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Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
Pubbl/distr/stampa New Jersey, : World Scientific, c2010
Descrizione fisica 1 online resource (352 p.)
Disciplina 616.9101
616.99/4019
616.994019
Altri autori (Persone) OuJ.-H. James <1954-> (Jing-hsiung James)
YenT. S. Benedict <1953-2009.> (Tien-Sze Benedict)
Soggetto topico Oncogenic viruses
Hepatitis viruses
Herpesviruses
Soggetto genere / forma Electronic books.
ISBN 1-282-76042-4
9786612760426
981-283-347-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Foreword; Preface; Chapter 1 Oncogenic Viruses, Cellular Transformation and Human Cancers Yanyan Zheng and Jing-hsiung James Ou; 1. Introduction and Historical Aspects; 2. Human Oncogenic Viruses; 2.1. Hepatitis B Virus (HBV); 2.2. Hepatitis C Virus (HCV); 2.3. Human Papilloma Virus (HPV); 2.4. Epstein-Barr Virus (EBV); 2.5. Kaposi's Sarcoma-associated Herpesvirus (KSHV); 2.6. Human T-cell Leukemia Virus-1 (HTLV-1); 3. Mechanisms of Virus-induced Cellular Transformation; 3.1. Perturbation of Signaling Pathways; 3.1.1. Mimicking the signaling ligands
3.1.2. Mimicking the cellular signaling receptors3.1.3. Mimicking the intracellular signaling adaptors; 3.1.4. Activation of cell surface receptors; 3.2. Deregulation of the Cell Cycle; 3.2.1. Abrogation of the RB function; 3.2.2. Enhancement of CDK activities; 3.2.3. Targeting of cyclin; 3.3. Escape of Apoptosis; 3.3.1. Inactivation of the "gatekeeper" p53; 3.3.2. Expression of viral version of Bcl-2 (vBcl-2); 3.4. Immortalization of Cells; 3.5. Induction of Genetic Instability; 3.6. Insertional Mutagenesis; 3.7. Induction of Chronic Inflammation; 4. Concluding Remarks; Bibliography
Chapter 2 Hepatitis B Virus and Hepatocellular Carcinogenesis T. S. Benedict Yen1. Hepatitis B Virus and Hepatocellular Carcinoma; 2. Biology and Epidemiology of HBV; 3. HBV Virology; 4. Prevention and Treatment of HBV; 5. Mechanisms of HBV Carcinogenesis; 5.1. Overview; 5.2. HBV-specific Factors; 5.2.1. X protein; 5.2.1.1. Function of X protein in the HBV life cycle; 5.2.1.2. Effect of X protein on transcription; 5.2.1.3. Effect of X protein on viral replication; 5.2.1.4. X protein and DDB1; 5.2.1.5. X-protein carcinogenesis; 5.2.2. Other viral proteins potentially involved in carcinogenesis
5.2.2.1. Truncated MSP5.2.2.2. preS2 mutants; 5.2.2.3. Core gene mutants; 5.2.3. Insertional mutagenesis; 5.3. Role of Liver Injury and Inflammation; 5.4. Dietary Carcinogens; 5.5. Other Aspects of HBV Oncogenesis; 5.5.1. Role of genotypes; 5.5.2. Role of sex hormones; 6. Summary; Note; References; Chapter 3 Molecular Mechanism of Hepatitis C Virus Carcinogenesis Keigo Machida, Jing-hsiung James Ou and Michael M. C. Lai; 1. Introduction; 2. Molecular Carcinogenesis of HCV; 2.1. Induction of Mutator Phenotype; 2.2. Chromosome Translocation; 2.3. Reactive Oxygen Species (ROS); 2.4. Nitric Oxide
2.5. Inhibition of DNA Damage Repair2.6. Oncogenic Activities of the HCV Core Protein; 2.6.1. TNF-α; 2.6.2. MAPK and AP-1; 2.6.3. NF-κB; 2.6.4. Oxidative stress; 2.6.5. Insulin resistance; 2.6.6. PPARα; 2.6.7. Proteasome activator PA28γ; 2.6.8. SOCS-1; 2.6.9. p53; 2.7. Oncogenic Activities of the HCV NS5A Protein; 3. Other Causative Factors in HCV-associated HCC; 3.1. Chronic Liver Inflammation; 3.2. Alcohol; 4. Endoplasmic Reticulum Stress and HCV Pathogenesis; 5. Gene Expression Profile of HCC; 6. HCV and Lymphomagenesis; 6.1. Induction of IgHypermutation by HCV
6.2. Induction of DNA Translocation between IgGenes and Proto-Oncogenes by HCV
Record Nr. UNINA-9910456103403321
New Jersey, : World Scientific, c2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
Pubbl/distr/stampa New Jersey, : World Scientific, c2010
Descrizione fisica 1 online resource (352 p.)
