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Leukaemia Diagnosis
Leukaemia Diagnosis
Autore Bain Barbara J
Edizione [6th ed.]
Pubbl/distr/stampa Newark : , : John Wiley & Sons, Incorporated, , 2024
Descrizione fisica 1 online resource (653 pages)
Disciplina 616.99/419075
Altri autori (Persone) LeachMike
ISBN 1-394-21860-5
1-394-21861-3
1-394-21859-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgements -- Commonly Used Abbreviations -- Chapter 1 The Nature of Leukaemia, Cytology, Cytochemistry and the Morphological Classification of Acute Leukaemia -- The nature of leukaemia -- The aetiology of leukaemia -- The importance of classification -- The nature and classification of acute leukaemia -- The nature and classification of the myelodysplastic syndromes -- The nature and classification of chronic myeloid leukaemias and myelodysplastic/myeloproliferative neoplasms -- The nature and classification of lymphoid neoplasms -- Defining a blast cell, a promyelocyte and a promonocyte -- The FAB classification of acute leukaemia -- Diagnosing acute leukaemia -- Distinguishing between acute myeloid and acute lymphoblastic leukaemias -- Defining remission -- The incidence of acute leukaemia -- The FAB categories and other morphological categories of acute myeloid leukaemia -- Acute myeloid leukaemia with minimal evidence of myeloid differentiation: M0 acute myeloid leukaemia -- Acute myeloid leukaemia without maturation: M1 acute myeloid leukaemia -- Acute myeloid leukaemia with maturation: M2 acute myeloid leukaemia -- Acute hypergranular promyelocytic leukaemia: M3 acute myeloid leukaemia -- The variant form of acute promyelocytic leukaemia: M3 variant acute myeloid leukaemia -- Acute myelomonocytic leukaemia: M4 acute myeloid leukaemia -- Acute monocytic/monoblastic leukaemia: M5 acute myeloid leukaemia -- Acute myeloid leukaemia with predominant erythroid differentiation: M6 acute myeloid leukaemia -- Acute megakaryoblastic leukaemia: M7 acute myeloid leukaemia -- Acute eosinophilic leukaemia -- Acute basophilic leukaemia -- Acute mast cell leukaemia -- Langerhans cell leukaemia -- Hypoplastic or hypocellular acute myeloid leukaemia.
Clinical correlates of FAB categories of acute myeloid leukaemia -- The FAB classification of acute lymphoblastic leukaemia -- 'Acute lymphoblastic leukaemia' of L3 subtype -- Automated full blood counts in acute leukaemia -- References -- Chapter 2 Immunophenotyping and Cytogenetic/Molecular Genetic Analyis -- Introduction -- Immunophenotyping -- Problems and pitfalls in immunophenotyping -- Immunophenotype of normal haemopoietic cells -- Immunophenotyping in acute leukaemia -- Immunophenotyping in acute myeloid leukaemia -- Immunophenotyping in acute lymphoblastic leukaemia -- Immunophenotyping in mixed phenotype acute leukaemia -- Immunophenotyping in myelodysplastic syndromes, myeloproliferative neoplasms and overlap syndromes -- Immunophenotyping in myelodysplastic syndromes -- Immunophenotyping in myelodysplastic/myeloproliferative neoplasms -- Immunophenotyping in myeloproliferative neoplasms -- Immunophenotyping in suspected B-lineage lymphoproliferative disorders -- Immunophenotyping in suspected T-lineage lymphoproliferative disorders -- Immunophenotyping in suspected natural killer-lineage lymphoproliferative disorders -- Genetic analysis -- Cytogenetic analysis -- Problems and pitfalls in cytogenetic analysis -- FISH and comparative genomic hybridisation -- Problems and pitfalls in FISH analysis -- Molecular genetic analysis -- Problems and pitfalls in molecular genetic analysis -- The role of cytogenetic and molecular genetic analysis in haematological neoplasms -- Problems and pitfalls in cytogenetic and molecular genetic analysis -- Cytogenetic and molecular genetic analysis in acute leukaemia -- Measurable residual disease in acute leukaemia -- Cytogenetic and molecular genetic analysis in acute myeloid leukaemia -- Cytogenetic and molecular genetic analysis in acute lymphoblastic leukaemia -- Conclusions -- References.
Chapter 3 Acute Myeloid Leukaemia: Integration of Morphological, Immunophenotypic and Genetic Information: the WHO and International Consensus Classifications -- Introduction -- The WHO classification of acute myeloid leukaemia -- Acute myeloid leukaemia with defining genetic abnormalities -- Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion -- Acute myeloid leukaemia with other RUNX1 rearrangement -- Acute promyelocytic leukaemia with PML::RARA fusion -- Acute myeloid leukaemia with t(11 -- 17)(q23.2 -- q21.2) -- ZBTB16::RARA or other RARA rearrangements -- Acute myeloid leukaemia with CBFB::MYH11 fusion -- Acute myeloid leukaemia with KMT2A rearrangement, particularly KMT2A::MLLT3 associated with t(9 -- 11) (p21.3 -- q23.3) -- Acute myeloid leukaemia with other KMT2A rearrangement -- Acute myeloid leukaemia with DEK::NUP214 fusion -- Acute myeloid leukaemia with MECOM rearrangement -- Acute myeloid leukaemia with other 3q21 or 3q26 rearrangements -- Acute myeloid leukaemia with RBM15::MRTFA fusion -- Acute myeloid leukaemia with BCR::ABL1 fusion -- Acute myeloid leukaemia with NPM1 mutation -- Acute myeloid leukaemia with CEBPA mutation -- Acute myeloid leukaemia with NUP98 rearrangement -- Acute myeloid leukaemia with RUNX1 mutation -- Acute myeloid leukaemia, myelodysplasia-related -- Acute myeloid leukaemia with other defined genetic alterations -- Acute myeloid leukaemia with KAT6A::CREBBP -- Acute myeloid leukaemia with FUS::ERG -- Acute myeloid leukaemia, defined by differentiation -- Acute myeloid leukaemia with minimal differentiation -- Acute myeloid leukaemia without maturation -- Acute myeloid leukaemia with maturation -- Acute basophilic leukaemia -- Acute myelomonocytic leukaemia -- Acute monocytic leukaemia -- Acute erythroid leukaemia -- Acute megakaryoblastic leukaemia -- Myeloid sarcoma.
Acute myeloid leukaemia associated with antecedent and predisposing conditions -- Therapy-related acute myeloid leukaemia/acute myeloid leukaemia post cytotoxic therapy -- Acute myeloid leukaemia with germline predisposition -- Myeloid proliferation related to Down syndrome -- Transient abnormal myelopoiesis -- Acute myeloid leukaemia associated with Down syndrome -- The International Consensus Classification of acute myeloid leukaemia -- Other acute myeloid leukaemias and related conditions -- Acute myeloid leukaemia arising in a germ cell tumour with i(12p) -- Mast cell leukaemia -- Blastic plasmacytoid dendritic cell neoplasm -- Prognostic significance of cytogenetic and genetic abnormalities in acute myeloid leukaemia -- The role of immunophenotyping -- The diagnostic pathway -- Conclusions -- References -- Chapter 4 Acute Lymphoblastic Leukaemia and Acute Leukaemia of Mixed or Ambiguous Lineage -- Introduction -- The WHO classification of acute lymphoblastic leukaemia/lymphoblastic lymphoma of B lineage -- B lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities -- B lymphoblastic leukaemia/lymphoma with high hyperdiploidy -- B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion -- B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features -- B lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion -- B lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features -- B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement -- B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion -- B lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion -- B lymphoblastic leukaemia/lymphoma with t(5 -- 14)(q31.1 -- q32.1) -- IGH::IL3 -- B lymphoblastic leukaemia/lymphoma with hypodiploidy -- B lymphoblastic leukaemia/lymphoma with iAMP21 -- B lymphoblastic leukaemia/lymphoma with other defined genetic alterations.
B lymphoblastic leukaemia/lymphoma, not otherwise specified -- B lymphoblastic leukaemia/lymphoma in Down syndrome -- The International Consensus Classification of acute lymphoblastic leukaemia/lymphoblastic lymphoma of B lineage -- The WHO classification of acute lymphoblastic leukaemia/lymphoblastic lymphoma of T lineage -- T lymphoblastic leukaemia/lymphoma, not otherwise specified -- T lymphoblastic leukaemia/lymphoma with t(10 -- 14)(q24 -- q11.2) -- TLX1 dysregulation -- T lymphoblastic leukaemia/lymphoma with t(5 -- 14)(q35.1 -- q32.2) (cryptic) -- TLX3 dysregulation -- T lymphoblastic leukaemia/lymphoma with cryptic TALd deletion -- STIL::TAL1 -- T lymphoblastic leukaemia/lymphoma with NUP214::ABL1 fusion -- Early T-cell precursor lymphoblastic leukaemia/lymphoma -- The International Consensus Classification of acute lymphoblastic leukaemia/lymphoblastic lymphoma of T lineage -- Natural killer cell lymphoblastic leukaemia/lymphoma -- Therapy-related lymphoblastic leukaemia/lymphoma -- Acute leukaemias of mixed or ambiguous lineage -- Mixed phenotype acute leukaemias -- Mixed phenotype acute leukaemia with defined genetic abnormalities -- Mixed phenotype/ambiguous lineage acute leukaemia, defined by differentiation -- Mixed phenotype acute leukaemia, B/myeloid, not otherwise specified -- Mixed phenotype acute leukaemia, T/myeloid, not otherwise specified -- Mixed phenotype acute leukaemia, rare types -- Acute leukaemia of ambiguous lineage, not otherwise specified -- Acute undifferentiated leukaemia -- Conclusions -- References -- Chapter 5 The Myelodysplastic Syndromes, the Myelodysplastic/Myeloproliferative Neoplasms and Juvenile Myelomonocytic Leukaemia -- MYELODYSPLASTIC SYNDROMES/NEOPLASMS -- Recognition, nature and epidemiology -- Classification -- Cytochemistry -- Immunophenotyping -- Bone marrow trephine biopsy -- Cytogenetic features.
Molecular genetic features.
Record Nr. UNINA-9910830203403321
Bain Barbara J  
Newark : , : John Wiley & Sons, Incorporated, , 2024
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Leukaemia diagnosis / / Barbara J. Bain
Leukaemia diagnosis / / Barbara J. Bain
Autore Bain Barbara J
Edizione [4th ed.]
Pubbl/distr/stampa Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010
Descrizione fisica 1 online resource (403 p.)
Disciplina 616.99/419075
Soggetto topico Leukemia - Diagnosis
Medicine
ISBN 1-282-48239-4
9786612482397
1-4443-1847-0
1-4443-1848-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto LEUKAEMIA DIAGNOSIS; CONTENTS; PREFACE; ABBREVIATIONS; 1 THE NATURE OF LEUKAEMIA, CYTOLOGY, CYTOCHEMISTRY AND THE FAB CLASSIFICATION OF ACUTE LEUKAEMIA; 2 IMMUNOPHENOTYPING AND CYTOGENETIC/MOLECULAR GENETIC ANALYSIS IN LEUKAEMIA AND RELATED CONDITIONS; 3 ACUTE LEUKAEMIA: INTEGRATION OF MORPHOLOGICAL, IMMUNOPHENOTYPIC AND GENETIC INFORMATION AND THE WHO CLASSIFICATION; 4 THE MYELODYSPLASTIC SYNDROMES; 5 CHRONIC MYELOID LEUKAEMIAS; 6 LYMPHOID LEUKAEMIAS OF MATURE T, B AND NATURAL KILLER CELLS; APPENDIX: LEUKAEMIA DIAGNOSIS IN RESOURCE-POOR COUNTRIES; INDEX
Record Nr. UNINA-9910139361503321
Bain Barbara J  
Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui