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Computational Biology [[electronic resource] ] : A Practical Introduction to BioData Processing and Analysis with Linux, MySQL, and R / / by Röbbe Wünschiers
| Computational Biology [[electronic resource] ] : A Practical Introduction to BioData Processing and Analysis with Linux, MySQL, and R / / by Röbbe Wünschiers |
| Autore | Wünschiers Röbbe |
| Edizione | [2nd ed. 2013.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (449 p.) |
| Disciplina | 570.285 |
| Soggetto topico |
Bioinformatics
Computational biology Bioinformatics Proteomics Biochemistry Application software Biophysics Biological physics R (Computer program language) Computer Appl. in Life Sciences Biochemistry, general Computer Applications Biological and Medical Physics, Biophysics |
| ISBN | 3-642-34749-5 |
| Classificazione | 42.10 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I Whetting Your Appetite -- 1 Introduction -- 2 Content of this Book -- Part II Computer & Operating Systems -- 3 Unix/Linux -- Part III Working with Linux -- 4 The First Touch -- 5 Working with Files -- 6 Remote Connections -- 7 Playing -- 8 Using the Shell -- 9 Installing BLAST+ and ClustalW -- 10 Shell Programming -- 11 Regular Expressions -- 12 Sed -- Part IV Programming -- 13 AWK -- 14 Perl -- 15 Other Programming Languages -- Part V Advanced Data Analysis -- 16 Relational Databases with MySQL -- 17 The Statistics Suite R -- Part VI Worked Examples -- 18 Genomic Analysis of the Pathogenicity Factors from E. coli Strain O157:H7 and EHEC Strain O104:H4 -- 19 Limits of BLAST & Homology Modeling -- 20 Virtual Sequencing of pUC18c -- 21 Querying for Potential Redox-Regulated Enzymes -- Part VII Additional Material -- References -- A Supplementary Information -- Solutions -- Index. |
| Record Nr. | UNINA-9910739430503321 |
Wünschiers Röbbe
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| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Systems biology [[electronic resource] ] : philosophical foundations / / edited by Fred C. Boogerd ... [et al.]
| Systems biology [[electronic resource] ] : philosophical foundations / / edited by Fred C. Boogerd ... [et al.] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, 2007 |
| Descrizione fisica | 1 online resource (361 p.) |
| Disciplina |
570.11
571 |
| Altri autori (Persone) | BoogerdFred C |
| Soggetto topico |
Biology - Philosophy
Biological systems Biological models |
| ISBN |
1-281-00380-8
9786611003807 0-08-047527-2 |
| Classificazione |
42.10
CC 3700 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Systems Biology; Copyright Page; Table of Contents; List of Contributors; Contributor Biographies; Preface; SECTION I Introduction; Chapter 1 Towards philosophical foundations of Systems Biology: introduction; 1. SYSTEMS BIOLOGY: A NEW SCIENCE IN SEARCH OF METHODOLOGIES AND PHILOSOPHICAL FOUNDATIONS; 2. SYSTEMS BIOLOGY; 2.1. History of systems biology; 2.2. What is contemporary systems biology?; 2.3. Approaches to systems biology; 3. TOWARDS A PHILOSOPHY OF SYSTEMS BIOLOGY; 3.1. The philosophy of molecular biology itself needs no further elaboration
3.2. Philosophers focus on philosophy of evolutionary biology3.3. A philosophy of systems biology is lacking but needed; 4. INTRODUCTION OF A NUMBER OF PHILOSOPHICAL ASPECTS OF SYSTEMS BIOLOGY; 4.1. Two types of reductionism; 4.2. A continuum of reductionism to antireductionism; 4.3. Types of explanation; 4.4. Mechanistic explanation; 4.5. Systems biology and models; 4.6. What is life?; 5. AIM AND OVERVIEW OF THE BOOK; REFERENCES; SECTION II Research programs of Systems Biology; Chapter 2 The methodologies of systems biology; SUMMARY 1. THE METHODOLOGY AND PHILOSOPHICAL FOUNDATIONS OF THE VARIOUS SCIENCES1.1. Physics; 1.2. Biology; 1.3. Biochemistry and molecular biology; 1.4. Cell Biology: The living cell; 2. LIMITATIONS TO THE SCIENTIFIC STATUS OF BIOCHEMISTRY AND MOLECULAR BIOLOGY; 2.1. Inaccuracy; 2.2. Inability to deal with emergence; 2.3. Frustrated aspiration of biochemistry and molecular biology to . . . biology; 2.4. Irreducibility; 2.5. Lack of testability because of undefinedness; 2.6. Lack of experimental accessibility; 2.7. Lack of analysability; 3. RISING ABOVE THE LIMITATIONS; 3.1. Genomics 3.2. Soon everything will be known . . . : Will biology become physics, at last?3.3. Observing or understanding?; 3.4. Systems biology; 4. TOWARDS A SYSTEMATIC METHODOLOGY OF SYSTEMS BIOLOGY; 4.1. The goals of systems biology; 4.2. Systems biology: What it is; 4.3. The spiral of knowledge; 4.4. The special role of mathematics in systems biology: Calculating emergence; ACKNOWLEDGEMENTS; REFERENCES; Chapter 3 Methodology is Philosophy; SUMMARY; 1. INTRODUCTION; 2. FROM MOLECULES TO DIABETES VIA METABOLISM AND SYSTEMIC PHYSIOLOGY; 3. MRS AND MCA FORM A SUCCESSFUL METHODOLOGY FOR SYSTEMS BIOLOGY 4. CONCLUSIONREFERENCES; Chapter 4 How can we understand metabolism?; SUMMARY; 1. INTRODUCTION; 2. TRADITIONAL PRINCIPLES OF METABOLISM; 3. THE RISE OF SYSTEMS ANALYSIS OF METABOLISM; 4. SHOULD WE EXPECT METABOLISM TO BE UNDERSTANDABLE?; 5. IS SIMULATING CELL METABOLISM THE SAME AS UNDERSTANDING IT?; REFERENCES; Chapter 5 On building reliable pictures with unreliable data: An evolutionary and developmental coda for the new systems biology?; SUMMARY; 1. INTRODUCTION; 2. THE NEW SYSTEMS BIOLOGY AND EVO-DEVO; 3. THE PROBLEM OF DATA RELIABILITY IN THE ANALYSIS OF LARGE SYSTEMS 4. DATA ERRORS AND MOLAR SYSTEM PROPERTIES |
| Record Nr. | UNINA-9910784597203321 |
| Amsterdam ; ; Boston, : Elsevier, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Systems biology [[electronic resource] ] : philosophical foundations / / edited by Fred C. Boogerd ... [et al.]
