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2017 oncology nursing drug handbook / / Gail M. Wilkes, MS, APRN-BC, AOCN, oncology nursing consultant Kilauea, Hawaii, Margaret Barton-Burke PhD, RN, FAAN, director of Nursing Research Memorial Sloan Kettering Cancer Center New York, New York
2017 oncology nursing drug handbook / / Gail M. Wilkes, MS, APRN-BC, AOCN, oncology nursing consultant Kilauea, Hawaii, Margaret Barton-Burke PhD, RN, FAAN, director of Nursing Research Memorial Sloan Kettering Cancer Center New York, New York
Autore Wilkes Gail M.
Pubbl/distr/stampa Burlington, MA : , : Jones & Bartlett, , [2017]
Descrizione fisica 1 online resource (3,329 pages) : illustrations
Disciplina 616.994061
Soggetto topico Cancer - Chemotherapy
Antineoplastic agents
Cancer - Nursing
ISBN 1-284-11719-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910162769603321
Wilkes Gail M.  
Burlington, MA : , : Jones & Bartlett, , [2017]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances and Prospects of 3-d Metal-Based Anticancer Drug Candidates / / by Farukh Arjmand, Sartaj Tabassum, Huzaifa Yasir Khan
Advances and Prospects of 3-d Metal-Based Anticancer Drug Candidates / / by Farukh Arjmand, Sartaj Tabassum, Huzaifa Yasir Khan
Autore Arjmand Farukh
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (292 pages)
Disciplina 616.994061
Altri autori (Persone) TabassumSartaj
KhanHuzaifa Yasir
Soggetto topico Cancer - Treatment
Cancer
Metabolism
Biochemistry
Cancer Therapy
Cancer Metabolism
ISBN 981-9701-46-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Introduction -- 2. Classification of Metal-Based Anticancer Chemotherapeutic Agents -- 3. Interaction Studies of Metal-Based Anticancer Drug Entities with Potential Therapeutic Targets -- 4. Biophysical and Spectroscopic Techniques to Validate the Interaction with Therapeutic targets -- 5. DNA Condensation Processes mediated by Metal-based Drug Entities and Morphological Studies -- 6. Molecular Docking and Computational in silico Investigations of Metal-Based Drug Agents -- 7.Biochemical Mechanistic Pathway of Cell Death Induced by Metal-Based Chemotherapeutic Agents -- 8.Combination Drug Strategies for Targeting Specific Biochemical Pathways for Superior Therapeutic Potency -- 9. Advanced Drug Delivery Strategies for Metal-Based Anticancer Drugs -- 10. Endoplasmic Reticulum(ER) Targeted Metal-Based Anticancer Chemotherapeutic Agents -- 11.Progress and Future Projections in Metal-Based Polymeric Anticancer Compounds -- 12. Conclusions.
Record Nr. UNINA-9910855392603321
Arjmand Farukh  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme
Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, , [2013]
Descrizione fisica 1 online resource (495 p.)
Disciplina 616.99
616.994061
Altri autori (Persone) PrudhommeMichelle
Collana Advances in anticancer agents in medicinal chemistry
Soggetto topico Antineoplastic agents
Pharmaceutical chemistry
Soggetto genere / forma Electronic books.
ISBN 1-60805-496-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Index
Record Nr. UNINA-9910463096803321
Sharjah : , : Bentham Science Publishers, , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme
Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, , [2013]
Descrizione fisica 1 online resource (495 p.)
Disciplina 616.99
616.994061
Altri autori (Persone) PrudhommeMichelle
Collana Advances in anticancer agents in medicinal chemistry
Soggetto topico Antineoplastic agents
Pharmaceutical chemistry
ISBN 1-60805-496-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Index
Record Nr. UNINA-9910787562603321
Sharjah : , : Bentham Science Publishers, , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme
Advances in anticancer agents in medicinal chemistry . Volume 2 / / edited by Michelle Prudhomme
Pubbl/distr/stampa Sharjah : , : Bentham Science Publishers, , [2013]
Descrizione fisica 1 online resource (495 p.)
Disciplina 616.99
616.994061
Altri autori (Persone) PrudhommeMichelle
Collana Advances in anticancer agents in medicinal chemistry
Soggetto topico Antineoplastic agents
Pharmaceutical chemistry
ISBN 1-60805-496-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Index
Record Nr. UNINA-9910822339303321
Sharjah : , : Bentham Science Publishers, , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in cancer drug targets . Volume 3 / / Atta-ur-Rahman, editor ; contributors Alain J. P. Alix [and thirty seven others]
Advances in cancer drug targets . Volume 3 / / Atta-ur-Rahman, editor ; contributors Alain J. P. Alix [and thirty seven others]
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2016
Descrizione fisica 1 online resource (278 p.)
