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Amyloid
| Amyloid |
| Pubbl/distr/stampa | Stony Brook, N.Y., : Parthenon Pub., 1994- |
| Disciplina | 616.3995 |
| Soggetto topico |
Amyloid
Amyloidosis |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 1744-2818 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996335541503316 |
| Stony Brook, N.Y., : Parthenon Pub., 1994- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Amyloid
| Amyloid |
| Pubbl/distr/stampa | Stony Brook, N.Y., : Parthenon Pub., 1994- |
| Disciplina | 616.3995 |
| Soggetto topico |
Amyloid
Amyloidosis |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 1744-2818 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910154541903321 |
| Stony Brook, N.Y., : Parthenon Pub., 1994- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amyloid diseases / / edited by Dmitry Kurouski
| Amyloid diseases / / edited by Dmitry Kurouski |
| Pubbl/distr/stampa | London, England : , : IntechOpen, , [2019] |
| Descrizione fisica | 1 online resource (242 pages) : illustrations |
| Disciplina | 616.3995 |
| Soggetto topico | Amyloidosis - Diagnosis |
| ISBN |
1-83881-132-X
1-78985-382-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910332355103321 |
| London, England : , : IntechOpen, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amyloidosis : an insight to disease of systems and novel therapies / / edited by Işıl Adadan Güvenç
| Amyloidosis : an insight to disease of systems and novel therapies / / edited by Işıl Adadan Güvenç |
| Autore | Adadan Gü il |
| Pubbl/distr/stampa | IntechOpen, 2011 |
| Descrizione fisica | 1 online resource (206 pages) |
| Disciplina | 616.3995 |
| Soggetto topico | Amyloidosis |
| Soggetto non controllato | Infectious & contagious diseases |
| ISBN | 953-51-6572-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Amyloidosis |
| Record Nr. | UNINA-9910138154703321 |
Adadan Gü il
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| IntechOpen, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amyloidosis : mechanisms and prospects for therapy / / edited by Svetlana Sarantseva
| Amyloidosis : mechanisms and prospects for therapy / / edited by Svetlana Sarantseva |
| Autore | Sarantseva Svetlana |
| Pubbl/distr/stampa | IntechOpen, 2011 |
| Descrizione fisica | 1 online resource (228 pages) |
| Disciplina | 616.3995 |
| Soggetto topico | Amyloidosis |
| Soggetto non controllato | Infectious & contagious diseases |
| ISBN | 953-51-6497-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Amyloidosis |
| Record Nr. | UNINA-9910138154503321 |
|
Sarantseva Svetlana
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| IntechOpen, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amyloidosis : History and Perspectives / / edited by Jonathan S. Harrison
| Amyloidosis : History and Perspectives / / edited by Jonathan S. Harrison |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2022 |
| Descrizione fisica | 1 online resource (118 pages) |
| Disciplina | 616.3995 |
| Soggetto topico | Amyloidosis |
| ISBN | 1-83969-298-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Amyloidosis |
| Record Nr. | UNINA-9910586658503321 |
| London : , : IntechOpen, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amyloidosis : History and Perspectives / / edited by Jonathan S. Harrison
| Amyloidosis : History and Perspectives / / edited by Jonathan S. Harrison |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2022 |
| Descrizione fisica | 1 online resource (xi, 118 pages) : illustrations |
| Disciplina | 616.3995 |
| Soggetto topico |
Diagnosis
Amyloidosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Amyloidosis |
| Record Nr. | UNINA-9910688239403321 |
| London : , : IntechOpen, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amyloidosis / / edited by Dali Feng
