Autore	Lee Byong H.
Pubbl/distr/stampa	Hoboken, New Jersey : , : Wiley-Blackwell, , [2021]
Descrizione fisica	1 online resource (924 pages)
Disciplina	660.28449
Soggetto topico	Fermentation Industrial microbiology
Soggetto genere / forma	Electronic books.
ISBN	1-119-04277-1 1-119-04278-X 1-119-04279-8
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Cover -- Title Page -- Copyright -- Contents -- Preface -- Overview on Market Size of Bioproducts and Fundamentals of Cell Technology -- Chapter Part I Microbial Cell Technology -- 1.1 Basic bacterial growth and mode of fermentation -- 1.2 Basic fungal growth -- 1.3 Classical strain improvements and tools -- 1.3.1 Natural selection and mutation -- 1.3.2 Recombination -- 1.4 Modern strain improvement and tools -- 1.4.1 Genome shuffling -- 1.4.2 Recombinant DNA technology -- Summary -- 1.4.3 RNA interference (RNAi) and CRISPR/Cas technology for genome editing -- Summary -- 1.4.4 Molecular thermodynamics and down‐stream processes on bioproducts -- Summary -- 1.4.5 Protein engineering -- Summary -- 1.4.6 Genomics, proteomics, metagenomics, and bioinformatics -- Summary -- 1.4.7 Systems/synthetic biology and metabolic engineering -- Summary -- 1.4.8 Quorum sensing and quenching -- Summary -- 1.5 Bioengineering and scale‐up process -- 1.5.1 Microbial and process engineering factors affecting performance and economics -- 1.5.2 Fermenter and bioreactor systems -- 1.5.3 Mass transfer concept -- 1.5.4 Heat transfer concept -- 1.5.5 Mass and heat transfer practice -- 1.5.6 Scale‐up and scale‐down of fermentations -- 1.5.7 Scale‐up challenges -- Summary -- 1.6 New bioprocesses of fermentation -- 1.6.1 Growth‐arrested bioprocesses -- 1.6.2 Integrated bioprocesses -- 1.6.3 Consolidated bioprocessing (CBP) -- Summary -- Bibliography -- Chapter Part II Applications of Microbial Fermentation to Food Products, Chemicals and Pharmaceuticals -- 2.1 Fermented dairy products -- 2.1.1 Basic knowledge of manufacture of dairy products -- 2.1.2 Genetic engineering of lactic acid bacteria -- Summary -- Bibliography -- 2.2 Fermented meat and fish products -- 2.2.1 Fermented meat products -- 2.2.2 Fermented fish products -- Summary -- Bibliography. 2.3 Fermented vegetable and cereal products -- 2.3.1 Fermented vegetable products -- 2.3.2 Fermented cereal products -- Summary -- Bibliography -- 2.4 Organic acids -- 2.4.1 Acetic acid -- 2.4.2 Citric acid -- 2.4.3 Lactic acid -- 2.4.4 Malic acid -- 2.4.5 Fumaric acid -- Summary -- Bibliography -- 2.5 Fermentation‐derived food and feed ingredients -- 2.5.1 Flavors and amino acids -- Summary -- 2.5.2 Sweeteners -- Summary -- Bibliography -- 2.5.3 Vitamins and pigments -- Summary -- Bibliography -- 2.5.4 Microbial polysaccharides and biopolymers -- Summary -- Bibliography -- 2.6 Bacteriocins and bacteriophages -- 2.6.1 Bacteriocins -- 2.6.2 Bacteriophage -- Summary -- Bibliography -- 2.7 Enzymes -- Summary -- Bibliography -- 2.8 Biomass (SCP) and mushrooms -- 2.8.1 Biomass (SCP) -- 2.8.2 Mushrooms -- Summary -- Bibliography -- 2.9 Functional foods and nutraceuticals -- 2.9.1 Probiotics and prebiotics -- 2.9.2 Microbiome -- Summary -- Bibliography -- 2.10 Alcoholic beverages -- 2.10.1 Beer -- 2.10.2 Wine -- Summary -- Bibliography -- 2.11 Other fermentation chemicals -- 2.11.1 Bioethanol -- Summary -- Bibliography -- 2.11.2 Biobutanol -- Summary -- 2.11.3 Biobutanediol -- Summary -- Bibliography -- 2.11.4 Biodiesel -- Summary -- Bibliography -- 2.11.5 Biomethane -- Summary -- Bibliography -- 2.11.6 Biohydrogen -- Summary -- Bibliography -- 2.12 Pharmaceuticals, growth promoters, and biopesticides -- 2.12.1 Antibiotics -- 2.12.2 Antibiotic (or antimicrobial) growth promoters (AGPs) -- Summary -- Bibliography -- 2.12.3 Antitumor drugs -- Summary -- Bibliography -- 2.12.4 Steroids -- 2.12.5 Statins -- Summary -- Bibliography -- 2.12.6 Biopesticides -- Summary -- Bibliography -- Chapter Part III Animal Cell Technology -- 3.1 Animal cell culture -- 3.1.1 Introduction -- 3.1.2 Techniques of RNAi and CRISPR -- 3.1.3 Animal cell lines. 3.1.4 Upstream and downstream bioprocessing -- 3.1.5 Strain development of animal cell cultures -- 3.1.6 Applications of animal cell cultures -- 3.2 Transgenic animal bioreactors -- 3.2.1 Introduction and techniques -- 3.2.2 Applications of transgenic animals -- Summary -- Bibliography -- Chapter Part IV Plant Cell Technology -- 4.1 Introduction -- 4.2 Plant tissue culture -- 4.3 Applications of plant tissue culture -- 4.3.1 Traditional plant breeding (non‐recombinant DNA techniques) -- 4.3.2 General media for plant tissue culture -- 4.3.3 Bioreactor types of plant cell cultures -- 4.3.4 Modern plant breeding or Biotech/GM crops (recombinant DNA techniques) -- Summary -- Bibliography -- Index -- EULA.
Record Nr.	UNINA-9910554823603321

Pubbl/distr/stampa	Ontario, Canada : , : Pergamon Press, , 1981
Descrizione fisica	1 online resource (811 p.)
Disciplina	660.28449
Collana	Advances in Biotechnology
Soggetto topico	Fermentation Industrial microbiology Biochemical engineering
ISBN	1-4831-4845-9
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Front Cover; Scientific and Engineering Principles; Copyright Page; Editorial Board; Table of Contents; PREFACE; GUEST EDITORIAL I. IBIOCHEMICAL ENGINEERING: WHERE HAS IT BEEN AND WHERE IS IT GOING?; ""TECHNOLOGY-PULL"" AND ""SCIENCE-PUSH""; CURRENT STATE OF BIOCHEMICAL ENGINEERING; SOME SUGGESTIONS AND PROPOSALS; REFERENCES; GUEST EDITORIAL II. GENETICS AND INDUSTRIAL MICROBIOLOGY: STILL FURTHER HORIZONS; Section I:Microbial