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70 Years of Levothyroxine / / edited by George J. Kahaly
| 70 Years of Levothyroxine / / edited by George J. Kahaly |
| Autore | Kahaly George J |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Springer Nature, 2021 |
| Descrizione fisica | 1 online resource (XVII, 129 p. 37 illus., 34 illus. in color.) |
| Disciplina |
616.4
615.36 |
| Soggetto topico |
Endocrinology
Pharmacology Endocrinology Pharmacology/Toxicology Hormones tiroides Medicaments Farmacologia Malalties de les glàndules endocrines |
| Soggetto genere / forma | Llibres electrònics |
| Soggetto non controllato |
Endocrinology
Pharmacology/Toxicology Pharmacology Thyroid gland Hypothyroidism TSH Thyroid disorders Metabolism Open Access |
| ISBN | 3-030-63277-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | History Of Levothyroxine -- Pharmacokinetics Of Levothyroxine -- Pharmacodynamics Of Levothyroxine -- Levothyroxine In Pregnancy -- Levothyroxine In Children -- Levothyroxine In The Elderly -- Levothyroxine And Heart -- Levothyroxine And Bone -- Levothyroxine And Cancer -- Potential Adverse Reactions Of Levothyroxine. |
| Record Nr. | UNINA-9910473450103321 |
Kahaly George J
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| Springer Nature, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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[9-11]: Malattie del sistema endocrino e del metabolismo : malattie endocrine, malattie del ricambio / Claudio Rugarli ... [et al.]
| [9-11]: Malattie del sistema endocrino e del metabolismo : malattie endocrine, malattie del ricambio / Claudio Rugarli ... [et al.] |
| Pubbl/distr/stampa | Milano, : Edra, 2016 |
| Descrizione fisica | XII, 1315-1586 p. : ill. ; 29 cm |
| Disciplina |
616(Malattie)
616.4(Endocrinologia) 572.84(Metabolismo) |
| ISBN | 978-88-214-4391-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNICAMPANIA-VAN00113454 |
| Milano, : Edra, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
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AACE clinical case reports
| AACE clinical case reports |
| Pubbl/distr/stampa | Jacksonville, FL : , : American Association of Clinical Endocrinologists, , [2015]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616.4 |
| Soggetto topico |
Endocrine System Diseases
Electronic journals |
| Soggetto genere / forma |
Case Reports.
Periodical Periodicals. |
| ISSN | 2376-0605 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
ACCR
American Association of Clinical Endocrinologists clinical case reports |
| Record Nr. | UNINA-9910367616503321 |
| Jacksonville, FL : , : American Association of Clinical Endocrinologists, , [2015]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AACE clinical case reports
| AACE clinical case reports |
| Pubbl/distr/stampa | Jacksonville, FL : , : American Association of Clinical Endocrinologists, , [2015]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616.4 |
| Soggetto topico |
Endocrine System Diseases
Electronic journals |
| Soggetto genere / forma |
Case Reports.