| Amyloidosis / / edited by Dali Feng |
| Pubbl/distr/stampa | Rijeka, Croatia : , : IntechOpen, , [2013] |
| Descrizione fisica | 1 online resource (250 pages) : illustrations |
| Disciplina | 616.3995 |
| Soggetto topico | Amyloidosis |
| ISBN | 953-51-7160-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910317737603321 |
| Rijeka, Croatia : , : IntechOpen, , [2013] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cardiac Amyloidosis : Diagnosis and Treatment
| Cardiac Amyloidosis : Diagnosis and Treatment |
| Autore | Emdin Michele |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (319 pages) |
| Disciplina | 616.3995 |
| Altri autori (Persone) |
VergaroGiuseppe
AimoAlberto FontanaMarianna |
| ISBN | 3-031-51757-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- 1: Tribute to Claudio Rapezzi -- References -- 2: Giampaolo Merlini and the Pavia School -- References -- 3: A Brief History of Amyloidosis -- 3.1 Characterization of the Structure and Biochemical Composition of Amyloid Deposits -- 3.2 Novel Diagnostic Techniques -- 3.3 Therapeutic Approaches -- 3.4 Conclusions -- References -- 4: Pathophysiology, Classification, and Epidemiology of Amyloidosis -- 4.1 Definition and Nomenclature -- 4.2 Amyloid Fibers -- 4.3 Pathophysiology of Organ Damage -- 4.4 Classification and Epidemiology -- 4.4.1 Acquired Forms -- 4.4.2 Forms of Amyloidosis Related to Gene Mutations -- 4.5 Prognostic Significance of Different Types of Amyloidosis -- 4.5.1 AL Amyloidosis -- 4.5.2 ATTR Amyloidosis -- 4.6 Conclusions -- References -- 5: Amyloid Light Chain (AL) Amyloidosis -- 5.1 Epidemiology and Risk Factors -- 5.2 Pathophysiology -- 5.3 Clinical Manifestations -- 5.4 Diagnosis -- 5.5 Prognosis -- 5.6 Conclusions -- References -- 6: Hereditary Transthyretin Amyloidosis -- 6.1 Epidemiology -- 6.2 Genetic Basis of ATTRv -- 6.3 The Amyloidogenic Cascade -- 6.4 Clinical Manifestations -- 6.4.1 Heart Involvement -- 6.4.2 PNS Involvement -- 6.5 Other Clinical Manifestations -- 6.6 Prognosis -- 6.7 Presymptomatic Genetic Testing and Monitoring of Carriers -- 6.8 Conclusions -- References -- 7: Wild-Type ATTR Amyloidosis -- 7.1 Definition and Epidemiology -- 7.2 Pathophysiology -- 7.2.1 Transthyretin -- 7.2.2 The TTR Amyloid Cascade -- 7.3 Clinical Manifestations -- 7.3.1 Cardiac Manifestations -- 7.3.1.1 Heart Failure -- 7.3.1.2 Aortic Stenosis -- 7.3.1.3 Arrhythmias -- 7.3.2 Extracardiac Manifestations -- References -- 8: Electrocardiographic Patterns -- 8.1 Relevance of ECG Patterns for Diagnosis and Risk Stratification.
8.2 ECG Patterns in AL Vs. ATTR Amyloidosis -- 8.3 Bradyarrhythmias and Tachyarrhythmias -- 8.3.1 Ventricular Arrhythmias -- 8.3.2 Atrial Arrhythmias -- 8.3.3 Bradyarrhythmias and Conduction Disturbances -- 8.4 Conclusions -- References -- 9: Echocardiography: A Gatekeeper to Diagnosis -- 9.1 M-mode Echocardiography -- 9.2 2D Echocardiography -- 9.3 Diastolic Function and Right Heart Involvement -- 9.4 Tissue Doppler Imaging -- 9.5 Speckle Tracking Echocardiography -- 9.6 Echocardiography for Differential Diagnosis Between Amyloidosis Subtypes -- 9.7 Echocardiography to Assess the Response to Treatment -- 9.8 Conclusions -- References -- 10: Cardiovascular Magnetic Resonance: Characterization of Myocardial Involvement -- 10.1 Introduction -- 10.2 Morphological and Functional Assessment -- 10.3 Strain -- 10.4 Diffusion Tensor Imaging -- 10.5 Late Gadolinium Enhancement -- 10.6 T1 Mapping -- 10.7 T2 Mapping -- 10.8 Perfusion -- 10.9 ECV Mapping -- 10.10 Extracardiac Findings -- 10.11 CMR for Prognostic Assessment -- 10.12 CMR for Disease Monitoring -- 10.13 Use of CMR: Current Recommendations by Scientific Societies -- 10.14 Conclusions -- References -- 11: Biomarkers: Monoclonal Protein and Indicators of Cardiac Damage -- 11.1 Amyloidogenic Precursors of AL Amyloidosis -- 11.2 Biomarkers of Cardiac Damage in Light Chain Amyloidosis -- 11.2.1 Screening and Diagnosis -- 11.2.2 Risk Stratification -- 11.2.3 Treatment Management -- 11.3 Biomarkers of Cardiac Damage in Transthyretin Amyloidosis -- 11.3.1 Screening and Diagnosis -- 11.3.2 Risk Stratification -- 11.3.3 Treatment Management -- 11.4 Conclusions and Future Perspectives -- References -- 12: Plasma Transthyretin and Its Ligands -- References -- 13: Cardiac Scintigraphy with Bone-Avid Tracers: Old and New Applications -- 13.1 Background. 13.2 Evolution of Cardiac Scintigraphy with Technetium-99m-Labeled Bone-Avid Radiotracers -- 13.3 Mechanism of Myocardial Uptake of Bone-Avid Tracers in ATTR-CA -- 13.4 Diagnostic Accuracy of 99mTc-PYP/DPD/HMDP for ATTR-CA -- 13.5 Diagnostic Criteria for ATTR-CA -- 13.6 Imaging Protocols for Tc-99m-PYP/DPD/HMDP Cardiac Scintigraphy -- 13.7 Current Applications of Bone Scintigraphy -- 13.7.1 Diagnosis of ATTR-CA in Patients with Heart Failure -- 13.7.2 Diagnosis of ATTR-CA in Patients with Heart Failure and Severe Aortic Valve Stenosis -- 13.7.3 Screening of At-Risk Patients for Early Detection of ATTR-CA: Carpal Tunnel Syndrome -- 13.7.4 Temporal Trends in Detection of ATTR-CA Due to Use of Bone-Avid Tracer Cardiac Scintigraphy -- 13.8 Novel Applications of Bone Scintigraphy: Assessment of Response to Therapy -- 13.9 Limitations -- 13.10 Conclusion/Summary -- References -- 14: PET-CT: A Tool for Etiological Diagnosis -- 14.1 PET Radiopharmaceuticals for Amyloid Detection -- 14.2 Conclusions -- References -- 15: The Role of Tissue Biopsy: Identification of the Amyloid Precursor and Beyond -- 15.1 Introduction -- 15.1.1 Tissue Analyses in Cardiac Amyloidosis -- 15.1.1.1 Histology -- 15.1.1.2 Histochemistry -- 15.1.1.3 Immunohistochemistry -- 15.1.2 Mass Spectrometry-Based Proteomics -- 15.2 Tissue Biopsy in Cardiac Amyloidosis -- 15.2.1 Endomyocardial Biopsy (EMB) -- 15.2.2 Surrogate Biopsy Sites -- 15.2.3 Other Biopsy Sites -- 15.3 Advantages and Limitations of Tissue Biopsy -- 15.4 Tissue Biopsy: Beyond the Diagnostic Purpose and Future Directions -- 15.5 Conclusions -- References -- 16: From Red Flags to Diagnosis -- 16.1 When Cardiac Amyloidosis Should Be Suspected -- 16.2 Diagnostic Algorithm -- 16.3 Different Approaches to the Suspicion and Diagnosis of CA -- 16.3.1 Red Flags -- 16.3.2 Diagnostic Algorithms. 16.3.3 Echocardiography -- 16.3.4 Biomarkers -- 16.3.5 Bone Scintigraphy -- 16.3.6 CMR -- 16.3.7 Tissue Biopsy -- 16.3.8 Genetic Testing -- 16.4 Conclusions -- References -- 17: Risk Prediction and Follow-Up -- 17.1 Follow-Up of Subjects at Risk of Developing CA -- 17.1.1 AL-CA -- 17.1.2 ATTR-CA -- 17.2 Risk Prediction in Patients Diagnosed with CA -- 17.3 Assessment of Treatment Response in Patients with CA -- 17.3.1 AL-CA -- 17.3.2 ATTR-CA -- 17.4 Conclusions -- References -- 18: Differential Diagnoses in Clinical Mimics -- 18.1 Hypertensive Heart Disease -- 18.2 Aortic Stenosis -- 18.3 Hypertrophic Cardiomyopathy (Sarcomeric and Phenocopies) -- 18.4 Cardiac Sarcoidosis -- 18.5 Haemochromatosis -- 18.6 Light-Chain Deposition Disease -- References -- 19: Applications of Artificial Intelligence in Amyloidosis -- 19.1 Artificial Intelligence and Machine Learning: Introduction and Use in Medicine -- 19.2 Artificial Intelligence and Cardiac Amyloidosis: Diagnosis -- 19.2.1 Clinical Variables and Biomarkers -- 19.2.2 Electrocardiogram -- 19.2.3 Echocardiography -- 19.2.4 Advanced Imaging Techniques (Cardiovascular Magnetic Resonance and PET) -- 19.3 Artificial Intelligence in Amyloidosis: Outcome -- 19.4 Machine Learning in Amyloidosis: Challenges and Future Perspectives -- 19.5 Conclusions -- References -- 20: Treatment of Amyloid Light-Chain Amyloidosis -- 20.1 General Principles of Treatment -- 20.2 General Assessment -- 20.3 Assessment of Response -- 20.4 Autologous Bone Marrow Transplantation -- 20.5 Therapy in Patients Not Candidates to Transplantation -- 20.6 Therapy of Relapsing or Non-responding Patients -- 20.7 Selective Anti-fibril Therapy -- 20.8 Conclusions -- References -- 21: Treatment of ATTR Amyloidosis: From Stabilizers to Gene Editing. 21.1 Understanding the Amyloidogenic Cascade to Develop Treatments -- 21.2 Imitating Nature with Selective TTR Stabilizers -- 21.2.1 Tafamidis -- 21.2.2 AG10 (Acoramidis) -- 21.3 Suppressing Protein Production with TTR Silencers -- 21.4 Small Interfering RNAs (siRNAs) -- 21.4.1 Patisiran -- 21.4.2 Revusiran -- 21.4.3 Vutrisiran -- 21.4.4 Antisense Oligonucleotides (ASOs) -- 21.4.5 Inotersen -- 21.4.6 Eplontersen -- 21.5 Editing the TTR Gene in Hepatocytes -- 21.5.1 NTLA-2001 -- 21.6 Conclusion -- References -- 22: Treatment of Cardiac Complications -- 22.1 Severe Aortic Stenosis -- 22.2 Atrial Fibrillation: Rhythm and Rate Control -- 22.3 Risk of Thromboembolic Events -- 22.4 Conduction Disturbances -- 22.5 Ventricular Arrhythmias and Dyssynchrony -- 22.6 Heart Failure -- 22.7 Orthostatic Hypotension -- 22.8 Conclusions -- References -- 23: Monitoring Disease Progression and Response to Disease-Modifying Treatments -- 23.1 Disease Monitoring in Transthyretin Cardiac Amyloidosis -- 23.2 Assessment of Treatment Response in Transthyretin Cardiac Amyloidosis -- 23.3 Disease Monitoring in Light-Chain Cardiac Amyloidosis -- 23.4 Perspectives -- 23.5 Conclusions -- References -- 24: Cardiac Amyloidosis: Open Issues and Future Perspectives -- 24.1 Mechanisms of Amyloid Formation and Tissue Infiltration -- 24.2 Towards a Completely Noninvasive Diagnostic Algorithm of Cardiac Amyloidosis -- 24.3 Open Issues in the Management of AL-CA -- 24.4 Impact of Earlier Diagnosis -- 24.5 Comparisons Between Different Gene Silencers and Gene Editing Therapies -- 24.6 Monitoring the Cardiac Response to Treatment -- 24.7 Long-Term Safety of TTR Depletion -- 24.8 Organization of Diagnosis, Management of Cardiac Amyloidosis, and Treatment Issues -- References. |
| Record Nr. | UNINA-9910847091803321 |
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Emdin Michele
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Chaperonopathies [[electronic resource] ] : Diseases with Defective Molecular Chaperones / / by Alberto J.L. Macario, Everly Conway de Macario, Francesco Cappello
| The Chaperonopathies [[electronic resource] ] : Diseases with Defective Molecular Chaperones / / by Alberto J.L. Macario, Everly Conway de Macario, Francesco Cappello |
| Autore | Macario Alberto J.L |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (116 p.) |
| Disciplina |
572.645
616.3995 |
| Collana | SpringerBriefs in Biochemistry and Molecular Biology |
| Soggetto topico |
Medicine
Biochemistry Proteins Biomedicine, general Biochemistry, general Protein Science |
| ISBN | 94-007-4667-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Overview and book plan -- Chaperones: General characteristics and classifications -- The chaperonopathies: classification, mechanisms, structural features -- Structural and hereditary chaperonopathies: mutation -- Other genetic chaperonopathies -- Acquired chaperonopathies -- Other types of chaperonopathies -- Impact of chaperonopathies in protein homeostasis and beyond -- Extracellular chaperones. |
| Record Nr. | UNINA-9910437620903321 |
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Macario Alberto J.L
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| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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