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The effects of estrogen on brain function [[electronic resource] /] / edited by Natalie L. Rasgon
| The effects of estrogen on brain function [[electronic resource] /] / edited by Natalie L. Rasgon |
| Pubbl/distr/stampa | Baltimore, : Johns Hopkins University Press, 2006 |
| Descrizione fisica | 1 online resource (181 p.) |
| Disciplina | 616.8/0461 |
| Altri autori (Persone) | RasgonNatalie L |
| Soggetto topico |
Cognition disorders - Endocrine aspects
Estrogen - Therapeutic use - Complications Brain - Effect of drugs on Menopause - Hormone therapy - Complications |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-8018-8890-5 |
| Classificazione | 77.50 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preclinical data relating to estrogen's effects on cognitive performance / Robert B. Gibbs -- The short-lived effects of hormone therapy on cognitive function / Eva Hogervorst -- Clinical data from structural and functional brain imaging on estrogen's effects in the central nervous system / Daniel H.S. Silverman, Cheri L. Geist, and Natalie L. Rasgon -- Clinical data on estrogen's effects on mood / Natalie L. Rasgon, Laurel N. Zappert, and Katherine E. Williams -- Preclinical efforts to develop effective neuroSERMs for the brain / Roberta Diaz Brinton and Liqin Zhao -- Basic and clinical data on the effects of SERMs on cognition / Kristine Yaffe, Pauline M. Maki, and Peter J. Schmidt. |
| Record Nr. | UNINA-9910451890703321 |
| Baltimore, : Johns Hopkins University Press, 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The effects of estrogen on brain function [[electronic resource] /] / edited by Natalie L. Rasgon
| The effects of estrogen on brain function [[electronic resource] /] / edited by Natalie L. Rasgon |
| Pubbl/distr/stampa | Baltimore, : Johns Hopkins University Press, 2006 |
| Descrizione fisica | 1 online resource (181 p.) |
| Disciplina | 616.8/0461 |
| Altri autori (Persone) | RasgonNatalie L |
| Soggetto topico |
Cognition disorders - Endocrine aspects
Estrogen - Therapeutic use - Complications Brain - Effect of drugs on Menopause - Hormone therapy - Complications |
| ISBN | 0-8018-8890-5 |
| Classificazione | 77.50 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preclinical data relating to estrogen's effects on cognitive performance / Robert B. Gibbs -- The short-lived effects of hormone therapy on cognitive function / Eva Hogervorst -- Clinical data from structural and functional brain imaging on estrogen's effects in the central nervous system / Daniel H.S. Silverman, Cheri L. Geist, and Natalie L. Rasgon -- Clinical data on estrogen's effects on mood / Natalie L. Rasgon, Laurel N. Zappert, and Katherine E. Williams -- Preclinical efforts to develop effective neuroSERMs for the brain / Roberta Diaz Brinton and Liqin Zhao -- Basic and clinical data on the effects of SERMs on cognition / Kristine Yaffe, Pauline M. Maki, and Peter J. Schmidt. |
| Record Nr. | UNINA-9910778350003321 |
| Baltimore, : Johns Hopkins University Press, 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth factors as drugs for neurological and sensory disorders [[electronic resource] /] / [editors, Gregory R. Bock (organizer) and Jamie A. Goode]
| Growth factors as drugs for neurological and sensory disorders [[electronic resource] /] / [editors, Gregory R. Bock (organizer) and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1996 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
599.08265
616.8/0461 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Nervous system - Degeneration - Chemotherapy
Nerve growth factor - Therapeutic use Neurotropin - Therapeutic use Growth factors - Therapeutic use Afferent pathways - Diseases - Chemotherapy Sensory disorders - Chemotherapy |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-12246-0
9786612122460 0-470-51486-8 0-470-51487-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH FACTORS AS DRUGS FOR NEUROLOGICAL AND SENSORY DISORDERS; Contents; Participants; Introduction; Motor neuron disease and model systems: aetiologies, mechanisms and therapies; Potential utility of rhlGF-1 in neu romuscular and/or degenerative disease; Therapeutic potential of the n e u rot ro p h i n s and n e u rot ro p h i n-C NT F combinations in peripheral neuropathies and motor neuron diseases; Development of neurotrophic factor therapy for Alzheimer's disease
Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-bSomatic gene therapy for nervous system disease; Neurotrophic factors in the treatment of peripheral neuropathy; General discussion I; Growth factors in the treatment of degenerative retinal disorders; Effects of neurotrophins on the survival and regrowth of injured retinal neurons; Neurotrophic factors as pharmacological agents for the treatment of injured auditory neurons; Growth factors as potential drugs for the sensory epithelia of the ear Factors affecting neuronal birth and death in the mammalian olfactory epithelium The problems of delivering neuroactive molecules to the CNS; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144011503321 |
| Chichester ; ; New York, : Wiley, 1996 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth factors as drugs for neurological and sensory disorders [[electronic resource] /] / [editors, Gregory R. Bock (organizer) and Jamie A. Goode]
| Growth factors as drugs for neurological and sensory disorders [[electronic resource] /] / [editors, Gregory R. Bock (organizer) and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1996 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina |
599.08265
616.8/0461 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Nervous system - Degeneration - Chemotherapy
Nerve growth factor - Therapeutic use Neurotropin - Therapeutic use Growth factors - Therapeutic use Afferent pathways - Diseases - Chemotherapy Sensory disorders - Chemotherapy |
| ISBN |
1-282-12246-0
9786612122460 0-470-51486-8 0-470-51487-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH FACTORS AS DRUGS FOR NEUROLOGICAL AND SENSORY DISORDERS; Contents; Participants; Introduction; Motor neuron disease and model systems: aetiologies, mechanisms and therapies; Potential utility of rhlGF-1 in neu romuscular and/or degenerative disease; Therapeutic potential of the n e u rot ro p h i n s and n e u rot ro p h i n-C NT F combinations in peripheral neuropathies and motor neuron diseases; Development of neurotrophic factor therapy for Alzheimer's disease
Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-bSomatic gene therapy for nervous system disease; Neurotrophic factors in the treatment of peripheral neuropathy; General discussion I; Growth factors in the treatment of degenerative retinal disorders; Effects of neurotrophins on the survival and regrowth of injured retinal neurons; Neurotrophic factors as pharmacological agents for the treatment of injured auditory neurons; Growth factors as potential drugs for the sensory epithelia of the ear Factors affecting neuronal birth and death in the mammalian olfactory epithelium The problems of delivering neuroactive molecules to the CNS; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910831001003321 |
| Chichester ; ; New York, : Wiley, 1996 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth factors as drugs for neurological and sensory disorders / / [editors, Gregory R. Bock (organizer) and Jamie A. Goode]
| Growth factors as drugs for neurological and sensory disorders / / [editors, Gregory R. Bock (organizer) and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1996 |
| Descrizione fisica | 1 online resource (265 p.) |
| Disciplina | 616.8/0461 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Nervous system - Degeneration - Chemotherapy
Nerve growth factor - Therapeutic use Neurotropin - Therapeutic use Growth factors - Therapeutic use Afferent pathways - Diseases - Chemotherapy Sensory disorders - Chemotherapy |
| ISBN |
9786612122460
9781282122468 1282122460 9780470514863 0470514868 9780470514870 0470514876 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH FACTORS AS DRUGS FOR NEUROLOGICAL AND SENSORY DISORDERS; Contents; Participants; Introduction; Motor neuron disease and model systems: aetiologies, mechanisms and therapies; Potential utility of rhlGF-1 in neu romuscular and/or degenerative disease; Therapeutic potential of the n e u rot ro p h i n s and n e u rot ro p h i n-C NT F combinations in peripheral neuropathies and motor neuron diseases; Development of neurotrophic factor therapy for Alzheimer's disease
Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-bSomatic gene therapy for nervous system disease; Neurotrophic factors in the treatment of peripheral neuropathy; General discussion I; Growth factors in the treatment of degenerative retinal disorders; Effects of neurotrophins on the survival and regrowth of injured retinal neurons; Neurotrophic factors as pharmacological agents for the treatment of injured auditory neurons; Growth factors as potential drugs for the sensory epithelia of the ear Factors affecting neuronal birth and death in the mammalian olfactory epithelium The problems of delivering neuroactive molecules to the CNS; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9911020245403321 |
| Chichester ; ; New York, : Wiley, 1996 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Handbook of Neuroemergency Clinical Trials
| Handbook of Neuroemergency Clinical Trials |
| Autore | Skolnick Brett E |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Saint Louis : , : Elsevier Science & Technology, , 2017 |
| Descrizione fisica | 1 online resource (408 pages) |
| Disciplina | 616.8/0461 |
| Altri autori (Persone) | AlvesWayne M |
| Soggetto topico |
Nervous system - Diseases
Neuropharmacology Clinical trials |
| ISBN |
9780128040645
0128040645 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover -- HANDBOOK OF NEUROEMERGENCY CLINICAL TRIALS -- HANDBOOK OF NEUROEMERGENCY CLINICAL TRIALS -- Copyright -- Dedications -- Contents -- List of Contributors -- Introduction -- CURRENT STATUS OF TREATMENT OF NEUROEMERGENCIES -- ACUTE NEUROCLINICAL TRIALS -- PURPOSE OF THIS VOLUME -- References -- 1 - ACUTE ISCHEMIC STROKEPARTI -- 1 - Acute Ischemic Stroke -- INTRODUCTION -- TRIALS OF REPERFUSION THERAPIES FOR ISCHEMIC STROKE -- Stroke Alteplase Thrombolysis Trials -- The NINDS tPA Trial -- ECASS 1 and 2 Trials -- ATLANTIS Trial -- ECASS 3 Trial -- EPITHET Trial -- IST-3 Trial -- Metaanalyses of Thrombolysis Trials -- Phase 4 Data: Postmarketing Studies in Alteplase Stroke Thrombolysis -- Future Priorities -- Implementation -- Ongoing Trials and Future Directions -- Endovascular Revascularization Trials -- Early Mechanical Thrombectomy Trials -- Endovascular Thrombectomy Using Stent Retrievers -- Metaanalyses of Thrombectomy Trials -- Major Unresolved Questions Around Endovascular Thrombectomy -- ANTITHROMBOTIC DRUGS -- NEUROPROTECTIVE DRUGS IN ACUTE ISCHEMIC STROKE -- STUMBLING FROM THE BENCH TO BEDSIDE -- PHYSIOLOGICAL MODIFICATION OF THE ISCHEMIC ENVIRONMENT -- CONCLUSIONS -- References -- 2 - Subarachnoid Hemorrhage -- CHARACTERISTICS OF THE DISEASE -- Etiology-Why Do Studies Restrict Inclusion to Aneurysmal Subarachnoid Hemorrhage? -- Pathophysiology Considerations Relevant to Clinical Trials -- Clinical Features and Diagnosis -- GUIDELINES FOR MANAGEMENT OF SUBARACHNOID HEMORRHAGE -- SUCCESSES AND DISAPPOINTMENTS -- Ineffective Interventions -- Treatment Side Effects -- Sample Size and Outcome Measures -- The Quagmire of Rescue Therapy -- Center Variation and Practice Misalignment -- Multifactorial Nature of Delayed Cerebral Ischemia and Prognostic Factors for Outcome -- SUBPOPULATIONS AND OUTCOMES AND THEIR ASSESSMENT.
BIOMARKERS AND SURROGATE ENDPOINTS -- PHARMACOKINETICS AND PHARMACODYNAMICS -- CONSENSUS REGARDING FAILURES AND POSSIBLE SOLUTIONS -- CURRENT "STATE OF PRACTICE" IN DESIGN AND ANALYSIS OF RANDOMIZED CONTROLLED TRIALS FOR SUBARACHNOID HEMORRHAGE -- Disclosures -- References -- 3 - Clinical Trials in Spontaneous Intracerebral Hemorrhage -- INTRODUCTION -- HEMATOMA GROWTH -- Blood Pressure -- Hemostasis -- NEUROPROTECTION -- Cerebral Edema -- Neuroinflammation -- Iron Toxicity/Chelation -- Apoptosis -- Cryoprotection -- SURGERY -- CONCLUSIONS -- References -- 4 - Imaging Biomarkers in Stroke Trials -- INTRODUCTION AND DESCRIPTION OF IMAGING BIOMARKERS -- IMAGING OF INTRALUMINAL THROMBUS -- VASCULAR IMAGING -- COLLATERAL ARTERIAL SUPPLY -- ISCHEMIC CORE AND PENUMBRA -- PREDICTIVE VERSUS PROGNOSTIC BIOMARKERS -- UTILITY OF IMAGING BIOMARKERS -- CONCLUSIONS AND FUTURE DIRECTIONS -- References -- II - TRAUMATIC BRAIN INJURY -- 5 - Traumatic Brain Injury -- INTRODUCTION -- HISTORICAL CONTEXT OF TRAUMATIC BRAIN INJURY TRIALS -- DRUG DEVELOPMENT PROGRAMS FOR TRAUMATIC BRAIN INJURY -- Underlying Logic of Traumatic Brain Injury Trials -- Classes of Novel Drugs Tested in Traumatic Brain Injury -- DRUGS AND TREATMENTS TESTED TO DATE FOR TRAUMATIC BRAIN INJURY -- Barbiturates -- High-Dose Corticosteroids -- Tromethamine (THAM) -- ION CHANNEL BLOCKERS -- Free Radical Scavengers -- Glutamate Antagonists -- Glutamate Agonists -- CDP-Choline -- Immune System Modulators -- Statins -- Progesterone -- Hypothermia -- WHY HAVE TRAUMATIC BRAIN INJURY TRIALS PROVEN TO BE SO DIFFICULT? -- KEY ISSUES IN TRAUMATIC BRAIN INJURY CLINICAL TRIAL DESIGN -- Multiplicity of Injuries -- Anatomic Classification of Traumatic Brain Injury -- Treatment-Related Problems -- Limitations of Traumatic Brain Injury Classification -- Limitations of the Outcome Measures -- Glasgow Coma Scale. CT Classification of Traumatic Brain Injury Population -- Prognostic Factors -- Glasgow Outcome Scale -- Outcomes in Traumatic Brain Injury Clinical Trials -- Time Course of Recovery -- Respecifying the Glasgow Outcome Scale -- Shape of Outcome Distribution -- Pharmacokinetic-Pharmacodynamic Correlations -- Censoring Treatment Populations -- CONCLUSIONS -- References -- 6 - Improving Approaches to Evaluate Efficacy and Safety of Drugs for Traumatic Brain Injury -- TRANSLATIONAL APPROACHES -- Extended Experimental Studies -- Better Characterization of Disease Biology and Drug Distribution in Human Traumatic Brain Injury -- IMPROVING TRIAL DESIGN AND ANALYSIS -- Heterogeneity and Statistical Power -- Heterogeneity and Risk of Imbalances -- Dealing With Heterogeneity in Efficacy Analysis -- ALTERNATIVE STRATEGIES TO EXPLORING CLINICAL EFFICACY -- References -- 7 - Brain Imaging in Traumatic Brain Injury -- INTRODUCTION -- TYPES OF BRAIN INJURIES -- Primary Injuries -- Secondary Injuries -- CLASSIFICATION OF TRAUMATIC BRAIN INJURY -- Imaging Modalities -- Conventional Radiography -- Ultrasound -- Computed Tomography -- Computed Tomography Angiography -- Conventional Magnetic Resonance Imaging -- Advanced Techniques -- Diffusion Weighted Imaging-Diffusion Tensor Imaging -- Functional Magnetic Resonance Imaging -- Perfusion Imaging -- Magnetic Resonance Spectroscopy -- Magnetization Transfer Imaging -- Magnetoencephalography -- Single-Photon Emission Computed Tomography -- Positron Emission Tomography -- IMPLICATIONS AND CHALLENGES FOR CLINICAL TRIALS -- CONCLUSION -- References -- 8 - The Use of Blood-Based Biomarkers to Improve the Design of Clinical Trials of Traumatic Brain Injury -- INTRODUCTION -- Traumatic Brain Injury Diagnostics -- Traumatic Brain Injury