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Assessment of planetary protection requirements for spacecraft missions to icy solar system bodies [[electronic resource] /] / Committee on Planetary Protection Standards for Icy Bodies in the Outer Solar System Space Studies Board, Division on Engineering and Physical Sciences, National Research Council of the National Academies
| Assessment of planetary protection requirements for spacecraft missions to icy solar system bodies [[electronic resource] /] / Committee on Planetary Protection Standards for Icy Bodies in the Outer Solar System Space Studies Board, Division on Engineering and Physical Sciences, National Research Council of the National Academies |
| Pubbl/distr/stampa | Washington, D.C., : National Academies Press, c2012 |
| Descrizione fisica | 1 online resource (95 p.) |
| Disciplina | 616.980214 |
| Soggetto topico |
Planets - Exploration
Planets - Exploration - Protection Planets - Water Microbial metabolism Microorganisms - Physiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-63614-X
0-309-25676-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Summary""; ""1 Current Status of Planetary Protection Policies for Icy Bodies""; ""2 Binary Decision Trees""; ""3 Hierarchical Decisions for Planetary Protection""; ""4 A Geophysical Perspective and Inventory of Habitable Environments on Icy Bodies""; ""5 Microbial Metabolism and Physiology""; ""6 Necessary Research""; ""Appendixes""; ""Appendix A: Letter Requesting This Study""; ""Appendix B: Current and Prospective Missions to Icy Bodies of Astrobiological Interest""
""Appendix C: Event Sequence Diagram for the Determination of Planetary Protection Measures for Missions to Icy Bodies""""Appendix D: Committee and Staff Biographical Information""; ""Appendix E: Glossary and Abbreviations"" |
| Record Nr. | UNINA-9910462334103321 |
| Washington, D.C., : National Academies Press, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Assessment of planetary protection requirements for spacecraft missions to icy solar system bodies [[electronic resource] /] / Committee on Planetary Protection Standards for Icy Bodies in the Outer Solar System Space Studies Board, Division on Engineering and Physical Sciences, National Research Council of the National Academies
| Assessment of planetary protection requirements for spacecraft missions to icy solar system bodies [[electronic resource] /] / Committee on Planetary Protection Standards for Icy Bodies in the Outer Solar System Space Studies Board, Division on Engineering and Physical Sciences, National Research Council of the National Academies |
| Pubbl/distr/stampa | Washington, D.C., : National Academies Press, c2012 |
| Descrizione fisica | 1 online resource (95 p.) |
| Disciplina | 616.980214 |
| Soggetto topico |
Planets - Exploration
Planets - Exploration - Protection Planets - Water Microbial metabolism Microorganisms - Physiology |
| ISBN |
0-309-25678-X
1-283-63614-X 0-309-25676-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Summary""; ""1 Current Status of Planetary Protection Policies for Icy Bodies""; ""2 Binary Decision Trees""; ""3 Hierarchical Decisions for Planetary Protection""; ""4 A Geophysical Perspective and Inventory of Habitable Environments on Icy Bodies""; ""5 Microbial Metabolism and Physiology""; ""6 Necessary Research""; ""Appendixes""; ""Appendix A: Letter Requesting This Study""; ""Appendix B: Current and Prospective Missions to Icy Bodies of Astrobiological Interest""
""Appendix C: Event Sequence Diagram for the Determination of Planetary Protection Measures for Missions to Icy Bodies""""Appendix D: Committee and Staff Biographical Information""; ""Appendix E: Glossary and Abbreviations"" |
| Record Nr. | UNINA-9910785511803321 |
| Washington, D.C., : National Academies Press, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Assessment of planetary protection requirements for spacecraft missions to icy solar system bodies [[electronic resource] /] / Committee on Planetary Protection Standards for Icy Bodies in the Outer Solar System Space Studies Board, Division on Engineering and Physical Sciences, National Research Council of the National Academies
| Assessment of planetary protection requirements for spacecraft missions to icy solar system bodies [[electronic resource] /] / Committee on Planetary Protection Standards for Icy Bodies in the Outer Solar System Space Studies Board, Division on Engineering and Physical Sciences, National Research Council of the National Academies |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academies Press, c2012 |
| Descrizione fisica | 1 online resource (95 p.) |
| Disciplina | 616.980214 |
| Soggetto topico |
Planets - Exploration