Cultures: Screening,Improvement, Patents; Chapter 1 . STRAIN IMPROVEMENT PROGRAMS IN ANTIBIOTIC-PRODUCING MICROORGANISMS- PRESENT AND FUTURE STRATEGIES; ABSTRACT KEYWORDSINTRODUCTIO; RATIONAL SELECTION PROCEDURES; POTENTIALS FOR R-DNA TECHNOLOGY IN MICROBIAL SELECTION; REFERENCES; Chapter 2. NEW ORGANISMS OF ECONOMIC IMPORTANCE: THE CASE OF FRANKIA; ABSTRACT; KEYWORDS; INTRODUCTION; LEGUMES; ACTINOMYCETES; CONCLUSIONS; ACKNOWLEDGEMENT; REFERENCES; Chapter 3. MIXED CULTURES IN INDUSTRIAL PROCESSES D.E.F. Harrison; ABSTRACT; KEYWORDS; INTRODUCTION; ADVANTAGES OF MIXED CULTURES FOR SCP PRODUCTION; OTHER APPLICATIONS OF MIXED CULTURES; DISADVANTAGES OF MIXED CULTURES; FUTURE PROSPECTS; REFERENCES; Chapter 4. CULTURES AND PATENTS Roman Saliwanchik ABSTRAGTKEYWORDS; DISCUSSION; CONCLUSION; REFERENCES; Chapter 5. PRODUCTION OF PHARMACOLOGICALLY ACTIVE AGENTS FROM MICROBIAL ORIGIN; ABSTRACT; KEYWORDS; INTRODUCTION; I. PROTEASE INHIBITORS; II. GLYCOSIDASE INHIBITORS; III. INHIBITORS OF HYDROLYTIC ENZYMES LOCATED ON THE CELL SURFACE; REFERENCES; Chapter 6. SCREENING OF BASIDIOMYCETES FOR THE PRODUCTION; ABSTRACT; KEYWORDS; INTRODUCTION; RESULTS AND DISCUSSION; ACKNOWLEDGEMENT; REFERENCES; Chapter 7. SCREENING OF BACTERIAL ISOLATES FOR ANTIGONOCOCCAL ACTIVITIES; ABSTRACT; KEYWORDS; INTRODUCTION; SCREENING; CRUDE PREPARATIONS; CONCLUSION ACKNOWLEDGEMENTREFERENCES; Chapter 8. ISOLATION OF CARBOXYL PROTEINASES OF MICROBIAL ORIGIN ON PEPSTATIN-SEPHAROSE RESIN; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; REFERENCES; Chaptre 9. RAPID STRAIN SELECTION FOR CITRIC ACID PRODUCTION; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; ACKNOWLEDGEMENT; REFERENCES; Chapter 10. USE OF CERULENIN IN SELECTING IMPROVED MUTANTS OF A DAUNORUBICIN-PRODUCING STREPTOMYCETE; ABSTRACT; KEYWORDS; INTRODUCTION; RESULTS AND DISCUSSION; ACKNOWLEDGEMENTS; REFERENCES Chapter 11. IMPROVEMENT OF THE DAUNORUBICIN FERMENTATION REALIZED AT 10,000 LITER FERMENTOR SCALEABSTRACT; KEYWORDS; INTRODUCTION; METHOD OF ASSAY FOR DAUNORUBICIN; FERMENTATION; RECOVERY; CONCLUSION; ACKNOWLEDGMENT; REFERENCES; Chapter 12. STUDIES ON THE AVERMECTIN FERMENTATION; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS; DISCUSSION; REFERENCES; Chapter 13. THE INFLUENCE OF OXYGEN CONCENTRATION ON MICROBIAL INSECTICIDE PRODUCTION; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS, DISCUSSION AND CONCLUSIONS; NOMENCLATURE; REFERENCES Section II Recombinant DNA and Microbial Genetics
Record Nr.	UNINA-9910789451903321

Autore	Benz Gregory T.
Pubbl/distr/stampa	Hoboken, New Jersey : , : Wiley : , : AIChe, , [2021]
Descrizione fisica	1 online resource (451 pages)
Disciplina	660.28449
Soggetto topico	Bioreactors - Equipment and supplies
Soggetto genere / forma	Electronic books.