Management. Recent Successes and Disappointments of Clinical Trials for Novel Drugs to Treat Traumatic Brain Injury Management -- Promises of Biomarker Applications in Traumatic Brain Injury Clinical Trials -- SUMMARY OF SEARCH OF CLINICAL TRIALS IN TRAUMATIC BRAIN INJURY USING BIOMARKERS -- SURROGATE ENDPOINTS AND SELECTION OF CENTRAL NERVOUS SYSTEM-SPECIFIC PROTEIN BIOMARKERS FOR SEVERE TRAUMATIC BRAIN INJURY DIAGNO... -- Biomarkers Potentially Useful in Traumatic Brain Injury Trials -- Biomarkers of Glial Injury -- Glial Fibrillary Acidic Protein -- S100 Calcium Binding Protein B (S100B) -- Biomarkers of Neuronal Injury -- Ubiquitin Carboxy-Terminal Hydrolase L1 -- αII-Spectrin Breakdown Products 120, 145, and 150 (SBDP120, SBDP145, SBDP150) -- Microtubule-Associated Protein 2 -- Myelin Basic Protein and Its Autoantibody -- Neuron-Specific Enolase -- Neurofilaments -- Total Tau and Its Cleaved Forms -- Biomarkers of Inflammation and Vascular Injury -- Cytokines -- Cell Adhesion Molecules -- Other Biomarkers -- MicroRNAs -- DISCUSSION -- Improving of the Study Design Using Blood-Based Biomarkers and Their Combination With Other Outcomes Measures -- Statistical Considerations in Clinical Trials Using Biomarker Studies -- PROSPECTS AND PATHWAYS FOR INCORPORATION OF BLOOD-BASED BIOMARKERS INTO THE DESIGN OF CLINICAL TRIALS FOR TRAUMATIC BRAIN INJURY... -- References -- 9 - Biostatistical Issues in TBI Clinical Trials -- INTRODUCTION -- CLINICAL TRIAL DESIGN -- Dose-Finding Designs -- Selection Designs -- Futility Designs -- Confirmatory Designs -- Adaptive Designs -- APPROACHES TO RANDOMIZATION -- Achieving Balance With Respect to Known Prognostic Variables -- Covariate-Adaptive Randomization -- Response-Adaptive Randomization -- Comparing Baseline Characteristics in a Randomized Trial -- OUTCOME MEASURES -- Glasgow Outcome Scale/Glasgow Outcome Scale Extended. Performance-Based Measures -- Patient-Reported Outcomes -- Clinician-Reported Outcomes -- Biomarkers -- ANALYTICAL APPROACHES -- The Fixed Dichotomy -- The Sliding Dichotomy -- Ordinal Analysis -- MISSING DATA -- MULTIPLICITY -- SUBGROUP ANALYSIS -- ASSESSMENTS CONDUCTED OVER TIME -- HETEROGENEITY OF THE PATIENT POPULATION -- SUMMARY -- References -- III - SEIZURE EMERGENCIES -- 10 - Acute Seizures and Status Epilepticus -- OVERVIEW -- DIAGNOSIS AND DEFINITION OF STATUS EPILEPTICUS -- CLASSIFICATION OF STATUS EPILEPTICUS -- Semiology -- Etiology -- Electroencephalographic Correlates -- Age -- ANIMAL MODELS: RELEVANT ISSUES FOR CLINICAL DEVELOPMENT PROGRAMS -- EPIDEMIOLOGY AND NATURAL HISTORY -- Acute Repetitive Seizures -- Generalized Convulsive Status Epilepticus -- Refractory Status Epilepticus -- Super-refractory Status Epilepticus -- Nonconvulsive Status Epilepticus -- MECHANISMS OF DISEASE AND PATHOLOGY -- DIAGNOSIS AND SUBPOPULATIONS -- Severity of Injury Measures -- Seizure Type -- Level of Consciousness -- Duration -- Response to Treatment (Status Epilepticus Stage) -- Etiology -- Concomitant Medical Illnesses -- Defining Relevant Treatment Populations -- Defining Good and Poor Prognoses -- Relevant Prognostic Factors for Defining Inclusion and Exclusion Criteria -- Subsetting Patients for Planned and Ad Hoc Comparisons -- CURRENT DISEASE MANAGEMENT AND CONTROVERSIES -- Initial Management Steps -- Prevention of Status Epilepticus: Acute Repetitive Seizures -- Generalized Convulsive Status Epilepticus -- Early Status Epilepticus Treatment -- Established Status Epilepticus -- Refractory Status Epilepticus and Super-refractory Status Epilepticus -- Nonconvulsive Status Epilepticus -- Specific Drugs -- ISSUES IN CLINICAL PROTOCOL DEVELOPMENT -- Time to Treatment -- Operational Definitions of Status Epilepticus -- Site Selection -- Sample Size. Treatment Selection. |
| Record Nr. | UNINA-9910583058203321 |
Skolnick Brett E
|
||
| Saint Louis : , : Elsevier Science & Technology, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neuropsychopharmacology : an official publication of the American College of Neuropsychopharmacology / / Kenneth L. Davis [and three others], editors
| Neuropsychopharmacology : an official publication of the American College of Neuropsychopharmacology / / Kenneth L. Davis [and three others], editors |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2002 |
| Descrizione fisica | 1 online resource (2054 p.) |
| Disciplina | 616.8/0461 |
| Soggetto topico |
Neuropsychopharmacology
Neurobehavioral disorders |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-4698-7903-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Copyright""; ""Editors ""; ""Preface""; ""Contents""; ""Section I - Neurotransmitters and Signal Transduction""; ""Neurotransmitters and Signal Transduction - Introduction""; ""1 - Acetylcholine""; ""2 - Serotonin""; ""3 - Opioid Peptides and Their Receptors: Overview and Function in Pain Modulation""; ""4 - Norepinephrine""; ""5 - Regulation of G Protein-Coupled Receptors by Phosphorylation and Endocytosis""; ""6 - The Diverse Roles of L-Glutamic Acid in Brain Signal Transduction""
""7 - Corticotropin-Releasing Factor: Physiology, Pharmacology, and Role in Central Nervous System Disorders""""8 - Neurogenesis in Adult Brain""; ""9 - Dopamine""; ""10 - Astrocytes""; ""11 - Synaptic Plasticity""; ""12 - Gaba""; ""13 - Substance P and Related Tachykinins""; ""14 - Histamine""; ""15 - Purinergic Neurotransmission""; ""16 - Neurotrophic Factors and Intracellular Signal Transduction Pathways""; ""17 - Regulation of Gene Expression""; ""Section II - Emerging Methods in Molecular Biology and Genetics""; ""Emerging Methods in Molecular Biology and Genetics - Introduction"" ""18 - Using Human Genomics to Advance Neuropsychopharmacology""""19 - Gene Targeting and Transgenic Technologies""; ""20 - Gene Delivery into the Brain Using Viral Vectors""; ""21 - Neuropsychopharmacology of Worms and Flies""; ""22 - Beyond Binding: Molecular and Cell Biological Approaches to Studying G-Protein�Coupled Receptors""; ""23 - Applying Functional Genomics to Neuropsychopharmacology""; ""Section III - Emerging Imaging Technologies and Their Application to Psychiatric Research""; ""Emerging Imaging Technologies and Their Application to Psychiatric Research -Introduction"" ""24 - Automated 3D Analysis of Large Brain Mri Databases""""25 - In Vivo Magnetic Resonance Spectroscopy Studies of the Glutamate and Gaba Neurotransmitter Cycles and Functional Neuroenergetics""; ""26 - The Spatial, Temporal, and Interpretive Limits of Functional MRI""; ""27 - Diffusion Tensor Imaging""; ""28 - Activation Paradigms in Affective and Cognitive Neuroscience: Probing the Neuronal Circuitry Underlying Mood and Anxiety Disorders""; ""29 - Interactions Among Neuronal Systems Assessed with Functional Neuroimaging"" ""30 - Measuring Brain Connectivity with Functional Imaging and Transcranial Magnetic Stimulation""""31 - In Vivo Molecular Imaging: Ligand Development and Research Applications""; ""32 - Event-Related Potentials and Magnetic Fields in the Human Brain""; ""Section IV - Drug Discovery and Evaluation""; ""Drug Discovery and Evaluation - Introduction""; ""33 - The Role of Preclinical Models in the Development of Psychotropic Drugs""; ""34 - Proof of Concept: Functional Models for Drug Development in Humans ""; ""35 - Ethical Aspects of Neuropsychiatric Research with Human Subjects"" ""36 - Regulatory Issues"" |
