1. SCOPE AND BASIC PREMISES OF POPULATION GENETICS; PART I. POPULATION STRUCTURE AND HISTORY; 2. MODELING EVOLUTION AND THE HARDY-WEINBERG LAW; 3. SYSTEMS OF MATING; 4. GENETIC DRIFT; 5. GENETIC DRIFT IN LARGE POPULATIONS AND COALESCENCE; 6. GENE FLOW AND POPULATION SUBDIVISION; 7. GENE FLOW AND POPULATION HISTORY; PART II. GENOTYPE AND PHENOTYPE; 8. BASIC QUANTITATIVE GENETIC DEFINITIONS AND THEORY; 9. QUANTITATIVE GENETICS: UNMEASURED GENOTYPES; 10. QUANTITATIVE GENETICS: MEASURED GENOTYPES
PART III. NATURAL SELECTION AND ADAPTATION11. NATURAL SELECTION; 12. INTERACTIONS OF NATURAL SELECTION WITH OTHER EVOLUTIONARY FORCES; 13. UNITS AND TARGETS OF SELECTION; 14. SELECTION IN HETEROGENEOUS ENVIRONMENTS; 15. SELECTION IN AGE-STRUCTURED POPULATIONS; APPENDIX 1. GENETIC SURVEY TECHNIQUES; APPENDIX 2. PROBABILITY AND STATISTICS; REFERENCES; PROBLEMS AND ANSWERS; INDEX |
| Record Nr. | UNINA-9910143572403321 |
|
Templeton Alan Robert
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| Hoboken, N.J., : Wiley-Liss, c2006 | ||
| Multimedia | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
ゲノム創薬のためのバイオ統計：遺伝子情報解析の基礎と臨床応用(バイオ統計シリ－ズ) [[ゲノムキズグスリノタメノバイオトウケイイデンシジョウホウカイセキノキソトリンショウオウヨウバイオトウケイシリズ]]
| ゲノム創薬のためのバイオ統計：遺伝子情報解析の基礎と臨床応用(バイオ統計シリ－ズ) [[ゲノムキズグスリノタメノバイオトウケイイデンシジョウホウカイセキノキソトリンショウオウヨウバイオトウケイシリズ]] |
| Autore | 聡 舘田 英典 服部 |
| Pubbl/distr/stampa | 東京, : 近代科学社, 2010.6 |
| Descrizione fisica | オンライン資料1件 |
| Collana | バイオ統計シリーズ |
| Soggetto topico |
薬化学
遺伝子工学 遺伝学 バイオマーカー 生物測定学 |
| ISBN | 4-7649-7047-3 |
| Classificazione |
499.3
467 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | jpn |
| Nota di contenuto |
紙 -- バイオ統 シリーズ 刊 にあたって -- まえがき -- 目次 -- 第1章 メンデルの 伝法則 -- 1.1 メンデルの 伝実 -- 1.2 染 体と 伝子 -- 1.3 性染 体の 伝子と性決定 -- 1.4 メンデルの法則に従わない 伝現 -- 1.5 家系図を使った 伝様式の推定 -- 第2章 DNAの構 と -- 2.1 DNA デオキシリボ核 -- 2.2 DNAの -- 2.2.1 RNA リボ核 -- 2.3 伝子工学 -- 第3章 伝子の発現 -- 3.1 タンパクの構 -- 3.2 タンパクの合成における情報の流れ -- 3.3 写 -- 3.4 翻 -- 3.5 写の 細 -- 第4章 古典 伝学 -- 4.1 生活環と倍数性 -- 4.1.1 線 Caenorhabditis elegans -- 4.1.2 ゼニゴケ Marchatia -- 4.1.3 子植物トウモロコシ Zea mays -- 4.1.4 