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Behavioral Neurogenomics / / edited by Elisabeth B. Binder, Torsten Klengel
| Behavioral Neurogenomics / / edited by Elisabeth B. Binder, Torsten Klengel |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (264 pages) |
| Disciplina |
616.80442
616.84 |
| Collana | Current Topics in Behavioral Neurosciences |
| Soggetto topico |
Neurosciences
Human genetics Psychiatry Neuropsicologia clínica Genètica de la conducta Human Genetics |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-31265-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | GWAS of behavioral traits -- Genetic variation in long range enhancers -- DNA methylation and hydroxymethylation and behavior -- Social environment and epigenetics -- Histone modifications and behavior -- Cellular models of neuropsychiatric disorders -- miRNAs and anxiety related behaviors -- Transposable elements -- Inter and transgenerational effects on behavior. |
| Record Nr. | UNINA-9910373908403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical biology of neurodegeneration : a molecular approach / / Pedro Merino
| Chemical biology of neurodegeneration : a molecular approach / / Pedro Merino |
| Autore | Merino Pedro <1962-> |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , [2019] |
| Descrizione fisica | 1 online resource (381 pages) |
| Disciplina | 616.80442 |
| Soggetto topico | Nervous system - Degeneration - Molecular aspects |
| ISBN |
3-527-81345-4
3-527-81343-8 3-527-81342-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910555085703321 |
Merino Pedro <1962->
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| Weinheim, Germany : , : Wiley-VCH, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical biology of neurodegeneration : a molecular approach / / Pedro Merino
| Chemical biology of neurodegeneration : a molecular approach / / Pedro Merino |
| Autore | Merino Pedro <1962-> |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , [2019] |
| Descrizione fisica | 1 online resource (381 pages) |
| Disciplina | 616.80442 |
| Soggetto topico | Nervous system - Degeneration - Molecular aspects |
| ISBN |
3-527-81345-4
3-527-81343-8 3-527-81342-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830065403321 |
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Merino Pedro <1962->
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| Weinheim, Germany : , : Wiley-VCH, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DJ-1/PARK7 Protein : Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases / / edited by Hiroyoshi Ariga, Sanae M. M. Iguchi-Ariga
| DJ-1/PARK7 Protein : Parkinson’s Disease, Cancer and Oxidative Stress-Induced Diseases / / edited by Hiroyoshi Ariga, Sanae M. M. Iguchi-Ariga |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VIII, 222 p. 78 illus., 46 illus. in color.) |
| Disciplina | 616.80442 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer
Biochemistry Neurosciences Cytology Cancer Biology Neuroscience Cell Biology |
| ISBN | 981-10-6583-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface.- Chapter 1 Introduction/Overview -- Chapter 2 Structural Biology of the DJ-1 Superfamily -- Chapter 3 Expression of DJ-1 in patients with neurodegenerative diseases -- Chapter 4 DJ-1 as an oncogene and its clinical significance -- Chapter 5 Role of DJ-1 in fertilization -- Chapter 6 Anti-oxidative stress function of DJ-1 -- Chapter 7 Ttranscriptional regulation of DJ-1 -- Chapter 8 Regulation of Signal Transduction by DJ-1 -- Chapter 9 Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal -- Chapter 10 DJ-1 as a biomarker of Parkinson's disease -- Chapter 11 Roles of DJ-1 in diabetes mellitus -- Chapter 12 Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases -- Chapter 13 DJ-1 as an oncogene and promising target for cancer chemotherapy. . |
| Record Nr. | UNINA-9910253952403321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Gene therapy in neurological disorders / / edited by Mingjie Li, B. Joy Snider
| Gene therapy in neurological disorders / / edited by Mingjie Li, B. Joy Snider |
| Pubbl/distr/stampa | London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018] |
| Descrizione fisica | 1 online resource (450 pages) |
| Disciplina | 616.80442 |
| Soggetto topico |
Nervous system - Diseases - Gene therapy
