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Bisphenol A and phthalates [[electronic resource] ] : uses, health effects and environmental risks / / Bradley C. Vaughn, editor
| Bisphenol A and phthalates [[electronic resource] ] : uses, health effects and environmental risks / / Bradley C. Vaughn, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, 2010 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 615.9/51 |
| Altri autori (Persone) | VaughnBradley C |
| Collana | Chemical engineering methods and technology |
| Soggetto topico |
Bisphenol A - Toxicology
Bisphenol A - Environmental aspects Phthalate esters - Toxicology Phthalate esters - Environmental aspects |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61668-514-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910457927403321 |
| Hauppauge, N.Y., : Nova Science Publishers, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bisphenol A and phthalates [[electronic resource] ] : uses, health effects and environmental risks / / Bradley C. Vaughn, editor
| Bisphenol A and phthalates [[electronic resource] ] : uses, health effects and environmental risks / / Bradley C. Vaughn, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, 2010 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 615.9/51 |
| Altri autori (Persone) | VaughnBradley C |
| Collana | Chemical engineering methods and technology |
| Soggetto topico |
Bisphenol A - Toxicology
Bisphenol A - Environmental aspects Phthalate esters - Toxicology Phthalate esters - Environmental aspects |
| ISBN | 1-61668-514-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Review on analytical methods for the determination of regulated phthalates considering as priority substances by European and American regulations in the environment / Jean-Baptiste Baugros, Cécile Cren-Olivé and Marie-Florence Grenier-Loustalot -- Analytical methods for phthalates determination in biological and environmental samples : a review / P. Bermejo Barrera, M. C. Barciela Alonso, C. Pérez Feás, E. Peña Vázquez and P. Herbello Hermelo -- Preparation and characterization of phthalated hemicelluloses and cellulose derivatives / Chuan-Fu Liu, Feng Peng, Jun-Li Ren, Feng Xu and Run-Cang Sun -- Bisphenol a : uses, health effects and environmental risks / S. K. Nataraj and T. M. Aminabhavi -- Viscosity reduction of polycarbonates / Supakanok Thongyai -- Phthalates : identification, properties and health effects / Se-Kwon Kim and Yong Li -- Bisphenol a based polybenzoxazine and its tailored systems / K.S. Santhosh Kumar and C.P. Reghunadhan Nair -- DEHP-induced reproductive and developmental toxicity and PPAR / Yuki Ito, Yumi Hayashi and Tamie Nakajima -- Pitfalls in the analysis of Bisphenol A : sources and solutions / H. Gallart-Ayala, E. Moyano and M. T. Galceran -- Polymeric particles for the removal of endocrine disruptors / Changsheng Zhao, Kaiguang Yang, Zongbin Liu, Jin Chang and Norio Nishi. |
| Record Nr. | UNINA-9910779095503321 |
| Hauppauge, N.Y., : Nova Science Publishers, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bisphenol A and phthalates [[electronic resource] ] : uses, health effects and environmental risks / / Bradley C. Vaughn, editor
| Bisphenol A and phthalates [[electronic resource] ] : uses, health effects and environmental risks / / Bradley C. Vaughn, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, 2010 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 615.9/51 |
| Altri autori (Persone) | VaughnBradley C |
| Collana | Chemical engineering methods and technology |
| Soggetto topico |
Bisphenol A - Toxicology
Bisphenol A - Environmental aspects Phthalate esters - Toxicology Phthalate esters - Environmental aspects |
