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The chemistry of molecular imaging / / edited by Nicholas Long, Wing-Tak Wong
| The chemistry of molecular imaging / / edited by Nicholas Long, Wing-Tak Wong |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , [2015] |
| Descrizione fisica | 1 online resource (434 p.) |
| Disciplina |
616.07
616.07540154 |
| Soggetto topico |
Imaging systems
Imaging systems in medicine Molecular probes |
| ISBN |
1-118-85481-0
1-118-85475-6 1-118-85477-2 |
| Classificazione | TEC015000 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Chemistry of Molecular Imaging; Copyright; Contents; Preface; List of Contributors; Chapter 1 An Introduction to Molecular Imaging; 1.1 Introduction; 1.2 What is Positron Emission Tomography (PET)?; 1.2.1 Basic Principles; 1.2.2 Advantages and Limitations; 1.3 What is Single Photon Emission Computed Tomography (SPECT)?; 1.3.1 Basic Principles; 1.3.2 Advantages and Limitations; 1.4 What is Computed Tomography (CT) or Computed Axial Tomography (CAT)?; 1.4.1 Basic Principles; 1.4.2 Advantages and Limitations; 1.5 What is Magnetic Resonance Imaging (MRI)?; 1.5.1 Basic Principles
1.5.2 Advantages and Limitations1.6 What is Optical Imaging?; 1.6.1 Basic Principles; 1.6.2 Conventional or Wide-Field Fluorescence Microscopy; 1.6.3 Confocal Microscopy or Confocal Laser Scanning Microscopy; 1.6.4 Advantages and Limitations; 1.7 What is Ultrasound (US)?; 1.7.1 Basic Principles; 1.7.2 Advantages and Limitations; 1.8 Conclusions; References; Chapter 2 Chemical Methodology for Labelling and Bioconjugation; 2.1 Introduction; 2.2 Chemical Methods; 2.2.1 Through Reactions with Aldehydes or Ketones; 2.2.2 Through Reactions with Azides; 2.2.3 Through Reactions with Alkenes 2.2.4 Cross-Coupling Reactions2.3 Site-Specific Modification of Proteins or Peptides; 2.3.1 N-terminal Cysteine; 2.3.2 Aromatic Residues; 2.3.3 N-terminus of Protein; 2.3.4 C-terminus of Protein; 2.3.5 Introduction of Chemical Tags for Site-Specific Labelling on Peptides or Proteins; 2.4 Conclusions; References; Chapter 3 Recent Developments in the Chemistry of [18F]Fluoride for PET; 3.1 Introduction; 3.2 Fluorine-18: The Starting Material; 3.3 Reactive [18F]Fluoride; 3.4 The Radiofluorination; 3.4.1 Electrophilic Reactions; 3.4.2 Nucleophilic Reactions 3.5 Labelling of Large Biological Molecules3.5.1 The Prosthetic Group Concept; 3.5.2 Prosthetic Entities with Fluorine-18 Bound to Aluminium, Boron, or Silicon; 3.5.3 Click Chemistry; 3.6 Conclusions; References; Chapter 4 Carbon-11, Nitrogen-13, and Oxygen-15 Chemistry: An Introduction to Chemistry with Short-Lived Radioisotopes; 4.1 Introduction; 4.2 Carbon-11 Chemistry; 4.2.1 Synthesis with [11C]Carbon Dioxide; 4.2.2 [11C]methylation Reactions; 4.2.3 [11C]Phosgene Reactions; 4.2.4 [11C]Cyanation Reactions; 4.2.5 [11C]Carbonylation Reactions; 4.3 Nitrogen-13 Chemistry 4.3.1 Synthesis of 13N-labelled Amines4.3.2 Enzymatic Synthesis of 13N-labelled Amino Acid; 4.3.3 Synthesis of [13N]cisplatin; 4.3.4 Synthesis of [13N] Carbamates and Ureas; 4.3.5 Other 13N-labelling Reactions; 4.4 Oxygen-15 Chemistry; 4.5 Conclusions; References; Chapter 5 The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I); 5.1 Introduction: Inorganic Nuclide-Based Radiopharmaceuticals; 5.2 Radiopharmaceutical Design; 5.3 Radiopharmaceutical Stability; 5.4 86Yttrium Radiometal Ion Properties; 5.4.1 Clinical Trials Based on 86Yttrium; 5.4.2 Recent 86Yttrium Work 5.4.3 Stability of 86Yttrium-Based Radiopharmaceuticals |
| Record Nr. | UNINA-9910140484103321 |
| Hoboken, New Jersey : , : Wiley, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The chemistry of molecular imaging / / edited by Nicholas Long, Wing-Tak Wong
| The chemistry of molecular imaging / / edited by Nicholas Long, Wing-Tak Wong |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , [2015] |
| Descrizione fisica | 1 online resource (434 p.) |
| Disciplina |
616.07
616.07540154 |
| Soggetto topico |
Imaging systems
Imaging systems in medicine Molecular probes |
| ISBN |
1-118-85481-0
1-118-85475-6 1-118-85477-2 |
| Classificazione | TEC015000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Chemistry of Molecular Imaging; Copyright; Contents; Preface; List of Contributors; Chapter 1 An Introduction to Molecular Imaging; 1.1 Introduction; 1.2 What is Positron Emission Tomography (PET)?; 1.2.1 Basic Principles; 1.2.2 Advantages and Limitations; 1.3 What is Single Photon Emission Computed Tomography (SPECT)?; 1.3.1 Basic Principles; 1.3.2 Advantages and Limitations; 1.4 What is Computed Tomography (CT) or Computed Axial Tomography (CAT)?; 1.4.1 Basic Principles; 1.4.2 Advantages and Limitations; 1.5 What is Magnetic Resonance Imaging (MRI)?; 1.5.1 Basic Principles
1.5.2 Advantages and Limitations1.6 What is Optical Imaging?; 1.6.1 Basic Principles; 1.6.2 Conventional or Wide-Field Fluorescence Microscopy; 1.6.3 Confocal Microscopy or Confocal Laser Scanning Microscopy; 1.6.4 Advantages and Limitations; 1.7 What is Ultrasound (US)?; 1.7.1 Basic Principles; 1.7.2 Advantages and Limitations; 1.8 Conclusions; References; Chapter 2 Chemical Methodology for Labelling and Bioconjugation; 2.1 Introduction; 2.2 Chemical Methods; 2.2.1 Through Reactions with Aldehydes or Ketones; 2.2.2 Through Reactions with Azides; 2.2.3 Through Reactions with Alkenes 2.2.4 Cross-Coupling Reactions2.3 Site-Specific Modification of Proteins or Peptides; 2.3.1 N-terminal Cysteine; 2.3.2 Aromatic Residues; 2.3.3 N-terminus of Protein; 2.3.4 C-terminus of Protein; 2.3.5 Introduction of Chemical Tags for Site-Specific Labelling on Peptides or Proteins; 2.4 Conclusions; References; Chapter 3 Recent Developments in the Chemistry of [18F]Fluoride for PET; 3.1 Introduction; 3.2 Fluorine-18: The Starting Material; 3.3 Reactive [18F]Fluoride; 3.4 The Radiofluorination; 3.4.1 Electrophilic Reactions; 3.4.2 Nucleophilic Reactions 3.5 Labelling of Large Biological Molecules3.5.1 The Prosthetic Group Concept; 3.5.2 Prosthetic Entities with Fluorine-18 Bound to Aluminium, Boron, or Silicon; 3.5.3 Click Chemistry; 3.6 Conclusions; References; Chapter 4 Carbon-11, Nitrogen-13, and Oxygen-15 Chemistry: An Introduction to Chemistry with Short-Lived Radioisotopes; 4.1 Introduction; 4.2 Carbon-11 Chemistry; 4.2.1 Synthesis with [11C]Carbon Dioxide; 4.2.2 [11C]methylation Reactions; 4.2.3 [11C]Phosgene Reactions; 4.2.4 [11C]Cyanation Reactions; 4.2.5 [11C]Carbonylation Reactions; 4.3 Nitrogen-13 Chemistry 4.3.1 Synthesis of 13N-labelled Amines4.3.2 Enzymatic Synthesis of 13N-labelled Amino Acid; 4.3.3 Synthesis of [13N]cisplatin; 4.3.4 Synthesis of [13N] Carbamates and Ureas; 4.3.5 Other 13N-labelling Reactions; 4.4 Oxygen-15 Chemistry; 4.5 Conclusions; References; Chapter 5 The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I); 5.1 Introduction: Inorganic Nuclide-Based Radiopharmaceuticals; 5.2 Radiopharmaceutical Design; 5.3 Radiopharmaceutical Stability; 5.4 86Yttrium Radiometal Ion Properties; 5.4.1 Clinical Trials Based on 86Yttrium; 5.4.2 Recent 86Yttrium Work 5.4.3 Stability of 86Yttrium-Based Radiopharmaceuticals |
| Record Nr. | UNINA-9910830411703321 |
| Hoboken, New Jersey : , : Wiley, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||