| Systems biology [[electronic resource] ] : philosophical foundations / / edited by Fred C. Boogerd ... [et al.] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, 2007 |
| Descrizione fisica | 1 online resource (361 p.) |
| Disciplina |
570.11
571 |
| Altri autori (Persone) | BoogerdFred C |
| Soggetto topico |
Biology - Philosophy
Biological systems Biological models |
| ISBN |
1-281-00380-8
9786611003807 0-08-047527-2 |
| Classificazione |
42.10
CC 3700 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Systems Biology; Copyright Page; Table of Contents; List of Contributors; Contributor Biographies; Preface; SECTION I Introduction; Chapter 1 Towards philosophical foundations of Systems Biology: introduction; 1. SYSTEMS BIOLOGY: A NEW SCIENCE IN SEARCH OF METHODOLOGIES AND PHILOSOPHICAL FOUNDATIONS; 2. SYSTEMS BIOLOGY; 2.1. History of systems biology; 2.2. What is contemporary systems biology?; 2.3. Approaches to systems biology; 3. TOWARDS A PHILOSOPHY OF SYSTEMS BIOLOGY; 3.1. The philosophy of molecular biology itself needs no further elaboration
3.2. Philosophers focus on philosophy of evolutionary biology3.3. A philosophy of systems biology is lacking but needed; 4. INTRODUCTION OF A NUMBER OF PHILOSOPHICAL ASPECTS OF SYSTEMS BIOLOGY; 4.1. Two types of reductionism; 4.2. A continuum of reductionism to antireductionism; 4.3. Types of explanation; 4.4. Mechanistic explanation; 4.5. Systems biology and models; 4.6. What is life?; 5. AIM AND OVERVIEW OF THE BOOK; REFERENCES; SECTION II Research programs of Systems Biology; Chapter 2 The methodologies of systems biology; SUMMARY 1. THE METHODOLOGY AND PHILOSOPHICAL FOUNDATIONS OF THE VARIOUS SCIENCES1.1. Physics; 1.2. Biology; 1.3. Biochemistry and molecular biology; 1.4. Cell Biology: The living cell; 2. LIMITATIONS TO THE SCIENTIFIC STATUS OF BIOCHEMISTRY AND MOLECULAR BIOLOGY; 2.1. Inaccuracy; 2.2. Inability to deal with emergence; 2.3. Frustrated aspiration of biochemistry and molecular biology to . . . biology; 2.4. Irreducibility; 2.5. Lack of testability because of undefinedness; 2.6. Lack of experimental accessibility; 2.7. Lack of analysability; 3. RISING ABOVE THE LIMITATIONS; 3.1. Genomics 3.2. Soon everything will be known . . . : Will biology become physics, at last?3.3. Observing or understanding?; 3.4. Systems biology; 4. TOWARDS A SYSTEMATIC METHODOLOGY OF SYSTEMS BIOLOGY; 4.1. The goals of systems biology; 4.2. Systems biology: What it is; 4.3. The spiral of knowledge; 4.4. The special role of mathematics in systems biology: Calculating emergence; ACKNOWLEDGEMENTS; REFERENCES; Chapter 3 Methodology is Philosophy; SUMMARY; 1. INTRODUCTION; 2. FROM MOLECULES TO DIABETES VIA METABOLISM AND SYSTEMIC PHYSIOLOGY; 3. MRS AND MCA FORM A SUCCESSFUL METHODOLOGY FOR SYSTEMS BIOLOGY 4. CONCLUSIONREFERENCES; Chapter 4 How can we understand metabolism?; SUMMARY; 1. INTRODUCTION; 2. TRADITIONAL PRINCIPLES OF METABOLISM; 3. THE RISE OF SYSTEMS ANALYSIS OF METABOLISM; 4. SHOULD WE EXPECT METABOLISM TO BE UNDERSTANDABLE?; 5. IS SIMULATING CELL METABOLISM THE SAME AS UNDERSTANDING IT?; REFERENCES; Chapter 5 On building reliable pictures with unreliable data: An evolutionary and developmental coda for the new systems biology?; SUMMARY; 1. INTRODUCTION; 2. THE NEW SYSTEMS BIOLOGY AND EVO-DEVO; 3. THE PROBLEM OF DATA RELIABILITY IN THE ANALYSIS OF LARGE SYSTEMS 4. DATA ERRORS AND MOLAR SYSTEM PROPERTIES |
| Record Nr. | UNINA-9910822197403321 |
| Amsterdam ; ; Boston, : Elsevier, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||