| ISBN | 1-61668-514-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Review on analytical methods for the determination of regulated phthalates considering as priority substances by European and American regulations in the environment / Jean-Baptiste Baugros, Cécile Cren-Olivé and Marie-Florence Grenier-Loustalot -- Analytical methods for phthalates determination in biological and environmental samples : a review / P. Bermejo Barrera, M. C. Barciela Alonso, C. Pérez Feás, E. Peña Vázquez and P. Herbello Hermelo -- Preparation and characterization of phthalated hemicelluloses and cellulose derivatives / Chuan-Fu Liu, Feng Peng, Jun-Li Ren, Feng Xu and Run-Cang Sun -- Bisphenol a : uses, health effects and environmental risks / S. K. Nataraj and T. M. Aminabhavi -- Viscosity reduction of polycarbonates / Supakanok Thongyai -- Phthalates : identification, properties and health effects / Se-Kwon Kim and Yong Li -- Bisphenol a based polybenzoxazine and its tailored systems / K.S. Santhosh Kumar and C.P. Reghunadhan Nair -- DEHP-induced reproductive and developmental toxicity and PPAR / Yuki Ito, Yumi Hayashi and Tamie Nakajima -- Pitfalls in the analysis of Bisphenol A : sources and solutions / H. Gallart-Ayala, E. Moyano and M. T. Galceran -- Polymeric particles for the removal of endocrine disruptors / Changsheng Zhao, Kaiguang Yang, Zongbin Liu, Jin Chang and Norio Nishi. |
| Record Nr. | UNINA-9910820941803321 |
| Hauppauge, N.Y., : Nova Science Publishers, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pesticide residues in food and drinking water : human exposure and risks / / edited by Denis Hamilton and Stephen Crossley
| Pesticide residues in food and drinking water : human exposure and risks / / edited by Denis Hamilton and Stephen Crossley |
| Pubbl/distr/stampa | New York, : J. Wiley, c2004 |
| Descrizione fisica | 1 online resource (379 p.) |
| Disciplina | 615.9/51 |
| Altri autori (Persone) |
HamiltonDenis
CrossleyStephen |
| Collana | Agrochemicals and plant protection |
| Soggetto topico |
Pesticides - Toxicology
Pesticide residues in food Drinking water - Contamination |
| ISBN |
1-280-26917-0
9786610269174 0-470-09160-6 1-59124-796-9 0-470-09161-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Pesticide Residues in Food and Drinking Water Human Exposure and Risks; Dedication; Contents; Contributors; Series Preface; Preface; 1 Introduction; 2 Environmental Fate of Pesticides and the Consequences for Residues in Food and Drinking Water; 3 Pesticide Metabolism in Crops and Livestock; 4 Effects of Food Preparation and Processing on Pesticide Residues in Commodities of Plant Origin; 5 Toxicological Assessment of Agricultural Pesticides; 6 Diets and Dietary Modelling for Dietary Exposure Assessment; 7 Chronic Intake; 8 Acute Intake; 9 Natural Toxicants as Pesticides
10 International Standards: The International Harmonization of Pesticide Residue Standards for Food and Drinking Water11 Explaining the Risks; Index |
| Record Nr. | UNINA-9910143514503321 |
| New York, : J. Wiley, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pesticide toxicology and international regulation [[electronic resource] /] / edited by Timothy C. Marrs and Bryan Ballantyne
| Pesticide toxicology and international regulation [[electronic resource] /] / edited by Timothy C. Marrs and Bryan Ballantyne |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2004 |
| Descrizione fisica | 1 online resource (584 p.) |
| Disciplina |
615.9/51
615.902 615.951 |
| Altri autori (Persone) |
MarrsTimothy C
BallantyneBryan |
| Collana | Current toxicology series |
| Soggetto topico |
Pesticides - Toxicology
Pesticides - Health aspects Pesticides - Government policy |
| ISBN |