Nervous System Diseases - therapy Genetic Therapy - methods Gene Expression Regulation |
| ISBN |
0-12-809821-X
0-12-809813-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910583477903321 |
| London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The molecular and cellular basis of neurodegenerative diseases : underlying mechanisms / / edited by Michael S. Wolfe
| The molecular and cellular basis of neurodegenerative diseases : underlying mechanisms / / edited by Michael S. Wolfe |
| Pubbl/distr/stampa | London, England : , : Academic Press, , [2018] |
| Descrizione fisica | 1 online resource (561 pages) |
| Disciplina | 616.80442 |
| Soggetto topico | Nervous system - Degeneration - Molecular aspects |
| ISBN |
0-12-811305-7
0-12-811304-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Solving the puzzle of neurodegeneration / Michael S. Wolfe -- Prion diseases / Robert C.C. Mercer, Alex J. McDonald, Erin Bove-Fenderson, Cheng Fang, Bei Wu and David A. Harris -- Alzheimer's Disease: toward a quantitative biological approach in describing its natural history and underlying mechanisms / Colin L. Masters, Ben Gu, Simon Laws, Yen Y Lim, Blaine Roberts, Victor L. Villemagne and Konrad Beyreuther --
Neurodegeneration and the ordered assembly of tau / Michel Goedert -- Amyotrophic lateral sclerosis and other TDP-43 proteinopathies / Jorge Gomez-Deza and Christopher E. Shaw -- Parkinson's disease and other synucleinopathies / Mark R. Cookson -- Huntington's disease and other polyglutamine repeat diseases: molecular mechanisms and pathogenic pathways / Audrey S. Dickey and Albert R. La Spada -- Prion-like propagation in neurogenerative diseases / Wouter Peelaerts, Veerle Baekelandt and Patrik Brundin -- Neurodegenerative diseases as protein folding disorders / Jermey D. Baker, Jack M. Webster, Lindsey B. Shelton, John Koren, III, Vladimir N. Uversky, Laura J. Blair and Chad A. Dickey -- Heat shock proteins and protein quality control in Alzheimer's disease / Fred W. Van Leeuwen and Harm H. Kampinga -- Neurodegenerative diseases and autophagy / Angeleen Fleming, Mariella Vicinanza, Maurizio Renna, Claudia Puri, Thomas Ricketts, Jens Füllgrabe, Ana Lopez, Sarah M. De Jager, Avraham Ashkenazi, Mariana Pavel, Floriana Licitra, Andrea Caricasole, Stephen P. Andrews, John Skidmore and David C. Rubinsztein -- Neurodegenerative Diseases and axonal transport / Lawrence S. Goldstein and Utpal Das -- Mitochondrial function and neurodegenerative diseases / Heather M. Wilkins, Ian Weidling, Scott Koppel, Xiaowan Wang, Alex Von Schulze and Russell H. Swerdlow -- Non-cell autonomous degeneration: role of astrocytes in neurodegenerative diseases / Sarah E. Smith and Azad Bonni -- Neurodegenerative diseases and RNA-mediated toxicity / Tiffany W. Todd and Leonard Petrucelli -- Neuroinflammation in are-related neurodegenerative diseases / Kathryn P. MacPherson, Maria E. De Sousa Rodrigues, Amarallys F. Cintron and Malú G. Tansey -- Neurodegenerative diseases and the aging brain / Stephen K. Godin, Jinsoo Seo and Li-Huei Tsai -- Index. |
| Record Nr. | UNINA-9910583382203321 |
| London, England : , : Academic Press, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurogenetics . Part I / / Daniel H. Geschwind, Henry L. Paulson, and Christine Klein, editors
| Neurogenetics . Part I / / Daniel H. Geschwind, Henry L. Paulson, and Christine Klein, editors |
| Pubbl/distr/stampa | Amsterdam, The Netherlands : , : Elsevier, , 2018 |
| Descrizione fisica | 1 online resource (417 pages) : illustrations |
| Disciplina | 616.80442 |
| Collana | Handbook of Clinical Neurology |
| Soggetto topico | Nervous system - Diseases - Genetic aspects |
| ISBN |
0-444-63235-2
0-444-63233-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910583017103321 |
| Amsterdam, The Netherlands : , : Elsevier, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polyglutamine Disorders / / edited by Clévio Nóbrega, Luís Pereira de Almeida
| Polyglutamine Disorders / / edited by Clévio Nóbrega, Luís Pereira de Almeida |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (469 pages) : illustrations, tables |
| Disciplina | 616.80442 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Neurosciences
Neurology Medical genetics Neurology Gene Function |
| ISBN | 3-319-71779-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910298438203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration / / edited by Henning Ulrich, Peter Illes, Talita Glaser
| Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration / / edited by Henning Ulrich, Peter Illes, Talita Glaser |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (381 pages) |
| Disciplina | 616.80442 |
| Soggetto topico |
Neurosciences
Neurochemistry Medicine—Research Biology—Research Regenerative medicine Neuroscience Biomedical Research Regenerative Medicine and Tissue Engineering |
| ISBN | 3-031-26945-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation. |
| Record Nr. | UNINA-9910734874703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rosenberg's molecular and genetic basis of neurological and psychiatric disease / / edited by Roger N. Rosenberg, Juan M. Pascual
| Rosenberg's molecular and genetic basis of neurological and psychiatric disease / / edited by Roger N. Rosenberg, Juan M. Pascual |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (1465 p.) |
| Disciplina | 616.80442 |
| Soggetto topico |
Nervous system - Diseases - Molecular aspects
Nervous system - Diseases - Genetic aspects |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-12-410549-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease; Copyright; Dedications; Contents; Preface to the Fifth Edition; Contributors; Section I: General Concepts and Tools; Chapter 1: Mendelian, Non-Mendelian, Multigenic Inheritance, and Epigenetics; Introduction; Mendelian traits; Mendel's Laws; Chromosomes and Genes; Mendelian Inheritance; Molecular Pathomechanisms of Mutations; Factors That Modify Classic Mendelian Inheritance Patterns; New Mutations, Mosaicism, and Somatic Mutations; Penetrance and Expressivity; Repeat expansion disorders
Non-mendelian inheritanceMitochondrial Inheritance; Imprinting; Uniparental Disomy; Imprinting, UPD, and Genetic Disorders; Chromosomal and genomic disorders; Aneuploidy; lsochromosomes; Translocations; Intrachromosomal Rearrangements; Mechanisms for Formation of Chromosomal Rearrangements; Nonallelic homologous recombination (NAHR); Nonhomologous end joining (NHEJ); Fork stalling and template switching/microhomology-mediated break-induced replication (FoSTeS/MMBIR); How Chromosomal Rearrangements Confer Phenotypes; Assays for Chromosomal and Genomic Disorders; Multigenic inheritance Digenic InheritanceModifier Genes; Complex traits; Genetic Features of Complex Traits; Assessing Variation in the Human Genome; Genetic Variation and Complex Traits; Examples of Susceptibility Genes for Complex Traits; Epigenetics; DNA Methylation and Hydroxymethylation; Histone Modifications and Higher Order Chromatin Remodeling; Noncoding RNA Regulation; The human genome: High-throughput technologies; Conclusions; References; Chapter 2: Genotype-Phenotype Correlations; Introduction; Single phenotype: Multiple genes; Single gene: Multiple phenotypes; Neuronal/cellular selective vulnerability Highly variable systemic phenotypesPenetrance and age of onset; Conclusion and future directions; References; Chapter 3: Immunogenetics of Neurological Disease; Introduction; Epidemiological evidence for genetic susceptibility; Genetics of MS: Family-based investigations; The role of major histocompatibility complex genes; Other immune-related genes; The environment and immune-related genes; Conclusion; References; Chapter 4: Pharmacogenomic Approaches to the Treatment of Sporadic Alzheimer Disease using Cholinomimetic Agents; Introduction; Genetic risk factors and sporadic alzheimer disease Genetic risk factors, cholinergic dysfunction, and alzheimer diseaseApoE4 and cholinomimetic drugs in alzheimer disease; Experimental drugs and their relationship to the apoE4 allele; Acetylcholinesterase and butyrylcholinesterase genetic variants in dementia; Acknowledgements; References; Chapter 5: Application of Mouse Genetics to Human Disease: Generation and Analysis of Mouse Models; Generation and Analysis of Mouse Models; Introduction; Creating mouse models; Transgenesis; Gene Targeting; Random Mutagenesis; Phenotypic analysis of mouse models; Summary; References Chapter 6: DNA Sequencing and Other Methods of Exonic and Genomic Analyses |
| Record Nr. | UNINA-9910460248803321 |
| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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