Planets - Exploration - Protection Planets - Water Microbial metabolism Microorganisms - Physiology |
| ISBN |
0-309-25678-X
1-283-63614-X 0-309-25676-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Summary""; ""1 Current Status of Planetary Protection Policies for Icy Bodies""; ""2 Binary Decision Trees""; ""3 Hierarchical Decisions for Planetary Protection""; ""4 A Geophysical Perspective and Inventory of Habitable Environments on Icy Bodies""; ""5 Microbial Metabolism and Physiology""; ""6 Necessary Research""; ""Appendixes""; ""Appendix A: Letter Requesting This Study""; ""Appendix B: Current and Prospective Missions to Icy Bodies of Astrobiological Interest""
""Appendix C: Event Sequence Diagram for the Determination of Planetary Protection Measures for Missions to Icy Bodies""""Appendix D: Committee and Staff Biographical Information""; ""Appendix E: Glossary and Abbreviations"" |
| Record Nr. | UNINA-9910808358603321 |
| Washington, D.C., : National Academies Press, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biology in space and life on earth [[electronic resource] ] : effects of spaceflight on biological systems / / edited by Enno Brinckmann
| Biology in space and life on earth [[electronic resource] ] : effects of spaceflight on biological systems / / edited by Enno Brinckmann |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2007 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
571.0919
616.980214 |
| Altri autori (Persone) | BrinckmannEnno |
| Soggetto topico |
Space biology
Space flight - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-23932-1
9786611239329 3-527-61700-0 3-527-61699-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biology in Space and Life on Earth; Contents; Foreword; Preface; List of Contributors; Introduction; 1 Flight Mission Scenarios; 2 Sounding Rocket Experiments; 3 Biobox on Foton and in the Space Shuttle; 3.1 Biobox-1; 3.2 Biobox-2; 3.3 Biobox-3; 3.4 Biobox-4; 4 Biorack in Spacelab and Spacehab; 1 The Gravity Environment in Space Experiments; 1.1 Introduction to Gravity Research; 1.1.1 Principle of Equivalence; 1.1.2 Microgravity; 1.1.3 Artificial Gravity; 1.2 Gravity Phenomena on Small Objects; 1.2.1 Sedimentation; 1.2.2 Hydrostatic Pressure; 1.2.3 Diffusion; 1.2.4 Convection
1.2.5 Diffusion/Convection1.2.6 Buoyancy; 1.2.7 Coriolis Acceleration; 2 Primary Responses of Gravity Sensing in Plants; 2.1 Introduction and Historical Background; 2.2 Evolution of Gravity Sensing Mechanisms under the Earth's Gravity Conditions; 2.3 Specific Location and Unique Features of Gravity Sensing Cells; 2.4 Correlation between Statolith Sedimentation and Gravitropic Responses; 2.5 Is the Actin Cytoskeleton Involved in Gravity Sensing?; 2.6 Gravireceptors; 2.7 Second Messengers in Gravisignalling 2.8 Modifying Gravitational Acceleration Forces - Versatile Tools for Studying Plant Gravity Sensing Mechanisms2.9 Conclusions and Perspectives; 3 Physiological Responses of Higher Plants; 3.1 Introduction: Historical Overview; 3.2 Terminological Aspects; 3.3 Microgravity as a Tool; 3.3.1 Equipment; 3.3.2 Testable Hypotheses; 3.3.2.1 Gravisensitivity; 3.3.2.2 Stimulus Transformation: Role of the Actomyosin System; 3.3.2.3 Extracellular Matrix as Anti-gravitational Material; 3.3.2.4 Existence of Gravity (Microgravity) Related Genes; 3.3.2.5 Autonomous versus Directed Movements 3.4 Microgravity as Stress Factor3.4.1 Cellular Level; 3.4.2 Developmental Aspects; 3.5 Gravity-related Paradoxes; 3.6 Gravity and Evolution; 3.7 Conclusion and Perspectives; 4 Development and Gravitropism of Lentil Seedling Roots Grown in Microgravity; 4.1 Introduction; 4.1.1 Development of Lentil Seedlings on the Ground; 4.1.1.1 Functional Zones of the Primary Root; 4.1.1.2 Role of the Root Cap; 4.1.1.3 Meristematic Activity; 4.1.1.4 Cell Elongation; 4.1.2 Root Gravitropism on Earth; 4.1.2.1 Perception of Gravity; 4.1.2.2 The Root Statocyte; 4.1.2.3 Gravisensitivity: The Presentation Time 4.1.2.4 Gravitropic Reaction4.2 Basic Hardware Used to Perform Space Experiments; 4.2.1 Plant Growth Chambers: The Minicontainers; 4.2.1.1 Seed Set-up; 4.2.1.2 Hydration of the Seeds; 4.2.2 The Glutaraldehyde Fixer; 4.3 Development in Space; 4.3.1 Root Orientation in Microgravity; 4.3.2 Root Growth; 4.3.3 Cell Elongation; 4.3.4 Meristematic Activity; 4.3.4.1 Mitotic Activity; 4.3.4.2 Cell Cycle; 4.4 Root Gravitropism in Space; 4.4.1 Organelle Distribution within the Statocyte; 4.4.1.1 Statocyte Polarity; 4.4.1.2 Positioning of the Nucleus and of the Endoplasmic Reticulum 4.4.1.3 Amyloplasts Positioning |
| Record Nr. | UNINA-9910144732903321 |
| Weinheim, : Wiley-VCH, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biology in space and life on earth [[electronic resource] ] : effects of spaceflight on biological systems / / edited by Enno Brinckmann
| Biology in space and life on earth [[electronic resource] ] : effects of spaceflight on biological systems / / edited by Enno Brinckmann |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2007 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
571.0919
616.980214 |
| Altri autori (Persone) | BrinckmannEnno |
| Soggetto topico |
Space biology
Space flight - Physiological effect |
| ISBN |
1-281-23932-1
9786611239329 3-527-61700-0 3-527-61699-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biology in Space and Life on Earth; Contents; Foreword; Preface; List of Contributors; Introduction; 1 Flight Mission Scenarios; 2 Sounding Rocket Experiments; 3 Biobox on Foton and in the Space Shuttle; 3.1 Biobox-1; 3.2 Biobox-2; 3.3 Biobox-3; 3.4 Biobox-4; 4 Biorack in Spacelab and Spacehab; 1 The Gravity Environment in Space Experiments; 1.1 Introduction to Gravity Research; 1.1.1 Principle of Equivalence; 1.1.2 Microgravity; 1.1.3 Artificial Gravity; 1.2 Gravity Phenomena on Small Objects; 1.2.1 Sedimentation; 1.2.2 Hydrostatic Pressure; 1.2.3 Diffusion; 1.2.4 Convection
1.2.5 Diffusion/Convection1.2.6 Buoyancy; 1.2.7 Coriolis Acceleration; 2 Primary Responses of Gravity Sensing in Plants; 2.1 Introduction and Historical Background; 2.2 Evolution of Gravity Sensing Mechanisms under the Earth's Gravity Conditions; 2.3 Specific Location and Unique Features of Gravity Sensing Cells; 2.4 Correlation between Statolith Sedimentation and Gravitropic Responses; 2.5 Is the Actin Cytoskeleton Involved in Gravity Sensing?; 2.6 Gravireceptors; 2.7 Second Messengers in Gravisignalling 2.8 Modifying Gravitational Acceleration Forces - Versatile Tools for Studying Plant Gravity Sensing Mechanisms2.9 Conclusions and Perspectives; 3 Physiological Responses of Higher Plants; 3.1 Introduction: Historical Overview; 3.2 Terminological Aspects; 3.3 Microgravity as a Tool; 3.3.1 Equipment; 3.3.2 Testable Hypotheses; 3.3.2.1 Gravisensitivity; 3.3.2.2 Stimulus Transformation: Role of the Actomyosin System; 3.3.2.3 Extracellular Matrix as Anti-gravitational Material; 3.3.2.4 Existence of Gravity (Microgravity) Related Genes; 3.3.2.5 Autonomous versus Directed Movements 3.4 Microgravity as Stress Factor3.4.1 Cellular Level; 3.4.2 Developmental Aspects; 3.5 Gravity-related Paradoxes; 3.6 Gravity and Evolution; 3.7 Conclusion and Perspectives; 4 Development and Gravitropism of Lentil Seedling Roots Grown in Microgravity; 4.1 Introduction; 4.1.1 Development of Lentil Seedlings on the Ground; 4.1.1.1 Functional Zones of the Primary Root; 4.1.1.2 Role of the Root Cap; 4.1.1.3 Meristematic Activity; 4.1.1.4 Cell Elongation; 4.1.2 Root Gravitropism on Earth; 4.1.2.1 Perception of Gravity; 4.1.2.2 The Root Statocyte; 4.1.2.3 Gravisensitivity: The Presentation Time 4.1.2.4 Gravitropic Reaction4.2 Basic Hardware Used to Perform Space Experiments; 4.2.1 Plant Growth Chambers: The Minicontainers; 4.2.1.1 Seed Set-up; 4.2.1.2 Hydration of the Seeds; 4.2.2 The Glutaraldehyde Fixer; 4.3 Development in Space; 4.3.1 Root Orientation in Microgravity; 4.3.2 Root Growth; 4.3.3 Cell Elongation; 4.3.4 Meristematic Activity; 4.3.4.1 Mitotic Activity; 4.3.4.2 Cell Cycle; 4.4 Root Gravitropism in Space; 4.4.1 Organelle Distribution within the Statocyte; 4.4.1.1 Statocyte Polarity; 4.4.1.2 Positioning of the Nucleus and of the Endoplasmic Reticulum 4.4.1.3 Amyloplasts Positioning |
| Record Nr. | UNINA-9910830921803321 |
| Weinheim, : Wiley-VCH, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biology in space and life on earth [[electronic resource] ] : effects of spaceflight on biological systems / / edited by Enno Brinckmann
| Biology in space and life on earth [[electronic resource] ] : effects of spaceflight on biological systems / / edited by Enno Brinckmann |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2007 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
571.0919
616.980214 |
| Altri autori (Persone) | BrinckmannEnno |
| Soggetto topico |
Space biology
Space flight - Physiological effect |
| ISBN |
1-281-23932-1
9786611239329 3-527-61700-0 3-527-61699-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biology in Space and Life on Earth; Contents; Foreword; Preface; List of Contributors; Introduction; 1 Flight Mission Scenarios; 2 Sounding Rocket Experiments; 3 Biobox on Foton and in the Space Shuttle; 3.1 Biobox-1; 3.2 Biobox-2; 3.3 Biobox-3; 3.4 Biobox-4; 4 Biorack in Spacelab and Spacehab; 1 The Gravity Environment in Space Experiments; 1.1 Introduction to Gravity Research; 1.1.1 Principle of Equivalence; 1.1.2 Microgravity; 1.1.3 Artificial Gravity; 1.2 Gravity Phenomena on Small Objects; 1.2.1 Sedimentation; 1.2.2 Hydrostatic Pressure; 1.2.3 Diffusion; 1.2.4 Convection