1-280-26920-0
9786610269204 0-470-09166-5 0-470-09167-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Pesticide Toxicology and International Regulation; Contents; Preface; List of Contributors; Frequently Used Abbreviations; Toxicity Classifications and Hazard Ratings; 1 Pesticides: An Overview of Fundamentals; Definition and introductory generalizations; Major historical features; Classification and nomenclature; Exposure to pesticides; routes, monitoring, and protection; Health issues; Regulation of pesticides; References; Part I Insecticides; 2 Toxicology of Organochlorine Insecticides; Lindane/hexachlorocyclohexane (HCH); Cyclodiene and related insecticides; Toxaphene
DDT and its analoguesDDT; Mirex and chlordecone; Regulatory aspects; Summary; References; 3 Anticholinesterase Insecticides; Introduction; AChE; Major classes of anti-AChE insecticides; Toxicological consequences of AChE inhibition; Therapy for cholinergic toxicity; Regulatory aspects of anti-AChE insecticides; Acknowledgements; References; 4 Toxicology of Pyrethrins and Synthetic Pyrethroids; Usage and human exposure; Mechanisms of toxicity; Systemic poisoning; Pathology; Paraesthesia and local irritation; Developmental neurotoxicity; Reference values for synthetic pyrethroids; References 5 Toxicology of Miscellaneous InsecticidesIntroduction; Neuroactive insecticides; Insect growth regulators; Plant insecticides; Biochemical insecticides; References; Part II Fungicides, Herbicides and Growth Regulators; 6 Toxicology of Fungicides; Introduction; Halogenated substituted monocyclic aromatics; Dithiocarbamate fungicides; Dithiocarbamates; Ethylene bisdithiocarbamates; Benzimidazole/thiabendazole fungicides; Chloroalkylthiodicarboximides; Azoles; Morpholines; Carboxanilides (oxathiins); Organophosphates; Piperazines; Metallic fungicides; Miscellaneous; Aliphatic aldehydes ThiocarbonatesAntibiotics; Cinnamic acid class; Appendix: Complete listing of fungicides by chemical classes; References; 7 Toxicology of Herbicides; Herbicides; Inorganic herbicides; Bipyridylium herbicides; Phenoxy acid herbicides; Substituted anilines; Ureas and thioureas; Nitriles; Triazines and triazoles; Organic phosphorus herbicides; Defoliants and dessicants, and plant growth regulators; References; Part III Special Types of Pesticide; 8 Microbial Pesticides; Introduction; Regulatory approaches; Toxicity of particular organisms; References; 9 Biocides; Introduction Chemistry of biocides2,2-Dibromo-3-nitrilopropionamide (DBNPA); Methylenebisthiocyanate (MBT); Quarternary ammonium compounds (quats); 2-Bromo-2-nitropropane-1,3-diol (bronopol; BNP); iso-Thiazolones; Tetra-(hydroxymethyl)-phosphonium sulphate (THPS); Peracetic acid (PAA); Glutaraldehyde (GA); References; Part IV Residues; 10 Variability of Residues in Unprocessed Food Items and its Impact on Consumer Risk Assessment; Variability of pesticide residues; Maximum residue limits; Minor crops; Derivation of MRLs; Discovery of residue variability in UK crops; Further studies on variability Implications of variability and derivation of the variability factor |
| Record Nr. | UNINA-9910143510803321 |
| Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pesticide toxicology and international regulation [[electronic resource] /] / edited by Timothy C. Marrs and Bryan Ballantyne
| Pesticide toxicology and international regulation [[electronic resource] /] / edited by Timothy C. Marrs and Bryan Ballantyne |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2004 |
| Descrizione fisica | 1 online resource (584 p.) |
| Disciplina |
615.9/51
615.902 615.951 |
| Altri autori (Persone) |
MarrsTimothy C
BallantyneBryan |
| Collana | Current toxicology series |
| Soggetto topico |