Disciplina 616.994061
Collana Advances in Cancer Drug Targets
Soggetto topico Cancer - Chemotherapy
Drug targeting
Drug delivery systems
Soggetto genere / forma Electronic books.
ISBN 1-68108-233-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; PREFACE ; List of Contributors ; Neutrophil Elastase as a Target in Lung Cancer: the State of the Art ; 1. INTRODUCTION: NEUTROPHIL ELASTASE/Α-1ANTITRYPSIN IMBALANCE AS A LINK BETWEEN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND LUNG CANCER; 2. MULTIFACETED FUNCTIONS OF NEUTROPHIL ELASTASE IN LUNG CANCER; 3. ENDEGNENOUS NEUTROPHIL ELASTASE INHIBITORS; 3.1. Proteinaceous Inhibitors; 3.2. Natural Compounds; 3.2.1. Glycosaminoglycans; 3.2.2. Phenolics; 3.2.3. Triterpenoids ; 3.2.4. Fatty Acids and Peptide Derivatives; 4. DESIGN OF DUAL NEUTROPHIL ELASTASE / MMP INHIBITORS
DESIGN OF DUAL HNE-MMP INHIBITORSCONCLUDING REMARKS; ADDITIONAL MATERIAL; 1. Molecular Modeling and Molecular Graphics; 2. Ligand and Receptor Preparation; 3. Docking Protocol; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Inhibition of Membrane Complement Inhibitor Expression (CD46, CD55, CD59) by siRNA Sensitizes Tumor Cells to Complement Attack ; INTRODUCTION; MATERIALS AND METHODS; Cell Culture; SiRNA Sequences; SiRNA Transfection; Flow Cytometry; Complement-mediated Cytotoxicity Assay (CDC); C3-binding Studies; Real-Time RT-PCR; Statistical Analysis
RESULTSDesign of siRNAs Specific for CD46, CD55 and CD59; SiRNA-mediated Downregulation of mCRP Expression; siRNA-mediated Augmentation of Tumor Cell Complement Lysis and Opsonization; Time-course of siRNA-induced mCRP Inhibition; Stable Downregulation of CD59 Using an Hairpin siRNA Expression Vector; DISCUSSION; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGEMENT; ABBREVIATIONS; REFERENCES; Points of Therapeutic Intervention along the Wnt Signaling Pathway in Hepatocellular Carcinoma ; INTRODUCTION; THE WNT SIGNALING PATHWAY; Overview of the Wnt Signaling; The Wnt/β-catenin Pathway
Aberrant Activation of the Wnt/β-catenin Pathway in HCCTARGETING THE WNT/Β-CATENIN PATHWAY IN HCC; Targeting the Upstream Components; Endogenous Inhibitors of the Ligand/Receptor Complex; Targeting Wnt Ligands and FZD Receptors ; Targeting the Dishevelled Protein; Cellular Trafficking and Targets; Targeting the β-catenin Destruction Complex; Targeting the β-catenin/TCF Transcriptional Complex; Pitfalls in Targeting the Wnt/β-catenin Pathway; CONCLUSIONS AND PERSPECTIVES ; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGMENT; ABBREVIATIONS; REFERENCES
Collaboration of Epithelial Mesenchymal Transition and Cancer Stem Cells: Sinister Routes for Chemoresistant Recurrent Ovarian Cancer INTRODUCTION; PATHOLOGY OF OVARIAN CANCER; TRANSITION FROM EPITHELIAL TO MESENCHYMAL PHENOTYPE AND THE PROGRESSION OF CANCER ; EVIDENCE OF EMT IN OVARIAN CANCER; STEM CELLS IN NORMAL OVARIES AND OVARIAN CANCER; SPHERE FORMATION AND THE CANCER STEM CELL PHENOTYPE OF THE OVARY; ASSOCIATION OF EMT AND CSCS: A MERGER FOR POTENTIAL CHEMORESISTANCE IN OVARIAN CANCER
Cisplatin Induced EMT Generates Ovarian Cancer Stem-Like Cells: A Study on the OVCA 433 Cell Line as an Experimental Model
Record Nr. UNINA-9910511486903321
Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in cancer drug targets . Volume 3 / / Atta-ur-Rahman, editor ; contributors Alain J. P. Alix [and thirty seven others]
Advances in cancer drug targets . Volume 3 / / Atta-ur-Rahman, editor ; contributors Alain J. P. Alix [and thirty seven others]
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2016
Descrizione fisica 1 online resource (278 p.)