| Record Nr. | UNINA-9910454250603321 |
| Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neuropsychopharmacology : an official publication of the American College of Neuropsychopharmacology / / Kenneth L. Davis [and three others], editors
| Neuropsychopharmacology : an official publication of the American College of Neuropsychopharmacology / / Kenneth L. Davis [and three others], editors |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2002 |
| Descrizione fisica | 1 online resource (2054 p.) |
| Disciplina | 616.8/0461 |
| Soggetto topico |
Neuropsychopharmacology
Neurobehavioral disorders |
| ISBN | 1-4698-7903-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Copyright""; ""Editors ""; ""Preface""; ""Contents""; ""Section I - Neurotransmitters and Signal Transduction""; ""Neurotransmitters and Signal Transduction - Introduction""; ""1 - Acetylcholine""; ""2 - Serotonin""; ""3 - Opioid Peptides and Their Receptors: Overview and Function in Pain Modulation""; ""4 - Norepinephrine""; ""5 - Regulation of G Protein-Coupled Receptors by Phosphorylation and Endocytosis""; ""6 - The Diverse Roles of L-Glutamic Acid in Brain Signal Transduction""
""7 - Corticotropin-Releasing Factor: Physiology, Pharmacology, and Role in Central Nervous System Disorders""""8 - Neurogenesis in Adult Brain""; ""9 - Dopamine""; ""10 - Astrocytes""; ""11 - Synaptic Plasticity""; ""12 - Gaba""; ""13 - Substance P and Related Tachykinins""; ""14 - Histamine""; ""15 - Purinergic Neurotransmission""; ""16 - Neurotrophic Factors and Intracellular Signal Transduction Pathways""; ""17 - Regulation of Gene Expression""; ""Section II - Emerging Methods in Molecular Biology and Genetics""; ""Emerging Methods in Molecular Biology and Genetics - Introduction"" ""18 - Using Human Genomics to Advance Neuropsychopharmacology""""19 - Gene Targeting and Transgenic Technologies""; ""20 - Gene Delivery into the Brain Using Viral Vectors""; ""21 - Neuropsychopharmacology of Worms and Flies""; ""22 - Beyond Binding: Molecular and Cell Biological Approaches to Studying G-Protein�Coupled Receptors""; ""23 - Applying Functional Genomics to Neuropsychopharmacology""; ""Section III - Emerging Imaging Technologies and Their Application to Psychiatric Research""; ""Emerging Imaging Technologies and Their Application to Psychiatric Research -Introduction"" ""24 - Automated 3D Analysis of Large Brain Mri Databases""""25 - In Vivo Magnetic Resonance Spectroscopy Studies of the Glutamate and Gaba Neurotransmitter Cycles and Functional Neuroenergetics""; ""26 - The Spatial, Temporal, and Interpretive Limits of Functional MRI""; ""27 - Diffusion Tensor Imaging""; ""28 - Activation Paradigms in Affective and Cognitive Neuroscience: Probing the Neuronal Circuitry Underlying Mood and Anxiety Disorders""; ""29 - Interactions Among Neuronal Systems Assessed with Functional Neuroimaging"" ""30 - Measuring Brain Connectivity with Functional Imaging and Transcranial Magnetic Stimulation""""31 - In Vivo Molecular Imaging: Ligand Development and Research Applications""; ""32 - Event-Related Potentials and Magnetic Fields in the Human Brain""; ""Section IV - Drug Discovery and Evaluation""; ""Drug Discovery and Evaluation - Introduction""; ""33 - The Role of Preclinical Models in the Development of Psychotropic Drugs""; ""34 - Proof of Concept: Functional Models for Drug Development in Humans ""; ""35 - Ethical Aspects of Neuropsychiatric Research with Human Subjects"" ""36 - Regulatory Issues"" |
| Record Nr. | UNINA-9910777738903321 |
| Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neuropsychopharmacology : an official publication of the American College of Neuropsychopharmacology / / Kenneth L. Davis [and three others], editors
| Neuropsychopharmacology : an official publication of the American College of Neuropsychopharmacology / / Kenneth L. Davis [and three others], editors |
| Edizione | [Fifth edition.] |
| Pubbl/distr/stampa | Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2002 |
| Descrizione fisica | 1 online resource (2054 p.) |
| Disciplina | 616.8/0461 |
| Soggetto topico |
Neuropsychopharmacology
Neurobehavioral disorders |
| ISBN | 1-4698-7903-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Copyright""; ""Editors ""; ""Preface""; ""Contents""; ""Section I - Neurotransmitters and Signal Transduction""; ""Neurotransmitters and Signal Transduction - Introduction""; ""1 - Acetylcholine""; ""2 - Serotonin""; ""3 - Opioid Peptides and Their Receptors: Overview and Function in Pain Modulation""; ""4 - Norepinephrine""; ""5 - Regulation of G Protein-Coupled Receptors by Phosphorylation and Endocytosis""; ""6 - The Diverse Roles of L-Glutamic Acid in Brain Signal Transduction""
""7 - Corticotropin-Releasing Factor: Physiology, Pharmacology, and Role in Central Nervous System Disorders""""8 - Neurogenesis in Adult Brain""; ""9 - Dopamine""; ""10 - Astrocytes""; ""11 - Synaptic Plasticity""; ""12 - Gaba""; ""13 - Substance P and Related Tachykinins""; ""14 - Histamine""; ""15 - Purinergic Neurotransmission""; ""16 - Neurotrophic Factors and Intracellular Signal Transduction Pathways""; ""17 - Regulation of Gene Expression""; ""Section II - Emerging Methods in Molecular Biology and Genetics""; ""Emerging Methods in Molecular Biology and Genetics - Introduction"" ""18 - Using Human Genomics to Advance Neuropsychopharmacology""""19 - Gene Targeting and Transgenic Technologies""; ""20 - Gene Delivery into the Brain Using Viral Vectors""; ""21 - Neuropsychopharmacology of Worms and Flies""; ""22 - Beyond Binding: Molecular and Cell Biological Approaches to Studying G-Protein�Coupled Receptors""; ""23 - Applying Functional Genomics to Neuropsychopharmacology""; ""Section III - Emerging Imaging Technologies and Their Application to Psychiatric Research""; ""Emerging Imaging Technologies and Their Application to Psychiatric Research -Introduction"" ""24 - Automated 3D Analysis of Large Brain Mri Databases""""25 - In Vivo Magnetic Resonance Spectroscopy Studies of the Glutamate and Gaba Neurotransmitter Cycles and Functional Neuroenergetics""; ""26 - The Spatial, Temporal, and Interpretive Limits of Functional MRI""; ""27 - Diffusion Tensor Imaging""; ""28 - Activation Paradigms in Affective and Cognitive Neuroscience: Probing the Neuronal Circuitry Underlying Mood and Anxiety Disorders""; ""29 - Interactions Among Neuronal Systems Assessed with Functional Neuroimaging"" ""30 - Measuring Brain Connectivity with Functional Imaging and Transcranial Magnetic Stimulation""""31 - In Vivo Molecular Imaging: Ligand Development and Research Applications""; ""32 - Event-Related Potentials and Magnetic Fields in the Human Brain""; ""Section IV - Drug Discovery and Evaluation""; ""Drug Discovery and Evaluation - Introduction""; ""33 - The Role of Preclinical Models in the Development of Psychotropic Drugs""; ""34 - Proof of Concept: Functional Models for Drug Development in Humans ""; ""35 - Ethical Aspects of Neuropsychiatric Research with Human Subjects"" ""36 - Regulatory Issues"" |
| Record Nr. | UNINA-9910808303303321 |
| Philadelphia, Pennsylvania : , : Lippincott Williams & Wilkins, , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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