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Humoral Primary Immunodeficiencies / / edited by Mario Milco D'Elios, Marta Rizzi
| Humoral Primary Immunodeficiencies / / edited by Mario Milco D'Elios, Marta Rizzi |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (383 pages) |
| Disciplina | 616.979 |
| Collana | Rare Diseases of the Immune System |
| Soggetto topico |
Rheumatology
Immunology Infectious diseases Oncology Infectious Diseases Oncology |
| ISBN | 3-319-91785-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- 1. B cells and the B-cell immunological synapse.-2 Mucosal B cells -- 3 CVID. – 4 LOCID. – 5 Genetics of CVID. – 6 ICOS deficiency. – 7 CD19 deficiency -- 8 CD20 deficiency. – 9 CD21 deficiency. – 10 CD81 deficiency. - 11 TACI deficiency, . – 12 LRBA deficiency. – 13 BAFF receptor deficiency. – 14 TWEAK defects. - 15 NFKB2 deficiency. – 16 WHIM syndrome. – 17 Novel humoral PID genes. – 18 Class Switch Recombination defects, -- 19 Selective IgA deficiency -- 20 IgA with IgG subclass deficiency. - 21 Isolated IgG subclass deficiency. – 22 Thymoma with immunodeficiency. – 23 PRKC delta and PI3K-delta associated diseases. – 24 Differential diagnostic in hypogammaglobulinemia. – 25 Management of Humoral primary immunodeficiencies in pediatrics -- 26 Management of Humoral primary immunodeficiencies in adults -- 27 Vaccines in humoral PID -- 28 Humoral PID and neoplasias -- 29 Humoral PID and autoimmunity. – 30 Lung involvement -- 31 Gut involvement -- Subject Index. |
| Record Nr. | UNINA-9910337498703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunogenomics and human disease [[electronic resource] /] / [edited by] András Falus
| Immunogenomics and human disease [[electronic resource] /] / [edited by] András Falus |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley, c2006 |
| Descrizione fisica | 1 online resource (558 p.) |
| Disciplina |
616.0796
616.979 |
| Altri autori (Persone) | FalusAndrás |
| Soggetto topico | Immunogenetics |
| ISBN |
1-280-41112-0
9786610411122 0-470-03409-2 0-470-03324-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Immunogenomics and Human Disease; Contents; Preface; List of Contributors; 1 Genotyping methods and disease gene identification; 1.1 Introduction; 1.2 Genotyping of single-nucleotide polymorphisms; 1.3 Methods for interrogating SNPs; 1.4 Analysis formats; 1.5 The current generation of methods for SNP genotyping; 1.6 The next generation; 1.7 Classical HLA typing; 1.8 MHC haplotypes; 1.9 Molecular haplotyping; 1.10 Microhaplotyping; 1.11 MHC and disease associations; 1.12 Conclusions; Acknowledgements; References
2 Glycomics and the sugar code: primer to their structural basis and functionality2.1 Introduction; 2.2 Lectins as effectors in functional glycomics; 2.3 Galectins: structural principles and intrafamily diversity; 2.4 Ligand-dependent levels of affinity regulation; 2.5 Perspectives for galectin-dependent medical applications; 2.6 Conclusions; References; 3 Proteomics in clinical research: perspectives and expectations; 3.1 Introduction; 3.2 Proteomics: tools and projects; 3.3 Discussion; 3.4 Concluding remarks; Acknowledgements; References 4 Chemical genomics: bridging the gap between novel targets and small molecule drug candidates. Contribution to immunology4.1 Introduction of chemical genomics: definitions; 4.2 Chemical microarrays; 4.3 Small molecule and peptide probes for studying binding interactions through creating a covalent bond; 4.4 Photochemical proteomics; 4.5 General aspects of photoaffinity labelling; 4.6 Photoreactive probes of biomolecules; 4.7 Application to the immunobiology of living cells; 4.8 Multifunctional photoprobes for rapid analysis and screening; 4.9 Advanced application to functional proteomics 4.10 SummaryReferences; 5 Genomic and proteomic analysis of activated human monocytes; 5.1 Primary human monocytes, as a model system; 5.2 Transcriptional profiling of activated monocytes; 5.3 Functional genomics; 5.4 Proteomic analysis of activated human monocytes; References; 6 Bioinformatics as a problem of knowledge representation: applications to some aspects of immunoregulation; 6.1 Introduction; 6.2 Sequences and languages; 6.3 Three-dimensional models; 6.4 Genomes, proteomes, networks; 6.5 Computational tools; 6.6 Information processing in the immune system; 6.7 Concluding remarks References7 Immune responsiveness of human tumours; 7.1 Introduction; 7.2 Defining tumour immune responsiveness; 7.3 Studying immune responsiveness in human tumours; 7.4 Immune responsiveness in the context of therapy; 7.5 The spatial dimension in the quest for the target; 7.6 Studying the receiving end - tumour as an elusive target for immune recognition; 7.7 The role of the host in determining immune responsiveness; 7.8 Concluding remarks; References; 8 Chemokines regulate leukocyte trafficking and organ-specific metastasis; 8.1 Chemokines and chemokine receptors 8.2 Chemokine receptors in the organ-specific recruitment of tumour cells |
| Record Nr. | UNINA-9910143712203321 |
| Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunogenomics and human disease [[electronic resource] /] / [edited by] András Falus
| Immunogenomics and human disease [[electronic resource] /] / [edited by] András Falus |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley, c2006 |
| Descrizione fisica | 1 online resource (558 p.) |
| Disciplina |
616.0796
616.979 |
| Altri autori (Persone) | FalusAndrás |
| Soggetto topico | Immunogenetics |
| ISBN |
1-280-41112-0
9786610411122 0-470-03409-2 0-470-03324-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Immunogenomics and Human Disease; Contents; Preface; List of Contributors; 1 Genotyping methods and disease gene identification; 1.1 Introduction; 1.2 Genotyping of single-nucleotide polymorphisms; 1.3 Methods for interrogating SNPs; 1.4 Analysis formats; 1.5 The current generation of methods for SNP genotyping; 1.6 The next generation; 1.7 Classical HLA typing; 1.8 MHC haplotypes; 1.9 Molecular haplotyping; 1.10 Microhaplotyping; 1.11 MHC and disease associations; 1.12 Conclusions; Acknowledgements; References
2 Glycomics and the sugar code: primer to their structural basis and functionality2.1 Introduction; 2.2 Lectins as effectors in functional glycomics; 2.3 Galectins: structural principles and intrafamily diversity; 2.4 Ligand-dependent levels of affinity regulation; 2.5 Perspectives for galectin-dependent medical applications; 2.6 Conclusions; References; 3 Proteomics in clinical research: perspectives and expectations; 3.1 Introduction; 3.2 Proteomics: tools and projects; 3.3 Discussion; 3.4 Concluding remarks; Acknowledgements; References 4 Chemical genomics: bridging the gap between novel targets and small molecule drug candidates. Contribution to immunology4.1 Introduction of chemical genomics: definitions; 4.2 Chemical microarrays; 4.3 Small molecule and peptide probes for studying binding interactions through creating a covalent bond; 4.4 Photochemical proteomics; 4.5 General aspects of photoaffinity labelling; 4.6 Photoreactive probes of biomolecules; 4.7 Application to the immunobiology of living cells; 4.8 Multifunctional photoprobes for rapid analysis and screening; 4.9 Advanced application to functional proteomics 4.10 SummaryReferences; 5 Genomic and proteomic analysis of activated human monocytes; 5.1 Primary human monocytes, as a model system; 5.2 Transcriptional profiling of activated monocytes; 5.3 Functional genomics; 5.4 Proteomic analysis of activated human monocytes; References; 6 Bioinformatics as a problem of knowledge representation: applications to some aspects of immunoregulation; 6.1 Introduction; 6.2 Sequences and languages; 6.3 Three-dimensional models; 6.4 Genomes, proteomes, networks; 6.5 Computational tools; 6.6 Information processing in the immune system; 6.7 Concluding remarks References7 Immune responsiveness of human tumours; 7.1 Introduction; 7.2 Defining tumour immune responsiveness; 7.3 Studying immune responsiveness in human tumours; 7.4 Immune responsiveness in the context of therapy; 7.5 The spatial dimension in the quest for the target; 7.6 Studying the receiving end - tumour as an elusive target for immune recognition; 7.7 The role of the host in determining immune responsiveness; 7.8 Concluding remarks; References; 8 Chemokines regulate leukocyte trafficking and organ-specific metastasis; 8.1 Chemokines and chemokine receptors 8.2 Chemokine receptors in the organ-specific recruitment of tumour cells |
| Record Nr. | UNINA-9910830840803321 |
| Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Journal of the International AIDS Society
| Journal of the International AIDS Society |
| Pubbl/distr/stampa | [London], : BioMed Central |
| Disciplina | 616.979 |
| Soggetto topico |
AIDS (Disease)
HIV infections Acquired Immunodeficiency Syndrome HIV Infections AIDS & HIV |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. Zeitschrift |
| ISSN | 1758-2652 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JIAS |
| Record Nr. | UNISA-996210696403316 |
| [London], : BioMed Central | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Journal of the International AIDS Society
| Journal of the International AIDS Society |
| Pubbl/distr/stampa | [London], : BioMed Central |
| Disciplina | 616.979 |
| Soggetto topico |
AIDS (Disease)
HIV infections Acquired Immunodeficiency Syndrome HIV Infections AIDS & HIV |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. Zeitschrift |
| ISSN | 1758-2652 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JIAS |
| Record Nr. | UNINA-9910146295803321 |
| [London], : BioMed Central | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||