Disciplina 616.994061
Collana Advances in Cancer Drug Targets
Soggetto topico Cancer - Chemotherapy
Drug targeting
Drug delivery systems
ISBN 1-68108-233-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; PREFACE ; List of Contributors ; Neutrophil Elastase as a Target in Lung Cancer: the State of the Art ; 1. INTRODUCTION: NEUTROPHIL ELASTASE/Α-1ANTITRYPSIN IMBALANCE AS A LINK BETWEEN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND LUNG CANCER; 2. MULTIFACETED FUNCTIONS OF NEUTROPHIL ELASTASE IN LUNG CANCER; 3. ENDEGNENOUS NEUTROPHIL ELASTASE INHIBITORS; 3.1. Proteinaceous Inhibitors; 3.2. Natural Compounds; 3.2.1. Glycosaminoglycans; 3.2.2. Phenolics; 3.2.3. Triterpenoids ; 3.2.4. Fatty Acids and Peptide Derivatives; 4. DESIGN OF DUAL NEUTROPHIL ELASTASE / MMP INHIBITORS
DESIGN OF DUAL HNE-MMP INHIBITORSCONCLUDING REMARKS; ADDITIONAL MATERIAL; 1. Molecular Modeling and Molecular Graphics; 2. Ligand and Receptor Preparation; 3. Docking Protocol; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Inhibition of Membrane Complement Inhibitor Expression (CD46, CD55, CD59) by siRNA Sensitizes Tumor Cells to Complement Attack ; INTRODUCTION; MATERIALS AND METHODS; Cell Culture; SiRNA Sequences; SiRNA Transfection; Flow Cytometry; Complement-mediated Cytotoxicity Assay (CDC); C3-binding Studies; Real-Time RT-PCR; Statistical Analysis
RESULTSDesign of siRNAs Specific for CD46, CD55 and CD59; SiRNA-mediated Downregulation of mCRP Expression; siRNA-mediated Augmentation of Tumor Cell Complement Lysis and Opsonization; Time-course of siRNA-induced mCRP Inhibition; Stable Downregulation of CD59 Using an Hairpin siRNA Expression Vector; DISCUSSION; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGEMENT; ABBREVIATIONS; REFERENCES; Points of Therapeutic Intervention along the Wnt Signaling Pathway in Hepatocellular Carcinoma ; INTRODUCTION; THE WNT SIGNALING PATHWAY; Overview of the Wnt Signaling; The Wnt/β-catenin Pathway
Aberrant Activation of the Wnt/β-catenin Pathway in HCCTARGETING THE WNT/Β-CATENIN PATHWAY IN HCC; Targeting the Upstream Components; Endogenous Inhibitors of the Ligand/Receptor Complex; Targeting Wnt Ligands and FZD Receptors ; Targeting the Dishevelled Protein; Cellular Trafficking and Targets; Targeting the β-catenin Destruction Complex; Targeting the β-catenin/TCF Transcriptional Complex; Pitfalls in Targeting the Wnt/β-catenin Pathway; CONCLUSIONS AND PERSPECTIVES ; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGMENT; ABBREVIATIONS; REFERENCES
Collaboration of Epithelial Mesenchymal Transition and Cancer Stem Cells: Sinister Routes for Chemoresistant Recurrent Ovarian Cancer INTRODUCTION; PATHOLOGY OF OVARIAN CANCER; TRANSITION FROM EPITHELIAL TO MESENCHYMAL PHENOTYPE AND THE PROGRESSION OF CANCER ; EVIDENCE OF EMT IN OVARIAN CANCER; STEM CELLS IN NORMAL OVARIES AND OVARIAN CANCER; SPHERE FORMATION AND THE CANCER STEM CELL PHENOTYPE OF THE OVARY; ASSOCIATION OF EMT AND CSCS: A MERGER FOR POTENTIAL CHEMORESISTANCE IN OVARIAN CANCER
Cisplatin Induced EMT Generates Ovarian Cancer Stem-Like Cells: A Study on the OVCA 433 Cell Line as an Experimental Model
Record Nr. UNINA-9910798274803321
Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in cancer drug targets . Volume 3 / / Atta-ur-Rahman, editor ; contributors Alain J. P. Alix [and thirty seven others]
Advances in cancer drug targets . Volume 3 / / Atta-ur-Rahman, editor ; contributors Alain J. P. Alix [and thirty seven others]
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2016
Descrizione fisica 1 online resource (278 p.)