Disciplina 616.9101
616.99/4019
616.994019
Altri autori (Persone) OuJ.-H. James <1954-> (Jing-hsiung James)
YenT. S. Benedict <1953-2009.> (Tien-Sze Benedict)
Soggetto topico Oncogenic viruses
Hepatitis viruses
Herpesviruses
ISBN 1-282-76042-4
9786612760426
981-283-347-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Foreword; Preface; Chapter 1 Oncogenic Viruses, Cellular Transformation and Human Cancers Yanyan Zheng and Jing-hsiung James Ou; 1. Introduction and Historical Aspects; 2. Human Oncogenic Viruses; 2.1. Hepatitis B Virus (HBV); 2.2. Hepatitis C Virus (HCV); 2.3. Human Papilloma Virus (HPV); 2.4. Epstein-Barr Virus (EBV); 2.5. Kaposi's Sarcoma-associated Herpesvirus (KSHV); 2.6. Human T-cell Leukemia Virus-1 (HTLV-1); 3. Mechanisms of Virus-induced Cellular Transformation; 3.1. Perturbation of Signaling Pathways; 3.1.1. Mimicking the signaling ligands
3.1.2. Mimicking the cellular signaling receptors3.1.3. Mimicking the intracellular signaling adaptors; 3.1.4. Activation of cell surface receptors; 3.2. Deregulation of the Cell Cycle; 3.2.1. Abrogation of the RB function; 3.2.2. Enhancement of CDK activities; 3.2.3. Targeting of cyclin; 3.3. Escape of Apoptosis; 3.3.1. Inactivation of the "gatekeeper" p53; 3.3.2. Expression of viral version of Bcl-2 (vBcl-2); 3.4. Immortalization of Cells; 3.5. Induction of Genetic Instability; 3.6. Insertional Mutagenesis; 3.7. Induction of Chronic Inflammation; 4. Concluding Remarks; Bibliography
Chapter 2 Hepatitis B Virus and Hepatocellular Carcinogenesis T. S. Benedict Yen1. Hepatitis B Virus and Hepatocellular Carcinoma; 2. Biology and Epidemiology of HBV; 3. HBV Virology; 4. Prevention and Treatment of HBV; 5. Mechanisms of HBV Carcinogenesis; 5.1. Overview; 5.2. HBV-specific Factors; 5.2.1. X protein; 5.2.1.1. Function of X protein in the HBV life cycle; 5.2.1.2. Effect of X protein on transcription; 5.2.1.3. Effect of X protein on viral replication; 5.2.1.4. X protein and DDB1; 5.2.1.5. X-protein carcinogenesis; 5.2.2. Other viral proteins potentially involved in carcinogenesis
5.2.2.1. Truncated MSP5.2.2.2. preS2 mutants; 5.2.2.3. Core gene mutants; 5.2.3. Insertional mutagenesis; 5.3. Role of Liver Injury and Inflammation; 5.4. Dietary Carcinogens; 5.5. Other Aspects of HBV Oncogenesis; 5.5.1. Role of genotypes; 5.5.2. Role of sex hormones; 6. Summary; Note; References; Chapter 3 Molecular Mechanism of Hepatitis C Virus Carcinogenesis Keigo Machida, Jing-hsiung James Ou and Michael M. C. Lai; 1. Introduction; 2. Molecular Carcinogenesis of HCV; 2.1. Induction of Mutator Phenotype; 2.2. Chromosome Translocation; 2.3. Reactive Oxygen Species (ROS); 2.4. Nitric Oxide
2.5. Inhibition of DNA Damage Repair2.6. Oncogenic Activities of the HCV Core Protein; 2.6.1. TNF-α; 2.6.2. MAPK and AP-1; 2.6.3. NF-κB; 2.6.4. Oxidative stress; 2.6.5. Insulin resistance; 2.6.6. PPARα; 2.6.7. Proteasome activator PA28γ; 2.6.8. SOCS-1; 2.6.9. p53; 2.7. Oncogenic Activities of the HCV NS5A Protein; 3. Other Causative Factors in HCV-associated HCC; 3.1. Chronic Liver Inflammation; 3.2. Alcohol; 4. Endoplasmic Reticulum Stress and HCV Pathogenesis; 5. Gene Expression Profile of HCC; 6. HCV and Lymphomagenesis; 6.1. Induction of IgHypermutation by HCV
6.2. Induction of DNA Translocation between IgGenes and Proto-Oncogenes by HCV
Record Nr. UNINA-9910780891803321
New Jersey, : World Scientific, c2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Human oncogenic viruses / / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
Human oncogenic viruses / / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
Edizione [1st ed.]