1.2.5 Diffusion/Convection1.2.6 Buoyancy; 1.2.7 Coriolis Acceleration; 2 Primary Responses of Gravity Sensing in Plants; 2.1 Introduction and Historical Background; 2.2 Evolution of Gravity Sensing Mechanisms under the Earth's Gravity Conditions; 2.3 Specific Location and Unique Features of Gravity Sensing Cells; 2.4 Correlation between Statolith Sedimentation and Gravitropic Responses; 2.5 Is the Actin Cytoskeleton Involved in Gravity Sensing?; 2.6 Gravireceptors; 2.7 Second Messengers in Gravisignalling 2.8 Modifying Gravitational Acceleration Forces - Versatile Tools for Studying Plant Gravity Sensing Mechanisms2.9 Conclusions and Perspectives; 3 Physiological Responses of Higher Plants; 3.1 Introduction: Historical Overview; 3.2 Terminological Aspects; 3.3 Microgravity as a Tool; 3.3.1 Equipment; 3.3.2 Testable Hypotheses; 3.3.2.1 Gravisensitivity; 3.3.2.2 Stimulus Transformation: Role of the Actomyosin System; 3.3.2.3 Extracellular Matrix as Anti-gravitational Material; 3.3.2.4 Existence of Gravity (Microgravity) Related Genes; 3.3.2.5 Autonomous versus Directed Movements 3.4 Microgravity as Stress Factor3.4.1 Cellular Level; 3.4.2 Developmental Aspects; 3.5 Gravity-related Paradoxes; 3.6 Gravity and Evolution; 3.7 Conclusion and Perspectives; 4 Development and Gravitropism of Lentil Seedling Roots Grown in Microgravity; 4.1 Introduction; 4.1.1 Development of Lentil Seedlings on the Ground; 4.1.1.1 Functional Zones of the Primary Root; 4.1.1.2 Role of the Root Cap; 4.1.1.3 Meristematic Activity; 4.1.1.4 Cell Elongation; 4.1.2 Root Gravitropism on Earth; 4.1.2.1 Perception of Gravity; 4.1.2.2 The Root Statocyte; 4.1.2.3 Gravisensitivity: The Presentation Time 4.1.2.4 Gravitropic Reaction4.2 Basic Hardware Used to Perform Space Experiments; 4.2.1 Plant Growth Chambers: The Minicontainers; 4.2.1.1 Seed Set-up; 4.2.1.2 Hydration of the Seeds; 4.2.2 The Glutaraldehyde Fixer; 4.3 Development in Space; 4.3.1 Root Orientation in Microgravity; 4.3.2 Root Growth; 4.3.3 Cell Elongation; 4.3.4 Meristematic Activity; 4.3.4.1 Mitotic Activity; 4.3.4.2 Cell Cycle; 4.4 Root Gravitropism in Space; 4.4.1 Organelle Distribution within the Statocyte; 4.4.1.1 Statocyte Polarity; 4.4.1.2 Positioning of the Nucleus and of the Endoplasmic Reticulum 4.4.1.3 Amyloplasts Positioning |
| Record Nr. | UNINA-9910841179403321 |
| Weinheim, : Wiley-VCH, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cardiovascular complications of COVID-19 : acute and long-term impacts / / edited by Maciej Banach
| Cardiovascular complications of COVID-19 : acute and long-term impacts / / edited by Maciej Banach |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (434 pages) |
| Disciplina | 616.980214 |
| Collana | Contemporary Cardiology |
| Soggetto topico |
Cardiovascular system - Diseases
COVID-19 (Disease) - Complications |
| ISBN |
9783031154782
9783031154775 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Part I: General Part -- Chapter 1: Biology of SARS-CoV-2 Coronavirus -- Origin, Structure, and Variants -- Introduction -- Method of Search -- The SARS-CoV-2 Biology -- The SARS-CoV-2 Origins -- HCoV-229E -- HCoV-OC43 -- SARS-CoV -- HCoV-NL63 -- HCoV-HKU1 -- MERS-CoV -- SARS-CoV-2 -- The SARS-CoV-2 Structure -- SARS-CoV-2 Variants -- Conclusion -- References -- Chapter 2: COVID-19 Epidemiology and Differences in Incidence and Mortality Between Countries -- Origins -- Asian Countries -- COVID-19 in the United States of America -- Canada -- Mexico -- Peru -- Brazil -- Colombia -- Europe -- Russia -- Ukraine -- Italy -- Poland -- South Africa -- Antarctica -- References -- Chapter 3: Clinical Symptoms and Course of COVID-19 -- SARS-CoV-2 Transmission -- Virus Replication -- Immunological Responses and Cytokine Storm (CS) -- Virus Variants and Associated Evolution in the Clinical Course -- Clinical Stages of COVID-19 [21] -- Mild and Asymptomatic Stage -- Symptomatic Stage -- Severe Disease -- Acute Respiratory Distress Syndrome/Critical Stage -- Clinical Symptoms of COVID-19 -- General Symptoms in the Early, Asymptomatic and Mild Infection -- Respiratory Manifestations -- Extra-Respiratory Manifestations -- Hematologic Abnormalities -- Prothrombotic Events -- Cardiovascular Involvement -- Neurological and Neuropsychiatric Manifestations -- Kidney Involvement -- Gastrointestinal and Hepatic Involvement -- Skin Associated COVID-19 Symptoms -- COVID-19 in Children -- Long COVID-19 -- Conclusions -- References -- Chapter 4: Risk Factors of Developing COVID-19 and its Severe Course -- COVID-19 and Related Cardiovascular Risk Factors -- Age -- Sex -- Smoking -- Diabetes -- Obesity -- Hypertension -- Dyslipidemia -- Chronic Kidney Disease.