Pesticides - Toxicology
Pesticides - Health aspects Pesticides - Government policy |
| ISBN |
1-280-26920-0
9786610269204 0-470-09166-5 0-470-09167-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Pesticide Toxicology and International Regulation; Contents; Preface; List of Contributors; Frequently Used Abbreviations; Toxicity Classifications and Hazard Ratings; 1 Pesticides: An Overview of Fundamentals; Definition and introductory generalizations; Major historical features; Classification and nomenclature; Exposure to pesticides; routes, monitoring, and protection; Health issues; Regulation of pesticides; References; Part I Insecticides; 2 Toxicology of Organochlorine Insecticides; Lindane/hexachlorocyclohexane (HCH); Cyclodiene and related insecticides; Toxaphene
DDT and its analoguesDDT; Mirex and chlordecone; Regulatory aspects; Summary; References; 3 Anticholinesterase Insecticides; Introduction; AChE; Major classes of anti-AChE insecticides; Toxicological consequences of AChE inhibition; Therapy for cholinergic toxicity; Regulatory aspects of anti-AChE insecticides; Acknowledgements; References; 4 Toxicology of Pyrethrins and Synthetic Pyrethroids; Usage and human exposure; Mechanisms of toxicity; Systemic poisoning; Pathology; Paraesthesia and local irritation; Developmental neurotoxicity; Reference values for synthetic pyrethroids; References 5 Toxicology of Miscellaneous InsecticidesIntroduction; Neuroactive insecticides; Insect growth regulators; Plant insecticides; Biochemical insecticides; References; Part II Fungicides, Herbicides and Growth Regulators; 6 Toxicology of Fungicides; Introduction; Halogenated substituted monocyclic aromatics; Dithiocarbamate fungicides; Dithiocarbamates; Ethylene bisdithiocarbamates; Benzimidazole/thiabendazole fungicides; Chloroalkylthiodicarboximides; Azoles; Morpholines; Carboxanilides (oxathiins); Organophosphates; Piperazines; Metallic fungicides; Miscellaneous; Aliphatic aldehydes ThiocarbonatesAntibiotics; Cinnamic acid class; Appendix: Complete listing of fungicides by chemical classes; References; 7 Toxicology of Herbicides; Herbicides; Inorganic herbicides; Bipyridylium herbicides; Phenoxy acid herbicides; Substituted anilines; Ureas and thioureas; Nitriles; Triazines and triazoles; Organic phosphorus herbicides; Defoliants and dessicants, and plant growth regulators; References; Part III Special Types of Pesticide; 8 Microbial Pesticides; Introduction; Regulatory approaches; Toxicity of particular organisms; References; 9 Biocides; Introduction Chemistry of biocides2,2-Dibromo-3-nitrilopropionamide (DBNPA); Methylenebisthiocyanate (MBT); Quarternary ammonium compounds (quats); 2-Bromo-2-nitropropane-1,3-diol (bronopol; BNP); iso-Thiazolones; Tetra-(hydroxymethyl)-phosphonium sulphate (THPS); Peracetic acid (PAA); Glutaraldehyde (GA); References; Part IV Residues; 10 Variability of Residues in Unprocessed Food Items and its Impact on Consumer Risk Assessment; Variability of pesticide residues; Maximum residue limits; Minor crops; Derivation of MRLs; Discovery of residue variability in UK crops; Further studies on variability Implications of variability and derivation of the variability factor |
| Record Nr. | UNINA-9910830395303321 |
| Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pesticide toxicology and international regulation / / edited by Timothy C. Marrs and Bryan Ballantyne
| Pesticide toxicology and international regulation / / edited by Timothy C. Marrs and Bryan Ballantyne |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2004 |
| Descrizione fisica | 1 online resource (584 p.) |
| Disciplina | 615.9/51 |
| Altri autori (Persone) |
MarrsTimothy C
BallantyneBryan |
