Cyclin dependent kinase 5 (Cdk5) [[electronic resource] /] / Nancy Y. Ip, Li-Huei Tsai, editors |
Edizione | [1st ed. 2008.] |
Pubbl/distr/stampa | New York ; ; London, : Springer, c2008 |
Descrizione fisica | 1 online resource (325 p.) |
Disciplina | 616.80471 |
Altri autori (Persone) |
IpNancy Yuk-Yu
TsaiLi-Huei |
Soggetto topico |
Cyclin-dependent kinases - Inhibitors - Therapeutic use
Cyclin-dependent kinases Nervous system - Degeneration - Etiology Nervous system - Degeneration - Treatment |
Soggetto genere / forma | Electronic books. |
ISBN |
1-282-03782-X
9786612037825 0-387-78887-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cdk5/p35 Regulates Neuronal Migration -- CRMP Family Protein: Novel Targets for Cdk5 That Regulates Axon Guidance, Synapse Maturation, and Cell Migration -- Cdk5 in Presynapses -- Cyclin-Dependent Kinase 5: A Critical Regulator of Neurotransmitter Release -- Cdk5 in Dendrite and Synapse Development: Emerging Role as a Modulator of Receptor Tyrosine Kinase Signaling -- Cyclin-Dependent Kinase 5 (Cdk5) Modulates Signal Transduction Pathways Regulating Neuronal Survival -- CDK5 and Mitochondrial Cell Death Pathways -- Regulation and Function of Cdk5 in the Nucleus -- Cdk5 May Be an Atypical Kinase, but Not in the Way You Think -- Cdk5 and Neuregulin-1 Signaling -- Cyclin-Dependent Kinase 5 and Insulin Secretion -- Protein–Protein Interactions Involving the N-Terminus of p35 -- The Kinase Activity of Cdk5 and Its Regulation -- The Structural Bases of CDK5 Activity -- Cdk5, a Journey from Brain to Pain: Lessons from Gene Targeting -- Involvement of Cdk5 in Synaptic Plasticity, and Learning and Memory -- Cyclin-Dependent Kinase 5 (Cdk5): Linking Synaptic Plasticity and Neurodegeneration -- Cdk5 as a Drug Target for Alzheimer’s Disease. |
Record Nr. | UNINA-9910454619303321 |
New York ; ; London, : Springer, c2008 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cyclin dependent kinase 5 (Cdk5) [[electronic resource] /] / Nancy Y. Ip, Li-Huei Tsai, editors |
Edizione | [1st ed. 2008.] |
Pubbl/distr/stampa | New York ; ; London, : Springer, c2008 |
Descrizione fisica | 1 online resource (325 p.) |
Disciplina | 616.80471 |
Altri autori (Persone) |
IpNancy Yuk-Yu
TsaiLi-Huei |
Soggetto topico |
Cyclin-dependent kinases - Inhibitors - Therapeutic use
Cyclin-dependent kinases Nervous system - Degeneration - Etiology Nervous system - Degeneration - Treatment |
ISBN |
1-282-03782-X
9786612037825 0-387-78887-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cdk5/p35 Regulates Neuronal Migration -- CRMP Family Protein: Novel Targets for Cdk5 That Regulates Axon Guidance, Synapse Maturation, and Cell Migration -- Cdk5 in Presynapses -- Cyclin-Dependent Kinase 5: A Critical Regulator of Neurotransmitter Release -- Cdk5 in Dendrite and Synapse Development: Emerging Role as a Modulator of Receptor Tyrosine Kinase Signaling -- Cyclin-Dependent Kinase 5 (Cdk5) Modulates Signal Transduction Pathways Regulating Neuronal Survival -- CDK5 and Mitochondrial Cell Death Pathways -- Regulation and Function of Cdk5 in the Nucleus -- Cdk5 May Be an Atypical Kinase, but Not in the Way You Think -- Cdk5 and Neuregulin-1 Signaling -- Cyclin-Dependent Kinase 5 and Insulin Secretion -- Protein–Protein Interactions Involving the N-Terminus of p35 -- The Kinase Activity of Cdk5 and Its Regulation -- The Structural Bases of CDK5 Activity -- Cdk5, a Journey from Brain to Pain: Lessons from Gene Targeting -- Involvement of Cdk5 in Synaptic Plasticity, and Learning and Memory -- Cyclin-Dependent Kinase 5 (Cdk5): Linking Synaptic Plasticity and Neurodegeneration -- Cdk5 as a Drug Target for Alzheimer’s Disease. |
Record Nr. | UNINA-9910782704403321 |
New York ; ; London, : Springer, c2008 | ||
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Lo trovi qui: Univ. Federico II | ||
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Developmental neurotoxicology research [[electronic resource] ] : principles, models, techniques, strategies, and mechanisms / / [edited by] Cheng Wang, William Slikker Jr |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2011 |
Descrizione fisica | 1 online resource (666 p.) |
Disciplina |
616.8/0471
616.80471 |
Altri autori (Persone) |
WangCheng <1954->
SlikkerWilliam |
Soggetto topico |
Neurotoxicology
Developmental toxicology |
ISBN |
0-470-92274-5
1-282-90483-3 9786612904837 0-470-91705-9 0-470-91706-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
DEVELOPMENTALNEUROTOXICOLOGYRESEARCH; CONTENTS; PREFACE; CONTRIBUTORS; I MODELS, APPROACHES, AND CHALLENGES IN NEUROTOXICITY RESEARCH DURING DEVELOPMENT; 1 APPROACHES AND MODELS FOR EVALUATING THE TOXIC EFFECTS OF ANESTHETICS IN THE DEVELOPING NERVOUS SYSTEM; 2 SYSTEMS BIOLOGY APPROACHES TO NEUROTOXICITY STUDIES DURING DEVELOPMENT; 3 BEHAVIORAL APPROACHES FOR ASSESSING NERVOUS SYSTEM FUNCTION DURING DEVELOPMENT IN ANIMAL MODELS; 4 APPLICATIONS OF UNBIASED STEREOLOGY TO NEURODEVELOPMENTAL TOXICOLOGY; II EFFECTS OF ANESTHETICS AND THEIR POTENTIAL NEUROTOXICITY DURING DEVELOPMENT
5 NEUROTOXIC EFFECTS OF ANESTHETICS AND POTENTIAL PROTECTIVE AGENTS6 PERINATAL RHESUS MONKEY MODELS AND ANESTHETIC-INDUCED NEURONAL CELL DEATH; 7 EFFECTS OF GASEOUS ANESTHETIC COMBINATIONS DURING DEVELOPMENT; 8 PERINATAL ANESTHETIC ADMINISTRATION AND SHORT LONG-TERM BEHAVIORAL DEFICITS; III THE DEVELOPMENTAL BASIS OF ADOLESCENT OR ADULT DISEASE; 9 DEVELOPMENTAL LEAD EXPOSURE, EPIGENTICS AND LATE ONSET ALZHEIMER'S DISEASE; 10 DEVELOPMENTAL TRAJECTORIES OF AUTISM AND ENVIRONMENTAL EXPOSURES-WHAT WE KNOW AND WHERE WE NEED TO GO; 11 ACTIONS OF MANGANESE ON PUBERTAL DEVELOPMENT 12 EXPOSURE OF THE DEVELOPING BRAIN TO POLYCHLORINATED BIPHENYLS INFLUENCES THE SUSCEPTIBILITY OF THE ADULT BRAIN TO STRESS13 A NEURODEVELOPMENTAL ORIGIN FOR PAKINSON'S DISEASE: A LINK TO THE FETAL BASIS FOR ADULT DISEASE HYPOTHESIS; 14 GENETIC AND ENVIRONMENTAL FACTORS IN ATTENTION-DEFICIT HYPERACTIVITY DISORDER; IV RISK ASSESSMENT OF METHYL MERCURY AND ITS EFFECTS ON NEURODEVELOPMENT; 15 FISH NUTRIENTS AND METHYLMERCURY: A VIEW FROM THE LABORATORY 16 NEURODEVELOPMENTAL EFFECTS OF MATERNAL NUTRITION STATUS AND EXPOSURE TO METHYL MERCURY FROM EATING FISH DURING PREGNANCY: EVIDENCE FROM THE SEYCHELLES CHILD DEVELOPMENT STUDY17 METHYLMERCURY NEUROTOXICOLOGY: FROM RARE POISONINGS TO SILENT PANDEMIC; 18 OXIDATIVE STRESS AND METHYLMERCURY-INDUCED NEUROTOXICITY; 19 LEARNING DEFICITS AND DEPRESSION-LIKE BEHAVIORS ASSOCIATED WITH DEVELOPMENTAL METHYLMERCURY EXPOSURES; 20 METHYLMERCURY EFFECTS ON NEURAL DEVELOPMENTAL SIGNALING PATHWAYS; V AUTISM SPECTRUM DISORDERS; 21 NEURODEVELOPMENTAL TOXICOLOGY AND AUTISM SPECTRUM DISORDERS 22 REDOX IMBALANCE AND THE METABOLIC PATHOLOGY OF AUTISM23 NEUROINFLAMMATION AND AUTISM; 24 AUTISM, PERIPHERAL IMMUNITY, AND POLYBROMINATED DIPHENYL ETHERS; 25 AN EMERGING GENE-ENVIRONMENT INTERACTION MODEL: AUTISM SPECTRUM DISORDER PHENOTYPES RESULTING FROM EXPOSURE TO ENVIRONMENTAL CONTAMINANTS DURING GESTATION; VI STRATEGIES AND PROGRESS IN EPILEPSY RESEARCH; 26 NEONATAL SEIZURES; 27 EXPERIMENTAL MODELS OF EPILEPTOGENESIS; 28 EFFECT OF SEIZURES ON THE DEVELOPING BRAIN: LESSONS FROM THE LABORATORY; INDEX |
Record Nr. | UNINA-9910133587803321 |
Hoboken, N.J., : Wiley, c2011 | ||
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Lo trovi qui: Univ. Federico II | ||
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Developmental neurotoxicology research [[electronic resource] ] : principles, models, techniques, strategies, and mechanisms / / [edited by] Cheng Wang, William Slikker Jr |
Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2011 |
Descrizione fisica | 1 online resource (666 p.) |
Disciplina |
616.8/0471
616.80471 |
Altri autori (Persone) |
WangCheng <1954->
SlikkerWilliam |
Soggetto topico |
Neurotoxicology
Developmental toxicology |
ISBN |
0-470-92274-5
1-282-90483-3 9786612904837 0-470-91705-9 0-470-91706-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
DEVELOPMENTALNEUROTOXICOLOGYRESEARCH; CONTENTS; PREFACE; CONTRIBUTORS; I MODELS, APPROACHES, AND CHALLENGES IN NEUROTOXICITY RESEARCH DURING DEVELOPMENT; 1 APPROACHES AND MODELS FOR EVALUATING THE TOXIC EFFECTS OF ANESTHETICS IN THE DEVELOPING NERVOUS SYSTEM; 2 SYSTEMS BIOLOGY APPROACHES TO NEUROTOXICITY STUDIES DURING DEVELOPMENT; 3 BEHAVIORAL APPROACHES FOR ASSESSING NERVOUS SYSTEM FUNCTION DURING DEVELOPMENT IN ANIMAL MODELS; 4 APPLICATIONS OF UNBIASED STEREOLOGY TO NEURODEVELOPMENTAL TOXICOLOGY; II EFFECTS OF ANESTHETICS AND THEIR POTENTIAL NEUROTOXICITY DURING DEVELOPMENT
5 NEUROTOXIC EFFECTS OF ANESTHETICS AND POTENTIAL PROTECTIVE AGENTS6 PERINATAL RHESUS MONKEY MODELS AND ANESTHETIC-INDUCED NEURONAL CELL DEATH; 7 EFFECTS OF GASEOUS ANESTHETIC COMBINATIONS DURING DEVELOPMENT; 8 PERINATAL ANESTHETIC ADMINISTRATION AND SHORT LONG-TERM BEHAVIORAL DEFICITS; III THE DEVELOPMENTAL BASIS OF ADOLESCENT OR ADULT DISEASE; 9 DEVELOPMENTAL LEAD EXPOSURE, EPIGENTICS AND LATE ONSET ALZHEIMER'S DISEASE; 10 DEVELOPMENTAL TRAJECTORIES OF AUTISM AND ENVIRONMENTAL EXPOSURES-WHAT WE KNOW AND WHERE WE NEED TO GO; 11 ACTIONS OF MANGANESE ON PUBERTAL DEVELOPMENT 12 EXPOSURE OF THE DEVELOPING BRAIN TO POLYCHLORINATED BIPHENYLS INFLUENCES THE SUSCEPTIBILITY OF THE ADULT BRAIN TO STRESS13 A NEURODEVELOPMENTAL ORIGIN FOR PAKINSON'S DISEASE: A LINK TO THE FETAL BASIS FOR ADULT DISEASE HYPOTHESIS; 14 GENETIC AND ENVIRONMENTAL FACTORS IN ATTENTION-DEFICIT HYPERACTIVITY DISORDER; IV RISK ASSESSMENT OF METHYL MERCURY AND ITS EFFECTS ON NEURODEVELOPMENT; 15 FISH NUTRIENTS AND METHYLMERCURY: A VIEW FROM THE LABORATORY 16 NEURODEVELOPMENTAL EFFECTS OF MATERNAL NUTRITION STATUS AND EXPOSURE TO METHYL MERCURY FROM EATING FISH DURING PREGNANCY: EVIDENCE FROM THE SEYCHELLES CHILD DEVELOPMENT STUDY17 METHYLMERCURY NEUROTOXICOLOGY: FROM RARE POISONINGS TO SILENT PANDEMIC; 18 OXIDATIVE STRESS AND METHYLMERCURY-INDUCED NEUROTOXICITY; 19 LEARNING DEFICITS AND DEPRESSION-LIKE BEHAVIORS ASSOCIATED WITH DEVELOPMENTAL METHYLMERCURY EXPOSURES; 20 METHYLMERCURY EFFECTS ON NEURAL DEVELOPMENTAL SIGNALING PATHWAYS; V AUTISM SPECTRUM DISORDERS; 21 NEURODEVELOPMENTAL TOXICOLOGY AND AUTISM SPECTRUM DISORDERS 22 REDOX IMBALANCE AND THE METABOLIC PATHOLOGY OF AUTISM23 NEUROINFLAMMATION AND AUTISM; 24 AUTISM, PERIPHERAL IMMUNITY, AND POLYBROMINATED DIPHENYL ETHERS; 25 AN EMERGING GENE-ENVIRONMENT INTERACTION MODEL: AUTISM SPECTRUM DISORDER PHENOTYPES RESULTING FROM EXPOSURE TO ENVIRONMENTAL CONTAMINANTS DURING GESTATION; VI STRATEGIES AND PROGRESS IN EPILEPSY RESEARCH; 26 NEONATAL SEIZURES; 27 EXPERIMENTAL MODELS OF EPILEPTOGENESIS; 28 EFFECT OF SEIZURES ON THE DEVELOPING BRAIN: LESSONS FROM THE LABORATORY; INDEX |
Record Nr. | UNINA-9910830131203321 |
Hoboken, N.J., : Wiley, c2011 | ||
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Lo trovi qui: Univ. Federico II | ||
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Drug-induced neurological disorders / / Kewal K. Jain |
Autore | Jain K. K (Kewal K.) |
Edizione | [Fourth edition.] |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (608 pages) |
Disciplina | 616.80471 |
Soggetto topico |
Nervous system - Diseases - Etiology
Psicopatologia Malalties del sistema nerviós Efectes secundaris dels medicaments |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-73503-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910492145503321 |
Jain K. K (Kewal K.)
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Cham, Switzerland : , : Springer, , [2021] | ||
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Lo trovi qui: Univ. Federico II | ||