Additional Markers of Increased CV Disease Risk in COVID-19 -- References -- Chapter 5: Prognosis in COVID-19 Patients: Statistics, Risk Factors -- Introduction -- Demographic Features -- Age and Sex -- Ethnicity -- Clinical Symptoms -- Comorbidities and the Course of COVID-19 -- Hypertension -- Diabetes Mellitus -- Obesity -- Chronic Obstructive Pulmonary Disease (COPD) -- Chronic Kidney Disease -- Cancer -- Special Conditions and Populations of Patients and the COVID-19 Course -- Smoking -- Pregnancy -- Children -- Selected Laboratory Parameters Values and the COVID-19 Course -- Leukocyte Counts -- Lymphocyte Counts -- Neutrophil Counts -- Platelet Counts -- C-Reactive Protein (CRP) -- Procalcitonin (PCT) -- Lactate Dehydrogenase (LDH) -- Interleukin 6 (IL-6) -- D-Dimer -- Ferritin -- Albumin -- Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) -- Cardiac Troponin -- Complications -- Reinfection -- Conclusions and Take-Home Message -- References -- Part II: Cardiovascular Complications of the Acute Phase of COVID-19 -- Chapter 6: Myocardial Injury in COVID-19 (Epidemiology, Influence on Prognosis, Pathogenesis, Treatment) -- Introduction -- Definition of COVID-19 Induced Myocardial Injury -- Epidemiology -- Pathogenesis of Myocardial Injury in COVID-19 Patients -- Biomarkers Assessment of Myocardial Injury -- Cardiac Troponin -- Myocardial and Systemic Inflammation -- Other Biomarkers -- Paraclinical Assessment of Myocardial Injury -- ECG -- Cardiac Ultrasound -- Coronary Angiography -- Computed Tomography Angiography (CTA) -- Cardiac MRI -- Follow-Up and Treatment -- Prognosis -- Conclusions -- References -- Chapter 7: Acute Coronary Syndrome: Destabilization of Atherosclerotic Plaque in COVID-19 (Epidemiology, Influence on Prognosis, Pathogenesis, and Treatment). COVID-19: Short Clinical Characteristics Through the Prism of Cardiology -- Epidemiology and Risk of ACS During SARS-CoV-2 Infection -- ACS During SARS-CoV-2 Infection and Prognosis -- Pathogenesis of ACS Induced by SARS-CoV-2 Infection -- Diagnostics and Treatment Aspects -- STEMI: ESC Guidance for the Diagnosis and Management of Cardiovascular Disease During the COVID-19 Pandemic [101] -- NSTEMI: ESC Guidance for the Diagnosis and Management of Cardiovascular Disease During the COVID-19 Pandemic [101] -- ACS Prevention -- Conclusions -- References -- Chapter 8: Acute Vascular Injury in COVID-19 -- Introduction -- Pathophysiology -- Clinical Presentation -- Respiratory -- Cardiovascular -- Central Nervous System -- Gastrointestinal -- Renal -- Dermatological -- Systemic Vasculitis -- Vaccine-Related Complications -- Treatment -- Anticoagulation -- Acute Coronary Syndrome -- Ischemic Stroke -- Venous Thromboembolism, DVT, and PE -- Acute Limb Ischemia -- Prophylaxis -- Anticoagulation -- Anti-Inflammatory Therapies -- Statins -- RAAS Inhibition -- Conclusion -- References -- Chapter 9: Heart Failure and Acute Circulatory Failure in COVID-19 (Epidemiology, Influence on Prognosis, Pathogenesis, Treatment) -- Epidemiology -- Influence on Prognosis -- Pre-existing HF -- New Onset of HF -- Cardiogenic Shock -- Pathogenesis -- Direct Injury -- Systemic Inflammation -- Hypoxic Injury -- Endothelial Dysfunction-Induced Coagulation Disorders -- Treatment -- Chronic Heart Failure Treatment -- Acute Heart Failure Treatment -- References -- Chapter 10: Cardiomyopathy in COVID-19 (Epidemiology, Influence on Prognosis, Pathogenesis, Treatment) -- Introduction -- Heart Failure, Cardiomyopathies and COVID-19 -- Stress-Induced Cardiomyopathy and COVID-19 -- Dilated Cardiomyopathy and COVID-19 -- Hypertrophic Cardiomyopathy. Restrictive Cardiomyopathy and Arrhythmogenic Right Ventricular Cardiomyopathy in COVID-19 -- Cardiomyopathies and COVID-19 Vaccines -- Summary -- References -- Chapter 11: Arrhythmias in COVID-19 -- Epidemiology -- Influence on Prognosis -- Pathogenesis -- Treatment -- References -- Chapter 12: Thromboembolic Events in COVID-19 -- Epidemiology -- Pathogenesis -- The Diagnosis of VTE in COVID-19 -- Treatment -- Thromboprophylaxis in Patients with COVID-19 -- Influence on Prognosis -- Conclusions -- References -- Chapter 13: Stroke in COVID-19 -- Introduction -- Ischemic Stroke (IS) and Transient Ischemic Attack (TIA) in COVID-19 Pandemic -- Epidemiology of IS and TIA During COVID-19 Pandemic -- Description of IS in COVID-19 Positive Patients -- Clinical, Etiological, and Imaging Features of COVID-19 Positive IS Patients -- Management of COVID-19 Positive Patients with IS -- Outcome of COVID-19 Positive Patients with IS -- Pathogenesis -- Conclusions -- Hemorrhagic Stroke (HS) in COVID-19 Pandemic -- Epidemiology of HS During COVID-19 Pandemic -- Intracerebral Hemorrhage (ICH) -- Clinical Features of ICH in COVID-19 Positive Patients -- Comorbidities of COVID-19 Positive Patients with ICH -- Management of COVID-19 Positive Patients with ICH -- Course and Outcome of HS in COVID-19 Positive Patients -- Pathogenesis -- Conclusion -- Subarachnoid Hemorrhage (SAH) in COVID-19 Pandemic -- Epidemiology During COVID-19 Pandemic -- Clinical Features of COVID-19 Positive SAH Patients -- Course and Outcome of COVID-19 Positive Patients with SAH -- Pathogenesis -- Conclusion -- Cerebral Venous Thrombosis (CVT) in COVID-19 Positive Patients -- Epidemiology of CVT During COVID-19 Pandemic -- Clinical Features of CVT in COVID-19 Positive Patients -- Course and Outcome