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Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910457252903321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq
| Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
| Pubbl/distr/stampa | Greenwich, CT ; ; London, England, : Jai Press, 2007 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
616.9
616.9/25061/05 616.91061 |
| Altri autori (Persone) | De ClercqErik |
| Collana | Advances in antiviral drug design |
| Soggetto topico |
Antiviral agents
Anti-infective agents |
| ISBN |
1-281-11983-0
9786611119836 0-08-054824-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
| Record Nr. | UNINA-9910784598503321 |
| Greenwich, CT ; ; London, England, : Jai Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Viral Drug Delivery Systems : Advances in Treatment of Infectious Diseases / / edited by Ranjita Shegokar, Yashwant Pathak
| Viral Drug Delivery Systems : Advances in Treatment of Infectious Diseases / / edited by Ranjita Shegokar, Yashwant Pathak |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (X, 409 p. 53 illus., 47 illus. in color.) |
| Disciplina |
615.6
616.91061 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical chemistry Diseases Pharmacology Epidemiology Pharmacy Drug Delivery Pharmaceutics |
| ISBN | 3-031-20537-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Global health and Viral diseases past, present and Future -- Drug resistance and statistics and patent status -- cellular understanding viral diseases -- Viral: current treatment options -- Mucosal drug delivery strategies for antiviral intervention -- Micro, nano emulsions in viral -- Novel formulation approaches to treat Ebola- virus -- Ebola- drug delivery -- Polymers for Bio sensing Applications in antiviral therapy and diagnosis -- Nanotechnology: A Stepping Stone towards Viral Hepatitis Treatment and Prevention in Children -- Recent Developments in the Treatment of Influenza -- Covid 19: from molecular pathogenesis to potential repurposed treatments -- Nano drug delivery systems for Covid-19-drug delivery -- Exploring the link between malaria and Covid 19 -- Characterization of biofunctionalized nanoparticles in ID -- Covid- azithromycin-ritonavir -- Strategies to combat Covid-19 drug delivery -- Phytomolecules and NDDS Covid-19. |
| Record Nr. | UNINA-9910686478003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||