Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Rodents [[electronic resource] /] / Committee on Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
| Rodents [[electronic resource] /] / Committee on Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1996 |
| Descrizione fisica | 1 online resource (179 p.) |
| Disciplina | 619/.93 |
| Collana | Laboratory animal management |
| Soggetto topico | Rodents as laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-19605-X
9786610196050 0-309-58577-5 0-585-01994-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910455898003321 |
| Washington, D.C., : National Academy Press, 1996 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Rodents / / Committee on Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
| Rodents / / Committee on Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C. : , : National Academy Press, , 1996 |
| Descrizione fisica | 1 online resource (179 pages) : illustrations |
| Disciplina | 619/.93 |
| Collana | Laboratory animal management |
| Soggetto topico | Rodents as laboratory animals |
| ISBN |
0-309-17692-1
1-280-19605-X 9786610196050 0-309-58577-5 0-585-01994-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778793303321 |
| Washington, D.C. : , : National Academy Press, , 1996 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Rodents / / Committee on Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
| Rodents / / Committee on Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1996 |
| Descrizione fisica | 1 online resource (179 pages) : illustrations |
| Disciplina | 619/.93 |
| Collana | Laboratory animal management |
| Soggetto topico | Rodents as laboratory animals |
| ISBN |
9786610196050
9780309176927 0309176921 9781280196058 128019605X 9780309585774 0309585775 9780585019949 0585019940 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Rodents -- Copyright -- Preface -- Contents -- 1 Laboratory Animals and Public Perspective -- REGULATORY ISSUES -- ETHICAL CONSIDERATIONS -- REFERENCES -- 2 Responsibilities of Animal Care and Use Committees -- PROGRAM OVERSIGHT -- PROTOCOL REVIEW -- PERSONNEL QUALIFICATIONS AND TRAINING -- OCCUPATIONAL HEALTH AND SAFETY -- USE OF HAZARDOUS AGENTS -- REFERENCES -- 3 Criteria for Selecting Experimental Animals -- SPECIES AND STOCKS -- Choosing a Species for Study -- Rodent Stocks -- Genetically Defined Stocks -- Nongenetically Defined Stocks -- STANDARDIZED NOMENCLATURE FOR RODENTS -- Inbred Strains -- Substrains -- Laboratory Codes -- F1 Hybrids -- Coisogenic, Congenic, and Segregating Inbred Strains -- Recombinant Inbred (RI) Strains -- Genes -- Loci That Are Members of a Series -- Alleles -- Transgenes -- Outbred Stocks -- QUALITY -- Microbiologic Quality -- Genetic Quality -- SELECTED ASPECTS OF EXPERIMENTAL DESIGN -- REFERENCES -- 4 Genetic Management of Breeding Colonies -- GENETICALLY DEFINED STOCKS -- Pedigrees -- Traceability -- Selection of Parental Pairs -- Genetic Uniformity -- Foundation or Nucleus Colonies, Expansion Colonies, and Production Colonies -- NONGENETICALLY DEFINED STOCKS -- CRYOPRESERVATION -- RECORD-KEEPING -- REFERENCES -- 5 Husbandry -- HOUSING -- Caging -- Housing Systems -- Space Recommendations -- ENVIRONMENT -- Microenvironment -- Temperature -- Humidity -- Ventilation -- Ventilation Rate -- Air Quality -- Relative Air Pressures -- Cage Ventilation -- Illumination -- Spectral Distribution -- Photoperiod -- Intensity -- Noise -- FOOD -- Types of Diets -- Criteria for Selecting Optimal Rations -- Quality Assurance -- Caloric Restriction -- WATER -- BEDDING -- SANITATION -- Cleaning -- Waste Containment and Disposal -- Pest Control -- IDENTIFICATION AND RECORDS -- RODENTS OTHER THAN RATS AND MICE -- Guinea Pigs.
Hamsters -- Gerbils -- Chinchillas -- REFERENCES -- 6 Veterinary Care -- PREVENTIVE MEDICINE -- Procurement -- Sources -- Transportation -- Quarantine and Stabilization -- Separation by Species, Source, and Health Status -- SURVEILLANCE, DIAGNOSIS, TREATMENT, AND CONTROL OF DISEASE -- Daily Observations of Animals -- Control of Infectious Diseases -- Sample Size for Monitoring -- Treatment and Control -- Necropsies -- EMERGENCY, WEEKEND, AND HOLIDAY CARE -- MINIMIZATION OF PAIN AND DISTRESS -- Recognition of Pain and Distress -- Alleviation of Pain -- Alleviation of Stress and Distress -- SURVIVAL SURGERY AND POSTSURGICAL CARE -- Anesthetics and Tranquilizers -- Preparation for Survival Surgery -- Sterilization of Instruments -- Monitoring During Surgery -- Postoperative Care -- EUTHANASIA -- REFERENCES -- 7 Facilities -- LOCATION AND DESIGN -- Centralization Versus Decentralization -- Functional Areas -- Space Requirements -- Relative Relationships of Space -- Corridors, Vestibules, and Anterooms -- Interstitial Space -- CONSTRUCTION AND ARCHITECTURAL FINISHES -- MONITORING -- SPECIAL REQUIREMENTS -- SECURITY -- REFERENCES -- 8 Rodents that Require Special Consideration -- IMMUNODEFICIENT RODENTS -- Husbandry -- Plastic Cages with Filter Tops -- Individually Ventilated Plastic Cages with Filter Tops -- Isolators -- HEPA-Filtered Airflow Systems -- Environmental Considerations -- Food and Bedding -- Water -- Health Monitoring -- WILD RODENTS -- Hazards -- Care and Breeding -- Peromyscus -- Woodchucks -- AGING COHORTS -- General Considerations -- Laboratory Mice -- Rats (Rattus norvegicus) -- Husbandry -- Record-Keeping -- Transportation and Stabilization -- Veterinary Care and Surveillance -- Other Rodent Species Used for Gerontological Research -- Other Species of Mus -- Peromyscus spp. -- Guinea Pigs -- Hamsters -- Gerbils. RODENT MODELS OF INSULIN-DEPENDENT DIABETES MELLITUS -- Diabetes-Prone and Diabetes-Resistant Rats -- Breeding Techniques and Genetic Records -- Husbandry and Care -- Use of Spleen Cells to Reduce Frequency of Diabetes and Improve Breeding Efficiency -- Shipping Pathogen-Free Rats -- NOD Mice -- TRANSGENIC MICE -- Colony Management -- Embryo Donors -- Embryo Recipients -- Offspring -- Breeding Transgenic Mice -- Identification, Records, and Genetic Monitoring -- Embryo Cryopreservation -- Data Management -- Shipment and Receipt of Transgenic Rodents -- Human Health Hazards -- Administrative Issues -- REFERENCES -- Appendix Sources of Information on Importing Rodents -- Index. |
| Record Nr. | UNINA-9910970044203321 |
| Washington, D.C., : National Academy Press, 1996 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||