| Collana | Current toxicology series |
| Soggetto topico |
Pesticides - Toxicology
Pesticides - Health aspects Pesticides - Government policy |
| ISBN |
1-280-26920-0
9786610269204 0-470-09166-5 0-470-09167-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Pesticide Toxicology and International Regulation; Contents; Preface; List of Contributors; Frequently Used Abbreviations; Toxicity Classifications and Hazard Ratings; 1 Pesticides: An Overview of Fundamentals; Definition and introductory generalizations; Major historical features; Classification and nomenclature; Exposure to pesticides; routes, monitoring, and protection; Health issues; Regulation of pesticides; References; Part I Insecticides; 2 Toxicology of Organochlorine Insecticides; Lindane/hexachlorocyclohexane (HCH); Cyclodiene and related insecticides; Toxaphene
DDT and its analoguesDDT; Mirex and chlordecone; Regulatory aspects; Summary; References; 3 Anticholinesterase Insecticides; Introduction; AChE; Major classes of anti-AChE insecticides; Toxicological consequences of AChE inhibition; Therapy for cholinergic toxicity; Regulatory aspects of anti-AChE insecticides; Acknowledgements; References; 4 Toxicology of Pyrethrins and Synthetic Pyrethroids; Usage and human exposure; Mechanisms of toxicity; Systemic poisoning; Pathology; Paraesthesia and local irritation; Developmental neurotoxicity; Reference values for synthetic pyrethroids; References 5 Toxicology of Miscellaneous InsecticidesIntroduction; Neuroactive insecticides; Insect growth regulators; Plant insecticides; Biochemical insecticides; References; Part II Fungicides, Herbicides and Growth Regulators; 6 Toxicology of Fungicides; Introduction; Halogenated substituted monocyclic aromatics; Dithiocarbamate fungicides; Dithiocarbamates; Ethylene bisdithiocarbamates; Benzimidazole/thiabendazole fungicides; Chloroalkylthiodicarboximides; Azoles; Morpholines; Carboxanilides (oxathiins); Organophosphates; Piperazines; Metallic fungicides; Miscellaneous; Aliphatic aldehydes ThiocarbonatesAntibiotics; Cinnamic acid class; Appendix: Complete listing of fungicides by chemical classes; References; 7 Toxicology of Herbicides; Herbicides; Inorganic herbicides; Bipyridylium herbicides; Phenoxy acid herbicides; Substituted anilines; Ureas and thioureas; Nitriles; Triazines and triazoles; Organic phosphorus herbicides; Defoliants and dessicants, and plant growth regulators; References; Part III Special Types of Pesticide; 8 Microbial Pesticides; Introduction; Regulatory approaches; Toxicity of particular organisms; References; 9 Biocides; Introduction Chemistry of biocides2,2-Dibromo-3-nitrilopropionamide (DBNPA); Methylenebisthiocyanate (MBT); Quarternary ammonium compounds (quats); 2-Bromo-2-nitropropane-1,3-diol (bronopol; BNP); iso-Thiazolones; Tetra-(hydroxymethyl)-phosphonium sulphate (THPS); Peracetic acid (PAA); Glutaraldehyde (GA); References; Part IV Residues; 10 Variability of Residues in Unprocessed Food Items and its Impact on Consumer Risk Assessment; Variability of pesticide residues; Maximum residue limits; Minor crops; Derivation of MRLs; Discovery of residue variability in UK crops; Further studies on variability Implications of variability and derivation of the variability factor |
| Record Nr. | UNINA-9910876726003321 |
| Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents [[electronic resource] /] / Subcommittee on Chronic Reference Doses for Selected Chemical Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents [[electronic resource] /] / Subcommittee on Chronic Reference Doses for Selected Chemical Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (320 p.) |
| Disciplina | 615.9/51 |
| Collana | The Compass series |
| Soggetto topico |
