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Antibacterial agents / / edited by Ranjith Kumavath
| Antibacterial agents / / edited by Ranjith Kumavath |
| Pubbl/distr/stampa | Rijeka, Croatia : , : IntechOpen, , [2017] |
| Descrizione fisica | 1 online resource (127 pages) : illustrations |
| Disciplina | 616.92061 |
| Soggetto topico | Antibacterial agents |
| ISBN |
953-51-4817-6
953-51-3200-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910251431003321 |
| Rijeka, Croatia : , : IntechOpen, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antibacterials : Volume I / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
| Antibacterials : Volume I / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (203 pages) |
| Disciplina | 616.92061 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Biochemistry Organic chemistry Medicinal Chemistry Biochemistry, general Organic Chemistry |
| ISBN | 3-319-68097-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antibacterial New Target Discovery: Sentinel Examples, Strategies, and Surveying Success -- The Antibiotic Future -- Synergistic Antibiotic Combinations -- Antibiotic Adjuvants -- Allosteric Inhibition of Bacterial Targets: An Opportunity for Discovery of Novel Antibacterial Classes -- Four Ways to Skin a Cat: Inhibition of Bacterial Topoisomerases Leading to the Clinic -- The Clinical Development of Antibacterial Drugs: A Guide for the Discovery Scientist. |
| Record Nr. | UNINA-9910298598303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antibacterials : Volume II / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
| Antibacterials : Volume II / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (222 pages) : illustrations |
| Disciplina | 616.92061 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Biochemistry Organic chemistry Medicinal Chemistry Biochemistry, general Organic Chemistry |
| ISBN | 3-319-70839-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Nucleoside Natural Product Antibiotics Targetting Microbial Cell Wall Biosynthesis -- The Cyclic Lipopeptide Antibiotics -- Fully Synthetic Tetracyclines: Increasing Chemical Diversity to Combat Multidrug-Resistant Bacterial Infections -- The Antifolates -- The Oxazolidinones.- Sideromycins as Pathogen-Targeted Antibiotics -- Quorum Sensing Inhibitors as Pathoblockers for Pseudomonas aeruginosa Infections: A New Concept in Anti-Infective Drug Discovery. |
| Record Nr. | UNINA-9910298596403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The antibiotic era : reform, resistance, and the pursuit of a rational therapeutics / / Scott H. Podolsky
| The antibiotic era : reform, resistance, and the pursuit of a rational therapeutics / / Scott H. Podolsky |
| Autore | Podolsky Scott H. |
| Pubbl/distr/stampa | Baltimore, Maryland : , : Johns Hopkins University Press, , 2015 |
| Descrizione fisica | 1 online resource (324 p.) |
| Disciplina | 616.92061 |
| Soggetto topico |
Antibacterial agents - United States - History
Pharmaceutical industry - United States |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-4214-1594-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Setting the stage : the origins of antibiotic reform -- Antibiotics and the invocation of the controlled clinical trial -- From sigmamycin to panalba : antibiotics and the FDA -- The limits to delimitation -- Responding to antibiotic resistance. |
| Record Nr. | UNINA-9910459724203321 |
Podolsky Scott H.
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| Baltimore, Maryland : , : Johns Hopkins University Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The antibiotic era : reform, resistance, and the pursuit of a rational therapeutics / / Scott H. Podolsky
| The antibiotic era : reform, resistance, and the pursuit of a rational therapeutics / / Scott H. Podolsky |
| Autore | Podolsky Scott H. |
| Pubbl/distr/stampa | Baltimore, Maryland : , : Johns Hopkins University Press, , 2015 |
| Descrizione fisica | 1 online resource (324 p.) |
| Disciplina | 616.92061 |
| Soggetto topico |
Antibacterial agents - United States - History
Pharmaceutical industry - United States |
| ISBN | 1-4214-1594-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Setting the stage : the origins of antibiotic reform -- Antibiotics and the invocation of the controlled clinical trial -- From sigmamycin to panalba : antibiotics and the FDA -- The limits to delimitation -- Responding to antibiotic resistance. |
| Record Nr. | UNINA-9910787232703321 |
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Podolsky Scott H.
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| Baltimore, Maryland : , : Johns Hopkins University Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The antibiotic era : reform, resistance, and the pursuit of a rational therapeutics / / Scott H. Podolsky
| The antibiotic era : reform, resistance, and the pursuit of a rational therapeutics / / Scott H. Podolsky |
| Autore | Podolsky Scott H. |
| Pubbl/distr/stampa | Baltimore, Maryland : , : Johns Hopkins University Press, , 2015 |
| Descrizione fisica | 1 online resource (324 p.) |
| Disciplina | 616.92061 |
| Soggetto topico |
Antibacterial agents - United States - History
Pharmaceutical industry - United States |
| ISBN | 1-4214-1594-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Setting the stage : the origins of antibiotic reform -- Antibiotics and the invocation of the controlled clinical trial -- From sigmamycin to panalba : antibiotics and the FDA -- The limits to delimitation -- Responding to antibiotic resistance. |
| Record Nr. | UNINA-9910812813903321 |
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Podolsky Scott H.
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| Baltimore, Maryland : , : Johns Hopkins University Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacteria versus Antibacterial Agents : an integrated approach / / Oreste A. Mascaretti
| Bacteria versus Antibacterial Agents : an integrated approach / / Oreste A. Mascaretti |
| Autore | Mascaretti Oreste A. |
| Pubbl/distr/stampa | Washington, D.C. : , : John Wiley & Sons, Inc., , 2014 |
| Descrizione fisica | 1 online resource (xx, 393 pages) |
| Disciplina | 616.92061 |
| Soggetto topico | Antibacterial agents |
| ISBN | 1-68367-218-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830725103321 |
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Mascaretti Oreste A.
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| Washington, D.C. : , : John Wiley & Sons, Inc., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multiple action-based design approaches to antibacterials / / John Bremner
| Multiple action-based design approaches to antibacterials / / John Bremner |
| Autore | Bremner John |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (xiii, 193 pages) : illustrations |
| Disciplina | 616.92061 |
| Soggetto topico | Antibacterial agents |
| ISBN | 981-16-0999-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- About the Author -- 1 Antibacterials -- 1.1 Bacteria -- 1.2 Antibacterial Action -- 1.3 Bacterial Resistance to Antibacterials -- 1.3.1 Introduction to Key Resistance Mechanisms -- 1.3.2 Resistance and Resilience -- 1.3.3 The Gram-Negative Challenge -- 1.3.4 Other Survival Strategies -- 1.4 Approaches to Meeting Needs -- 1.5 Ways to Achieve Multi-action Effects -- 1.6 Bacterial Over Host Selectivity -- References -- 2 Antibacterial Combinations -- 2.1 Introduction -- 2.1.1 Dual Combinations Resulting in Two Actions -- 2.1.2 Dual Combinations Resulting in Three or More Actions -- 2.1.3 Triple Combinations Resulting in Three or More Actions -- 2.1.4 Quadruple Combinations with Four or More Actions -- 2.1.5 Pentuple Combinations -- 2.2 Summary -- References -- 3 Single Molecule Non-cleavable Multiply Active Antibacterials -- 3.1 Introduction to General Design Considerations -- 3.1.1 General Approaches to Hybrids -- 3.1.2 Factors in Antibacterial Hybrid Design -- 3.2 Designing for Mainly Dual Activity -- 3.2.1 Dual Action Antibacterial Hybrids -- 3.2.2 Examples of Dual Action Agents from Nature -- 3.2.3 Berberine as a Starting Point for Design -- 3.3 Triple Action Antibacterial Hybrid Agents -- 3.3.1 General Points -- 3.3.2 Potential Design Based on Pharmacophoric Elements -- 3.3.3 Established and Potential Single Molecule Triple Action or Interaction Agents -- 3.3.4 Designing Potential New Non-cleavable Triple Action Agents -- 3.4 More Than Triple Action Hybrid Agents -- References -- 4 Design Principles and Development of Prodrugs for Multiply Active Antibacterials -- 4.1 Definitions -- 4.1.1 Carrier-Linked Prodrugs (Carrier Prodrugs) -- 4.1.2 Bioprecursor Prodrugs -- 4.2 Introduction to Prodrugs for Triple or Higher Action Antibacterials -- 4.2.1 Design Considerations.
4.2.2 Classification and Examples of Cleavable Types for Triple or Higher Action -- 4.2.3 Cleavable Type I -- 4.2.4 Cleavable Type II -- 4.2.5 Cleavable Type III -- 4.2.6 Cleavable Type IV -- 4.3 Release Mechanisms and Prodrug Design -- 4.3.1 Biological -- 4.3.2 Chemical -- 4.3.3 Physical -- 4.4 Metabolism Activated Multi-targeting -- 4.5 Conclusion -- References -- 5 Future Possibilities -- 5.1 Introduction -- 5.2 New Combinations and Single Molecules with Multi-activity Development Potential -- 5.2.1 Combinations -- 5.2.2 Hybrid Molecule Possibibilities -- 5.3 Search for Different Chemical Structure Types -- 5.3.1 In Silico Advances -- 5.4 New Modes of Action/New Targets -- 5.5 DNA and RNA Level Modulation -- 5.6 Proteins and Antibacterials -- 5.7 Concluding Remarks -- References -- Index. |
| Record Nr. | UNINA-9910484000003321 |
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Bremner John
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| Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Antibacterial Agents / / Fiorella Meneghetti and Daniela Barlocco
| Novel Antibacterial Agents / / Fiorella Meneghetti and Daniela Barlocco |
| Autore | Meneghetti Fiorella |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022 |
| Descrizione fisica | 1 online resource (410 pages) : illustrations |
| Disciplina | 616.92061 |
| Soggetto topico | Antibacterial agents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674033403321 |
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Meneghetti Fiorella
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| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antimicrobial Nanodrugs / / Fu-Gen Wu, editor
| Recent Advances in Antimicrobial Nanodrugs / / Fu-Gen Wu, editor |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 |
| Descrizione fisica | 1 online resource (206 pages) |
| Disciplina | 616.92061 |
| Soggetto topico | Antibacterial agents |
| ISBN | 3-0365-7228-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910719775103321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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