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Computational immunology : applications / / Shyamasree Ghosh
| Computational immunology : applications / / Shyamasree Ghosh |
| Autore | Ghosh Shyamasree |
| Pubbl/distr/stampa | Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020] |
| Descrizione fisica | 1 online resource (201 pages) |
| Disciplina | 616.0790285 |
| Soggetto topico | Immunoinformatics |
| ISBN |
1-351-02348-9
1-351-02349-7 1-351-02350-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910793933003321 |
Ghosh Shyamasree
|
||
| Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational immunology : applications / / Shyamasree Ghosh
| Computational immunology : applications / / Shyamasree Ghosh |
| Autore | Ghosh Shyamasree |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020] |
| Descrizione fisica | 1 online resource (201 pages) |
| Disciplina | 616.0790285 |
| Soggetto topico | Immunoinformatics |
| ISBN |
1-351-02348-9
1-351-02349-7 1-351-02350-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface -- Acknowledgments -- Author -- List of Abbreviations -- Introduction -- Chapter 1: Understanding Cell Fate and Computational Immunology -- 1.1 Introduction -- 1.2 Cell Fate -- 1.3 Computation and Stem Cell Biology and Cell Fate -- 1.4 Cell Cycle and Microenvironment in Cell Fate Determination -- 1.5 T and B Cell Fate Determination -- 1.5.1 T Cell Fate -- 1.5.2 B Cell Fate -- 1.6 Computational Prediction of Stem Cell Fates -- 1.7 Statistical Analysis and Application in Understanding of Stem Cell Fate -- 1.8 Deterministic and Stochastic Models of Cell Fate Choice -- 1.9 Decision Making and Disease -- 1.10 Statistical Analyses and Gene Regulatory Networks (GRNs) -- 1.10.1 Principal Components Analysis (PCA) -- 1.10.2 Partial Least Squares (PLS) Regression and GRNs -- 1.11 Discussions -- References -- Chapter 2: Next Generation Sequencing (NGS) and Computational Immunology -- 2.1 Introduction -- 2.2 NGS: A Glimpse through Available Technologies -- 2.3 NGS: Applications of Different Tools and Techniques -- 2.4 NGS and Tools of Data Analysis -- 2.5 NGS Applications -- 2.5.1 Applications in the Immune System -- 2.5.1.1 NGS in TCR Studies -- 2.5.1.2 NGS in BCR Studies -- 2.5.2 Cancer -- 2.5.3 NGS and Microbial Application -- 2.5.4 Infectious Diseases -- 2.5.5 NGS and Transplantation -- 2.5.6 Systemic Autoimmune Diseases -- 2.6 Single Cell Transcriptomics -- 2.7 ImmuneDB -- 2.8 ASAP-A Webserver for Immunoglobulin-Sequencing Analysis Pipeline -- 2.9 Discussions -- References -- Chapter 3: Computational Modeling and Biology of Disease -- 3.1 Introduction -- 3.2 Computation and Biology of Disease -- 3.2.1 Neurological Disorders -- 3.2.2 Respiratory Disorders -- 3.2.3 Cardiovascular Disorders -- 3.2.4 Diseases of the Bone -- 3.2.5 Kidney Diseases -- 3.2.6 Cancer.
3.2.7 Immunological Disorders -- 3.2.8 Infectious Diseases -- 3.2.9 Metabolic Disorder -- 3.2.9.1 Databases -- 3.2.9.2 Human Microbiome and Computational Methods -- 3.3 Discussion -- References -- Chapter 4: Drug Designing and Computational Immunology -- 4.1 Introduction -- 4.2 Computer-Aided Drug Designing (CADD) -- 4.3 Structure-Based Computer-Aided Drug Design (SB-CADD) -- 4.4 Polypharmocology -- 4.5 Adverse Drug Reactions -- 4.6 Retrobiosynthesis -- 4.7 Applications in Diseases -- 4.7.1 Neurological Diseases -- 4.7.2 Targeting Biomolecules and Channelopathies -- 4.7.3 Targeting P450 -- 4.7.4 Nanoparticle Drug Delivery Devices -- 4.7.5 Cancer -- 4.7.6 Cardiovascular -- 4.7.7 Antimicrobials -- 4.7.8 Drug Design and Immune System -- 4.7.9 Diabetes -- 4.7.10 Infectious Diseases -- 4.7.10.1 Influenza -- 4.7.10.2 Human Trypanosomiasis -- 4.7.10.3 HIV -- 4.7.10.4 Malaria -- 4.8 Small Molecules -- 4.9 Pocket-Based Drug Design -- 4.10 Drug Repositioning -- 4.11 Natural Compounds -- 4.12 Vaccination -- 4.13 Ligand-Based CADD (LB-CADD) -- 4.14 Discussion -- References -- Chapter 5: Computation and Identification of Biomarkers -- 5.1 Introduction -- 5.2 Biomarkers -- 5.3 Different Approaches to Biomarker Discovery -- 5.4 Computation and Identification of Biomarkers in Health -- 5.5 Computation and Identification of Biomarkers in Disease -- 5.5.1 Cancer -- 5.5.2 Inflammation Disorders -- 5.5.3 Inflammatory Bowel Disease (IBD) -- 5.5.4 HIV -- 5.5.5 Cardiovascular -- 5.5.6 Neurological -- 5.6 Discussion: Biomarkers in Detection of Clinical Outcomes -- References -- Chapter 6: Applications in Organ Transplantation -- 6.1 Introduction -- 6.2 Global Knowledge Base on Transplantation -- 6.3 Computer Simulations and Applications in Transplantation -- 6.4 Cardiac Transplants -- 6.5 Liver Transplantation -- 6.6 Kidney Transplantation -- 6.7 Lung Transplantation. 6.8 Others -- 6.9 Immunosuppression -- 6.10 Discussion -- References -- Chapter 7: Application in Disease Detection and Therapy -- 7.1 Introduction -- 7.2 Computation and Disease Detection and Monitoring -- 7.3 Cancer -- 7.4 Surgery -- 7.5 Brain Disorders -- 7.6 Cardiac Disorders -- 7.7 Studies in Animal Models -- 7.7.1 Neural Disorders -- 7.7.2 Therapy Outcome in HIV -- 7.7.3 Asthma -- 7.7.4 Antibiotic Research -- 7.7.5 Immunization -- 7.8 Discussion -- References -- Chapter 8: Computational Methods and Applications in Understanding of the Invertebrate Immune System -- 8.1 Introduction -- 8.1.1 Immune Cells and Systems and Pathways in Different Organisms in the Invertebrate Phyla -- 8.1.1.1 Immune System in Sponges -- 8.1.1.2 Cnidaria -- 8.1.1.3 Platyhelminthes -- 8.1.1.4 Nematodes -- 8.1.1.5 Annelida -- 8.1.1.6 Arthropoda -- 8.1.1.7 Mollusca -- 8.1.2 Regeneration in Planaria -- 8.1.3 Invertebrate Immunity and Database -- 8.2 Discussion -- References -- Chapter 9: Computational Immunology and Studies from the Human Immune System -- 9.1 Introduction -- 9.2 Infectious Disease -- 9.3 Modeling of H. pylori Infection Responses -- 9.4 Computational Immunology and Immune Responses -- 9.5 Computational Immunology and Insights into Macrophage Function -- 9.6 Discussion -- References -- Further Reading -- Glossary -- Index. |
| Record Nr. | UNINA-9910969754203321 |
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Ghosh Shyamasree
|
||
| Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others]
| Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others] |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2016 |
| Descrizione fisica | 1 online resource (212 p.) |
| Disciplina | 616.0790285 |
| Soggetto topico | Immunoinformatics |
| ISBN | 0-12-803715-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910797613003321 |
| Amsterdam, [Netherlands] : , : Academic Press, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others]
| Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others] |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2016 |
| Descrizione fisica | 1 online resource (212 p.) |
| Disciplina | 616.0790285 |
| Soggetto topico | Immunoinformatics |
| ISBN | 0-12-803715-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910809351003321 |
| Amsterdam, [Netherlands] : , : Academic Press, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
| Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of |
| Autore | Castiglione Filippo <1969, > |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , [2015] |
| Descrizione fisica | 1 online resource (284 p.) |
| Disciplina |
616.07/90285
616.0790285 |
| Soggetto topico |
Immunoinformatics
Immunology - Computer simulation Research Computer simulation Digital computer simulation |
| ISBN | 0-429-16951-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Preface; Acknowledgments; Contents; 1: Immunology for Aliens; 2: Aliens for Immunology; 3: C-ImmSim Unveiled; 4: Benchmarks, aka Qualitative Model Validation; 5: Specific Applications; 6: One Last Word; 7: Bibliography; Colour Plate Section |
| Record Nr. | UNINA-9910788023303321 |
|
Castiglione Filippo <1969, >
|
||
| Boca Raton : , : CRC Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
| Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of |
| Autore | Castiglione Filippo <1969, > |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , [2015] |
| Descrizione fisica | 1 online resource (284 p.) |
| Disciplina |
616.07/90285
616.0790285 |
| Soggetto topico |
Immunoinformatics
Immunology - Computer simulation Research Computer simulation Digital computer simulation |
| ISBN | 0-429-16951-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Preface; Acknowledgments; Contents; 1: Immunology for Aliens; 2: Aliens for Immunology; 3: C-ImmSim Unveiled; 4: Benchmarks, aka Qualitative Model Validation; 5: Specific Applications; 6: One Last Word; 7: Bibliography; Colour Plate Section |
| Record Nr. | UNINA-9910800192103321 |
|
Castiglione Filippo <1969, >
|
||
| Boca Raton : , : CRC Press, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Single Cell Sequencing and Systems Immunology / / edited by Xiangdong Wang
| Single Cell Sequencing and Systems Immunology / / edited by Xiangdong Wang |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (184 p.) |
| Disciplina | 616.0790285 |
| Collana | Translational Bioinformatics |
| Soggetto topico |
Immunology
Systems biology Proteomics Cytology Systems Biology Cell Biology |
| ISBN | 94-017-9753-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Significance of Single Cell Sequencing in Future Medicine -- Uncovering Phenotypes with Supercells: Applications to Single-Cell Sequencing -- Single-Cell Sequencing of Microorganisms -- Application of single-cell sequencing in dynamic transcriptomes -- System Immunology in Metabolic Research of Dendritic Cells -- FOXP3+ Treg Cells and Systems Biology Approaches to Studying Their Function -- γδT Cells and αβT Cells -- Prolymphocyte: Lymphocytes and Bioinformatics -- Lymphocytes in liver cancer -- Early biomarkers of hepatocyte necrosis -- Protocol of Single Cell Isolation by Flow Cytometry -- Single-cell based omics-the new era of human disease and medicine -- Cancer bioinformatics. . |
| Record Nr. | UNINA-9910298277503321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||