Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Environmental impacts on reproductive health and fertility / / edited by Tracey J. Woodruff [and three others] [[electronic resource]]
| Environmental impacts on reproductive health and fertility / / edited by Tracey J. Woodruff [and three others] [[electronic resource]] |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2010 |
| Descrizione fisica | 1 online resource (xi, 250 pages) : digital, PDF file(s) |
| Disciplina | 616.6/5071 |
| Collana | Cambridge medicine |
| Soggetto topico |
Reproductive toxicology
Reproductive health - Environmental aspects |
| ISBN |
1-107-20722-3
1-282-54698-8 9786612546983 0-511-67423-6 0-511-67542-9 0-511-67217-9 0-511-67089-3 0-511-67468-6 0-511-67344-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: 1. Introduction Tracey J. Woodruff and Linda C. Giudice; 2. Environmental contaminants and exposure Mary A. Fox and Yutaka Aoki; 3. Development and maturation of the normal female reproductive system: 3.1. Ovary Laxmi A. Kondapalli and Teresa K. Woodruff; 3.2. Oviduct and uterus Leo F. Doherty and Hugh S. Taylor; 3.3. Breast Maricel V. Maffini, Carlos Sonnenschein and Ana M. Soto; 4. Development and maturation of the normal male reproductive system Richard M. Sharpe; 5. Modern genetics of reproductive biology Taisen Iguchi and Tamotsu Sudo; 6. Mechanisms of endocrine disruption K. Leigh Greathouse and Cheryl L. Walker; 7. Developmental exposures and implications for early and latent disease Retha R. Newbold and Jerrold J. Heindel; 8. Wildlife as sentinels of environmental impacts on reproductive health and fertility Heather J. Hamlin and Louis J. Guillette Jr; 9. Environmental contaminants and effects on timing and progression of human pubertal development Annette Mouritsen, Julie Damm, Lise Aksglaede, Kaspar Sørensen and Anders Juul; 10. Environmental contaminants and impacts on healthy and successful pregnancies Re;my Slama and Sylvaine Cordier; 11. Environmental contaminants and the reproductive and fertility effects in the male: 11.1. Introduction Sarah J. Janssen; 11.2. Environmental contaminants and male reproductive health: possible role of fetal exposure Jorma Toppari, Helena E. Virtanen and Niels E. Skakkebaek; 11.3. Environmental contaminants and male reproductive health: adult exposure and effects on fertility John D. Meeker and Russ Hauser; 12. Environmental contaminants, female reproductive health and fertility Pauline Mendola and Germaine M. Buck Louis; 13. Environmental contaminants and related systems that have implications for reproduction: 13.1. The neuroendocrine system Andrea C. Gore; 13.2. The thyroid system R. Thomas Zoeller and John D. Meeker; 13.3. The immune system Robert W. Luebke and Dori R. Germolec; 14. Environmental contaminants and cancers of the reproductive tract Gail S. Prins and Esther L. Calderon; 15. Communicating with patients and the public about environmental exposures and reproductive risk Gina M. Solomon and Sarah J. Janssen; 16. Interpreting science in the policy context Tracey J. Woodruff and Sarah J. Janssen; 17. Conclusions - what does all this mean and where are we going? Shanna H. Swan, Patricia Hunt and Linda C. Giudice; Index. |
| Altri titoli varianti | Environmental Impacts on Reproductive Health & Fertility |
| Record Nr. | UNINA-9910458997403321 |
| Cambridge : , : Cambridge University Press, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Environmental impacts on reproductive health and fertility / / edited by Tracey J. Woodruff [and three others] [[electronic resource]]
| Environmental impacts on reproductive health and fertility / / edited by Tracey J. Woodruff [and three others] [[electronic resource]] |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2010 |
| Descrizione fisica | 1 online resource (xi, 250 pages) : digital, PDF file(s) |
| Disciplina | 616.6/5071 |
| Collana | Cambridge medicine |
| Soggetto topico |
Reproductive toxicology
Reproductive health - Environmental aspects |
| ISBN |
1-107-20722-3
1-282-54698-8 9786612546983 0-511-67423-6 0-511-67542-9 0-511-67217-9 0-511-67089-3 0-511-67468-6 0-511-67344-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: 1. Introduction Tracey J. Woodruff and Linda C. Giudice; 2. Environmental contaminants and exposure Mary A. Fox and Yutaka Aoki; 3. Development and maturation of the normal female reproductive system: 3.1. Ovary Laxmi A. Kondapalli and Teresa K. Woodruff; 3.2. Oviduct and uterus Leo F. Doherty and Hugh S. Taylor; 3.3. Breast Maricel V. Maffini, Carlos Sonnenschein and Ana M. Soto; 4. Development and maturation of the normal male reproductive system Richard M. Sharpe; 5. Modern genetics of reproductive biology Taisen Iguchi and Tamotsu Sudo; 6. Mechanisms of endocrine disruption K. Leigh Greathouse and Cheryl L. Walker; 7. Developmental exposures and implications for early and latent disease Retha R. Newbold and Jerrold J. Heindel; 8. Wildlife as sentinels of environmental impacts on reproductive health and fertility Heather J. Hamlin and Louis J. Guillette Jr; 9. Environmental contaminants and effects on timing and progression of human pubertal development Annette Mouritsen, Julie Damm, Lise Aksglaede, Kaspar Sørensen and Anders Juul; 10. Environmental contaminants and impacts on healthy and successful pregnancies Re;my Slama and Sylvaine Cordier; 11. Environmental contaminants and the reproductive and fertility effects in the male: 11.1. Introduction Sarah J. Janssen; 11.2. Environmental contaminants and male reproductive health: possible role of fetal exposure Jorma Toppari, Helena E. Virtanen and Niels E. Skakkebaek; 11.3. Environmental contaminants and male reproductive health: adult exposure and effects on fertility John D. Meeker and Russ Hauser; 12. Environmental contaminants, female reproductive health and fertility Pauline Mendola and Germaine M. Buck Louis; 13. Environmental contaminants and related systems that have implications for reproduction: 13.1. The neuroendocrine system Andrea C. Gore; 13.2. The thyroid system R. Thomas Zoeller and John D. Meeker; 13.3. The immune system Robert W. Luebke and Dori R. Germolec; 14. Environmental contaminants and cancers of the reproductive tract Gail S. Prins and Esther L. Calderon; 15. Communicating with patients and the public about environmental exposures and reproductive risk Gina M. Solomon and Sarah J. Janssen; 16. Interpreting science in the policy context Tracey J. Woodruff and Sarah J. Janssen; 17. Conclusions - what does all this mean and where are we going? Shanna H. Swan, Patricia Hunt and Linda C. Giudice; Index. |
| Altri titoli varianti | Environmental Impacts on Reproductive Health & Fertility |
| Record Nr. | UNINA-9910792465903321 |
| Cambridge : , : Cambridge University Press, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Evaluating chemical and other agent exposures for reproductive and developmental toxicity [[electronic resource] /] / Subcommittee on Reproductive and Developmental Toxicology, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Evaluating chemical and other agent exposures for reproductive and developmental toxicity [[electronic resource] /] / Subcommittee on Reproductive and Developmental Toxicology, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2001 |
| Descrizione fisica | 1 online resource (262 p.) |
| Disciplina | 616.6/5071 |
| Collana | Compass series |
| Soggetto topico |
Reproductive toxicology
Developmental toxicology Toxicity testing |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-18509-0
9786610185092 0-309-56761-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Copyright""; ""Preface""; ""Contents""; ""Abbreviations""; ""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Summary""; ""CONCLUSIONS AND RECOMMENDATIONS""; ""Evaluative Process""; ""Assessing the Available Data""; ""Integration of Toxicity and Exposure Information""; ""Insufficient Data Sets""; ""Application of the Evaluative Process""; ""Sources of Information""; ""Research Recommendations""; ""1 Introduction ""; ""SUBCOMMITTEE'S TASK""
""ORGANIZATION OF THE REPORT""""2 The Evaluative Process: Part I. Assessing the Available Data ""; ""PRINCIPLES AND OBJECTIVES""; ""Use of Data and Judgment""; ""Weight of Evidence""; ""Threshold Assumption""; ""Narrative Statement""; ""Certainty""; ""Use All Relevant, Acceptable Data""; ""Qualities and Limitations of Reproductive and Developmental Toxicity Studies""; ""Characterizing Data""; ""Expert Review Team""; ""GENERAL DESCRIPTION""; ""DETAILS OF THE EVALUATIVE PROCESS""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Chemistry""; ""Basic Toxicity"" ""Acute Studies""""Repeated-Dose Studies""; ""Genetic Toxicity""; ""Pharmacokinetics""; ""Reproductive and Developmental Toxicity""; ""Human Data""; ""Weighing the Evidence""; ""Case Reports and Clinical Series""; ""Assessing Causality in Human Studies""; ""Experimental Animal Toxicity""; ""Utility and Limitations""; ""Adverse Effect""; ""3 The Evaluative Process: Part II. Integration of Toxicity and Exposure Information ""; ""INTERPRETATION OF TOXICITY DATA""; ""Default Assumptions To Be Considered in Assessing Reproductive and Developmental Toxicity Risk""; ""Absorption"" ""Cross-Species Extrapolation""""Exposure Duration""; ""Windows of Vulnerability""; ""Additivity""; ""QUANTITATIVE EVALUATION""; ""Identification of the NOAEL and LOAEL""; ""Calculation of the Benchmark Dose""; ""Duration Adjustment""; ""Uncertainty Factors""; ""Calculation of the Unlikely Effect Level""; ""Calculation of the Margin of Exposure (MOE)""; ""Assessing a Degree of Concern""; ""Application of Reproductive and Developmental Toxicity Data to Various Exposure Scenarios""; ""Critical Data Needs""; ""SUMMARY""; ""4 Incomplete or Insufficient Data Sets "" ""PRINCIPLES TO MINIMIZE RISK""""PRACTICAL APPLICATION""; ""REDUCING UNCERTAINTY""; ""5 Recommendations ""; ""GENERAL RECOMMENDATIONS""; ""RESEARCH RECOMMENDATIONS""; ""References""; ""Appendixes""; ""Appendix A Application of the Recommended Evaluative Process to Specific Chemicals ""; ""JP-8 JET FUEL""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Lethality""; ""Acute Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Repeated-Dose Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Cancer""; ""Genetic Toxicity"" ""Disposition and Pharmacokinetics"" |
| Record Nr. | UNINA-9910456042603321 |
| Washington, D.C., : National Academy Press, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Evaluating chemical and other agent exposures for reproductive and developmental toxicity [[electronic resource] /] / Subcommittee on Reproductive and Developmental Toxicology, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Evaluating chemical and other agent exposures for reproductive and developmental toxicity [[electronic resource] /] / Subcommittee on Reproductive and Developmental Toxicology, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2001 |
| Descrizione fisica | 1 online resource (262 p.) |
| Disciplina | 616.6/5071 |
| Collana | Compass series |
| Soggetto topico |
Reproductive toxicology
Developmental toxicology Toxicity testing |
| ISBN |
0-309-17139-3
1-280-18509-0 9786610185092 0-309-56761-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Copyright""; ""Preface""; ""Contents""; ""Abbreviations""; ""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Summary""; ""CONCLUSIONS AND RECOMMENDATIONS""; ""Evaluative Process""; ""Assessing the Available Data""; ""Integration of Toxicity and Exposure Information""; ""Insufficient Data Sets""; ""Application of the Evaluative Process""; ""Sources of Information""; ""Research Recommendations""; ""1 Introduction ""; ""SUBCOMMITTEE'S TASK""
""ORGANIZATION OF THE REPORT""""2 The Evaluative Process: Part I. Assessing the Available Data ""; ""PRINCIPLES AND OBJECTIVES""; ""Use of Data and Judgment""; ""Weight of Evidence""; ""Threshold Assumption""; ""Narrative Statement""; ""Certainty""; ""Use All Relevant, Acceptable Data""; ""Qualities and Limitations of Reproductive and Developmental Toxicity Studies""; ""Characterizing Data""; ""Expert Review Team""; ""GENERAL DESCRIPTION""; ""DETAILS OF THE EVALUATIVE PROCESS""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Chemistry""; ""Basic Toxicity"" ""Acute Studies""""Repeated-Dose Studies""; ""Genetic Toxicity""; ""Pharmacokinetics""; ""Reproductive and Developmental Toxicity""; ""Human Data""; ""Weighing the Evidence""; ""Case Reports and Clinical Series""; ""Assessing Causality in Human Studies""; ""Experimental Animal Toxicity""; ""Utility and Limitations""; ""Adverse Effect""; ""3 The Evaluative Process: Part II. Integration of Toxicity and Exposure Information ""; ""INTERPRETATION OF TOXICITY DATA""; ""Default Assumptions To Be Considered in Assessing Reproductive and Developmental Toxicity Risk""; ""Absorption"" ""Cross-Species Extrapolation""""Exposure Duration""; ""Windows of Vulnerability""; ""Additivity""; ""QUANTITATIVE EVALUATION""; ""Identification of the NOAEL and LOAEL""; ""Calculation of the Benchmark Dose""; ""Duration Adjustment""; ""Uncertainty Factors""; ""Calculation of the Unlikely Effect Level""; ""Calculation of the Margin of Exposure (MOE)""; ""Assessing a Degree of Concern""; ""Application of Reproductive and Developmental Toxicity Data to Various Exposure Scenarios""; ""Critical Data Needs""; ""SUMMARY""; ""4 Incomplete or Insufficient Data Sets "" ""PRINCIPLES TO MINIMIZE RISK""""PRACTICAL APPLICATION""; ""REDUCING UNCERTAINTY""; ""5 Recommendations ""; ""GENERAL RECOMMENDATIONS""; ""RESEARCH RECOMMENDATIONS""; ""References""; ""Appendixes""; ""Appendix A Application of the Recommended Evaluative Process to Specific Chemicals ""; ""JP-8 JET FUEL""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Lethality""; ""Acute Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Repeated-Dose Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Cancer""; ""Genetic Toxicity"" ""Disposition and Pharmacokinetics"" |
| Record Nr. | UNINA-9910778611203321 |
| Washington, D.C., : National Academy Press, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Evaluating chemical and other agent exposures for reproductive and developmental toxicity / / Subcommittee on Reproductive and Developmental Toxicology, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Evaluating chemical and other agent exposures for reproductive and developmental toxicity / / Subcommittee on Reproductive and Developmental Toxicology, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, c2001 |
| Descrizione fisica | 1 online resource (262 p.) |
| Disciplina | 616.6/5071 |
| Collana | Compass series |
| Soggetto topico |
Reproductive toxicology
Developmental toxicology Toxicity testing |
| ISBN |
9786610185092
9780309171397 0309171393 9781280185090 1280185090 9780309567619 0309567610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Copyright""; ""Preface""; ""Contents""; ""Abbreviations""; ""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Summary""; ""CONCLUSIONS AND RECOMMENDATIONS""; ""Evaluative Process""; ""Assessing the Available Data""; ""Integration of Toxicity and Exposure Information""; ""Insufficient Data Sets""; ""Application of the Evaluative Process""; ""Sources of Information""; ""Research Recommendations""; ""1 Introduction ""; ""SUBCOMMITTEE'S TASK""
""ORGANIZATION OF THE REPORT""""2 The Evaluative Process: Part I. Assessing the Available Data ""; ""PRINCIPLES AND OBJECTIVES""; ""Use of Data and Judgment""; ""Weight of Evidence""; ""Threshold Assumption""; ""Narrative Statement""; ""Certainty""; ""Use All Relevant, Acceptable Data""; ""Qualities and Limitations of Reproductive and Developmental Toxicity Studies""; ""Characterizing Data""; ""Expert Review Team""; ""GENERAL DESCRIPTION""; ""DETAILS OF THE EVALUATIVE PROCESS""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Chemistry""; ""Basic Toxicity"" ""Acute Studies""""Repeated-Dose Studies""; ""Genetic Toxicity""; ""Pharmacokinetics""; ""Reproductive and Developmental Toxicity""; ""Human Data""; ""Weighing the Evidence""; ""Case Reports and Clinical Series""; ""Assessing Causality in Human Studies""; ""Experimental Animal Toxicity""; ""Utility and Limitations""; ""Adverse Effect""; ""3 The Evaluative Process: Part II. Integration of Toxicity and Exposure Information ""; ""INTERPRETATION OF TOXICITY DATA""; ""Default Assumptions To Be Considered in Assessing Reproductive and Developmental Toxicity Risk""; ""Absorption"" ""Cross-Species Extrapolation""""Exposure Duration""; ""Windows of Vulnerability""; ""Additivity""; ""QUANTITATIVE EVALUATION""; ""Identification of the NOAEL and LOAEL""; ""Calculation of the Benchmark Dose""; ""Duration Adjustment""; ""Uncertainty Factors""; ""Calculation of the Unlikely Effect Level""; ""Calculation of the Margin of Exposure (MOE)""; ""Assessing a Degree of Concern""; ""Application of Reproductive and Developmental Toxicity Data to Various Exposure Scenarios""; ""Critical Data Needs""; ""SUMMARY""; ""4 Incomplete or Insufficient Data Sets "" ""PRINCIPLES TO MINIMIZE RISK""""PRACTICAL APPLICATION""; ""REDUCING UNCERTAINTY""; ""5 Recommendations ""; ""GENERAL RECOMMENDATIONS""; ""RESEARCH RECOMMENDATIONS""; ""References""; ""Appendixes""; ""Appendix A Application of the Recommended Evaluative Process to Specific Chemicals ""; ""JP-8 JET FUEL""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Lethality""; ""Acute Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Repeated-Dose Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Cancer""; ""Genetic Toxicity"" ""Disposition and Pharmacokinetics"" |
| Record Nr. | UNINA-9910960101203321 |
| Washington, D.C., : National Academy Press, c2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||