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Comparative immunoglobulin genetics / / edited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario Canada
| Comparative immunoglobulin genetics / / edited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario Canada |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Waretown, N.J. : , : Apple Academic Press, Inc., , [2014] |
| Descrizione fisica | 1 online resource (258 p.) |
| Disciplina | 616.07/98 |
| Soggetto topico |
Immunoglobulins - Genetics
Immunoglobulin genes |
| ISBN |
1-77463-334-5
0-429-15995-1 1-4822-4355-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; About The Editors; Contents; List Of Contributors; List Of Abbreviations; Preface; Chapter 1 Variable Lymphocyte Receptor-based Adaptive Immunity In The Agnathan Sea Lamprey; Chapter 2 Agnathan Sea Lamprey Tetrapods; Chapter 3 The Immunoglobulin Genes Of Bats; Chapter 4 Marsupial And Monotreme Immunoglobulin Genetics; Chapter 5 Organization Of The Immunoglobulin Heavy- And Light-chain Loci In The Rat; Chapter 6 Generation Of The Antibody Repertoire In Rabbits: Role Of Gut-associated Lymphoid Tissues; Chapter 7 The Immunoglobulin Genes Of Domestic Swine
Chapter 8 Bovine Immunoglobulin Genetics: Novel Phylogenetic PerspectiveChapter 9 Informatic Tools For Immunoglobulin Gene Sequence Analysis; Back Cover |
| Record Nr. | UNINA-9910786834803321 |
| Waretown, N.J. : , : Apple Academic Press, Inc., , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Comparative immunoglobulin genetics / / edited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario Canada
| Comparative immunoglobulin genetics / / edited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario Canada |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Waretown, N.J. : , : Apple Academic Press, Inc., , [2014] |
| Descrizione fisica | 1 online resource (258 p.) |
| Disciplina | 616.07/98 |
| Soggetto topico |
Immunoglobulins - Genetics
Immunoglobulin genes |
| ISBN |
1-77463-334-5
0-429-15995-1 1-4822-4355-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; About The Editors; Contents; List Of Contributors; List Of Abbreviations; Preface; Chapter 1 Variable Lymphocyte Receptor-based Adaptive Immunity In The Agnathan Sea Lamprey; Chapter 2 Agnathan Sea Lamprey Tetrapods; Chapter 3 The Immunoglobulin Genes Of Bats; Chapter 4 Marsupial And Monotreme Immunoglobulin Genetics; Chapter 5 Organization Of The Immunoglobulin Heavy- And Light-chain Loci In The Rat; Chapter 6 Generation Of The Antibody Repertoire In Rabbits: Role Of Gut-associated Lymphoid Tissues; Chapter 7 The Immunoglobulin Genes Of Domestic Swine
Chapter 8 Bovine Immunoglobulin Genetics: Novel Phylogenetic PerspectiveChapter 9 Informatic Tools For Immunoglobulin Gene Sequence Analysis; Back Cover |
| Record Nr. | UNINA-9910827405603321 |
| Waretown, N.J. : , : Apple Academic Press, Inc., , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Detection and quantification of antibodies to biopharmaceuticals [[electronic resource] ] : practical and applied considerations / / edited by Michael G. Tovey
| Detection and quantification of antibodies to biopharmaceuticals [[electronic resource] ] : practical and applied considerations / / edited by Michael G. Tovey |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2011 |
| Descrizione fisica | 1 online resource (442 p.) |
| Disciplina |
616.07/98
616.0798 |
| Altri autori (Persone) | ToveyMichael G |
| Soggetto topico |
Immunoglobulins - Analysis
Immunoassay |
| ISBN |
1-283-20385-5
9786613203854 1-118-07567-6 1-118-07568-4 1-118-07566-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Principals of risk assessment and monitoring of antibody responses to biopharmaceuticals / Eugen Koren, Erik Foehr, and Charles A. O'Neill -- Immunogenicity of therapeutic proteins : a regulatory perspective / Susan Kirshner -- Guidance on immunogenicity assessment of biologically-derived therapeutic proteins : an European perspective / Meenu Wadhwa and Robin Thorpe -- Japanese regulatory perspective on immunogenicity / Takao Hayakawa and Akiko Ishii -- Enzyme immunoassays and radioimmune assays for quantification of anti-TNF biopharmaceuticals and anti-drug antibodies / Klaus Bendtzen and Morten Svenson -- Confirmatory immunogenicity assays / Eric Wakshull and Daniel Coleman -- The use of pharmacodynamics as a surrogate marker for the detection of anti-drug neutralizing antibodies / Florian Deisenhammer -- Cell-based assays for the detection of neutralizing antibodies to interferon beta (IFN-?) and tumor necrosis factor-alpha (TNF-?) inhibitors / Anthony Meager -- Detection of neutralizing antibodies (NABs) to Interferon-beta by real time RT-PCR / Francesca Gilli and Antonio Bertolotto -- Competitive ligand binding assays for the detection of neutralizing antibodies / Bonnie Wu, George R. Gunn III, and Gopi Shankar --
The use of surface plasmon resonance for the detection and characterization of antibodies / Steven J. Swanson and Daniel Mytych -- Hypersensitivity reactions to biopharmaceuticals : detection and quantification of drug-specific IgE antibodies / Jørgen Dahlstrøm and Lennart Venemalm -- Standardization and validation of immunoassays and biophysical assays for the detection of anti-drug antibodies / Daniel Kramer -- Standardization and validation of cell-based assays for the detection of neutralizing anti-drug antibodies / Deborah Finco-Kent and Amy Grenham -- Standardization of neutralizing antibody unitge by bioassay design : constant antigen and constant antibody methodology / Sidney E. Grossberg, Yoshimi Kawade, and Leslie D. Grossberg -- Cut-points and performance characteristics for anti-drug antibody assays / Viswanath Devanarayan and Michael G. Tovey -- Dilutional linearity for neutralizing antibody assays / David Lansky and Carrie Wager -- Detection of neutralizing antibodies to biopharmaceuticals in the presence of high levels of circulating drug / Arno Kromminga and Michael G. Tovey. |
| Record Nr. | UNINA-9910139617103321 |
| Hoboken, N.J., : Wiley, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Detection and quantification of antibodies to biopharmaceuticals : practical and applied considerations / / edited by Michael G. Tovey
| Detection and quantification of antibodies to biopharmaceuticals : practical and applied considerations / / edited by Michael G. Tovey |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2011 |
| Descrizione fisica | 1 online resource (442 p.) |
| Disciplina | 616.07/98 |
| Altri autori (Persone) | ToveyMichael G |
| Soggetto topico |
Immunoglobulins - Analysis
Immunoassay |
| ISBN |
1-283-20385-5
9786613203854 1-118-07567-6 1-118-07568-4 1-118-07566-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Principals of risk assessment and monitoring of antibody responses to biopharmaceuticals / Eugen Koren, Erik Foehr, and Charles A. O'Neill -- Immunogenicity of therapeutic proteins : a regulatory perspective / Susan Kirshner -- Guidance on immunogenicity assessment of biologically-derived therapeutic proteins : an European perspective / Meenu Wadhwa and Robin Thorpe -- Japanese regulatory perspective on immunogenicity / Takao Hayakawa and Akiko Ishii -- Enzyme immunoassays and radioimmune assays for quantification of anti-TNF biopharmaceuticals and anti-drug antibodies / Klaus Bendtzen and Morten Svenson -- Confirmatory immunogenicity assays / Eric Wakshull and Daniel Coleman -- The use of pharmacodynamics as a surrogate marker for the detection of anti-drug neutralizing antibodies / Florian Deisenhammer -- Cell-based assays for the detection of neutralizing antibodies to interferon beta (IFN-?) and tumor necrosis factor-alpha (TNF-?) inhibitors / Anthony Meager -- Detection of neutralizing antibodies (NABs) to Interferon-beta by real time RT-PCR / Francesca Gilli and Antonio Bertolotto -- Competitive ligand binding assays for the detection of neutralizing antibodies / Bonnie Wu, George R. Gunn III, and Gopi Shankar --
The use of surface plasmon resonance for the detection and characterization of antibodies / Steven J. Swanson and Daniel Mytych -- Hypersensitivity reactions to biopharmaceuticals : detection and quantification of drug-specific IgE antibodies / Jrgen Dahlstrm and Lennart Venemalm -- Standardization and validation of immunoassays and biophysical assays for the detection of anti-drug antibodies / Daniel Kramer -- Standardization and validation of cell-based assays for the detection of neutralizing anti-drug antibodies / Deborah Finco-Kent and Amy Grenham -- Standardization of neutralizing antibody unitge by bioassay design : constant antigen and constant antibody methodology / Sidney E. Grossberg, Yoshimi Kawade, and Leslie D. Grossberg -- Cut-points and performance characteristics for anti-drug antibody assays / Viswanath Devanarayan and Michael G. Tovey -- Dilutional linearity for neutralizing antibody assays / David Lansky and Carrie Wager -- Detection of neutralizing antibodies to biopharmaceuticals in the presence of high levels of circulating drug / Arno Kromminga and Michael G. Tovey. |
| Record Nr. | UNINA-9910806999703321 |
| Hoboken, N.J., : Wiley, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Therapeutic monoclonal antibodies : from the bench to the clinic / / [edited by] Zhiqiang An
| Therapeutic monoclonal antibodies : from the bench to the clinic / / [edited by] Zhiqiang An |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, c2009 |
| Descrizione fisica | 1 online resource (924 p.) |
| Disciplina | 616.07/98 |
| Altri autori (Persone) | AnZhiqiang, Dr. |
| Soggetto topico |
Monoclonal antibodies - Therapeutic use
Immunotherapy |
| ISBN |
1-118-21026-3
1-282-38026-5 9786612380266 0-470-48540-X 0-470-48526-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | THERAPEUTIC MONOCLONAL ANTIBODIES; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; PART I ANTIBODY BASICS; PART II ANTIBODY SOURCES; PART III IN VITRO DISPLAY TECHNOLOGY; PART IV ANTIBODY ENGINEERING; PART V PHYSIOLOGY AND IN VIVO BIOLOGY; PART VI ANTIBODY CHARACTERIZATION; PART VII ANTIBODY EXPRESSION; PART VIII THERAPEUTIC ANTIBODIES; ABBREVIATIONS; INDEX |
| Record Nr. | UNINA-9910876863403321 |
| Hoboken, N.J., : John Wiley & Sons, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||