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Decoding the genomic control of immune reactions [[electronic resource]]
| Decoding the genomic control of immune reactions [[electronic resource]] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley, 2007 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 616.0796 |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Immunogenetics
Immunology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-34588-5
9786612345883 0-470-06212-6 0-470-06211-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Decoding the Genomic Control of Immune Reactions; Contents; Chair's introduction; Transcriptional regulatory networks in macrophages; DISCUSSION; The RIKEN mouse transcriptome: lessons learned and implications for the regulation of immune reactions; DISCUSSION; Molecular pathways for lymphangiogenesis and their role in human disease; DISCUSSION; GENERAL DISCUSSION I; Specifying the patterns of immune cell migration; DISCUSSION; Human monogenic disorders that confer predisposition to specific infections; DISCUSSION; The genetic control of susceptibility to Mycobacterium tuberculosis
DISCUSSIONTh2 lymphoproliferative disorders resulting from defective LAT signalosomes; DISCUSSION; Genetic analysis of systemic autoimmunity; DISCUSSION; Genetic resistance to smallpox: lessons from mousepox; DISCUSSION; The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes; DISCUSSION; Genetic control of host-pathogen interactions in mice; DISCUSSION; Mycobacterium tuberculosis and its ability to resist immunity; DISCUSSION; Systems genetics: the next generation in genetics research?; DISCUSSION Regulation of the immune system in metazoan parasite infectionsDISCUSSION; Closing remarks; Contributor Index; Subject Index |
| Record Nr. | UNINA-9910143587303321 |
| Chichester ; ; Hoboken, NJ, : Wiley, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Decoding the genomic control of immune reactions [[electronic resource]]
| Decoding the genomic control of immune reactions [[electronic resource]] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley, 2007 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 616.0796 |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Immunogenetics
Immunology |
| ISBN |
1-282-34588-5
9786612345883 0-470-06212-6 0-470-06211-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Decoding the Genomic Control of Immune Reactions; Contents; Chair's introduction; Transcriptional regulatory networks in macrophages; DISCUSSION; The RIKEN mouse transcriptome: lessons learned and implications for the regulation of immune reactions; DISCUSSION; Molecular pathways for lymphangiogenesis and their role in human disease; DISCUSSION; GENERAL DISCUSSION I; Specifying the patterns of immune cell migration; DISCUSSION; Human monogenic disorders that confer predisposition to specific infections; DISCUSSION; The genetic control of susceptibility to Mycobacterium tuberculosis
DISCUSSIONTh2 lymphoproliferative disorders resulting from defective LAT signalosomes; DISCUSSION; Genetic analysis of systemic autoimmunity; DISCUSSION; Genetic resistance to smallpox: lessons from mousepox; DISCUSSION; The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes; DISCUSSION; Genetic control of host-pathogen interactions in mice; DISCUSSION; Mycobacterium tuberculosis and its ability to resist immunity; DISCUSSION; Systems genetics: the next generation in genetics research?; DISCUSSION Regulation of the immune system in metazoan parasite infectionsDISCUSSION; Closing remarks; Contributor Index; Subject Index |
| Record Nr. | UNINA-9910829858503321 |
| Chichester ; ; Hoboken, NJ, : Wiley, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Decoding the genomic control of immune reactions
| Decoding the genomic control of immune reactions |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley, 2007 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 616.0796 |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Immunogenetics
Immunology |
| ISBN |
9786612345883