Disciplina 616.994061
Collana Advances in Cancer Drug Targets
Soggetto topico Cancer - Chemotherapy
Drug targeting
Drug delivery systems
ISBN 1-68108-233-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; PREFACE ; List of Contributors ; Neutrophil Elastase as a Target in Lung Cancer: the State of the Art ; 1. INTRODUCTION: NEUTROPHIL ELASTASE/Α-1ANTITRYPSIN IMBALANCE AS A LINK BETWEEN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND LUNG CANCER; 2. MULTIFACETED FUNCTIONS OF NEUTROPHIL ELASTASE IN LUNG CANCER; 3. ENDEGNENOUS NEUTROPHIL ELASTASE INHIBITORS; 3.1. Proteinaceous Inhibitors; 3.2. Natural Compounds; 3.2.1. Glycosaminoglycans; 3.2.2. Phenolics; 3.2.3. Triterpenoids ; 3.2.4. Fatty Acids and Peptide Derivatives; 4. DESIGN OF DUAL NEUTROPHIL ELASTASE / MMP INHIBITORS
DESIGN OF DUAL HNE-MMP INHIBITORSCONCLUDING REMARKS; ADDITIONAL MATERIAL; 1. Molecular Modeling and Molecular Graphics; 2. Ligand and Receptor Preparation; 3. Docking Protocol; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGEMENTS; ABBREVIATIONS; REFERENCES; Inhibition of Membrane Complement Inhibitor Expression (CD46, CD55, CD59) by siRNA Sensitizes Tumor Cells to Complement Attack ; INTRODUCTION; MATERIALS AND METHODS; Cell Culture; SiRNA Sequences; SiRNA Transfection; Flow Cytometry; Complement-mediated Cytotoxicity Assay (CDC); C3-binding Studies; Real-Time RT-PCR; Statistical Analysis
RESULTSDesign of siRNAs Specific for CD46, CD55 and CD59; SiRNA-mediated Downregulation of mCRP Expression; siRNA-mediated Augmentation of Tumor Cell Complement Lysis and Opsonization; Time-course of siRNA-induced mCRP Inhibition; Stable Downregulation of CD59 Using an Hairpin siRNA Expression Vector; DISCUSSION; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGEMENT; ABBREVIATIONS; REFERENCES; Points of Therapeutic Intervention along the Wnt Signaling Pathway in Hepatocellular Carcinoma ; INTRODUCTION; THE WNT SIGNALING PATHWAY; Overview of the Wnt Signaling; The Wnt/β-catenin Pathway
Aberrant Activation of the Wnt/β-catenin Pathway in HCCTARGETING THE WNT/Β-CATENIN PATHWAY IN HCC; Targeting the Upstream Components; Endogenous Inhibitors of the Ligand/Receptor Complex; Targeting Wnt Ligands and FZD Receptors ; Targeting the Dishevelled Protein; Cellular Trafficking and Targets; Targeting the β-catenin Destruction Complex; Targeting the β-catenin/TCF Transcriptional Complex; Pitfalls in Targeting the Wnt/β-catenin Pathway; CONCLUSIONS AND PERSPECTIVES ; CONFLICT OF INTEREST; DISCLOSURE; ACKNOWLEDGMENT; ABBREVIATIONS; REFERENCES
Collaboration of Epithelial Mesenchymal Transition and Cancer Stem Cells: Sinister Routes for Chemoresistant Recurrent Ovarian Cancer INTRODUCTION; PATHOLOGY OF OVARIAN CANCER; TRANSITION FROM EPITHELIAL TO MESENCHYMAL PHENOTYPE AND THE PROGRESSION OF CANCER ; EVIDENCE OF EMT IN OVARIAN CANCER; STEM CELLS IN NORMAL OVARIES AND OVARIAN CANCER; SPHERE FORMATION AND THE CANCER STEM CELL PHENOTYPE OF THE OVARY; ASSOCIATION OF EMT AND CSCS: A MERGER FOR POTENTIAL CHEMORESISTANCE IN OVARIAN CANCER
Cisplatin Induced EMT Generates Ovarian Cancer Stem-Like Cells: A Study on the OVCA 433 Cell Line as an Experimental Model
Record Nr. UNINA-9910822427603321
Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Anti-angiogenesis drug discovery and development . Volume 4 / / edited by Atta-ur-Rahman & M. Iqbal Chaudhary
Anti-angiogenesis drug discovery and development . Volume 4 / / edited by Atta-ur-Rahman & M. Iqbal Chaudhary
Pubbl/distr/stampa Sharjah, U.A.E. : , : Bentham Books, , [2019]
Descrizione fisica 1 online resource (242 pages)
Disciplina 616.994061
Soggetto topico Neovascularization inhibitors
Soggetto genere / forma Electronic books.
ISBN 1-68108-397-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910511675703321
Sharjah, U.A.E. : , : Bentham Books, , [2019]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Anti-angiogenesis drug discovery and development . Volume 4 / / edited by Atta-ur-Rahman & M. Iqbal Chaudhary
Anti-angiogenesis drug discovery and development . Volume 4 / / edited by Atta-ur-Rahman & M. Iqbal Chaudhary
Pubbl/distr/stampa Sharjah, U.A.E. : , : Bentham Books, , [2019]
Descrizione fisica 1 online resource (242 pages)
Disciplina 616.994061
Soggetto topico Neovascularization inhibitors
ISBN 1-68108-397-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910796793403321
Sharjah, U.A.E. : , : Bentham Books, , [2019]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui