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Apoptosis and autoimmunity [[electronic resource] /] / edited by M. Hermann and J.R. Kalden
Apoptosis and autoimmunity [[electronic resource] /] / edited by M. Hermann and J.R. Kalden
Pubbl/distr/stampa Weinheim, : Wiley-VCH, c2003
Descrizione fisica 1 online resource (405 p.)
Disciplina 571.9/73
616.97/8
616.978
Altri autori (Persone) HerrmannM, Dr. (Martin)
KaldenJ. R (Joachim Robert)
Soggetto topico Apoptosis
Autoimmunity
Autoimmune diseases
Soggetto genere / forma Electronic books.
ISBN 1-280-52038-8
9786610520381
3-527-60529-0
3-527-60145-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Apoptosis and Autoimmunity; Preface; Contents; List of Contributors; Part 1 General Features of Apoptosis; 1 Apoptosis and Autoimmunity; 1.1 Introduction; 1.2 Autoimmune Diseases Associated with Targeted Cell Destruction; 1.2.1 What is the Mode of Cell Death?; 1.2.2 What Cells and What Effector Pathways are Responsible for Cell Death?; 1.3 Autoimmune Diseases Associated with Enhanced Cell Growth and Survival; 1.4 Autoimmune Diseases Associated with Abnormal Processing of Dying Cells; 1.5 Conclusions; 1.6 References; 2 Caspase Knockouts: Matters of Life and Death
2.1 Death, Development and Immune Function2.2 Apoptotic Pathways: from Nematode to Mammals; 2.3 Triggering a Killer: General Aspects of Caspase Activation; 2.4 Caspase-1 and -11: More than Mediators of Inflammatory Cytokines?; 2.5 Caspase-8 and the FAS Signaling Pathway; 2.6 Caspase-3: The Chief Executioner?; 2.7 Caspase-9: Mitochondrial Activation and the Apoptosome; 2.8 Caspase-2: A Duality of Function; 2.9 Caspase-12: Responding to Stress; 2.10 Compensatory Caspase Activation: A Caveat to Knockout Analysis; 2.11 Caspases: More than Simple Killers; 2.12 Concluding Remarks; 2.13 References
Part 2 Clearance of Apoptotic Cells3 Anti-inflammatory and Immunoregulatory Effects of Apoptotic Cells; 3.1 Introduction; 3.2 Anti-inflammatory Effects of Apoptotic Cells on Monocytes/Macrophages; 3.3 The Role of Anti-inflammatory Cytokines for the Inhibition of Pro-inflammatory Cytokine Production; 3.4 Monocyte/Macrophage Receptors receiving the Anti-inflammatory Signal from Apoptotic Cells; 3.5 Intracellular Signaling Events Causing the Anti-inflammatory State in Macrophages; 3.6 Apoptotic Cells Impair MHC Class II Surface Expression on Monocytes
3.7 Influence of Apoptotic Cells on DC Function in Allogeneic MLR3.8 The Presence of Apoptotic Cells can Shift the T(h) Cell Response towards T(h)2; 3.9 Apoptotic Cells Suppress Delayed-type Hypersensitivity (DTH) In Vivo; 3.10 Necrosis and Inflammation; 3.11 Implications of the Anti-inflammatory and Immunodulatory Effects of Apoptotic Cells for Health and Disease; 3.11.1 Apoptosis and Pregnancy; 3.11.2 Apoptosis and Irradiation; 3.11.3 Apoptosis and Cancer; 3.11.4 Apoptosis and Infections; 3.11.5 Apoptosis and Blood Transfusions; 3.12 References; 4 Complement and Apoptosis; 4.1 Introduction
4.2 Programmed Cell Death (PCD)4.3 Complement; 4.4 Complement and Apoptosis; 4.4.1 Role of Complement in the Execution Phase; 4.4.2 Complement Activation by Apoptotic Cells; 4.5 Apoptosis, Complement and Autoimmunity; 4.6 References; 5 Soluble Factors that Bind to Dying Cells Control the Outcome of Corpse Disposal: The Role of Pentraxins, Collectins and Autoantibodies; 5.1 Introduction; 5.2 Soluble Factors Involved in Apoptotic Cell Recognition and Internalization; 5.2.1 Corpse Clearance at Rest: Collectins; 5.2.2 Corpse Clearance at Rest: Cationic Factors and Other PS-binding Moieties
5.2.3 Corpse Clearance during Acute Inflammation: Pentraxins
Record Nr. UNINA-9910146242903321
Weinheim, : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Apoptosis and autoimmunity [[electronic resource] /] / edited by M. Hermann and J.R. Kalden
Apoptosis and autoimmunity [[electronic resource] /] / edited by M. Hermann and J.R. Kalden
Pubbl/distr/stampa Weinheim, : Wiley-VCH, c2003
Descrizione fisica 1 online resource (405 p.)
Disciplina 571.9/73
616.97/8
616.978
Altri autori (Persone) HerrmannM, Dr. (Martin)
KaldenJ. R (Joachim Robert)
Soggetto topico Apoptosis
Autoimmunity
Autoimmune diseases
ISBN 1-280-52038-8
9786610520381
3-527-60529-0
3-527-60145-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Apoptosis and Autoimmunity; Preface; Contents; List of Contributors; Part 1 General Features of Apoptosis; 1 Apoptosis and Autoimmunity; 1.1 Introduction; 1.2 Autoimmune Diseases Associated with Targeted Cell Destruction; 1.2.1 What is the Mode of Cell Death?; 1.2.2 What Cells and What Effector Pathways are Responsible for Cell Death?; 1.3 Autoimmune Diseases Associated with Enhanced Cell Growth and Survival; 1.4 Autoimmune Diseases Associated with Abnormal Processing of Dying Cells; 1.5 Conclusions; 1.6 References; 2 Caspase Knockouts: Matters of Life and Death
2.1 Death, Development and Immune Function2.2 Apoptotic Pathways: from Nematode to Mammals; 2.3 Triggering a Killer: General Aspects of Caspase Activation; 2.4 Caspase-1 and -11: More than Mediators of Inflammatory Cytokines?; 2.5 Caspase-8 and the FAS Signaling Pathway; 2.6 Caspase-3: The Chief Executioner?; 2.7 Caspase-9: Mitochondrial Activation and the Apoptosome; 2.8 Caspase-2: A Duality of Function; 2.9 Caspase-12: Responding to Stress; 2.10 Compensatory Caspase Activation: A Caveat to Knockout Analysis; 2.11 Caspases: More than Simple Killers; 2.12 Concluding Remarks; 2.13 References
Part 2 Clearance of Apoptotic Cells3 Anti-inflammatory and Immunoregulatory Effects of Apoptotic Cells; 3.1 Introduction; 3.2 Anti-inflammatory Effects of Apoptotic Cells on Monocytes/Macrophages; 3.3 The Role of Anti-inflammatory Cytokines for the Inhibition of Pro-inflammatory Cytokine Production; 3.4 Monocyte/Macrophage Receptors receiving the Anti-inflammatory Signal from Apoptotic Cells; 3.5 Intracellular Signaling Events Causing the Anti-inflammatory State in Macrophages; 3.6 Apoptotic Cells Impair MHC Class II Surface Expression on Monocytes
3.7 Influence of Apoptotic Cells on DC Function in Allogeneic MLR3.8 The Presence of Apoptotic Cells can Shift the T(h) Cell Response towards T(h)2; 3.9 Apoptotic Cells Suppress Delayed-type Hypersensitivity (DTH) In Vivo; 3.10 Necrosis and Inflammation; 3.11 Implications of the Anti-inflammatory and Immunodulatory Effects of Apoptotic Cells for Health and Disease; 3.11.1 Apoptosis and Pregnancy; 3.11.2 Apoptosis and Irradiation; 3.11.3 Apoptosis and Cancer; 3.11.4 Apoptosis and Infections; 3.11.5 Apoptosis and Blood Transfusions; 3.12 References; 4 Complement and Apoptosis; 4.1 Introduction
4.2 Programmed Cell Death (PCD)4.3 Complement; 4.4 Complement and Apoptosis; 4.4.1 Role of Complement in the Execution Phase; 4.4.2 Complement Activation by Apoptotic Cells; 4.5 Apoptosis, Complement and Autoimmunity; 4.6 References; 5 Soluble Factors that Bind to Dying Cells Control the Outcome of Corpse Disposal: The Role of Pentraxins, Collectins and Autoantibodies; 5.1 Introduction; 5.2 Soluble Factors Involved in Apoptotic Cell Recognition and Internalization; 5.2.1 Corpse Clearance at Rest: Collectins; 5.2.2 Corpse Clearance at Rest: Cationic Factors and Other PS-binding Moieties
5.2.3 Corpse Clearance during Acute Inflammation: Pentraxins
Record Nr. UNINA-9910830049703321
Weinheim, : Wiley-VCH, c2003
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Autoimmune diagnostics [[electronic resource] /] / edited by Harald Renz
Autoimmune diagnostics [[electronic resource] /] / edited by Harald Renz
Autore Renz H (Harald)
Pubbl/distr/stampa Berlin, : De Gruyter, 2012
Descrizione fisica 1 online resource (208 p.)
Disciplina 616.97/8
Altri autori (Persone) RenzH (Harald)
Soggetto topico Autoimmune diseases - Diagnosis
Autoimmunity
Soggetto non controllato Allergies
Autoimmune Diagnostics
Immune Mediated Disease
ISBN 3-11-022865-3
9786613939920
1-283-62747-7
Classificazione XG 4414
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto General aspects of autoimmune diagnostics -- Rheumatoid arthritis -- Systemic lupus erythematosus -- Consensus protocol for the detection of autoantibodies by indirect immunofluorescence technology on Hep-2 cells -- The antiphospholipid syndrome -- Inflammatory myopathies (polymyositis, dermatomyositis) -- Systemic sclerosis -- Autoimmune blistering disorders -- Autoimmune liver disease -- Autoimmunity in diabetes mellitus -- Autoimmune thyroid diseases -- Autoimmune primary adrenal insufficiency -- Inflammatory bowel disease -- Celiac disease -- Autoimmune polyendocrine syndromes.
Record Nr. UNINA-9910786471503321
Renz H (Harald)  
Berlin, : De Gruyter, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Autoimmune diagnostics / / edited by Harald Renz
Autoimmune diagnostics / / edited by Harald Renz
Autore Renz H (Harald)
Edizione [1st ed.]
Pubbl/distr/stampa Berlin, : De Gruyter, 2012
Descrizione fisica 1 online resource (208 p.)
Disciplina 616.97/8
Altri autori (Persone) RenzH (Harald)
Soggetto topico Autoimmune diseases - Diagnosis
Autoimmunity
Soggetto non controllato Allergies
Autoimmune Diagnostics
Immune Mediated Disease
ISBN 3-11-022865-3
9786613939920
1-283-62747-7
Classificazione XG 4414
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto General aspects of autoimmune diagnostics -- Rheumatoid arthritis -- Systemic lupus erythematosus -- Consensus protocol for the detection of autoantibodies by indirect immunofluorescence technology on Hep-2 cells -- The antiphospholipid syndrome -- Inflammatory myopathies (polymyositis, dermatomyositis) -- Systemic sclerosis -- Autoimmune blistering disorders -- Autoimmune liver disease -- Autoimmunity in diabetes mellitus -- Autoimmune thyroid diseases -- Autoimmune primary adrenal insufficiency -- Inflammatory bowel disease -- Celiac disease -- Autoimmune polyendocrine syndromes.
Record Nr. UNINA-9910817466403321
Renz H (Harald)  
Berlin, : De Gruyter, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Autoimmune diagnostics [[electronic resource] /] / edited by Harald Renz
Autoimmune diagnostics [[electronic resource] /] / edited by Harald Renz
Pubbl/distr/stampa Berlin, : De Gruyter, 2012
Descrizione fisica 1 online resource (208 p.)
Disciplina 616.97/8
Altri autori (Persone) RenzH (Harald)
Soggetto topico Autoimmune diseases - Diagnosis
Autoimmunity
Soggetto genere / forma Electronic books.
ISBN 3-11-022865-3
9786613939920
1-283-62747-7
Classificazione XG 4414
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto General aspects of autoimmune diagnostics -- Rheumatoid arthritis -- Systemic lupus erythematosus -- Consensus protocol for the detection of autoantibodies by indirect immunofluorescence technology on Hep-2 cells -- The antiphospholipid syndrome -- Inflammatory myopathies (polymyositis, dermatomyositis) -- Systemic sclerosis -- Autoimmune blistering disorders -- Autoimmune liver disease -- Autoimmunity in diabetes mellitus -- Autoimmune thyroid diseases -- Autoimmune primary adrenal insufficiency -- Inflammatory bowel disease -- Celiac disease -- Autoimmune polyendocrine syndromes.
Record Nr. UNINA-9910463331203321
Berlin, : De Gruyter, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Autoimmune disorders [[electronic resource] ] : symptoms, diagnosis, and treatment / / Maria E. Petrov, editor
Autoimmune disorders [[electronic resource] ] : symptoms, diagnosis, and treatment / / Maria E. Petrov, editor
Pubbl/distr/stampa New York, : Nova Science Publishers, c2011
Descrizione fisica 1 online resource (342 p.)
Disciplina 616.97/8
Altri autori (Persone) PetrovMaria E
Collana Immunology and immune system disorders
Soggetto topico Autoimmune diseases
Autoimmunity
Soggetto genere / forma Electronic books.
ISBN 1-61761-698-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Contents""; ""Preface""; ""Chapter 1 Autoimmune Liver Diseases ""; ""Chapter 2 Immunopathological Events in an Experimental Autoimmune Kidney Disease and How Those Events Can be Terminated to Regain Tolerance to Self ""; ""Chapter 3 Hematopoietic Stem Cell Transplantation for Severe Autoimmune Diseases: Time for a Reappraisal ""; ""Chapter 4 Thyroid Arterial Embolization for the Treatment of Graves� Hyperthyroidism ""; ""Chapter 5 New Targets and Approaches to Autoimmune-Induced Salivary Hypofunction""
""Chapter 6 Systemic Lupus Erythematosus: Definition, Pathogenesis and Treatment Mariana Postal""""Chapter 7 Diagnosis and Pathogenesis of Neuropsychiatric Syndromes of Systemic Lupus Erythematosus (NPSLE) ""; ""Chapter 8 Cytomegalovirus-Induced Autoimmunity""; ""Chapter 9 BehÃet's Disease: Symptoms, Diagnosis and Treatment ""; ""Chapter 10 Immunomodulators as Therapeutic Strategies for Managing Multiple Sclerosis E. W. Brenu""; ""Chapter 11 Premenstrual Syndrome: A Disease with an Autoimmune Component? Miranda A. Farage""
""Chapter 12 The Primary Target Antigenic Site in Heymann Nephritis is the Renal Proximal Convoluted Tubules� Brush Border Associated Zone of Cells """"Chapter 13 Dysregulation of Autoimmunity Caused by Silica Exposure: Fas-Mediated Apoptosis in T Lymphocytes Derived from Silicosis Patients ""; ""Chapter 14 Unusual Renal Localization of Vasculitis in Sjögren�s Syndrome: A Clinical Case Report""; ""Index""
Record Nr. UNINA-9910452873803321
New York, : Nova Science Publishers, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Autoimmune disorders [[electronic resource] ] : symptoms, diagnosis, and treatment / / Maria E. Petrov, editor
Autoimmune disorders [[electronic resource] ] : symptoms, diagnosis, and treatment / / Maria E. Petrov, editor
Pubbl/distr/stampa New York, : Nova Science Publishers, c2011
Descrizione fisica 1 online resource (342 p.)
Disciplina 616.97/8
Altri autori (Persone) PetrovMaria E
Collana Immunology and immune system disorders
Soggetto topico Autoimmune diseases
Autoimmunity
ISBN 1-61761-698-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Contents""; ""Preface""; ""Chapter 1 Autoimmune Liver Diseases ""; ""Chapter 2 Immunopathological Events in an Experimental Autoimmune Kidney Disease and How Those Events Can be Terminated to Regain Tolerance to Self ""; ""Chapter 3 Hematopoietic Stem Cell Transplantation for Severe Autoimmune Diseases: Time for a Reappraisal ""; ""Chapter 4 Thyroid Arterial Embolization for the Treatment of Graves� Hyperthyroidism ""; ""Chapter 5 New Targets and Approaches to Autoimmune-Induced Salivary Hypofunction""
""Chapter 6 Systemic Lupus Erythematosus: Definition, Pathogenesis and Treatment Mariana Postal""""Chapter 7 Diagnosis and Pathogenesis of Neuropsychiatric Syndromes of Systemic Lupus Erythematosus (NPSLE) ""; ""Chapter 8 Cytomegalovirus-Induced Autoimmunity""; ""Chapter 9 BehÃet's Disease: Symptoms, Diagnosis and Treatment ""; ""Chapter 10 Immunomodulators as Therapeutic Strategies for Managing Multiple Sclerosis E. W. Brenu""; ""Chapter 11 Premenstrual Syndrome: A Disease with an Autoimmune Component? Miranda A. Farage""
""Chapter 12 The Primary Target Antigenic Site in Heymann Nephritis is the Renal Proximal Convoluted Tubules� Brush Border Associated Zone of Cells """"Chapter 13 Dysregulation of Autoimmunity Caused by Silica Exposure: Fas-Mediated Apoptosis in T Lymphocytes Derived from Silicosis Patients ""; ""Chapter 14 Unusual Renal Localization of Vasculitis in Sjögren�s Syndrome: A Clinical Case Report""; ""Index""
Record Nr. UNINA-9910779532303321
New York, : Nova Science Publishers, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Autoimmune disorders : symptoms, diagnosis, and treatment / / Maria E. Petrov, editor
Autoimmune disorders : symptoms, diagnosis, and treatment / / Maria E. Petrov, editor
Edizione [1st ed.]