Chemical agents (Munitions) - Toxicology
Chemical agents (Munitions) - Environmental aspects Health risk assessment |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-18580-5
9786610185801 0-309-53928-5 0-585-19567-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910456128903321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents [[electronic resource] /] / Subcommittee on Chronic Reference Doses for Selected Chemical Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents [[electronic resource] /] / Subcommittee on Chronic Reference Doses for Selected Chemical Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (320 p.) |
| Disciplina | 615.9/51 |
| Collana | The Compass series |
| Soggetto topico |
Chemical agents (Munitions) - Toxicology
Chemical agents (Munitions) - Environmental aspects Health risk assessment |
| ISBN |
1-280-18580-5
9786610185801 0-309-53928-5 0-585-19567-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778747203321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents / / Subcommittee on Chronic Reference Doses for Selected Chemical Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents / / Subcommittee on Chronic Reference Doses for Selected Chemical Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (320 p.) |
| Disciplina | 615.9/51 |
| Collana | The Compass series |
| Soggetto topico |
Chemical agents (Munitions) - Toxicology
Chemical agents (Munitions) - Environmental aspects Health risk assessment |
| ISBN |
1-280-18580-5
9786610185801 0-309-53928-5 0-585-19567-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Review of the U.S. Army's Health Risk Assessments For Oral Exposure to Six Chemical-Warfare Agents -- Copyright -- OTHER REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY -- Other Reports of the Committee on Toxicology -- Preface -- Contents -- Summary -- EVALUATION OF THE ARMY'S INTERIM RFDS AND SFS -- CONCLUSIONS AND RECOMMENDATIONS -- GA -- GB -- GD -- VX -- SULFUR MUSTARD -- LEWISITE -- 1 Introduction -- REFERENCES -- 2 Derivation of Reference Doses -- REFERENCE-DOSE CALCULATION -- BENCHMARK DOSE -- UNCERTAINTY FACTORS -- CONCLUSIONS -- REFERENCES -- 3 Evaluation of the Army's Interim Reference Dose for GA -- DERIVATION OF THE ARMY'S INTERIM RFD -- APPROPRIATENESS OF THE CRITICAL STUDY -- APPROPRIATENESS OF CRITICAL END POINT -- APPROPRIATENESS OF UNCERTAINTY FACTORS -- EXTRAPOLATION FROM ANIMAL TO HUMAN -- PROTECTING SUSCEPTIBLE SUBPOPULATIONS -- EXTRAPOLATION FROM LOAEL TO NOAEL -- EXTRAPOLATION FROM SUBCHRONIC TO CHRONIC EXPOSURES -- DATA-BASE ADEQUACY -- MODIFYING FACTOR FOR ADDITIONAL UNCERTAINTY -- SUMMARY -- WEIGHT AND STRENGTH OF EVIDENCE -- CONCLUSIONS -- DATA GAPS AND RESEARCH RECOMMENDATIONS -- REFERENCES -- 4 Evaluation of the Army's Interim Reference Dose for GB -- DERIVATION OF THE ARMY'S INTERIM RFD -- APPROPRIATENESS OF THE CRITICAL STUDY -- APPROPRIATENESS OF CRITICAL END POINT -- APPROPRIATENESS OF UNCERTAINTY FACTORS -- EXTRAPOLATION FROM ANIMAL TO HUMAN -- PROTECTING SUSCEPTIBLE SUBPOPULATIONS -- EXTRAPOLATION FROM LOAEL TO NOAEL -- EXTRAPOLATION FROM SUBCHRONIC TO CHRONIC EXPOSURES -- DATA-BASE ADEQUACY -- MODIFYING FACTOR FOR ADDITIONAL UNCERTAINTY -- SUMMARY -- WEIGHT AND STRENGTH OF EVIDENCE -- CONCLUSIONS -- DATA GAPS AND RESEARCH RECOMMENDATIONS -- REFERENCES -- 5 EVALUATION OF THE ARMY'S INTERIM REFERENCE DOSE FOR GD -- DERIVATION OF THE ARMY'S INTERIM RFD -- APPROPRIATENESS OF THE CRITICAL STUDY.