アカパンカビ Neurospora crassa -- 4.1.5 ゾウリムシ Parmecium -- 4.2 と組換え -- 4.2.1 -- 4.3 減数分 -- 4.4 組換え率の推定と 伝子地図 -- 4.5 組換えと 伝子変換 -- 4.6 ヒトにおける 伝子のマッピング -- 4.7 伝学のトピック -- 4.7.1 動く 伝子 -- 4.7.2 染 体の不活性化 -- 第5章 伝的変異 -- 5.1 突然変異 -- 5.1.1 点突然変異 -- 5.1.2 伝子 -- 5.1.3 染 体の変化 -- 5.2 生物 団内の 伝的変異 -- 第6章 伝子 度の変化 因 -- 6.1 次世代の 伝子型および 伝子 度 Hardy-Weinbergの法則 -- 6.1.1 Hardy-Weinberg比と 伝子 度 -- 6.1.2 Hardy-Weinberg比の検定 -- 6.1.3 多対立 伝子 -- 6.2 交 -- 6.2.1 交系数と 伝子型 度 -- 6.2.2 交係数の 算法 -- 6.2.3 交弱勢 -- 6.3 然淘汰 -- 6.3.1 然淘汰が有るときの 伝子 度変化の一 式 -- 6.3.2 定方向性淘汰 -- 6.3.3 平 淘汰 -- 6.4 突然変異 -- 6.4.1 突然変異の 化的効果 -- 6.4.2 突然変異と淘汰の平 -- 6.5 移住 -- 6.5.1 伝子 度への移住の効果 -- 6.5.2 移住と淘汰の平 -- 6.5.3 団の分化と固定指数 -- 6.6 伝的浮動 -- 6.6.1 有 団のWright-Fisherモデル -- 6.6.2 伝的浮動による 伝子 度の変化 -- 6.6.3 ヘテロ接合 度の減少 -- 6.6.4 団の 伝的分化 -- 6.6.5 団の有効な大きさ -- 6.6.6 伝的浮動と突然変異の平 -- 6.6.7 伝子の固定確率と 化 度 -- 6.6.8 伝子系図と 伝的浮動 -- 第7章 数 伝子座の取り扱い -- 7.1 2 伝子座の 団 伝学 -- 7.1.1 不平 -- 7.1.2 平 の検定 -- 7.1.3 不平 係数の時 変化 -- 7.1.4 不平 が生じる 因 -- 7.1.5 不平 を使った 伝病原因 伝子のマッピング -- 7.2 的 伝学 -- 7.2.1 的形 伝子座QTL -- 7.2.2 環境効果と広義の 伝率 -- 7.2.3 伝分散の分割と狭義の 伝率 -- 7.2.4 的形 への淘汰の効果 -- 7.2.5 QTLマッピング -- 7.2.6 候 伝子アプローチ -- 第8章 分子 化 -- 8.1 分子系統学 -- 8.1.1 法 -- 8.1.2 最大節約法 -- 8.1.3 最尤法 -- 8.1.4 分子系統樹推定の実例 -- 8.2 分子 化機構 分子 化の中立 -- 8.2.1 分子 化の中立 -- 8.2.2 中立 の予測と分子 化の様相 -- 8.2.3 応 化 伝子の探索 -- 第9章 バイオマーカー の と予後への影 の 価 -- 9.1 析の目的:乳癌におけるYB1の核内局在とEGFR familyとの および予後との -- 9.2 統 学的準備 -- 9.2.1 主成分分析.
9.2.2 グラフィカルモデリング -- 9.3 統 析の結果 -- 9.3.1 標準的な生存時 析と問 点 -- 9.3.2 主成分Cox回帰の 用 -- 9.3.3 グラフィカルモデリングの 用 -- 9.4 まとめと問 点 -- 第10章 剤感受性を 定するバイオマーカーの探索 -- 10.1 析の目的:明細 卵巣癌におけるタキサンの感受性を決定するバイオマーカーの同定 -- 10.2 統 学的準備 -- 10.2.1 回帰モデルによる偏りの 整 -- 10.2.2 傾向スコアによる偏りの 整 -- 10.3 統 析の結果 -- 10.3.1 Kaplan-Meier法による 析 -- 10.3.2 交互作用 析 -- 10.3.3 傾向スコアによる交互作用 析での偏りの 整 -- 10.4 まとめと問 点 -- 参 文献 -- 索引 -- 略歴 -- 奥付 -- お断り. |
| Record Nr. | UNINA-9910149236703321 |
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聡 舘田 英典 服部
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| 東京, : 近代科学社, 2010.6 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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