ISBN	1-5231-4316-9 1-119-65053-4 1-119-65054-2 1-119-65050-X
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Foreword -- Foreword for Greg Benz -- Chapter 1 Purpose of Agitator Design -- References -- Chapter 2 Major Steps in Successful Agitator Design -- Define Process Results -- Define Process Conditions -- Choose Tank Geometry -- Calculate Equivalent Power/Airflow Combinations for Equal Mass Transfer Rate -- Choose Minimum Combined Power -- Choose Shaft Speed -- Size Impeller System to Draw Required Gassed Power -- Decision Point: D/T and Gassing Factors OK? -- Mechanical Design -- Decision Point: Is the Mechanical Design Feasible? -- Repeat to Find Lowest Cost -- Repeat for Different Aspect Ratios -- Repeat for Different Process Conditions -- Finish -- Summary of Chapter -- List of Symbols -- References -- Chapter 3 Agitator Fundamentals -- Agitated Tank Terminology -- Prime Mover -- Reducer -- Shaft Seal -- Wetted Parts -- Tank Dimensions -- How Agitation Parameters Are Calculated -- Reynolds Number -- Power Number -- Pumping Number -- Dimensionless Blend Time -- Aeration Number -- Gassing Factor -- Nusselt Number -- Froude Number -- Prandtl Number -- Geometric Ratios -- Baffle Number -- Dimensionless Hydraulic Force -- Thrust Number -- Typical Dimensionless Number Curves -- A Primer on Rheology -- Newtonian Model -- Pseudoplastic or Shear Thinning, Model (Aka Power Law Fluid) -- Bingham Plastic -- Herschel-Bulkley -- Impeller Apparent Viscosity -- A Bit of Impeller Physics -- Summary of Chapter -- List of Symbols -- Greek letters -- References -- Chapter 4 Agitator Behavior under Gassed Conditions -- Flooding -- kla Method -- Power Draw Method -- Visual Flow Pattern Method -- Effect on Power Draw -- Holdup -- Example of Holdup Calculation -- Holdup "War Story" -- Variable Gas Flow Operation -- Mechanical Effects -- Summary of Chapter -- List of Symbols -- References. Chapter 5 Impeller Types Used in Fermenters -- Impeller Flow Patterns -- Axial Flow -- Radial Flow -- Mixed Flow -- Chaos Flow -- Examples of Axial Flow Impellers -- Low Solidity -- High Solidity -- Up-pumping vs. Down Pumping -- Examples of Radial Flow Impellers -- Straight Blade Impeller -- Disc, aka Rushton, Turbines -- Smith Turbines -- CD-6 Turbine by Chemineer -- aka Smith Turbine by Many Manufacturers -- Deeply Concave Turbines -- Deep Asymmetric Concave Turbine with Overhang (BT-6) -- Examples of Mixed Flow Impellers -- Examples of Chaos Impellers -- Shear Effects -- Specialty Impellers -- Summary of Chapter -- List of Symbols -- References -- Chapter 6 Impeller Systems -- Why Do We Need a System? -- Reaction Engineering -- Fermenter History -- Steps to Impeller System Design -- Choose Number of Impellers -- Choose Placement of Impellers -- Choose Type(s) of Impellers -- Choose Power Split or Distribution Among Impellers -- Choose D/T and/or Shaft Speed -- D/T Effects with Variable Gas Flowrates -- Conclusions on D/T Ratio -- Design to Minimize Shear Damage -- Sparger Design -- Ring Sparger -- Pre-dispersion -- Fine Bubble Diffuser -- Summary of Chapter -- List of Symbols -- References -- Chapter 7 Piloting for Mass Transfer -- Why Pilot for Mass Transfer -- Methods for Determining kla -- Sulfite Method -- Dynamic Method -- aka Dynamic Gassing/Degassing Method -- Steady-State Method -- aka Mass Balance Method -- Combined Dynamic and Steady-State Method -- Equipment Needed for Scalable Data -- Data Gathering Needs -- Experimental Protocol -- Summary of Chapter -- List of Symbols -- References -- Chapter 8 Power and Gas Flow Design and Optimization -- What This Chapter Is about -- Where We Are in Terms of Design -- Design with no Data -- Design with Limited Pilot Data -- Design with Full Data -- Choose Minimum Combined Power. State of Design Completion -- Additional Considerations -- Summary of Chapter -- List of Symbols -- References -- Chapter 9 Optimizing Operation for Minimum Energy Consumption per Batch -- Purpose of This Chapter -- Prerequisite -- Conceptual Overview -- Detailed Procedure -- Minimizing Total Energy Usage -- Practical Design -- Additional Considerations -- Summary of Chapter -- List of Symbols -- References -- Chapter 10 Heat Transfer Surfaces and Calculations -- Purpose of This Chapter -- Design Philosophy -- Overview of the Problem -- Heat Sources -- Cooling Sources -- Heat Exchange Surface Overview -- Principle of Heat Transfer Calculation -- Calculations By Type of Surface -- Vessel Jacket, Agitated Side -- Simple Unbaffled Jacket, Jacket Side -- Dimple Jacket, Jacket Side -- Half-Pipe Coil, Jacket Side -- Helical Coil, Inside -- Helical Coil, Process Side -- Vertical Tube Bundle, Inside -- Vertical Tube Bundle, Process Side -- Plate Coil, Inside -- Plate Coil, Process Side -- Example Problem: Vertical Tube Bundle -- Problem Statement -- Problem Solution -- Additional Consideration: Effect on Power Draw -- Additional Consideration: Forces on Heat Exchange Surfaces Used as Baffles -- Additional Consideration: Wall Viscosity -- Additional Consideration: Effect of Gas -- External Heat Exchange Loops -- Summary of Chapter -- List of Symbols -- References -- Further Readings -- Chapter 11 Gasses Other Than Air and Liquids Other Than Water -- General Principle -- Comments on Some Specific Gasses -- Ammonia -- Carbon Dioxide -- Carbon Monoxide -- Hydrogen -- Methane -- Oxygen -- Economic Factors -- Disposal Factors -- Effects of Different Gasses on kla -- Effects of Different Gasses on Driving Force -- Operating Condition Effects -- Constraints on Outlet Concentration -- Safety -- Liquids Other Than Water -- Summary of Chapter -- List of Symbols. References -- Chapter 12 Viscous Fermentation -- General Background -- Sources of Viscosity -- Viscosity Models for Broths -- Effect of Viscosity on Power Draw -- Example Problem -- Example Problem Answer -- Effect of Viscosity on kla -- Effect of Viscosity on Holdup -- Effect of Viscosity on Blend Time -- Effect of Viscosity on Flooding -- Caverns -- Estimating Cavern Size -- Xanthan and Gellan Gums -- Viscosity Models for Gums -- Installation Survey -- Effect of D/T and No. and Type of Impellers on Results in Xanthan Gum -- Production Curve -- Heat Transfer -- All-Axial Impeller Design -- Invisible Draft Tube vs. Axial/Radial Combination -- Mycelial Broths -- Typical Viscosity Model -- Morphology Effects -- Recommendations -- Summary of Chapter -- List of Symbols -- References -- Chapter 13 Three Phase Fermentation -- General Problem -- Effect on Mass Transfer -- Effect on Foam -- Emulsion vs. Suspension -- Complexity: How to Optimize Operation -- Summary of Chapter -- List of Symbols -- References -- Chapter 14 Use of CFD in Fermenter Design -- Purpose of This Chapter -- Basic Theory -- Methods of Presenting Data -- Velocity Distribution -- Cavern Formation -- Blending Progress -- Flow Around Coils -- Bubble Size, kla, Holdup -- DO Distribution -- Summary of Chapter -- List of Symbols -- References -- Chapter 15 Agitator Seal Design Considerations -- Introduction -- Terminology -- Main Functions of Fermenter Shaft Seals -- Common Types of Shaft Seals -- Material Considerations -- Methods of Lubricating Seals -- Seal Environmental Control and Seal Support System -- Seal Life Expectations -- Special Process Considerations -- Summary of Chapter -- Reference -- Chapter 16 Fermenter Agitator