Pubbl/distr/stampa New Jersey, : World Scientific, c2010
Descrizione fisica 1 online resource (352 p.)
Disciplina 616.9101
616.99/4019
616.994019
Altri autori (Persone) OuJ.-H. James <1954-> (Jing-hsiung James)
YenT. S. Benedict <1953-2009.> (Tien-Sze Benedict)
Soggetto topico Oncogenic viruses
Hepatitis viruses
Herpesviruses
ISBN 1-282-76042-4
9786612760426
981-283-347-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Foreword; Preface; Chapter 1 Oncogenic Viruses, Cellular Transformation and Human Cancers Yanyan Zheng and Jing-hsiung James Ou; 1. Introduction and Historical Aspects; 2. Human Oncogenic Viruses; 2.1. Hepatitis B Virus (HBV); 2.2. Hepatitis C Virus (HCV); 2.3. Human Papilloma Virus (HPV); 2.4. Epstein-Barr Virus (EBV); 2.5. Kaposi's Sarcoma-associated Herpesvirus (KSHV); 2.6. Human T-cell Leukemia Virus-1 (HTLV-1); 3. Mechanisms of Virus-induced Cellular Transformation; 3.1. Perturbation of Signaling Pathways; 3.1.1. Mimicking the signaling ligands
3.1.2. Mimicking the cellular signaling receptors3.1.3. Mimicking the intracellular signaling adaptors; 3.1.4. Activation of cell surface receptors; 3.2. Deregulation of the Cell Cycle; 3.2.1. Abrogation of the RB function; 3.2.2. Enhancement of CDK activities; 3.2.3. Targeting of cyclin; 3.3. Escape of Apoptosis; 3.3.1. Inactivation of the "gatekeeper" p53; 3.3.2. Expression of viral version of Bcl-2 (vBcl-2); 3.4. Immortalization of Cells; 3.5. Induction of Genetic Instability; 3.6. Insertional Mutagenesis; 3.7. Induction of Chronic Inflammation; 4. Concluding Remarks; Bibliography
Chapter 2 Hepatitis B Virus and Hepatocellular Carcinogenesis T. S. Benedict Yen1. Hepatitis B Virus and Hepatocellular Carcinoma; 2. Biology and Epidemiology of HBV; 3. HBV Virology; 4. Prevention and Treatment of HBV; 5. Mechanisms of HBV Carcinogenesis; 5.1. Overview; 5.2. HBV-specific Factors; 5.2.1. X protein; 5.2.1.1. Function of X protein in the HBV life cycle; 5.2.1.2. Effect of X protein on transcription; 5.2.1.3. Effect of X protein on viral replication; 5.2.1.4. X protein and DDB1; 5.2.1.5. X-protein carcinogenesis; 5.2.2. Other viral proteins potentially involved in carcinogenesis
5.2.2.1. Truncated MSP5.2.2.2. preS2 mutants; 5.2.2.3. Core gene mutants; 5.2.3. Insertional mutagenesis; 5.3. Role of Liver Injury and Inflammation; 5.4. Dietary Carcinogens; 5.5. Other Aspects of HBV Oncogenesis; 5.5.1. Role of genotypes; 5.5.2. Role of sex hormones; 6. Summary; Note; References; Chapter 3 Molecular Mechanism of Hepatitis C Virus Carcinogenesis Keigo Machida, Jing-hsiung James Ou and Michael M. C. Lai; 1. Introduction; 2. Molecular Carcinogenesis of HCV; 2.1. Induction of Mutator Phenotype; 2.2. Chromosome Translocation; 2.3. Reactive Oxygen Species (ROS); 2.4. Nitric Oxide
2.5. Inhibition of DNA Damage Repair2.6. Oncogenic Activities of the HCV Core Protein; 2.6.1. TNF-α; 2.6.2. MAPK and AP-1; 2.6.3. NF-κB; 2.6.4. Oxidative stress; 2.6.5. Insulin resistance; 2.6.6. PPARα; 2.6.7. Proteasome activator PA28γ; 2.6.8. SOCS-1; 2.6.9. p53; 2.7. Oncogenic Activities of the HCV NS5A Protein; 3. Other Causative Factors in HCV-associated HCC; 3.1. Chronic Liver Inflammation; 3.2. Alcohol; 4. Endoplasmic Reticulum Stress and HCV Pathogenesis; 5. Gene Expression Profile of HCC; 6. HCV and Lymphomagenesis; 6.1. Induction of IgHypermutation by HCV
6.2. Induction of DNA Translocation between IgGenes and Proto-Oncogenes by HCV
Record Nr. UNINA-9910816046903321
New Jersey, : World Scientific, c2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Viral oncology [[electronic resource] ] : basic science and clinical applications / / edited by Kamel Khalili, Kuan-Teh Jeang
Viral oncology [[electronic resource] ] : basic science and clinical applications / / edited by Kamel Khalili, Kuan-Teh Jeang
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Blackwell, c2010
Descrizione fisica 1 online resource (510 p.)
