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Fluid resuscitation [[electronic resource] ] : state of the science for treating combat casualties and civilian injuries / / Andrew Pope ... [et al.] ; Institute of Medicine
| Fluid resuscitation [[electronic resource] ] : state of the science for treating combat casualties and civilian injuries / / Andrew Pope ... [et al.] ; Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c1999 |
| Descrizione fisica | 1 online resource (207 p.) |
| Disciplina | 617.2/1 |
| Altri autori (Persone) | PopeAndrew MacPherson <1950-> |
| Soggetto topico |
Hemorrhagic shock - Treatment
Fluid therapy Resuscitation Medicine, Military First aid in illness and injury |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-18596-1
9786610185962 0-309-59701-3 0-585-08494-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910455932003321 |
| Washington, D.C., : National Academy Press, c1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fluid resuscitation : state of the science for treating combat casualties and civilian injuries / / Andrew Pope [et al.] ; Institute of Medicine
| Fluid resuscitation : state of the science for treating combat casualties and civilian injuries / / Andrew Pope [et al.] ; Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C. : , : National Academy Press, , 1999 |
| Descrizione fisica | 1 online resource (207 pages) : illustrations |
| Disciplina | 617.2/1 |
| Altri autori (Persone) | PopeAndrew MacPherson <1950-> |
| Soggetto topico |
Hemorrhagic shock - Treatment
Fluid therapy Resuscitation Medicine, Military First aid in illness and injury |
| ISBN |
0-309-17279-9
1-280-18596-1 9786610185962 0-309-59701-3 0-585-08494-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778652603321 |
| Washington, D.C. : , : National Academy Press, , 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fluid resuscitation : state of the science for treating combat casualties and civilian injuries / / Andrew Pope ... [et al.] ; Institute of Medicine
| Fluid resuscitation : state of the science for treating combat casualties and civilian injuries / / Andrew Pope ... [et al.] ; Institute of Medicine |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c1999 |
| Descrizione fisica | 1 online resource (207 pages) : illustrations |
| Disciplina | 617.2/1 |
| Altri autori (Persone) | PopeAndrew MacPherson <1950-> |
| Soggetto topico |
Hemorrhagic shock - Treatment
Fluid therapy Resuscitation Medicine, Military First aid in illness and injury |
| ISBN |
9786610185962
9780309172790 0309172799 9781280185960 1280185961 9780309597012 0309597013 9780585084947 0585084947 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Fluid Resuscitation -- Copyright -- Reviewers -- Preface -- Photographs -- Contents -- Executive Summary -- 1 Introduction -- HISTORY OF FLUID RESUSCITATION -- ORIGIN, SCOPE AND ORGANIZATION OF THE REPORT -- 2 Pathophysiology of Acute Hemorrhagic Shock -- DEFINITIONS OF HEMORRHAGIC SHOCK -- Organ Involvement in Shock -- PHYSIOLOGIC RESPONSES TO HEMORRHAGE -- Shock Decompensation -- Cellular Responses to Shock -- Altered Energy Metabolism, Ion Compartmentalization, Lipid Metabolism, and Radical Production and Metabolism -- Alterations in Macrophage Function -- Surgical Bleeding Disorders -- Fundamental Alterations in Transcription and Translation: Apoptosis -- Alterations in Secretion of and Cellular Responsiveness to Growth Factors -- HEMATOLOGIC ABNORMALITIES ASSOCIATED WITH SHOCK AND RESUSCITATION -- Transfusion of the Patient in Shock -- Massive Transfusion -- Risks of Blood Transfusion -- Blood Substitutes and Alternatives to Transfusion -- Disseminated Intravascular Coagulation -- CONCLUSIONS AND RECOMMENDATIONS -- 3 Experience With and Complications of Fluid Resuscitation -- OVERVIEW OF COLLOID AND CRYSTALLOID RESUSCITATION -- COMPLICATIONS OF RESUSCITATION IN GENERAL -- Effects of Fluid Resuscitation on Coagulation -- Oxygen Toxicity Associated with Resuscitation -- Reperfusion-Mediated Injury -- Oxygen-Derived Free Radicals -- Nitric Oxide -- Activated Neutrophils -- Complications of Late Resuscitation of Shock -- COMPLICATIONS OF COLLOID RESUSCITATION -- COMPLICATIONS OF CRYSTALLOID RESUSCITATION -- Effects of Crystalloid Resuscitation on Immune Function -- Effects of Crystalloid Resuscitation on Cytokine Response -- Adverse Effects of Large-Volume Crystalloid Resuscitation -- Adverse Effects of Lactated Ringer's Solution -- Safety and Efficacy of Hypertonic Saline Solutions -- ALTERNATIVE RESUSCITATION APPROACHES -- SUMMARY.
CONCLUSIONS AND RECOMMENDATIONS -- 4 Novel Approaches to Treatment of Shock -- PREVENTION -- Oxygen Therapeutics -- First-, Second-, and Third-Generation Therapeutics -- Perfluorochemicals -- Liposomes -- Other Novel Approaches -- INTERVENTION -- Targets for Intervention -- Therapies for Reperfusion-Mediated Free-Radical Damage -- Antioxidant or Scavenging Strategies -- Iron Chelation -- Inhibition of Polymorphonuclear Neutrophil Adherence and Activation -- Nitric Oxide Inhibition -- Novel Strategies for Scavenging Free Radicals -- Hormonal Influences -- Diagnostic Instrumentation -- TOLERANCE -- RECOMMENDATIONS -- 5 Protocols of Care at the Site of Injury -- THE COMBAT ENVIRONMENT -- Expected Condition of Combatant on the Battlefield -- Limits of Battlefield Care for the Injured Combatant -- Resuscitation Needs of the Injured Combatant on the Battlefield -- Immediate Versus Delayed Fluid Resuscitation -- Current Protocols -- CONCLUSIONS AND RECOMMENDATIONS -- Training First Responders -- Available Approaches for Treatment of Injury -- Hemorrhage -- Airway and Breathing -- Additional Considerations -- Prompt Aeromedical Evacuation -- Monitoring -- 6 Future Directions -- ANIMAL MODELS -- Effects of Extent of Hypotension and Rates of Hemorrhage on Immune Function in Mouse Models -- Swine Models of Combined Hemorrhage and Injury -- Value of Animal Models -- Technical Models -- Role of Anesthesia -- CLINICAL TRIALS -- Role of Clinical Trials in Development of Therapies -- Endpoints and Indications -- Evaluation of Resuscitation Protocols -- Unique Problems of Clinical Trials of Trauma -- Heterogeneity of Subject Population -- Informed Consent -- Applicability of Civilian Clinical Data to Military Needs -- Clinical Research and Clinical Trials in Trauma Centers -- CONCLUSIONS AND RECOMMENDATIONS -- References -- Appendixes -- A Acknowledgments. Conference Speakers -- Conference Attendees -- Other Contributors -- B Acronyms -- C Conference Agenda -- D Committee and Staff Biographies -- Committee Biographies -- Iom Project Staff -- Index. |
| Record Nr. | UNINA-9910961763603321 |
| Washington, D.C., : National Academy Press, c1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||