9781282345881 1282345885 9780470062128 0470062126 9780470062111 0470062118 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Decoding the Genomic Control of Immune Reactions; Contents; Chair's introduction; Transcriptional regulatory networks in macrophages; DISCUSSION; The RIKEN mouse transcriptome: lessons learned and implications for the regulation of immune reactions; DISCUSSION; Molecular pathways for lymphangiogenesis and their role in human disease; DISCUSSION; GENERAL DISCUSSION I; Specifying the patterns of immune cell migration; DISCUSSION; Human monogenic disorders that confer predisposition to specific infections; DISCUSSION; The genetic control of susceptibility to Mycobacterium tuberculosis
DISCUSSIONTh2 lymphoproliferative disorders resulting from defective LAT signalosomes; DISCUSSION; Genetic analysis of systemic autoimmunity; DISCUSSION; Genetic resistance to smallpox: lessons from mousepox; DISCUSSION; The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes; DISCUSSION; Genetic control of host-pathogen interactions in mice; DISCUSSION; Mycobacterium tuberculosis and its ability to resist immunity; DISCUSSION; Systems genetics: the next generation in genetics research?; DISCUSSION Regulation of the immune system in metazoan parasite infectionsDISCUSSION; Closing remarks; Contributor Index; Subject Index |
| Record Nr. | UNINA-9911019098803321 |
| Chichester ; ; Hoboken, NJ, : Wiley, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
DNA pharmaceuticals [[electronic resource] ] : formulation and delivery in gene therapy, DNA vaccination and immunotherapy / / edited by Martin Schleef
| DNA pharmaceuticals [[electronic resource] ] : formulation and delivery in gene therapy, DNA vaccination and immunotherapy / / edited by Martin Schleef |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2005 |
| Descrizione fisica | 1 online resource (277 p.) |
| Disciplina |
615.372
616.0796 |
| Altri autori (Persone) | SchleefM (Martin) |
| Soggetto topico |
DNA vaccines
Gene therapy Immunotherapy |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-85409-X
9786610854097 3-527-60753-6 3-527-60700-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
DNA Pharmaceuticals; Preface; Contents; List of Contributors; Abbreviations; 1 DNA Vaccines - An Overview; 1.1 Rationale for DNA Vaccines; 1.2 Preclinical Proof of Concept; 1.3 Clinical Trials; 1.4 Second-Generation Vaccines; 1.5 Conclusions; References; 2 DNA as a Pharmaceutical - Regulatory Aspects; 2.1 Introduction; 2.2 Quality Requirements for DNA used as a Gene Therapy Product; 2.2.1 Introduction; 2.2.2 Production and Purification; 2.2.2.1 Raw Materials; 2.2.2.2 Antibiotics; 2.2.2.3 Solvents; 2.2.2.4 Fermentation; 2.2.2.5 Purification; 2.2.3 Cell Banking System Procedures
2.2.3.1 Generation and Characterization of Master and Working Cell Banks2.2.4 Product Characterization and Quality Criteria; 2.2.4.1 Identity; 2.2.4.2 Purity; 2.2.4.3 Adventitious Agents; 2.2.4.4 Potency; 2.3 Safety Studies for Clinical Trials; 2.3.1 General Considerations; 2.3.2 Conduct of Preclinical Safety Studies; 2.3.2.1 Regulations; 2.3.2.2 Design of an Appropriate Toxicology Program; 2.3.2.3 Single- and Repeat-Dose Toxicity Studies; 2.3.2.4 Safety of the Formulated Plasmid DNA; 2.3.2.5 Specific Safety Considerations; 2.3.2.6 Choice of Animal Model; 2.4 Special Issues 2.4.1 Comparability of Plasmid Gene Therapy Products2.4.2 Mixed Plasmid Preparations; 2.4.3 Plasmid Molecular Structure; 2.5 Biosafety Issues and Environmental Risk Assessment; References; 3 From Bulk to Delivery: Plasmid Manufacturing and Storage; 3.1 Introduction; 3.1.1 Gene Therapy; 3.1.2 DNA Vaccination; 3.2 Manufacturing of Plasmid DNA; 3.2.1 Bacterial Cultivation; 3.2.2 Plasmid DNA Purification; 3.2.3 Innovative Aspects in Plasmid Manufacturing; 3.3 Quality Control of Plasmid DNA Vectors; 3.3.1 Proteins, Ribonucleic Acid, and Lipopolysaccharides; 3.3.2 Chromosomal DNA 3.3.3 Plasmid Identity3.3.4 Plasmid Topology (Structural Homogeneity); 3.4 Plasmid Stability during Storage and Application; 3.4.1 Long-Term Stability of Plasmid DNA; 3.4.2 Lyophilization for Long-Term Storage; 3.4.3 Stability during Application; 3.5 Future Developments; References; 4 Minimized, CpG-Depleted, and Methylated DNA Vectors: Towards Perfection in Nonviral Gene Therapy; 4.1 Introduction; 4.2 The Mammalian Immune System as a Barrier to Nonviral Gene Delivery; 4.3 Strategies to Minimize DNA Vectors 4.3.1 Excision of a DNA Fragment Containing a Transgene Expression Cassette from Plasmid DNA4.3.2 Intramolecular Site-Specific Recombination Within a Bacterial Plasmid; 4.3.3 Synthesis of Minimized DNA Vectors by PCR; 4.3.4 Improvement of Minimized DNA Vector Yield and Purity; 4.4 Depletion of CpG Dinucleotides in the Bacterial Vector Backbone; 4.5 Methylation of CpG Dinucleotides in Plasmid DNA; 4.6 Towards an Ideal Nonviral Vector; 4.7 Conclusion; References; 5 Localized Nucleic Acid Delivery: A Discussion of Selected Methods; 5.1 Foreword; 5.2 Nucleic Acid Delivery - What For? 5.3 Nucleic Acid Delivery - How? |
| Record Nr. | UNINA-9910144557003321 |
| Weinheim, : Wiley-VCH, c2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
DNA pharmaceuticals [[electronic resource] ] : formulation and delivery in gene therapy, DNA vaccination and immunotherapy / / edited by Martin Schleef
| DNA pharmaceuticals [[electronic resource] ] : formulation and delivery in gene therapy, DNA vaccination and immunotherapy / / edited by Martin Schleef |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2005 |
| Descrizione fisica | 1 online resource (277 p.) |
| Disciplina |
615.372
616.0796 |
| Altri autori (Persone) | SchleefM (Martin) |
| Soggetto topico |
DNA vaccines
Gene therapy Immunotherapy |
| ISBN |
1-280-85409-X
9786610854097 3-527-60753-6 3-527-60700-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
DNA Pharmaceuticals; Preface; Contents; List of Contributors; Abbreviations; 1 DNA Vaccines - An Overview; 1.1 Rationale for DNA Vaccines; 1.2 Preclinical Proof of Concept; 1.3 Clinical Trials; 1.4 Second-Generation Vaccines; 1.5 Conclusions; References; 2 DNA as a Pharmaceutical - Regulatory Aspects; 2.1 Introduction; 2.2 Quality Requirements for DNA used as a Gene Therapy Product; 2.2.1 Introduction; 2.2.2 Production and Purification; 2.2.2.1 Raw Materials; 2.2.2.2 Antibiotics; 2.2.2.3 Solvents; 2.2.2.4 Fermentation; 2.2.2.5 Purification; 2.2.3 Cell Banking System Procedures
2.2.3.1 Generation and Characterization of Master and Working Cell Banks2.2.4 Product Characterization and Quality Criteria; 2.2.4.1 Identity; 2.2.4.2 Purity; 2.2.4.3 Adventitious Agents; 2.2.4.4 Potency; 2.3 Safety Studies for Clinical Trials; 2.3.1 General Considerations; 2.3.2 Conduct of Preclinical Safety Studies; 2.3.2.1 Regulations; 2.3.2.2 Design of an Appropriate Toxicology Program; 2.3.2.3 Single- and Repeat-Dose Toxicity Studies; 2.3.2.4 Safety of the Formulated Plasmid DNA; 2.3.2.5 Specific Safety Considerations; 2.3.2.6 Choice of Animal Model; 2.4 Special Issues 2.4.1 Comparability of Plasmid Gene Therapy Products2.4.2 Mixed Plasmid Preparations; 2.4.3 Plasmid Molecular Structure; 2.5 Biosafety Issues and Environmental Risk Assessment; References; 3 From Bulk to Delivery: Plasmid Manufacturing and Storage; 3.1 Introduction; 3.1.1 Gene Therapy; 3.1.2 DNA Vaccination; 3.2 Manufacturing of Plasmid DNA; 3.2.1 Bacterial Cultivation; 3.2.2 Plasmid DNA Purification; 3.2.3 Innovative Aspects in Plasmid Manufacturing; 3.3 Quality Control of Plasmid DNA Vectors; 3.3.1 Proteins, Ribonucleic Acid, and Lipopolysaccharides; 3.3.2 Chromosomal DNA 3.3.3 Plasmid Identity3.3.4 Plasmid Topology (Structural Homogeneity); 3.4 Plasmid Stability during Storage and Application; 3.4.1 Long-Term Stability of Plasmid DNA; 3.4.2 Lyophilization for Long-Term Storage; 3.4.3 Stability during Application; 3.5 Future Developments; References; 4 Minimized, CpG-Depleted, and Methylated DNA Vectors: Towards Perfection in Nonviral Gene Therapy; 4.1 Introduction; 4.2 The Mammalian Immune System as a Barrier to Nonviral Gene Delivery; 4.3 Strategies to Minimize DNA Vectors 4.3.1 Excision of a DNA Fragment Containing a Transgene Expression Cassette from Plasmid DNA4.3.2 Intramolecular Site-Specific Recombination Within a Bacterial Plasmid; 4.3.3 Synthesis of Minimized DNA Vectors by PCR; 4.3.4 Improvement of Minimized DNA Vector Yield and Purity; 4.4 Depletion of CpG Dinucleotides in the Bacterial Vector Backbone; 4.5 Methylation of CpG Dinucleotides in Plasmid DNA; 4.6 Towards an Ideal Nonviral Vector; 4.7 Conclusion; References; 5 Localized Nucleic Acid Delivery: A Discussion of Selected Methods; 5.1 Foreword; 5.2 Nucleic Acid Delivery - What For? 5.3 Nucleic Acid Delivery - How? |
| Record Nr. | UNINA-9910829843803321 |
| Weinheim, : Wiley-VCH, c2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genetics of autoimmunity [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode]
| Genetics of autoimmunity [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005 |
| Descrizione fisica | 1 online resource (261 p.) |
| Disciplina |
616.0796
616.978 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Autoimmunity
Autoimmunity - Genetic aspects |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-23841-0
9786610238415 0-470-02139-X 0-470-02138-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GENETICS OF AUTOIMMUNITY; Contents; Participants; Chair's introduction; Patterns of genetic variation in humans and mice; Discussion; Haplotype tagging in pharmacogenetics; Discussion; Multiple sclerosis: a haplotype association study; Discussion; Mapping genes for asthma and psoriasis; Discussion; Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse; Discussion; The importance of epistatic interactions in the development of autoimmunity; Discussion; Mapping autoimmune disease genes in humans: lessons from IBD and SLE; Discussion
A combined genetics and genomics approach to unravelling molecular pathways in coeliac diseaseDiscussion; Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus; Discussion; A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling; Discussion; Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity; Discussion; An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells; Discussion; Large-scale screens for cDNAs with in vivo activity; Discussion Genomic mining of new genes and pathways in innate and adaptive immunityDiscussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910143740103321 |
| Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genetics of autoimmunity [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode]
| Genetics of autoimmunity [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005 |
| Descrizione fisica | 1 online resource (261 p.) |
| Disciplina |
616.0796
616.978 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Autoimmunity
Autoimmunity - Genetic aspects |
| ISBN |
1-280-23841-0
9786610238415 0-470-02139-X 0-470-02138-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GENETICS OF AUTOIMMUNITY; Contents; Participants; Chair's introduction; Patterns of genetic variation in humans and mice; Discussion; Haplotype tagging in pharmacogenetics; Discussion; Multiple sclerosis: a haplotype association study; Discussion; Mapping genes for asthma and psoriasis; Discussion; Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse; Discussion; The importance of epistatic interactions in the development of autoimmunity; Discussion; Mapping autoimmune disease genes in humans: lessons from IBD and SLE; Discussion
A combined genetics and genomics approach to unravelling molecular pathways in coeliac diseaseDiscussion; Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus; Discussion; A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling; Discussion; Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity; Discussion; An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells; Discussion; Large-scale screens for cDNAs with in vivo activity; Discussion Genomic mining of new genes and pathways in innate and adaptive immunityDiscussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910830610703321 |
| Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
HLA : immune response genetics
| HLA : immune response genetics |
| Pubbl/distr/stampa | [Hoboken, NJ] : , : John Wiley & Sons, , [2016]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616.0796 |
| Soggetto topico |
HLA histocompatibility antigens
Leucoagglutinins Leucocytes HLA Antigens Histocompatibility Antigens Immunity |
| Soggetto genere / forma |
Periodicals.
Fulltext Internet Resources. |
| ISSN | 2059-2310 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Immune response genetics
Human leukocyte antigens HLA, immune response genetics |
| Record Nr. | UNISA-996200349903316 |
| [Hoboken, NJ] : , : John Wiley & Sons, , [2016]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
HLA : immune response genetics
| HLA : immune response genetics |
| Pubbl/distr/stampa | [Hoboken, NJ] : , : John Wiley & Sons, , [2016]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616.0796 |
| Soggetto topico |
HLA histocompatibility antigens
Leucoagglutinins Leucocytes HLA Antigens Histocompatibility Antigens Immunity |
| Soggetto genere / forma |
Periodicals.
Fulltext Internet Resources. |
| ISSN | 2059-2310 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Immune response genetics
Human leukocyte antigens HLA, immune response genetics |
| Record Nr. | UNINA-9910170622003321 |
| [Hoboken, NJ] : , : John Wiley & Sons, , [2016]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunogenetics : Methods and Protocols / / edited by Anton W. Langerak
| Immunogenetics : Methods and Protocols / / edited by Anton W. Langerak |
| Autore | Langerak Anton W |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | New York, NY : , : Springer US : , : Imprint : Humana, , 2022 |
| Descrizione fisica | 1 online resource (XVI, 607 p. 132 illus., 121 illus. in color.) |
| Disciplina |
571.9648
616.0796 |
| Collana | Methods in Molecular Biology |
| Soggetto topico |
Immunogenetics
Immunospecificity Adaptive Immunity Immunogenètica Receptors cel·lulars Manuals de laboratori |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9781071621158
1071621157 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The Advent of Precision Immunology: Immunogenetics at the Center of Immune Cell Analysis in Health and Disease -- Next-Generation Sequencing-Based Clonality Detection of Immunoglobulin Gene Rearrangements in B-Cell Lymphoma -- One-Step Next Generation Sequencing of Immunoglobulin and T-Cell Receptor Gene Recombinations for MRD Marker Identification in Acute Lymphoblastic Leukemia -- Immunoglobulin/T-Cell Receptor Gene Rearrangement Analysis Using RNA-Seq -- Minimal Residual Disease Analysis by Monitoring Immunoglobulin and T-Cell Receptor Gene Rearrangements by Quantitative PCR and Droplet Digital PCR -- Quality Control for IG/TR Marker Identification and MRD Analysis -- cfDNA-Based NGS IG Analysis in Lymphoma -- Targeted Locus Amplification as Marker Screening Approach to Detect Immunoglobulin (IG) Translocations in B-Cell Non-Hodgkin Lymphomas -- Immunoglobulin/T-Cell Receptor Capture Strategy for Comprehensive Immunogenetics -- Immunoglobulin Gene Mutational Status Assessment by Next Generation Sequencing in Chronic Lymphocytic Leukemia -- NGS-Based B-Cell Receptor Repertoire Analysis in the Context of Inborn Errors of Immunity -- Generic Multiplex Digital PCR for Accurate Quantification of T-Cells in Copy Number Stable and Unstable DNA Samples -- Gene Engineering T-Cells with T-Cell Receptor for Adoptive Therapy -- Combined Analysis of Transcriptome and T-Cell Receptor Alpha Beta (TRA/TRB) Repertoire in Paucicellular Samples at the Single Cell Level -- AIRR Community Guide to Planning and Performing AIRR-Seq Experiments -- Adaptive Immune Receptor Repertoires (AIRR) Community Guide to TR and IG Gene Annotation -- Adaptive Immune Receptor Repertoires (AIRR) Community Guide to Repertoire Analysis -- Bulk gDNA Sequencing of Antibody Heavy Chain Gene Rearrangements for Detection and Analysis of B-Cell Clone Distribution: A Method by the AIRR Community -- Bulk Sequencing from mRNA with UMI for Evaluation of B-Cell Isotype and Clonal Evolution: A Method by the AIRR Community -- Single Cell Analysis and Tracking of Antigen-Specific T-Cells: Integrating Paired-Chain AIRR-Seq and Transcriptome Sequencing: A Method by the AIRR Community -- Quality Control: Chain Pairing Precision and Monitoring of Cross-Sample Contamination: A Method by the AIRR Community -- Immune Repertoire Analysis on High-Performance Computing Using VDJServer V1: A Method by the AIRR Community -- Data Sharing and Re-Use: A Method by the AIRR Community -- IMGT® Immunoinformatics Tools for Standardized V-DOMAIN Analysis -- IMGT/3Dstructure-DB: T-Cell Receptor TR Paratope and Peptide/Major Histocompatibility pMH Contact Sites and Epitope -- ARResT/Interrogate Immunoprofiling Platform: Concepts, Workflows, and Insights -- Purpose-Built Immunoinformatics for BcR IG/TR Repertoire Data Analysis. |
| Record Nr. | UNINA-9910576888603321 |
Langerak Anton W
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| New York, NY : , : Springer US : , : Imprint : Humana, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