Disciplina 616.99/4019
Altri autori (Persone) KhaliliKamel <1951->
JeangKuan-Teh
Soggetto topico Viral carcinogenesis
Oncogenic viruses
Soggetto genere / forma Electronic books.
ISBN 1-283-91549-9
0-470-93056-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Human papillomavirus-associated cancers / Rachel A. Katzenellenbogin and Denise A. Galloway -- Molecular events associated with human papillomavirus-induced human cancer / Amy Baldwin and Karl Munger -- The role of the human papillomavirus E6 oncoprotein in malignant progression / Miranda Thomas, David Pim, and Lawrence Banks -- JC virus association with brain tumors : the role of T antigen and insulin like growth factor 1 in DNA repair fidelity / Krzysztof Reiss, Kamel Khalili, and Louis Del Valle -- Involvement of the polyomavirus, JC virus in colorectal cancer / C. Richard Boland, Luigi Ricciardiello, and Ajay Goel -- Possible association of BK virus with prostate cancer / Michael J. Imperiale and Dweepanita Das -- Oncogenic transformation by polyomavirus large T antigen / Abhilasha V. Rathi and James M. Pipas -- Simian virus 40, human infections, and cancer : emerging concepts and causality considerations / Janet S. Butel -- Simian virus 40 and mesothelioma / Natalya Baranova and Michele Carbone -- Molecular immunology of hepatitus B-associated viral cancer / Timothy M. Block and Anand S. Mehta -- Hepititis B vaccine and hepatocellular carcinoma / Mei-Hwei Chang and Ding-Shinn Chen -- Pathogenesis of acute and chronic hepatitus C virus infection / Mark A. Feitelson ... [et al.] -- Molecular mechanisms of hepatitis C virus-induced cellular transformation / Donna Sir and Jing-hsiung James Ou -- Clinical aspects of HTLV-1 associated cancer / Masao Matsuoka -- Oncogenic potential of the HTLV-1 tax protein / Susan J. Marriott -- HIV-associated malignancy : basic and clinical aspects / Melissa Agsalda and Bruce Shiramizu -- HIV-related lymphoma / Giulia De Falco ... [et al.] -- Biology and epidemiology of HHV-8 / Veenu Minhas and Charles Wood -- The role of KSHV in pathogenesis of Kaposi's sarcoma / Gary S. Hayward, Donald J. Alcendor, and Ravit Arav-Boger -- Molecular pathobiology of EBV infection / Joseph Pagano -- Epstein-Barr virus as a pathogen / Wasim A. Dar and Bill Sugden.
Record Nr. UNINA-9910459048903321
Hoboken, N.J., : Wiley-Blackwell, c2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Viral oncology [[electronic resource] ] : basic science and clinical applications / / edited by Kamel Khalili, Kuan-Teh Jeang
Viral oncology [[electronic resource] ] : basic science and clinical applications / / edited by Kamel Khalili, Kuan-Teh Jeang
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Blackwell, c2010
Descrizione fisica 1 online resource (510 p.)