Periodical Periodicals. |
| ISSN | 2376-0605 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
ACCR
American Association of Clinical Endocrinologists clinical case reports |
| Record Nr. | UNISA-996411349203316 |
| Jacksonville, FL : , : American Association of Clinical Endocrinologists, , [2015]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Acromegaly : a guide to diagnosis and treatment / / Lewis S. Blevins, Manish K. Aghi, editors
| Acromegaly : a guide to diagnosis and treatment / / Lewis S. Blevins, Manish K. Aghi, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (300 pages) |
| Disciplina | 616.4 |
| Collana | Contemporary endocrinology |
| Soggetto topico |
Acromegaly
Acromegàlia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-031-16258-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Preface -- Contents -- Chapter 1: The Molecular Biology and Pathology of Acromegaly -- Introduction -- Physiological Features of GH and IGF1 -- GH Physiology -- IGF1 Physiology -- Pathogenesis of Somatotroph Adenomas -- Altered cAMP Signaling in Somatotroph Adenomas -- Epigenetic Gene Silencing in Somatotroph Adenomas -- Gene Overexpression in Somatotroph Adenomas -- The Impact of Histopathological Features in Somatotroph Adenoma Management -- Classification of Pituitary Adenomas -- Somatotroph Adenoma Behavior Based on Pathological Features -- Somatostatin Receptor Subtypes in Somatotroph Adenomas -- Densely Granulated Vs Sparsely Granulated Somatotroph Adenomas -- Dual-Staining Somatotroph Adenomas -- Conclusions -- References -- Chapter 2: Growth Hormone-Releasing Hormone-Secreting Neuroendocrine Tumors -- Introduction -- Causes of Ectopic GHRH Production -- Clinical Presentation of Ectopic GHRH Production -- Diagnostic Workup of Ectopic GHRH Syndrome -- Differential Diagnosis for NETs According to Site -- Treatment Options for NETs -- Prognosis -- References -- Chapter 3: Diagnosis of Acromegaly -- Introduction -- Physiology and Pathophysiology -- Clinical Evaluation -- Laboratory Testing -- Imaging Studies -- Approach to the Patient -- Summary and Future Directions -- References -- Chapter 4: Imaging in Acromegaly -- Anatomy -- Imaging of the Pituitary Gland -- Imaging of Tumors in the Gland -- Microadenoma (Fig. 4.2) -- Macroadenoma (Fig. 4.3) -- Mimics (Fig. 4.5) -- Systemic Findings of Acromegaly -- Advances in Imaging of the Pituitary Gland -- References -- Chapter 5: The Clinical Presentation of Acromegaly -- Background and Historical Perspective -- Signs and Symptoms Prompting Diagnosis -- Why Is There a Prolonged Delay in Diagnosis of Acromegaly, Given the Classic and Recognizable Clinical Features of this Disease?.
What Are the Signs, Symptoms, and/or Reasons That Ultimately Lead to the Diagnosis? -- What Signs and Symptoms Are Present at the Time of Diagnosis of Acromegaly? -- Severity of the Disease -- Diseases or Conditions with Clinical Overlap That May Mimic Acromegaly -- Conclusions -- References -- Chapter 6: Sleep-Disordered Breathing in Acromegaly -- Introduction -- Obstructive Sleep Apnea -- Definition and Diagnosis -- Epidemiology -- Symptoms and Risk Factors -- Complications of Untreated Obstructive Sleep Apnea -- Treatment of Obstructive Sleep Apnea -- Central Sleep Apnea -- Conclusion -- References -- Chapter 7: Cardiovascular Pathology in Acromegaly -- Background -- Pathogenesis -- Acromegalic Cardiomyopathy -- Hypertension -- Coronary Arterial Disease -- Arrythmias -- Valvular Heart Disease -- Diagnostic Evaluation -- HTN -- Cardiomyopathy -- Arrythmias -- Atherosclerotic Arterial Disease -- Treatment of Cardiovascular Complications in Acromegaly -- Transsphenoidal Surgery -- Somatostatin Analogs -- GHR Antagonists -- Summary -- References -- Chapter 8: Diabetes Mellitus in Acromegaly -- Epidemiology -- Pathogenesis of Diabetes in Acromegaly -- Excess Growth Hormone Leads to Increased Lipolysis -- Increased Free Fatty Acids Interfere with Insulin Signaling Pathway -- Increased Free Fatty Acids Promote Gluconeogenesis and Inhibit Glycolysis -- Increased Expression of Pro-inflammatory Adipokines and Cytokines -- β-Cell Dysfunction -- Treatment -- Choice of Therapy for Acromegaly -- Treatment of Diabetes in Patients with Acromegaly -- References -- Chapter 9: Musculoskeletal Disorders of Acromegaly -- References -- Chapter 10: Acromegaly and Cancer -- Acromegaly and Cancer Mortality -- Disease Control and Cancer Mortality -- Evidence for Involvement of the GH/IGF Axis in Cancer Development -- Height and Cancer. GH/IGF-1 and Cancer in General Populations -- GH/IGF Receptor Signaling in Cancer -- Cancer Incidence in Acromegaly -- Specific Cancer Incidence -- Colon Cancer and Acromegaly -- Thyroid Cancer and Acromegaly -- Breast Cancer and Acromegaly -- Prostate Cancer and Acromegaly -- Other Cancers and Acromegaly -- Summary of Cancer Incidence -- Diabetes and Cancer Incidence in Acromegaly -- Conclusion -- References -- Chapter 11: Mortality in Acromegaly -- Introduction -- GH and IGF-1 Levels as Predictors of Mortality -- Hypopituitarism and Mortality -- Radiotherapy and Mortality -- Cancer Incidence, Mortality, and Acromegaly -- Other Causes of Mortality -- Cardiovascular Disease -- Sleep Apnea -- Diabetes -- Conclusions -- References -- Chapter 12: An Overview of the Approach to the Management of Acromegaly -- References -- Chapter 13: Transsphenoidal Surgery for Acromegaly -- Introduction -- Diagnosis and Referral -- Preoperative Management -- Preoperative Imaging -- Premedication -- Operative Details: Transsphenoidal Surgery -- Technique -- Anesthetic Considerations -- Positioning -- Typical Surgical Steps -- Morbidity of Transsphenoidal Surgery for Acromegaly -- Vascular Complications -- CSF Leak -- Adenohypophysis Hormonal Deficits -- Diabetes Insipidus and SIADH -- Biochemical Outcomes and Management of Residual Tumor -- References -- Chapter 14: Stereotactic Radiosurgery and Radiation Therapy for Acromegaly -- Introduction -- Historical Perspective -- Stereotactic Radiosurgery for Acromegaly -- Patient Selection and Pre-SRS Evaluation -- SRS Procedure -- Endocrine Control -- Complications from SRS -- Repeated GKRS -- Brief Cessation of Antisecretory Medication around the Time of SRS -- Fractionated Radiation Therapy for Acromegaly -- Endocrine Control -- Complications Following FRT -- Proton Beam Irradiation -- Conclusions -- References -- Untitled. Chapter 15: Challenging Questions in the Management of Acromegaly in the Young -- Introduction -- Case Presentation -- Challenging Clinical Management Questions -- Conclusions -- References -- Chapter 16: Somatostatin Analogues in the Management of Patients with Acromegaly -- References -- Chapter 17: Use of Dopamine Agonists for Acromegaly -- History of Acromegaly Treatment and Use of Dopamine Agonists -- Mechanism of Action of Dopamine Agonists in Acromegaly -- Acromegaly Treatment Algorithm -- Dopamine Agonist Dosing in Acromegaly -- Dopamine Agonists as Monotherapy -- Dopamine Agonists as Combination Therapy -- Dopamine Agonists and Somatostatin Analogues -- Dopamine Agonists and Growth Hormone Receptor Antagonists -- Side Effects of Dopamine Agonists -- Summary -- References -- Chapter 18: Pegvisomant: Lessons Learned After 20 Years and Practical Recommendations of Its Use for the Treatment of Acromegaly -- Introduction -- Data from Clinical Studies of Pegvisomant -- When to Consider Pegvisomant Therapy in Patients with Acromegaly -- Initiation, Titration, and Maintenance of Pegvisomant Therapy -- Precautions When Using Pegvisomant -- Cost Considerations When Using Pegvisomant -- Conclusion -- References -- Chapter 19: Perspectives on Combination Medical Therapy in the Treatment of Acromegaly -- Introduction -- Somatostatin Receptor Ligand and Dopamine Agonist Combination Treatment -- Adverse Effects -- Somatostatin Receptor Ligand and Growth Hormone Receptor Antagonist Combined Treatment -- Long-Acting First-Generation Somatostatin Receptor Ligands and Pegvisomant (SRL-PEG) -- Primary Efficacy Endpoints -- Secondary Efficacy Endpoints -- Adverse Effects -- Pasireotide Long-Acting Release and Pegvisomant (PAS-PEG) -- Primary Efficacy Endpoints -- Secondary Efficacy Endpoints -- Adverse Effects -- Cabergoline and Pegvisomant Combination Treatment. Conclusion -- References -- Chapter 20: Long-Term Follow-up of Patients with Acromegaly -- References -- Chapter 21: Acromegaly from the Perspective of a Patient -- A Perspective -- The Diagnosis Story -- The Surgery and Treatment -- Pituitary World News -- The Work and the Learning Continues -- About Insights -- On Family and Genetics -- How Awareness Works: One Story -- References -- Index. |
| Record Nr. | UNINA-9910629290103321 |
| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Acromegaly : diagnosis & treatment / / editors, Ferdinand Roelfsema, Nienke R. Biermasz
| Acromegaly : diagnosis & treatment / / editors, Ferdinand Roelfsema, Nienke R. Biermasz |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London : , : Future Medicine Ltd., , [2012] |
| Descrizione fisica | 1 online resource (163 p.) |
| Disciplina | 616.4 |
| Soggetto topico |
Acromegaly - Diagnosis
Acromegaly - Treatment |
| ISBN | 1-78084-159-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title page; Copyright page; Contents; Foreword. Acromegaly: diagnosisand treatment; 1. History of acromegaly; 2. Pathology and pathogenesis of growth hormone-secreting pituitary adenomas; 3. Regulation of growth hormone secretion; 4. Clinical and laboratory diagnosis of acromegaly; 5. Goals of treatment; 6. Trans-sphenoidal surgery with the classical microscopical approach; 7. 3D endoscopic endonasal surgery for pituitary and skull base pathology; 8. Medical treatment of acromegaly; 9. Radiation techniques; 10. Quality of life in patients with acromegaly
11. Future perspectives of diagnosis and treatment of acromegalyIndex |
| Record Nr. | UNINA-9910787590703321 |
| London : , : Future Medicine Ltd., , [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Acromegaly : diagnosis & treatment / / editors, Ferdinand Roelfsema, Nienke R. Biermasz
| Acromegaly : diagnosis & treatment / / editors, Ferdinand Roelfsema, Nienke R. Biermasz |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London : , : Future Medicine Ltd., , [2012] |
| Descrizione fisica | 1 online resource (163 p.) |
| Disciplina | 616.4 |
| Soggetto topico |
Acromegaly - Diagnosis
Acromegaly - Treatment |
| ISBN | 1-78084-159-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Title page; Copyright page; Contents; Foreword. Acromegaly: diagnosisand treatment; 1. History of acromegaly; 2. Pathology and pathogenesis of growth hormone-secreting pituitary adenomas; 3. Regulation of growth hormone secretion; 4. Clinical and laboratory diagnosis of acromegaly; 5. Goals of treatment; 6. Trans-sphenoidal surgery with the classical microscopical approach; 7. 3D endoscopic endonasal surgery for pituitary and skull base pathology; 8. Medical treatment of acromegaly; 9. Radiation techniques; 10. Quality of life in patients with acromegaly
11. Future perspectives of diagnosis and treatment of acromegalyIndex |
| Record Nr. | UNINA-9910817772003321 |
| London : , : Future Medicine Ltd., , [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Acta diabetologica latina
| Acta diabetologica latina |
| Descrizione fisica | Trimestrale. |
| Disciplina | 616.4(Endocrinologia) |
| ISSN | 0001-5563 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | ita |
| Record Nr. | UNICAMPANIA-SUN0036614 |
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
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Acta diabetologica latina
| Acta diabetologica latina |
| Descrizione fisica | Trimestrale. |
| Disciplina | 616.4(Endocrinologia) |
| ISSN | 0001-5563 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | ita |
| Record Nr. | UNICAMPANIA-VAN0036614 |
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
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Acta endocrinologica
| Acta endocrinologica |
| Pubbl/distr/stampa | København, : Scandinavian University Press |
| Disciplina | 616.4 |
| ISSN | 0001-5598 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | dan |
| Record Nr. | UNINA-990008884480403321 |
| København, : Scandinavian University Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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