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Fungal Infections of the Central Nervous System : Pathogens, Diagnosis, and Management / / edited by Mehmet Turgut, Sundaram Challa, Ali Akhaddar |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (479 pages) |
Disciplina | 616.80471 |
Soggetto topico |
Neurosurgery
Neurology Neuroradiology Pathology Infectious diseases Otorhinolaryngology Neurology Infectious Diseases |
ISBN | 3-030-06088-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | PREFACE -- INTRODUCTION -- SECTION I: GENERAL CONSIDERATIONS -- Historical aspects of fungal infections -- Epidemiology of fungal infections -- Morphological classification of fungal infections (yeasts, molds, dimorphic) -- Pathogenesis of fungal infections -- Predisposing factors -- Histopathology -- Molecular genetics and genomics of fungal infections -- SECTION II: FUNGAL PATHOGENS: PATHOGENESIS, PATHOLOGY AND DIAGNOSIS -- Chapter 8: Aspergillosis -- Candidiasis -- Mucormycosis -- Histoplasmosis and coccidioidomycosis -- Cryptococcosis -- Blastomycosis and phaeohyphomycosis -- Onychomycosis -- epeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">Emmonsiosis -- Cladophialophora bantiana -- Cladosporidium, Fusarium spp, Bipolaris hawaiiensis, Schizophyllum commune, Mycoplasma hominis, Scedosporium apiospermum -- SECTION III: CLINICAL SYNDROMES OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS -- Meningitis and meningo-encephalitis -- Raised intracranial pressure -- Hydrocephalus -- Intracranial space occupying lesions -- Skull-base syndromes -- Orbito-rhino-cerebral syndrome -- Cavernous sinus syndrome -- Intracranial fungal aneurysms -- Acute ischemic or hemorrhagic stroke syndromes -- Spinal syndromes -- SECTION III: RADIOLOGICAL FINDINGS OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS -- Magnetic resonance imaging -- Positron emission tomography-computed tomography -- Imaging findings of fungal infections of the cranial and peripheral nerves -- Imaging findings of fungal infections of sinuses extending into brain -- Imaging findings of fungal infections of spine and spinal cord -- SECTION IV: THERAPY OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS -- Antifungals: from genomics to resistance and the development of novel agents -- Surgical therapy -- Prognosis of fungal infections involving the central nervous system and its coverings -- SECTION VI: FURTHER INSIGHTS INTO FUNGAL INFECTIONS -- In vitro and animal models of fungal infections oReal-time PCR: advanced technologies and applications -- Next-generation sequencing: current technologies and applications -- Current innovations and future trends -- CONCLUSIONS. |
Record Nr. | UNINA-9910349363403321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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GeNeDis 2020 : Genetics and Neurodegenerative Diseases / / edited by Panayiotis Vlamos |
Edizione | [1st ed. 2021.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
Descrizione fisica | 1 online resource (421 pages) |
Disciplina |
616.80471
618.97 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Neurosciences
Medical genetics Bioinformatics Neuroscience Medical Genetics Computational and Systems Biology Malalties neurodegeneratives |
Soggetto genere / forma |
Congressos
Llibres electrònics |
ISBN |
9783030787875
9783030787868 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1-Attitudes and smoking prevalence among undergraduate students in central Greece -- 2-Care of patients with Alzheimer’s disease -- 3-Regulation of antioxidant enzymes levels in rat brain -- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy -- 5-Cerebral critical closing pressure at concomitant traumatic brain injury -- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias -- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates -- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases -- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma -- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study -- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients -- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial -- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents -- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study -- 15-Kisspeptin and the genetic obesity interactome -- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis -- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia -- 18-Ebola virus disease and current therapeutic strategies; A review -- 19-Hyperbaric Oxygen Therapy effect on “Kinesia Paradoxa” Brain Circuits -- 20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line -- 21-Phospholipid Fatty Acid Profile of Spirulina platensis -- 22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study -- 23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives -- 24-Force spectroscopy in mechanical protein domains unfolding -- 25-Investigating the genetic component of Parkinson’s Disease -- 26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition -- 27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases -- 28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students -- 29-Synthesis, in silico stuiesand biological evaluation of 1, 3 ,4 oxadiazino indole derivatives -- 30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies -- 31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy -- 32-Microbes and the games they play -- 33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy -- 34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study -- 35-The effect of nutrients on Alzheimer’s disease biomarkers: A metabolomic approach -- 36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease -- 37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases -- 38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1 -- 39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome -- 40-Clinical and molecular study of common thrombophilia mutation prothrombin G20210A -- 41-Prenatal genetic testing for X-linked hypohidrotic ectodermal dysplasia -- 42-Preimplantation genetic testing for spastic paraplegia type 3 -- 43-Synthesis, anti-inflammatory activity and in-silico studies of some new 3-({P-DIMETHYLAMINO}BENZYLIDENE YDRAZINYLIDENE)-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES -- 44-Design, characterization and docking studies of some novel isatin derivatives for anticonvulsant and antidepressant activity -- 45-Skin mirrors Brain: A Chance for Alzheimer’s Disease Research -- 46-Mitochondrial homeostasis in neurodegeneration and ageing -- 47-The Alzheimer's Disease Chronicles: will evidence triumph over adversity? -- 48-Liposomes: Production Methods and Application in Alzheimer’s Disease -- 49-Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision -- 50-Biomarkers and Precision Medicine in Alzheimer’s Disease -- 51-The role of microRNAs in thrombosis -- 52-Photo-oxygenation: an innovative new therapeutic approach against amyloidoses. |
Record Nr. | UNINA-9910520073303321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta |
Pubbl/distr/stampa | New Jersey, : World Scientific, c2003 |
Descrizione fisica | 1 online resource (538 p.) |
Disciplina | 616.80471 |
Altri autori (Persone) | ZattaPaolo |
Soggetto topico |
Metal ions - Physiological effect
Molecular neurobiology Nervous system - Degeneration Neurotoxicology |
Soggetto genere / forma | Electronic books. |
ISBN |
1-281-95608-2
9786611956080 981-279-669-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION 2. ANATOMY OF THE OLFACTORY SYSTEM |
Record Nr. | UNINA-9910454078003321 |
New Jersey, : World Scientific, c2003 | ||
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Lo trovi qui: Univ. Federico II | ||
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Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta |
Pubbl/distr/stampa | New Jersey, : World Scientific, c2003 |
Descrizione fisica | 1 online resource (538 p.) |
Disciplina | 616.80471 |
Altri autori (Persone) | ZattaPaolo |
Soggetto topico |
Metal ions - Physiological effect
Molecular neurobiology Nervous system - Degeneration Neurotoxicology |
ISBN |
1-281-95608-2
9786611956080 981-279-669-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION 2. ANATOMY OF THE OLFACTORY SYSTEM |
Record Nr. | UNINA-9910782283203321 |
New Jersey, : World Scientific, c2003 | ||
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Lo trovi qui: Univ. Federico II | ||
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Microglia : Physiology, Pathophysiology and Therapeutic Potential / / edited by Marie-Ève Tremblay, Alexei Verkhratsky |
Autore | Tremblay Marie-Ève |
Edizione | [1st ed. 2024.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024 |
Descrizione fisica | 1 online resource (635 pages) |
Disciplina | 616.80471 |
Altri autori (Persone) | VerkhratskyAlexei |
Collana | Advances in Neurobiology |
Soggetto topico |
Neurosciences
Neurology Immunology Neuroscience |
ISBN | 3-031-55529-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | PART I: Introduction -- Chapter 1: General Pathophysiology of Microglia -- Chapter 2: History of Microglia -- Chapter 3: Evolution of Microglia -- Chapter 4: Visualization, Fate Mapping, Ablation and Mutagenesis of Microglia in the Mouse Brain -- Chapter 5: Technological Innovations: Progress of the Structural and Functional in vivo Imaging of Microglia -- PART II: Basic Discoveries in Physiology -- Chapter 6:Microglial Physiology: Receptors -- Chapter 7: Microglial Physiology: Calcium Signalling -- Chapter 8:Contactomics of Microglia and Intercellular Communication -- Chapter 9: Elimination of Neurones: Embryonic and Postnatal Development -- Chapter 10: Developmental Angiogenesis, Astrogliogenesis, and Myelination -- Chapter 11: Synaptic Formation and Elimination -- Chapter 12: Synaptic Maturation, Activity, and Plasticity -- Chapter 13: Adult Neurogenesis, Learning and Memory -- Chapter 14: Regulation of Sleep and Wakefulness -- PART III: General Pathophysiology of Microglia -- Chapter 15: Roles in Innate Immunity -- Chapter 16: Microglia and Systemic Immunity -- Chapter 17: Microglia and Microbiome-Gut-Brain Axis -- Chapter 18: Stress and Microglia: A Double-Edged Relationship -- Chapter 19: Substance Use and Addiction -- Chapter 20: Microglia and Sleep Disorders -- Chapter 21: Ageing -- Part IV: Microglia and Pathophysiology of Diseases of Nervous System -- Chapter 22: Neuropathic Pain -- Chapter 23: Role of Microglia in Stroke -- Chapter 24: Infectious Diseases including COVID-19 and HAND -- Chapter 25: Microglia and Multiple Sclerosis -- Chapter 26: Neurodevelopmental and Neuropsychiatric Disorders -- Chapter 27: Neurodegenerative Diseases -- Chapter 28: Microglia in Glioma -- PART V: Clinical Potential -- Chapter 29: Microglial Risk Alleles for Neurodegenerative Diseases (GWAS studies) -- Chapter 30: Emerging Models for the Study of Human Microglia in vitro (e.g. IPSCs, minibrains) -- Chapter 31: Emerging Models for the Study of Human Microglia ex vivo (comparison between human and rodent microglia) -- Chapter 32: Radiotracers for Microglial PET Imaging in vivo (focus on TSPO and its limitations) -- Chapter 33: Role of Microglial Modulation in Therapies for Perinatal Brain Injuries Leading to Neurodevelopmental Disorders -- Chapter 34: Metabolic Control of Microglial Function -- Chapter 35: Microglial Emerging Therapies and Targets under Clinical Trial -- Chapter 36: Epilogue. |
Record Nr. | UNINA-9910886079203321 |
Tremblay Marie-Ève
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024 | ||
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Lo trovi qui: Univ. Federico II | ||
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