Disciplina 616.99/4019
Altri autori (Persone) KhaliliKamel <1951->
JeangKuan-Teh
Soggetto topico Viral carcinogenesis
Oncogenic viruses
ISBN 1-283-91549-9
0-470-93056-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Human papillomavirus-associated cancers / Rachel A. Katzenellenbogin and Denise A. Galloway -- Molecular events associated with human papillomavirus-induced human cancer / Amy Baldwin and Karl Munger -- The role of the human papillomavirus E6 oncoprotein in malignant progression / Miranda Thomas, David Pim, and Lawrence Banks -- JC virus association with brain tumors : the role of T antigen and insulin like growth factor 1 in DNA repair fidelity / Krzysztof Reiss, Kamel Khalili, and Louis Del Valle -- Involvement of the polyomavirus, JC virus in colorectal cancer / C. Richard Boland, Luigi Ricciardiello, and Ajay Goel -- Possible association of BK virus with prostate cancer / Michael J. Imperiale and Dweepanita Das -- Oncogenic transformation by polyomavirus large T antigen / Abhilasha V. Rathi and James M. Pipas -- Simian virus 40, human infections, and cancer : emerging concepts and causality considerations / Janet S. Butel -- Simian virus 40 and mesothelioma / Natalya Baranova and Michele Carbone -- Molecular immunology of hepatitus B-associated viral cancer / Timothy M. Block and Anand S. Mehta -- Hepititis B vaccine and hepatocellular carcinoma / Mei-Hwei Chang and Ding-Shinn Chen -- Pathogenesis of acute and chronic hepatitus C virus infection / Mark A. Feitelson ... [et al.] -- Molecular mechanisms of hepatitis C virus-induced cellular transformation / Donna Sir and Jing-hsiung James Ou -- Clinical aspects of HTLV-1 associated cancer / Masao Matsuoka -- Oncogenic potential of the HTLV-1 tax protein / Susan J. Marriott -- HIV-associated malignancy : basic and clinical aspects / Melissa Agsalda and Bruce Shiramizu -- HIV-related lymphoma / Giulia De Falco ... [et al.] -- Biology and epidemiology of HHV-8 / Veenu Minhas and Charles Wood -- The role of KSHV in pathogenesis of Kaposi's sarcoma / Gary S. Hayward, Donald J. Alcendor, and Ravit Arav-Boger -- Molecular pathobiology of EBV infection / Joseph Pagano -- Epstein-Barr virus as a pathogen / Wasim A. Dar and Bill Sugden.
Record Nr. UNINA-9910784906503321
Hoboken, N.J., : Wiley-Blackwell, c2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Viral oncology : basic science and clinical applications / / edited by Kamel Khalili, Kuan-Teh Jeang
Viral oncology : basic science and clinical applications / / edited by Kamel Khalili, Kuan-Teh Jeang
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Blackwell, c2010
Descrizione fisica 1 online resource (510 p.)
Disciplina 616.99/4019
Altri autori (Persone) KhaliliKamel <1951->
JeangKuan-Teh
Soggetto topico Viral carcinogenesis
Oncogenic viruses
ISBN 1-283-91549-9
0-470-93056-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Human papillomavirus-associated cancers / Rachel A. Katzenellenbogin and Denise A. Galloway -- Molecular events associated with human papillomavirus-induced human cancer / Amy Baldwin and Karl Munger -- The role of the human papillomavirus E6 oncoprotein in malignant progression / Miranda Thomas, David Pim, and Lawrence Banks -- JC virus association with brain tumors : the role of T antigen and insulin like growth factor 1 in DNA repair fidelity / Krzysztof Reiss, Kamel Khalili, and Louis Del Valle -- Involvement of the polyomavirus, JC virus in colorectal cancer / C. Richard Boland, Luigi Ricciardiello, and Ajay Goel -- Possible association of BK virus with prostate cancer / Michael J. Imperiale and Dweepanita Das -- Oncogenic transformation by polyomavirus large T antigen / Abhilasha V. Rathi and James M. Pipas -- Simian virus 40, human infections, and cancer : emerging concepts and causality considerations / Janet S. Butel -- Simian virus 40 and mesothelioma / Natalya Baranova and Michele Carbone -- Molecular immunology of hepatitus B-associated viral cancer / Timothy M. Block and Anand S. Mehta -- Hepititis B vaccine and hepatocellular carcinoma / Mei-Hwei Chang and Ding-Shinn Chen -- Pathogenesis of acute and chronic hepatitus C virus infection / Mark A. Feitelson ... [et al.] -- Molecular mechanisms of hepatitis C virus-induced cellular transformation / Donna Sir and Jing-hsiung James Ou -- Clinical aspects of HTLV-1 associated cancer / Masao Matsuoka -- Oncogenic potential of the HTLV-1 tax protein / Susan J. Marriott -- HIV-associated malignancy : basic and clinical aspects / Melissa Agsalda and Bruce Shiramizu -- HIV-related lymphoma / Giulia De Falco ... [et al.] -- Biology and epidemiology of HHV-8 / Veenu Minhas and Charles Wood -- The role of KSHV in pathogenesis of Kaposi's sarcoma / Gary S. Hayward, Donald J. Alcendor, and Ravit Arav-Boger -- Molecular pathobiology of EBV infection / Joseph Pagano -- Epstein-Barr virus as a pathogen / Wasim A. Dar and Bill Sugden.
Record Nr. UNINA-9910824763803321
Hoboken, N.J., : Wiley-Blackwell, c2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui