Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910457252903321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910784598503321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in antiviral drug design . Volume 5 / / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 / / editor, E. De Clercq |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910821703003321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||