APPROPRIATENESS OF CRITICAL END POINT -- APPROPRIATENESS OF UNCERTAINTY FACTORS -- EXTRAPOLATION FROM ANIMAL TO HUMAN -- PROTECTING SUSCEPTIBLE SUBPOPULATIONS -- EXTRAPOLATION FROM LOAEL TO NOAEL -- EXTRAPOLATION FROM SUBCHRONIC TO CHRONIC EXPOSURES -- DATA-BASE ADEQUACY -- MODIFYING FACTOR FOR ADDITIONAL UNCERTAINTY -- SUMMARY -- WEIGHT AND STRENGTH OF EVIDENCE -- CONCLUSIONS -- DATA GAPS AND RESEARCH RECOMMENDATIONS -- REFERENCES -- 6 Evaluation of the Army's Interim Reference Dose for VX -- DERIVATION OF THE ARMY'S INTERIM RFD -- APPROPRIATENESS OF THE CRITICAL STUDY -- APPROPRIATENESS OF CRITICAL END POINT -- APPROPRIATENESS OF UNCERTAINTY FACTORS -- EXTRAPOLATION FROM ANIMAL TO HUMAN -- PROTECTING SUSCEPTIBLE SUBPOPULATIONS -- EXTRAPOLATION FROM LOAEL TO NOAEL -- EXTRAPOLATION FROM SUBCHRONIC TO CHRONIC EXPOSURES -- DATA-BASE ADEQUACY -- MODIFYING FACTOR FOR ADDITIONAL UNCERTAINTY -- SUMMARY -- WEIGHT AND STRENGTH OF EVIDENCE -- CONCLUSIONS -- DATA GAPS AND RESEARCH RECOMMENDATIONS -- REFERENCES -- 7 Evaluation of the Army's Interim Reference Dose and Slope Factor For Sulfur Mustard -- EVALUATION OF THE ARMY'S INTERIM RFD -- DERIVATION OF THE ARMY'S INTERIM RFD -- APPROPRIATENESS OF THE CRITICAL STUDY -- APPROPRIATENESS OF CRITICAL END POINT -- APPROPRIATENESS OF UNCERTAINTY FACTORS -- Extrapolation from Animal to Human -- Protecting Susceptible Subpopulations -- Extrapolation from LOAEL to NOAEL -- Extrapolation from Subchronic to Chronic Exposures -- Data-Base Adequacy -- Modifying Factor for Additional Uncertainty -- Summary -- WEIGHT AND STRENGTH OF EVIDENCE -- EVALUATION OF THE ARMY'S INTERIM CANCER SLOPE FACTOR -- DERIVATION OF THE ARMY'S INTERIM CANCER SLOPE FACTOR -- APPROPRIATENESS OF METHOD USED -- WEIGHT AND STRENGTH OF EVIDENCE -- CONCLUSIONS -- DATA GAPS AND RESEARCH RECOMMENDATIONS -- REFERENCES. 8 Evaluation of the Army's Interim Reference Dose for Lewisite -- DERIVATION OF THE ARMY'S INTERIM RFD -- APPROPRIATENESS OF THE CRITICAL STUDY -- APPROPRIATENESS OF CRITICAL END POINT -- APPROPRIATENESS OF UNCERTAINTY FACTORS -- EXTRAPOLATION FROM ANIMAL TO HUMAN -- PROTECTING SUSCEPTIBLE SUBPOPULATIONS -- EXTRAPOLATION FROM LOAEL TO NOAEL -- EXTRAPOLATION FROM SUBCHRONIC TO CHRONIC EXPOSURES -- DATA-BASE ADEQUACY -- MODIFYING FACTOR FOR ADDITIONAL UNCERTAINTY -- SUMMARY -- WEIGHT AND STRENGTH OF EVIDENCE -- CONCLUSIONS -- DATA GAPS AND RESEARCH RECOMMENDATIONS -- REFERENCES -- Glossary -- Appendix A Health Risk Assessment for The Nerve Agent GA -- HEALTH RISK ASSESSMENT FOR THE NERVE AGENT GA -- DISCLAIMER -- PREFACE -- TABLE OF CONTENTS -- LIST OF TABLES -- 1. INTRODUCTION -- 1.1. PHYSICAL/CHEMICAL PROPERTIES -- 1.2. ENVIRONMENTAL FATE -- 1.2.1 Air -- 1.2.2 Water -- 1.2.3 Soil -- 2. MECHANISM OF ACTION -- 2.1 Effects of Organophosphate Agents on the Nervous System -- 2.2 Effect on Blood Cholinesterases -- 2.2.1 Intra- and Interspecies Variation in Blood Cholinesterase Activity -- 2.2.2 Potency of Nerve Agents as Cholinesterase Inhibitors -- 3. TOXICOLOGY -- 3.1 Introduction -- 3.2 Acute Toxicity -- 3.3 Subchronic Toxicity -- 3.4 Chronic Toxicity -- 3.5 Nervous System Toxicity -- 3.6 Developmental and Reproductive Effects -- 3.7 Carcinogenicity -- 3.8 Genotoxicity -- 4. ORAL REFERENCE DOSE FOR GA -- 4.1 Cholinesterase Inhibition as an RfD Endpoint -- 4.2 Derivation of the Oral RfD for GA -- 4.3 Overall Confidence in the Oral RfD -- 4.4 Comparison of the Oral RfD with Human Toxicity Data -- 5. CARCINOGENICITY ASSESSMENT -- 6. REFERENCES CITED -- APPENDIX A -- APPENDIX B -- APPENDIX C -- Appendix B Health Risk Assessment for The Nerve Agent GB -- HEALTH RISK ASSESSMENT FOR THE NERVE AGENT GB -- DISCLAIMER -- PREFACE -- TABLE OF CONTENTS. LIST OF TABLES -- 1. INTRODUCTION -- 1.1 PHYSICAL/CHEMICAL PROPERTIES -- 1.2. ENVIRONMENTAL FATE -- 1.2.1. Air -- 1.2.2 Water -- 1.2.3 Soil -- 2. MECHANISM OF ACTION -- 2.1 Effects of Organophosphate Agents on the Nervous System -- 2.2 Effect on Blood Cholinesterases -- 2.2.1 Intra- and Interspecies Variation in Blood Cholinesterase Activity -- 2.2.2 Potency of Nerve Agents as Cholinesterase Inhibitors -- 3. TOXICOLOGY -- 3.1 Introduction -- 3.2 Acute Toxicity -- 3.3 Subchronic Toxicity -- 3.4 Chronic Toxicity -- 3.5 Nervous System Toxicity -- 3.6 Developmental and Reproductive Effects -- 3.7 Carcinogenicity -- 3.8 Genotoxicity -- 4. ORAL REFERENCE DOSE FOR GB -- 4.1 Cholinesterase Inhibition as an RfD Endpoint -- 4.2 Derivation of the Oral RfD -- 4.3 Overall Confidence in the Oral RfD -- 4.4 Comparison of the RfD with Human Toxicity Data -- 5. CARCINOGENICITY ASSESSMENT -- 6. REFERENCES CITED -- APPENDIX A -- APPENDIX B -- Appendix C Health Risk Assessment for The Nerve Agent GD (Soman) -- HEALTH RISK ASSESSMENT FOR NERVE AGENT GD (SOMAN) -- DISCLAIMER -- PREFACE -- TABLE OF CONTENTS -- LIST OF TABLES -- 1. INTRODUCTION -- 1.1 PHYSICAL/CHEMICAL PROPERTIES -- 1.2 ENVIRONMENTAL FATE -- 1.2.1 Air -- 1.2.2 Water -- 1.2.3 Soil -- 2. MECHANISM OF ACTION -- 2.1 Effects of Organophosphate Agents on the Nervous System -- 2.2 Effect on Blood Cholinesterases -- 2.2.1 Intra-and Interspecies Variation in Blood Cholinesterase Activity -- 2.2.2 Potency of Nerve Agents as Cholinesterase Inhibitors -- 3. TOXICOLOGY -- 3.1 Introduction -- 3.2 Short-term Toxicity -- 3.3 Subchronic Toxicity -- 3.4 Chronic Toxicity -- 3.5 Nervous System Effects -- 3.6 Developmental and Reproductive Effects -- 3.7 Carcinogenicity and Genotoxicity -- 4. ORAL REFERENCE DOES FOR GD -- 4.1 Cholinesterase Inhibition as an RfD Endpoint -- 4.2 Derivation of the Oral RfD for GD. 4.3 Comparison of RfD with Toxicity Data -- 5. CARCINOGENICITY ASSESSMENT FOR GD -- 6. REFERENCES CITED -- APPENDIX A -- APPENDIX D Health Risk Assessment for The Nerve Agent VX -- HEALTH RISK ASSESSMENT FOR THE NERVE AGENT VX -- DISCLAIMER -- PREFACE -- TABLE OF CONTENTS -- LIST OF TABLES -- 1. INTRODUCTION -- 1.1. PHYSICAL/CHEMICAL PROPERTIES -- 1.2. ENVIRONMENTAL FATE -- 1.2.1 Air -- 1.2.2 Water -- 1.2.3 Soil -- 2. MECHANISM OF ACTION -- 2.1 Effects of Organophosphate Compounds on the Nervous System -- 2.2 Effect on Blood Cholinesterases -- 2.2.1 Intra- and Interspecies Variation in Blood Cholinesterase Activity -- 2.2.2 Potency of Nerve Agents as Cholinesterase Inhibitors -- 2.2.3 Cholinesterase Inhibition by VX -- 3. TOXICOLOGY -- 3.1 Introduction -- 3.2 Acute Toxicity -- 3.3 Subchronic Toxicity -- 3.4 Chronic Toxicity -- 3.5 Nervous System Toxicity -- 3.6 Developmental and Reproductive Effects -- 3.7 Carcinogenicity -- 3.8 Genotoxicity -- 4. ORAL REFERENCE DOSE FOR VX -- 4.1 Cholinesterase Inhibition as an RfD Endpoint -- 4.2 Derivation of the Oral RfD for VX -- 4.3 Overall Confidence in the RfD -- 4.4 Comparison of RfD with Human Toxicity Data -- 5. CARCINOGENICITY ASSESSMENT -- 6. REFERENCES CITED -- APPENDIX A -- APPENDIX B -- APPENDIX C -- APPENDIX C -- APPENDIX D -- Appendix E Health Risk Assessment for Sulfur Mustard (HD) -- HEALTH RISK ASSESSMENT FOR SULFUR MUSTARD (HD) -- DISCLAIMER -- PREFACE -- TABLE OF CONTENTS -- LIST OF TABLES -- 1. INTRODUCTION -- 1.1. PHYSICAL/CHEMICAL PROPERTIES -- 1.2. ENVIRONMENTAL FATE -- 1.2.1 Air -- 1.2.2 Water -- 1.2.3 Soil -- 2 MECHANISM OF ACTION -- 3. TOXICOLOGY -- 3.1 Introduction -- 3.2 Acute Toxicity -- 3.3 Subchronic Toxicity -- 3.4 Chronic Toxicity -- 3.4.1 Human Data -- 3.4.2 Animal Studies -- 3.5 Delayed Toxicity -- 3.6 Developmental and Reproductive Effects -- 3.7 Carcinogenicity. 3.7.1 Human Data. |
| Altri titoli varianti | Health risk assessments for oral exposure to six chemical-warfare agents |
| Record Nr. | UNINA-9910816118003321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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