of CVT in COVID-19 Positive Patients -- Pathogenesis -- Conclusion -- References. Chapter 14: Pulmonary Embolism After COVID-19 (Epidemiology, Influence on Prognosis, Pathogenesis, Treatment) -- Introduction -- Epidemiology -- Incidence, Risk Factors -- Pathogenesis -- Thromboembolic Event Prevention and Management in COVID-19 Pneumonia Patients -- Prophylactic Anticoagulation in Severe Hospitalized Patients -- Prophylactic Anticoagulation in Mild to Moderate Patients -- Prophylactic Treatment in Outpatient -- Anticoagulation After Discharge from COVID-19 Hospitalization -- Therapeutic Anticoagulation of Incident Thromboembolism Event -- Medium- and Long-Term Prognosis After a Venous Thrombotic Event -- Conclusion -- References -- Chapter 15: Interaction of Anti-COVID-19 Drugs with Cardiovascular Therapy -- Statins -- β-Blockers -- Antihypertensive Drugs -- Natural Drugs -- References -- Part III: Influence of the Treatment of Cardiovascular Diseases on the Course of COVID-19 -- Chapter 16: Beyond the Vaccines-Bioactive Lipids in COVID-19 -- Introduction -- Bioactive Lipids LA and AA Can Inactivate SARS-CoV-2 -- Immunocytes and AA -- M1 and M2 Macrophages and Lipids -- Interaction(s) Among Desaturases, COX, LOX, n-3, and n-6 Fatty Acids and Their Metabolites and Cytokines -- PGE2 and LXA4 Interact with each Other to Control Inflammation and Its Resolution -- Conclusions and Therapeutic Implications -- References -- Chapter 17: Statins and COVID-19 (Mechanism of Action, Effect on Prognosis) -- Statins and COVID-19: Mechanism of Action -- Direct Effect of Statins -- Indirect Effect of Statins -- Statins and COVID-19: Effect on Prognosis -- COVID-19 and Familial Hypercholesterolemia -- References -- Chapter 18: COVID-19 and Antihypertensive Treatment -- Introduction -- COVID-19 and Hypertension -- COVID-19 and Antihypertensive Drug Treatment -- Study Limitations -- Blood Pressure Values, Blood Pressure Control, and COVID-19 Pandemic. COVID-19 and Hypertension Guidelines. |
| Record Nr. | UNINA-9910637709603321 |
| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Exercise in Space [[electronic resource] ] : A Holistic Approach for the Benefit of Human Health on Earth / / edited by Stefan Schneider
| Exercise in Space [[electronic resource] ] : A Holistic Approach for the Benefit of Human Health on Earth / / edited by Stefan Schneider |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (124 p.) |
| Disciplina | 616.980214 |
| Collana | SpringerBriefs in Space Life Sciences |
| Soggetto topico |
Human physiology
Aerospace engineering Astronautics Sports medicine Neurosciences Public health Human Physiology Aerospace Technology and Astronautics Sports Medicine Public Health |
| ISBN | 3-319-29571-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Motor skills -- Adaptation of cartilage to immobilization -- Influence of Weightlessness on Aerobic Capacity, Cardiac Output and Oxygen Uptake Kinetics -- Enhancing mental health: Effects of exercise on social well-being and social ill-being -- Neurocognitive and neuro-affective effects of exercise. |
| Record Nr. | UNINA-9910253890303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of space pharmaceuticals / / Yashwant V. Pathak, Marlise Araújo dos Santos and Luis Zea, editors
| Handbook of space pharmaceuticals / / Yashwant V. Pathak, Marlise Araújo dos Santos and Luis Zea, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (1036 pages) |
| Disciplina | 616.980214 |
| Soggetto topico |
Space medicine
Pharmaceutical industry Space flight - Health aspects |
| ISBN | 3-030-05526-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- About the Editors -- Contributors -- Part I: Principles of Pharmaceuticals -- 1 Introduction to Pharmaceuticals -- Introduction -- Early Days of Drugs and Dosage Forms: The Heritage of Pharmacy -- Period of Scientific Research -- Pharmaceuticals in Modern Perspective -- Pharmaceuticals as Drug Products, Drug Delivery Systems, and Therapeutic Systems -- Brief Introduction to Dosage Forms -- Solid Oral Dosage Forms -- Liquid Dosage Forms: Solutions and Dispersed Systems -- Oral Solutions, Syrups, Elixirs, Spirits, and Tinctures -- Topical Formulations: Semisolid Dosage Forms: Ointments, Creams, Gels, Jellies, Lotions, Pastes, and Foams -- Powders and Granules -- Dosage Forms and Drug Delivery for Specific Routes of Administration -- Novel Drug Delivery Systems and Devices -- Challenges in Using Pharmaceuticals in Space -- Drugs Used During the Spaceflights for the Astronauts -- An Overview -- Impact of Spaceflight on the Human Body -- Pharmacokinetic and Pharmacodynamic Changes -- Conclusion -- References -- 2 Understanding the Routes of Administration -- Oral Route of Administration -- Pathophysiology of Epithelial Barrier -- Buccal Cavity -- Stomach -- Small Intestine -- Large Intestine -- Physicochemical Properties of Drugs -- Dissolution and Solubility -- Lipophilicity-Permeability -- Other Factors -- Absorption Mechanism -- Applications and Examples -- Parenteral Route of Administration -- Intravenous (IV) Injection -- Intramuscular (IM) Injection -- Subcutaneous (SC) Injection -- Intradermal (ID) Injection -- Topical and Transdermal Administration -- Ophthalmic Administration -- Buccal and Sublingual -- Rectal and Vaginal -- Inhalational -- Conclusion -- References -- 3 Physicochemical Basic Principles for Solid Dosage Forms -- Introduction.
Polymorphism in Solid Dosage Forms: Crystalline and Amorphous States -- Size Matters: Particle Size Properties -- Morphological Evaluation of Solid Dosage Forms: A Nanoperspective -- Solid-State Stability of the Component Actives and Excipients -- Hygroscopicity and Hydroactivity -- Solubility Aspects -- Dissolution Properties -- Future Developments in the Design of Solid Dosage Forms -- References -- 4 Physicochemical Basic Principles for Liquid Dosage Forms -- Terms Used -- Liquid Formulations -- Liquids for Internal Use -- Syrups -- Elixirs -- Drops -- Intravenous Solutions/Fluids -- Liquids for External Use -- Liniment or Balm -- Lotion -- Tincture -- Physiochemical Properties of Active Pharmaceutical Ingredient (API) in LDFS -- Solubility -- Factors Affecting Solubility of API -- pKa/Dissociation Constants -- Partition Coefficient -- Effects of Physicochemical Properties on Manufacturing Processes -- Future Directions and Conclusion -- References -- 5 Solid Dosage Forms: Formulation and Characterization -- Introduction and Need of Solid Dosage Forms for Space Pharmaceuticals -- The Physiological Changes in the Space and Available Solid Dosage Form as Space Pharmaceuticals -- Formulation of Space Pharmaceuticals -- Challenges for a Solid Dosage in Context of Stability in Space -- Stability, Formulation, and Characterization Challenges -- Comparison of Solid Dosage Forms with Other Dosage Forms for Space Pharmaceuticals -- Solid Dosage Form Design for Space (Gibson 2009) -- Future of the Medical Treatment and the Pharmaceuticals in Space -- References -- 6 Pharmaceutical Liquid Dosage Forms in Space: Looking Toward the Future by Learning from the Past -- Introduction -- Pharmaceutical Formulations in Space Missions -- The Types of Pharmaceutical Formulations: Solid, Semisolid, and Liquid Dosage Forms. General Properties of Pharmaceutical Formulations -- Liquid Dosage Formulations -- Pharmaceutical Liquid Dosage Forms: Solutions, Suspensions, Colloids, and Emulsions -- Pharmaceutical Solutions -- Types of Pharmaceutical Solutions -- Physical and Chemical Characteristics of Pharmaceutical Solutions -- The Medical Use of Pharmaceutical Solutions -- The Effect of Space on the Stability of Solutions -- Mechanism of Space-Based Degradation of Pharmaceutical Solutions -- Pharmaceutical Suspensions -- Types of Pharmaceutical Suspensions -- Physical and Chemical Characteristics of Pharmaceutical Suspensions -- The Medical Use of Pharmaceutical Suspensions -- The Effect of Space on the Stability of Suspensions -- Liquid Dosage Forms and Space Travel: Overall Considerations -- Fluids and Microgravity Influence on Physical Systems -- Pharmaceutical Product Stability and Shelf Life -- Physical Factors Affecting Phenomena Associated with Pharmaceutical Solutions and Suspensions -- Conclusion -- References -- 7 Nano Drug Delivery Systems for Space Applications -- Biopharmaceutical Challenges of Therapeutics in Space -- Necessity for Nanoparticle-Based Drug Formulations -- Nanotechnology Approach for Space Medicine -- Innovative Means for Drug Delivery -- Constant Drug Delivery Nanotechnologies for Space Exploration -- Applications of Nano-Gland for Space Medicine -- Bionano Scaffolds (BNS) as a Space Nanomedicine -- Nanomedical Devices for Loss of Bone Density and Mass Under Microgravity -- Carbon Nanotubes for Cardiac Function and Muscle Atrophy -- Dendrimeric Nanodevice for Detection of Cellular Damage in Astronauts -- Targeted Nanoparticles to Alleviate Microgravity-Induced Ocular Anomalies -- Polymeric Nanofiber Scaffolds to Prevent or Counteract the Deleterious Effects of Microgravity on the Brain and DNA -- Quantum Dots for Diagnostic Testing. Grapheme-Based Nanocomposites -- Gold Nanoparticles for Biomedical Application -- Conclusion -- References -- 8 Basic Principles of Biopharmaceutics and Pharmacokinetics During Spaceflight -- Introduction -- Basic Principles of Pharmacokinetics -- Clearance -- Volume of Distribution -- Half-Life -- Bioavailability -- Absorption -- Factors Affecting Absorption -- Dissolution Rate -- Gastric Emptying and Intestinal Transit -- Presystemic Metabolism -- Studies of Spaceflight Impact on Absorption -- Inflight Studies of Drug Absorption -- Simulated Microgravity Studies of Drug Absorption -- Distribution -- Factors Affecting Distribution -- Fluid Shift -- Protein Binding in the Blood -- Protein Binding in Tissue -- Studies of Spaceflight Impact on Distribution -- Simulated Microgravity Studies of Drug Distribution -- Metabolism and Excretion -- Factors Affecting Metabolism and Excretion -- Intrinsic Clearance -- Protein Binding -- Blood Flow -- Other Routes of Elimination -- Studies of Spaceflight Impact on Metabolism and Excretion -- Inflight Studies of Drug Metabolism and Excretion -- Simulated Microgravity Studies of Drug Metabolism and Excretion: Bed Rest -- Simulated Microgravity Studies of Drug Metabolism and Excretion: Tail-Suspended Rat Model -- Conclusion -- References -- 9 Medications in Microgravity: History, Facts, and Future Trends -- Where Did We Begin? -- Evolution of the Medical Kit -- The Medical Kit -- Medical Incidents and Frequency -- Dose Response -- Routes of Administration -- Multiple Causes -- Future Recommendations -- Ground Research Models -- References -- 10 Evaluation of Physical and Chemical Changes in Pharmaceuticals Flown on Space Missions -- Causes of Physical and Chemical Changes -- Radiation Effects -- Cumulative Radiation Dose -- Low-Earth Orbits -- High-Earth Orbits and Beyond -- Physical Changes Due to Radiation. Thermal Considerations -- Magnetic and Electric Field Effects -- Effects of Acceleration -- Effects on Storage Containers -- Effects on the Medication -- Effects of Vibration -- Effects of Freefall -- Atmospheric Conditions -- Decomposition and Degradation -- Packaging and Coating -- Container Degradation -- Glass -- Polymers -- Realized Changes from Experimentation -- Space Transportation System (Du et al. 2011) -- Methodology -- Analysis -- Results -- Physical Changes -- Chemical Changes -- The Effects of Environmental Factors -- Characteristics of Longevity -- International Space Station (Wotring 2016) -- Specific Drug Susceptibility -- Manufacturing Pharmaceuticals for Space -- References -- 11 Implications of Microgravity on Microemulsions and Nanoemulsions -- Microemulsions, Nanoemulsions, and Types of Formulations -- Some Considerations of Microemulsions or Nanoemulsions and Pharmacokinetics in Microgravity -- What Can Be Expected -- Future Considerations -- References -- 12 Three-Dimensional Printing (3DP) for Space Pharmaceuticals -- Introduction -- 3DP Techniques and Potential Opportunities in Space Pharmaceuticals -- Material Jetting - Inkjet Printing -- Binder Jetting 3DP -- Powder Bed Fusion: Selective Laser Sintering 3DP -- VAT Photopolymerization -- Material Extrusion: Fused Deposition Modeling 3DP -- Material Extrusion: Semi-Solid Extrusion 3DP -- Applications of 3DP for Space Pharmaceuticals -- Multifaceted Applications of 3DP in Drug Delivery Research -- Personalized Drug Dosing -- Complex Drug Release Profile -- Customized Topical Treatment Devices -- Drug Delivery Devices with Unique Dosage Forms -- Fabrication of Polypills Using 3DP Technology -- On-Demand Manufacturing -- Effects of Microgravity on Human Body and Space Pharmaceuticals -- Cardio-Circulatory: Fluid Shifts -- Muscle and Bone Loss -- Effects on the Immune System. Alterations in the Gastrointestinal System. |
| Record Nr. | UNINA-9910559394703321 |
| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Microgravity and Vision Impairments in Astronauts [[electronic resource] /] / by Erik Seedhouse
| Microgravity and Vision Impairments in Astronauts [[electronic resource] /] / by Erik Seedhouse |
| Autore | Seedhouse Erik |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (102 p.) |
| Disciplina | 616.980214 |
| Collana | SpringerBriefs in Space Development |
| Soggetto topico |
Ophthalmology
Aerospace engineering Astronautics Space sciences Aerospace Technology and Astronautics Space Sciences (including Extraterrestrial Physics, Space Exploration and Astronautics) |
| ISBN | 3-319-17870-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Syndrome-specific Anatomy and Physiology -- Earth-bound Pathophysiology of Increased Intracranial Pressure -- Pathophysiology of Increased Intracranial Pressure in Weightlessness -- Pathology, demographics and anatomy of papilledema -- Microgravity Induced Cephalad Fluid Shift -- The Role of Carbon Dioxide -- Advanced Resistive Exercise Device (ARED) -- Diet on board the International Space Station. |
| Record Nr. | UNINA-9910300165903321 |
Seedhouse Erik
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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