Mounting Methods -- Introduction -- Top Entering Methods -- Direct Nozzle Mount -- Beam Gear Drive Mount with Auxiliary Packing or Lip Seal. Beams Tied into Vessel Sidewall -- Beam Gear Drive Mount with Auxiliary Mechanical Seal -- Beams Tied into Vessel Sidewall -- Beam Gear Drive Mount with Auxiliary Mechanical Seal -- Beams Tied into Building Structure -- Complete Drive and Seal Mount to Beams Tied into Vessel Sidewall, with Bellows Connector -- Complete Drive and Seal Mount to Beams Tied into Building Structure, with Bellows Connector -- Bottom Entering Methods -- Direct Nozzle Mount -- Floor Gear Drive Mount with Auxiliary Packing or Lip Seal -- Floor Gear Drive Mount with Auxiliary Mechanical Seal -- Floor Integrated Drive and Seal Mount with Bellows Connector -- Summary of Chapter -- References -- Chapter 17 Mechanical Design of Fermenter Agitators -- Introduction -- Impeller Design Philosophy -- Discussion on Hydraulic Force -- Shaft Design Philosophy -- Shaft Design Based on Stress -- Simple Example Problem -- Sample Problem with Steady Bearing -- Shaft Design Based On Critical Speed -- Cantilevered Designs -- Example Problem -- Units with Steady Bearings -- Solid Shaft vs. Hollow Shaft -- Role of FEA in Overall Shaft Design-Simplified Discussion -- Agitator Gear Drive Selection Concepts -- Early History -- Loads Imposed -- Handle or Isolate Loads? -- Handle Loads Option 1: Oversized Commercial Gear Drive -- Handle Loads Option 2: Purpose-Built Agitator Drive -- Isolate Loads Option 1: Hollow Quill Integrated Drive with Flexibly Coupled Extension Shaft -- Isolate Loads Option 2: Outboard Support Bearing Module -- Bearing Life Considerations -- Noise Considerations -- Torsional Natural Frequency -- Important or Useful Mechanical Design Features -- Summary of Chapter -- List of Symbols -- Greek Letters -- References -- Chapter 18 Sanitary Design -- Introduction -- Definitions -- Construction Principles -- Wetted Parts Construction Methods -- Welded Construction -- In-Tank Couplings. Mounting Flange Area.
Record Nr.	UNINA-9910555076203321

Pubbl/distr/stampa	New York [etc.] : Academic Press
Descrizione fisica	v. ; 24 cm
Disciplina	660.28449
Soggetto topico	Fermentazione
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	: 1979. - XIV, 346 p.
Record Nr.	UNISA-990002734040203316

Edizione	[1st ed. 2017.]
Pubbl/distr/stampa	Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica	1 online resource (X, 303 p. 44 illus., 19 illus. in color.)
Disciplina	660.28449
Collana	Topics in Biodiversity and Conservation
Soggetto topico	Biodiversity Environmental law Environmental policy Sustainable development Biotechnology Environmental Law/Policy/Ecojustice Sustainable Development
ISBN	3-319-47935-0
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Forward -- 1. Bioprospecting: An Industrial Perspective -- 2. Current Status and Perspectives in Marine Biodiscovery -- 3. Contributions of microbial resource centers to bioprospecting of bacteria and filamentous microfungi -- 4. Bioprospecting Archaea: focus on extreme halophiles -- 5. Bioprospecting soil metagenomes for antibiotics -- 6. Biotechnological applications of the Roseobacter clade -- 7. Iwokrama fungal/plant bioprospecting project 2000-2003 - a model for the future?- 8. Bioprospecting with Brazilian fungi -- 9. Secondary metabolites of mine waste acidophilic fungi -- 10. Insect bioprospecting especially in India -- 11. Phages against infectious diseases -- 12. The role of biodiversity centres in bioprospecting: a case study from Sarawak -- 13. Legal and ethnoecological components of bioprospecting -- 14. Bioprospecting insights.
Record Nr.	UNINA-9910155294603321