Pubbl/distr/stampa New York, : Nova Science Publishers, c2011
Descrizione fisica 1 online resource (342 p.)
Disciplina 616.97/8
Altri autori (Persone) PetrovMaria E
Collana Immunology and immune system disorders
Soggetto topico Autoimmune diseases
Autoimmunity
ISBN 1-61761-698-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""Contents""; ""Preface""; ""Chapter 1 Autoimmune Liver Diseases ""; ""Chapter 2 Immunopathological Events in an Experimental Autoimmune Kidney Disease and How Those Events Can be Terminated to Regain Tolerance to Self ""; ""Chapter 3 Hematopoietic Stem Cell Transplantation for Severe Autoimmune Diseases: Time for a Reappraisal ""; ""Chapter 4 Thyroid Arterial Embolization for the Treatment of Graves� Hyperthyroidism ""; ""Chapter 5 New Targets and Approaches to Autoimmune-Induced Salivary Hypofunction""
""Chapter 6 Systemic Lupus Erythematosus: Definition, Pathogenesis and Treatment Mariana Postal""""Chapter 7 Diagnosis and Pathogenesis of Neuropsychiatric Syndromes of Systemic Lupus Erythematosus (NPSLE) ""; ""Chapter 8 Cytomegalovirus-Induced Autoimmunity""; ""Chapter 9 BehÃet's Disease: Symptoms, Diagnosis and Treatment ""; ""Chapter 10 Immunomodulators as Therapeutic Strategies for Managing Multiple Sclerosis E. W. Brenu""; ""Chapter 11 Premenstrual Syndrome: A Disease with an Autoimmune Component? Miranda A. Farage""
""Chapter 12 The Primary Target Antigenic Site in Heymann Nephritis is the Renal Proximal Convoluted Tubules� Brush Border Associated Zone of Cells """"Chapter 13 Dysregulation of Autoimmunity Caused by Silica Exposure: Fas-Mediated Apoptosis in T Lymphocytes Derived from Silicosis Patients ""; ""Chapter 14 Unusual Renal Localization of Vasculitis in Sjögren�s Syndrome: A Clinical Case Report""; ""Index""
Record Nr. UNINA-9910820929303321
New York, : Nova Science Publishers, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The autoimmune fix : how to stop the hidden autoimmune damage that keeps you sick, fat, and tired before it turns into disease / / Tom O'Bryan ; foreword by Mark Hyman
The autoimmune fix : how to stop the hidden autoimmune damage that keeps you sick, fat, and tired before it turns into disease / / Tom O'Bryan ; foreword by Mark Hyman
Autore O'Bryan Tom
Pubbl/distr/stampa [Gordonsville, Virginia] : , : Rodale, , 2016
Descrizione fisica 1 online resource (292 pages)
Disciplina 616.97/8
Soggetto topico Autoimmune diseases
Autoimmune diseases - Treatment
ISBN 1-62336-701-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910164906203321
O'Bryan Tom  
[Gordonsville, Virginia] : , : Rodale, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genetics of autoimmunity / / [editors: Gregory Bock and Jamie Goode]
Genetics of autoimmunity / / [editors: Gregory Bock and Jamie Goode]
Pubbl/distr/stampa Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005
Descrizione fisica 1 online resource (261 p.)
Disciplina 616.97/8
Altri autori (Persone) BockGregory
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Autoimmunity
Autoimmunity - Genetic aspects
ISBN 1-280-23841-0
9786610238415
0-470-02139-X
0-470-02138-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto GENETICS OF AUTOIMMUNITY; Contents; Participants; Chair's introduction; Patterns of genetic variation in humans and mice; Discussion; Haplotype tagging in pharmacogenetics; Discussion; Multiple sclerosis: a haplotype association study; Discussion; Mapping genes for asthma and psoriasis; Discussion; Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse; Discussion; The importance of epistatic interactions in the development of autoimmunity; Discussion; Mapping autoimmune disease genes in humans: lessons from IBD and SLE; Discussion
A combined genetics and genomics approach to unravelling molecular pathways in coeliac diseaseDiscussion; Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus; Discussion; A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling; Discussion; Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity; Discussion; An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells; Discussion; Large-scale screens for cDNAs with in vivo activity; Discussion
Genomic mining of new genes and pathways in innate and adaptive immunityDiscussion; Index of contributors; Subject index
Record Nr. UNINA-9910877557303321
Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui